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Office
Bristol Myers Squibb
1000 Sierra Point Pkwy
Brisbane, CA 94005Phone+1 415-717-4342
Summary
- Accomplished Physician and Leader in Clinical Development, Translational Medicine and Pathology pharma/biotech R and D with significant therapeutic focus in antibody drug conjugates and immuno-oncology/oncology in select solid tumors and malignant hematology, and immunology. Leadership experience up to Executive Director with site head and Interim Chief Medical Officer responsibilities. Strengths include programmatic/strategic and project development, multi-site project management, clinical informatics, effective communications with physicians/ key thought leaders, in-depth health industry knowledge, superior analytical and financial skills, and significant experience as a published scientific/medical author and speaker.
Education & Training
- University of California (San Francisco)Fellowship, Hematopathology, 1994 - 1995
- University of California (San Francisco) School of MedicineResidency, Laboratory Medicine (Clinical Pathology), 1993 - 1994
- Stanford Health CareFellowship, Immunopathology, 1991 - 1993
- Stanford Health Care-Sponsored Stanford University Surgical PathologyFellowship, Selective Pathology, 1990 - 1991
- Stanford Health Care-Sponsored Stanford UniversityResidency, Pathology-Anatomic and Clinical, 1988 - 1990
- University of ChicagoInternship, Internal Medicine, 1987 - 1988
- Stanford University School of MedicineClass of 1987
Certifications & Licensure
- CA State Medical License 1988 - 2025
- FL State Medical License 2012 - 2016
- NJ State Medical License 2012 - 2015
- American Board of Pathology Anatomic Pathology
- American Board of Pathology Clinical Pathology
- American Board of Pathology Immunopathology
Awards, Honors, & Recognition
- Stanford Medical Scholar Stanford University, 1987
- Research Honors Award Stanford University, 1987
Clinical Trials
- A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma Start of enrollment: 2015 Jun 01
- A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Breast Cancer Start of enrollment: 2015 Jul 01
- A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG Start of enrollment: 2017 Sep 26
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Publications & Presentations
PubMed
- 4 citationsDisappearance of MMR-deficient subclones after controlled IL-12 and PD-1 inhibition in a glioma patient.Matthew McCord, Rimas V. Lukas, Christina Amidei, Nathan Demars, Arnold Gelb
Neuro-Oncology Advances. 2021-01-01 - 168 citationsRegulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial.E. Antonio Chiocca, John S. Yu, Rimas V. Lukas, Isaac H. Solomon, Keith L. Ligon
Science Translational Medicine. 2019-08-14 - 65 citationsAvelumab (anti-PD-L1) as first-line switch-maintenance or second-line therapy in patients with advanced gastric or gastroesophageal junction cancer: Phase 1b results f...Hyun Cheol Chung, Hendrik Tobias Arkenau, Jeeyun Lee, Sun Young Rha, Do Youn Oh
Journal for Immunotherapy of Cancer. 2019-02-04
Journal Articles
- Posttransplant lymphoproliferative disorders in patients undergoing pediatric liver transplantation: a clinicopathologic study.Koh BY, Rosenthal P, Medeiros LJ. Zhou Y, Osorio RY, Roberts JP, Ascher NL, Gelb AB, Cancer
Books/Book Chapters
Press Mentions
- Metabolomics and Precision MedicineApril 14th, 2019
Committees
- Delegate, Clinical and Laboratories Standards Institute 2011 - Present
Industry Relationships
- Senior Clinical Trial Physician, Bristol-Myers Squibb2020 - Present
- Executive Director, Ziopharm Oncology, Inc.Clinical Development & Medical Monitor2018 - 2020
- Senior Director, EMD Serono R&D InstituteGlobal Early Development2015 - 2018
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