BarbaraAMillerMD

PubMed

• 3 citations
  TRPC3 Antagonizes Pruritus in A Mouse Contact Dermatitis Model
  Katherine Beattie, Haowu Jiang, Mayank Gautam, Mary K. MacVittie, Barbara A. Miller
  The Journal of Investigative Dermatology. 2021-09-24
• 14 citations
  Glucocorticoids enhance the antileukemic activity of FLT3 inhibitors in FLT3-mutant acute myeloid leukemia.
  Melat T. Gebru, Jennifer M. Atkinson, Megan M. Young, Lijun Zhang, Zhenyuan Tang
  Blood. 2020-08-27
• 10 citations
  Expression Patterns of Immune Genes Reveal Heterogeneous Subtypes of High-Risk Neuroblastoma.
  Zhenqiu Liu, Christa N. Grant, Lidan Sun, Barbara A. Miller, Vladimir S. Spiegelman
  Cancers. 2020-06-30

Journal Articles

• Ca2+ entry via TRPM2 is essential for cardiac myocyte bioenergetics maintenance  
  Hoffman NE, Miller BA, Wang J, Elrod JW, Rajan S, Gao E, Song J, Zhang X-Q, Hirschler-Laszkiewicz I Shanmughapriya S, Koch WJ, Feldman A, Muniswamy M, Cheung JY, American Journal of Physiology: Heart and Circulatory Physiology, 1/1/2015
• A Splice Variant of the Human Ion Channel TRPM2-L Modulates Neuroblastoma Tumor Growth Through HIF-1/2alpha  
  Chen SJ, Hoffman NE, Shanmughapriya S, Bao L, Keefer K, Conrad K, Merali S, Takahashi Y, Abraham T, Hirschler-Laszkiewicz I, Wang J, Zhang X-Q, Song J, Barrero C, Shi ..., J. Biol. Chem, 1/1/2014
• TRPM2 mediates ischemic kidney injury and oxidant stress through Rac1  
  Gao G, Wang W, Tadagavadi R, Briley N, Love M, Miller BA, Reeves WB, J Clin Invest, 1/1/2014
• Severe Nondominant Hereditary Spherocytosis due to Uniparental Isodisomy at the SPTA1 Locus  
  Bogardus H, Schulz VP, Maksimova Y, Miller BA, Li P, Forget B, Gallagher PG, Haematologica, 1/1/2014
• TRPM2 Channels Protect Against Cardiac Ischemia-Reperfusion Injury: Role of Mitochondria  
  Miller BA, Hoffman NE, Merali S, Zhang X-Q, Wang J, Rajan S, Shanmughapriya S, Gao E, Barrero CA, Mallilankaraman K, Song J, Gu T, Hirschler-Laszkiewicz I, Koch WJ, F..., J. Biol. Chem, 1/1/2014
• The Second Member of the Transient Receptor Potential-Melastatin (TRPM2) Channel Family Protects Hearts from Ischemia-Reperfusion Injury  
  Miller BA, Wang J, Hirschler-Laszkiewicz I, Gao E, Song J, Zhang X-Q, Koch WJ, Muniswamy M, Mallilankaraman K, Gu T, Chen S-J, Keefer K, Conrad K, Feldman AM, Cheung JY, American Journal of Physiology: Heart and Circulatory Physiology, 1/1/2013
• Role of TRPM2-S in Cell Proliferation and Susceptibility to Oxidative Stress  
  Chen SJ, Zhang W, Tong Q, Conrad K, Hirschler-Laszkiewicz I, Bayerl M, Kim J, Cheung JY, Miller BA, American Journal of Physiology: Cell Physiology, 1/1/2013
• The Encyclopedia of Biological Chemistry  
  Miller, BA, 1/1/2013
• TRPM2 Ca2+-Channel Regulates Energy Balance and Glucose Metabolism  
  Zhang Z, Zhang W, Jung DY, Ko HJ, Lee YJ, Friedline R, Lee E, Jun J, Ma Z, Kim F, Tsitsilianos N, Chapman K, Morrison A, Cooper MP, Miller BA, Kim JK, American Journal of Physiology: Endocrinology and Metabolism, 1/1/2012
• Trpc2 Depletion Protects Red Blood Cells from Oxidative Stress-Induced Hemolysis  
