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Office
122 West Third Street
Frederick, MD 21701Phone+1 240-215-7556
Summary
- Present Activities: Retired; Member of the Hood College Board of Trustees; Volunteer Emeritus at U.S.A.M.R.I.I.D.; Member Board of Directors at Hospice of Frederick County; Member Board of Kiwanis Club of Frederick Foundation; Volunteer with "Blessings In A Backpack" and Bicycle Tourism anywhere in the world.
Previous Positions [2007 04-30 - 2016 10-31 DA Civilian;
Former Director, Office of Human Use and Ethics and Research Integrity Officer: (a.) Participate in the development of Institute Policy on Ethics in Research. (b.) Nurture the Human Subjects Protection Program. (c.) Advise senior officials on ethics-sensitive issues that impact institute operations. (d.) Supervise the Human Protection Administrator and other office staff. (e.) Serve as the point of contact for HIPAA compliance. (f.) Conduct inquiries and investigations upon receipt of allegations of scientific misconduct or improper researcher behavior.
Former Member, USAMRIID and HQ USAMRMC IRBs: (a.) Attend and participate in all convened IRB meetings. (b.) Prepare timely and intensive fact-finding reviews of minimal risk protocols that qualify for expedited review; (c.) Conduct substantive continuing review of active protocols; (d.) Investigate issues arising during conduct of studies; and (e.) Participate in Local and National Meetings of Organizations whose focus is Protecting the Rights and Welfare of Human Volunteer Subjects.
Collaborator in Scientific Investigations (a.) Design research protocols that elucidate the mechanisms of immunity for existing vaccines and second generation recombinant products, particularly the forms of immunity which are essential for protection against aerosol exposure. (b.) Consult with other investigators on technologies which may be applied to improve vaccine efficacy. (c.) Initiate intramural and extramural collaborations for novel research approaches.
Education & Training
- Johns Hopkins University School of MedicinePost-Doctoral Fellowship, 1972 - 1974
- Johns Hopkins UniversityResidency, Pathology-Anatomic and Clinical, 1970 - 1974
- University of Maryland School of MedicineClass of 1970
- Wagner CollegeB.S., Biology, 1962 - 1966
Certifications & Licensure
- MD State Medical License 1976 - 2019
- American Board of Pathology Anatomic Pathology
Awards, Honors, & Recognition
- Superior Civilian Service Medal Department of Army, 2016
- Legion of Merit Medal U.S. Army, 2007
- Honorary Doctoral Degree, PhD in Philosophy Wagner College Staten Island NY, 2003
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Publications & Presentations
PubMed
- 67 citationsTNF and lymphotoxin beta cooperate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodesDmitry V. Kuprash, Alimzhanov Mb, Alexei V. Tumanov, Arthur O. Anderson, Klaus Pfeffer
Journal of Immunology. 1999-12-15 - 915 citationsThe neutrophil-activating protein (NAP-1) is also chemotactic for T lymphocytes.Christian G. Larsen, Arthur O. Anderson, Ettore Appella, Joost J. Oppenheim, Kouji Matsushima
Science. 1989-03-17 - 119 citationsRabbit IgH sequences in appendix germinal centers: VH diversification by gene conversion-like and hypermutation mechanisms.Peter D. Weinstein, Arthur O. Anderson, Rose G. Maget
Immunity. 1994-11-01
Journal Articles
- Ultrastructural localization of extracellular matrix proteins of the lymph node cortex: evidence supporting the reticular network as a pathway for lymphocyte migration...Sobocinski, G.P., K. Toy, W.F. Bobrowski, S. Shaw, A.O. Anderson, and E.P. Kaldjian, BioMed Central BMC Immunology, 1/1/2010
- Reduced CD45 expression levels protect mice from lethal effects of Ebola infectionPanchal, R.G., S. Bradfute, R. Ulrich, K. Warfield, G. Ruthel, B.D. Peyser, D. Lane, T.A. Kenny, P.L. Iversen, A.O. Anderson, L.C. Cantley, W.C. Raschke, S. Bavari, Cell Host & Microbe, 1/1/2009
- Reduced expression of CD45 protein tyrosine phosphatase provides protection against anthrax pathogenesisR.G. Panchal, R. Ulrich, S.B. Bradfute, D. Lane, G. Ruthel, T.A. Kenny, P.L. Iversen, A.O. Anderson, R. Gussio, W.C. Raschke, S. Bavari, J. Biol. Chem, 1/1/2009
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Books/Book Chapters
Lectures
- What your lymph nodes do besides swell up when you get monoFort Detrick, MD - 1/3/2012
- Anatomy and Physiology Of The Lymph Node: An Immunophotojournalist's POVMarriott Waterfront Hotel, Baltimore, MD - 1/31/2010
- Introductory Lectures to Quarterly Lecture Series on Responsible Conduct in Research: 1. Ethical Decision Making Primer; and, 2. Research Misconduct: How to Recognize ...Dalrymple Conference Room, USAMRIID, Frederick, MD - 1/29/2010
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Authored Content
- ETHICAL ISSUES IN THE DEVELOPMENT OF DRUGS AND VACCINES FOR BIODEFENSEJanuary 2018
Press Mentions
- AcclaimNovember 17th, 2016
Committees
- Member, Pre-Med Advisory Committee 1980 - 1983
- Chairman, Human Use Committee [IRB] 1975 - 2007
Research History
- Department Chief and Principal InvestigatorDept.Respiratory and Mucosal Immunity. Studies optimizing vaccine antigens for producing protective immunity against high hazard pathogens our department discovered mucosal/peripheral crossregulation CR. Specific adjuvants abrogate CR & give complete immunity regardless of local or aerosol exposure.1983 - 1995
- Collaborating InvestigatorWith Drs. John C. Cebra & Don Rubin I found a method to enhance ant-viral mucosal immunity with a lipoidal amine adjuvant (which formed liposomes when added to FDA-approved soybean lipid emulsion [Intralipid]). The research also discovered the viral protein responsible for tropism of the test virus1980 - 1983
- Principal InvestigatorCellular Phenomena in Lymphatic Tissues During Immune Responses: The research identifed molecularly-defined non-toxic "adjuvants" that enhanced immunity by affecting the rate of migration of naive lymphocytes through lymphatic tissues based on in vitro evidence of chemotaxis.1974 - 1980
Professional Memberships
- Member
- American Association of ImmunologistsMember
- American Society of Investigative PathologistsMember
- Applied Research Ethics National AssociationMember
- Public Responsibility In Medicine & Research [PRIM&R]Member
External Links
- Curriculum Vitaehttp://artnscience.us/AO_Anderson_CV/index.html
- Home Pagehttp://artnscience.us/index.html
- Immunology Lecture Noteshttp://artnscience.us/Immune_System/index.html
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