  Hirschler-Laszkiewicz I, Zhang W, Keefer K, Conrad K, Tong Q, Chen, S-J, Bronson S, Cheung JY, and Miller BA, Experimental Hematology, 1/1/2012
• The Transient Receptor Potential (TRP) Channel TRPC3 TRP Domain and AMP-Activated Protein Kinase Binding Site Are Required for TRPC3 Activation by Erythropoietin  
  Hirschler-Laszkiewicz I, Tong Q, Waybill K, Conrad K, Keefer, K, Zhang W, Chen SJ, Cheung JY, Miller BA, J. Biol. Chem, 1/1/2011
• TRP Channels as Mediators of Oxidative Stress  
  Miller, BA, Zhang W, Advances in Experimental Medicine and Biology, 1/1/2011
• TRPC3 activation by Erythropoietin is modulated by TRPC6  
  Hirschler-Laszkiewicz I, Tong Q, Conrad K, Zhang W, Flint W, Barber A, Barber D, Cheung JY, Miller BA, J. Biol. Chem, 1/1/2009
• TRPC3 is the Epo-regulated Calcium Channel in Human Erythroid Cells  
  Tong Q, Hirschler-Laszkiewicz I, Zhang W, Conrad K, Neagley DW, Barber DL, Cheung JY, Miller BA, J. Biol. Chem, 1/1/2008
• Regulation of the TRP Channel TRPM2 by the Tyrosine Phosphatase PTPL1  
  Zhang W, Tong Q, Conrad K, Wozney J, Cheung JY, Miller BA, American Journal of Physiology: Cell Physiology, 1/1/2007
• Regulation of the TRP Channel TRPM2 by the Ca2+-Sensor Calmodulin  
  Tong Q, Zhang, W, Conrad K, Cheung JY, Peterson BZ, Miller BA, J. Biol. Chem, 1/1/2006
• TRPM2 is an Ion Channel Which Modulates Hematopoietic Cell Death Through Activation of Caspases and PARP Cleavage  
  Zhang W, Hirschler-Laskiewicz I, Tong Q, Conrad K, Sun S-C, Penn L, Barber DL, Stahl, R, Carey DJ, Cheung JY, Miller BA, American Journal of Physiology: Cell Physiology, 1/1/2006
• The Role of TRP Channels in Oxidative Stress-Induced Cell Death  
  Miller, BA, Journal of Membrane Biology, 1/1/2006
• Amyloid beta-peptide (1-42) and hydrogen peroxide-induced Toxicity are Mediated by TRPM2 in Rat Primary Striatal Cultures  
  Fonfria E, Marshall ICB, Boyfield I, Skaper SD, Hughes JP, Owen DE, Zhang W, Miller BA, Benham CD, McNulty S, Journal of Neurochemistry, 1/1/2005
• Identification of an N-terminal TRPC2 Splice Variant Which Inhibits Calcium Influx  
  Chu X, Tong Q, Wozney J, Zhang W, Cheung JY, Conrad K, Mazack V, Stahl R, Barber DL, Miller BA, Cell Calcium, 1/1/2005
• Erythropoietin Receptor Y479 Couples to ERK1/2 Activation Via Recruitment of Phospholipase Cgamma  
  Halupa A, Chohan M, Stickle NH, Beattie BK, Miller BA, Barber DL, Experimental Cell Research, 1/1/2005
• Inhibition of TRPM2 Function by PARP inhibitors protects cells from oxidant-stress induced cell death  
  Miller, B.A., Br. J. Pharmacol, 1/1/2004
•  
  Tong Q, Chu X, Cheung JY, Conrad K, Stahl R, Barber DL, Mignery G, Miller BA, Amer. J. Physiology: Cell Physiology, 1/1/2004
• Interaction of TRPC2 and TRPC6 in Erythropoietin Modulation of Calcium Influx  
  Chu X, Tong Q, Cheung JY, Wozney J, Conrad K, Mazack V, Zhang W, Stahl R, Barber DL, Miller BA, J. Biol. Chem, 1/1/2004
• A Novel TRPM2 Isoform Inhibits Calcium Influx and Susceptibility to Cell Death  
  Zhang W, Chu X, Tong Q, Cheung JY, Conrad K, Masker K, Miller BA, J. Biol. Chem, 1/1/2003
• Join now to see all

Books/Book Chapters

• Handbook of Experimental Pharmacology: Mammalian Transient Receptor Potential (TRP) Cation Channels 
  Chapter: TRPC2 
  Page 53.0 - 65.0Miller, BAEditors: Nilus, B. and Flockerzi, V.2014
• Methods in Pharmacology and Toxicology: TRP Channels in Drug Discovery 
  Chapter: TRPM2 Function and Potential as a Drug Target 
  Page 89.0 - 102.0Miller, BAEditors: Szallasi A.2012
• The Encyclopedia of Biological Chemistry 
  Chapter: Hematopoietin Receptors 
  Miller, BA, and Cheung, JYEditors: Lennarz W, Lane, MD, Exton, J.2004
• The Regulation of Hemoglobin Switching 
  Chapter: Pharmacologic prevention and reversal of globin gene switching 
  Page 425.0 - 436.0Perrine SP, Faller DV, Swerdlow P, Sytkowski R, Qin G, Miller BA, Olivieri N, Rudolph AM, Kan YWEditors: Stamatoyannopoulos G, Nienhuis A.1991
• Current Therapy in Neonatal/Perinatal Medicine 
  Chapter: Neonatal thrombocytopenia 
  Page 370.0 - 372.0Miller BAEditors: N.M. Nelson.1990
• Join now to see all

Abstracts/Posters

• Human Ion Channel TRPM2-L Protects Cell Viability through Modulation of Mitochondrial Function
  Chen SJ, Bao L, Keefer K, Conrad K, Hirschler-Laszkiewicz I, Hoffman NE, Wang J, Shi Y, Takahashi Y, Bayerl M, Wang HG, Muniswamy M, Cheung JY, Miller BA, Pediatric Research Day, 1/1/2014
• Pediatric Hematology/Oncology 2013
  Miller, BA, Four Diamonds Advisory Board Meeting, HMC, 1/1/2013
• Xenograft Model to Assess TRPM2 Function in Chemotherapy Responsiveness
  Hirschler-Laszkiewicz I, Zhang W, Keefer K, Conrad K, Chen S, Miller BA, Pediatric Research Day, HMC, 1/1/2012
• The Role of TRPM2-S in Cell Proliferation and Susceptibility to Oxidative Stress in Neuroblastoma
  Chen S, Conrad K, Hirschler-Laszkiewicz I, Keefer K, Miller BA, Pediatric Research Day, HMC, 1/1/2012
• TRPM2 Channel Function in Cancer
  Miller, BA, Four Diamonds Scientific External Advisory Board, HMC, 1/1/2012
• TRPM2 Channel Function and Potential as a Drug Target
  Miller, BA, Penn State Cancer Institute Experimental Therapeutics Program, HMC, 1/1/2011
• Pediatric Oncology at Penn State: Past, Present, and Future
  Miller, BA, Siemans Visit, HMC, 1/1/2011
• Expression and Function of the Ion Channel TRPM2 in Neuroblastoma
  Barbour M, Chen S, Zhang W, Miller BA, Pediatric Research Day, HMC, 1/1/2010
• Regulation of Diet-Induced Obesity and Insulin Resistance by TRPM2 Ca2+-Channels
  Ko HJ, Zhang Z, Zhang W, Jung DY, Lee Y, Morrison AD, Chapman K, Shapland E, Cooper MP, Miller BA, Kim JK, American Diabetes Association, Orlando, Florida, 1/1/2010
• TRPM2 Deletion Improves Insulin Sensitivity and Cardiac Glucose Metabolism in Mice
  Zhang W, Zhang Z, Jung DY, Kim J, Miller, BA, Pediatric Research Day, HMC, 1/1/2010
• Two nonselective calcium channels - TRPC3 and TRPC6 are Important in Erythropoietin Signaling during Erythroid Differentiation
  Hirschler-Laszkiewicz I, Tong Q, Conrad K, Zhang W, Chen S, Keefer K, Cheung J, Miller BA, Pediatric Research Day, HMC, 1/1/2010
• The Role of TRPM2 Splice Variants in Oxidative-Stress Medicated Cell Death in Neuroblastoma
  Chen S, Tong Q, Conrad K, Zhang W, Miller BA, Pediatric Research Day, HMC, 1/1/2010
• The TRP domain of TRPC3 is essential but not sufficient for Erythropoietin-regulated activation of TRPC3
  Hirschler-Laskiewicz I, Tong Q, Conrad K, Hurst N, Zhang W, Chen S, Keefer K, and Miller BA, The Biophysical Society, Boston, MA, 1/1/2009
• TRPM2 Deletion Improves Cardiac Insulin Sensitivity by Increasing IRS-1 and AKT Activity in Vitro
  Zhang W, Zhang Z, Kim JK, and Miller BA, Pediatric Research Day, HMC, 1/1/2008
• TRPC3 Activation by Erythropoietin is Modulated by TRPC6
  Hirschler-Laskiewicz I, Tong Q, Conrad K, Zhang W, Flint W, Cheung J, Barber AJ, and Miller BA, Pediatric Research Day, HMC, 1/1/2008
• In Vivo Roles of TRPC3 and TRPM2 in Oxidative Stress
  Miller, BA, 2nd International Congress on Cell Membranes and Oxidative Stress, Isparta, Turkey, 1/1/2008
• Homozygous Deletion of TRPM2 Ca2+-Channels Increases Insulin Sensitivity and Cardiac Glucose Metabolism in Vivo in Mice
  Zhang Z, Zhang W, Jung DE, Ma Z, Kim F, Miller BA, Kim JK, American Diabetes Association, San Francisco, CA, 1/1/2008
• Role of TRP Channels in Cell Death
  Miller, BA, Penn State Cancer Institute Experimental Therapeutics Program, 1/1/2007
• Activation of TRPC3 by Erythropoietin is regulated Through Tyrosine Phosphorylation
  Hirschler-Laszkiewicz IM, Schworer SA, Conrad K, Tong Q, Zhang W, Mostoller K, Smithgall TE, Cheung JY, Miller BA, The Biophysical Society, Baltimore, Maryland, 1/1/2007
• Regulation of the TRP Channel TRPM2 by the Tyrosine Phosphatase PTPL1
  Zhang W, Tong Q, Wozney J, Conrad K, Cheung JY, Miller BA, The Biophysical Society, Baltimore, Maryland, 1/1/2007
• TRPC3 activation by Erythropoietin is Modulated by TRPC6. Keystone Symposium: The Transient Receptor Potential Ion Channel Superfamily
  Hirschler-Laskiewicz I, Tong Q, Conrad K, Zhang W, and Miller BA, Keystone Symposia, Breckenridge, Colorado, 1/1/2007
• Regulation of the TRP Channel TRPM2 by the Ca2+-Sensor Calmodulin
  Tong Q, Zhang W, Conrad K, Cheung JY, Peterson B, Miller BA, The Biophysical Society, Salt Lake City, Utah, 1/1/2006
• Role of the Ion Channel TRPM2 in Cell Death Mediated by Oxidative Stress and TNFalpha
  Miller BA, Biochemistry and Molecular Biology Seminar, PSU College of Medicine, 1/1/2005
• TRPM2 is an Ion Channel Which has a Critical Role in Hematopoietic Proliferation and Susceptibility to Cell Death
  Zhang W, Hirschler-Lasziewicz I, Tong Q, Cheung JY, Miller BA, Biophysical Society, Long Beach, CA, 1/1/2005
• TRPM2 mediates oxidative stress-induced cell death in rat striatum
  Fonfria E, Boyfield I, Marshall ICB, Hughes J, Cusdin F, Kelsell RE, Skepper JN, Benham CD, Miller BA, McNulty S, Physiological Society of the UK, Glascow, Scotland, 1/1/2004
• Join now to see all

Lectures

• TRPM2: Novel Findings in Mice and Men 
  1/1/2012
• Calcium Transport in Health and Disease 
  Penn State University College of Medicine, Hershey, PA - 1/1/2009
• Role of TRP Channels in Cell Proliferation and Death 
  University of Illinois in Chicago, Chicago, IL - 1/1/2009
• Role of the Ion Channel TRPM2 in Oxidative Stress-Induced Cell Death 
  Oklahoma State University, Stillwater, Oklahoma - 1/1/2007
• Role of the Ion Channel TRPM2 in Cell Death 
  Medical University of Ohio, Toledo, Ohio - 1/1/2006
• Role of the Channel TRPM2: Function in Cell Injury and Cancer 
  1/2./2014
• Join now to see all