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Office
44 Binney Street
Room D1B30 Dfci Dana Farber Cancer Institute
Boston, MA 02115Phone+1 617-632-4894Fax+1 617-582-7890
Education & Training
- Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 1982 - 1987
- UMass Chan Medical SchoolResidency, Internal Medicine, 1979 - 1982
- University of Massachusetts Medical SchoolClass of 1979
- Brandeis UniversityB.A., Biology, Cum Laude, 1974
Certifications & Licensure
- NH State Medical License 2009 - Present
- MA State Medical License 1981 - 2025
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- America's Top Doctors Castle Connolly, 2011-2014
- Boston Magazine Castle Connolly, 2010-2013
- America's Top Doctors for Cancer Castle Connolly, 2010-2013
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Clinical Trials
- Xcellerated T CellsTM for Non-Hodgkin's Lymphoma (NHL) Patients Start of enrollment: 2004 Mar 01
- Autologous or Donor Stem Cell Transplantation in Treating Patients With Recurrent Non-Hodgkin's Lymphoma (BMT CTN 0202) Start of enrollment: 2004 Aug 01
- Study of Dynavax's 1018 ISS, Following Rituxan in Patients With B-Cell Follicular Lymphoma Start of enrollment: 2004 Jul 01
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Publications & Presentations
PubMed
- 48 citationsThe Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.Elizabeth C Townsend, Mark A Murakami, Alexandra Christodoulou, Amanda L Christie, Johannes Köster
Cancer Cell. 2016-04-11 - 33 citationsTGFβ-mediated activation of Smad1 in B-cell non-Hodgkin's lymphoma and effect on cell proliferationOlivier Munoz, Falko Fend, R de Beaumont, Hervé Husson, Anne Astier
Leukemia. 2004-12-01 - 276 citationsSelective induction of B7/BB-1 on interferon-γ stimulated monocytes: A potential mechanism for amplification of T cell activation through the CD28 pathway☆Arnold S. Freedman, Gordon J. Freeman, K Rhynhart, Lee M. Nadler
Cellular Immunology. 1991-10-15
Journal Articles
- Rethinking prognosis and therapy for follicular lymphomaJacobson CA, Freedman AS, J Clin Oncol, 1/1/2015
- Obatoclax in combination with fludarabine and rituximab is well-tolerated and shows promising clinical activity in relapsed chronic lymphocytic leukemiaBrown JR, Tesar B, Yu L, Werner L, Takebe N, Mikler E, Reynolds HM, Thompson C, Fisher DC, Neuberg D, Freedman AS, Leuk Lymphoma, 1/1/2015
- Is observation dead in follicular lymphoma? Still appropriateJacobson CA, Freedman AS, J National Comprehensive Cancer Center Network, 1/1/2015
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Books/Book Chapters
Abstracts/Posters
- Risk alleles identified in genome-wide association studies are associated with expression quantitative trait loci in chronic lymphocytic leukemia.Tesar B, Werner L, Hanna M, Improgo MR, Pochet N, Fernandes SM, Macconaill L, Regev A, Freedman, AS, Neuberg DS, Freedman ML, Brown JR, Blood; ASH, 1/1/2012
- Prognostic factors for patients with diffuse large B cell lymphoma and transformed indolent lymphoma undergoing autologous stem cell transplantation in the PET era.Welch S, Armand P, Kim HT, LaCasce AS, Jacobsen E, Davids MS, Jacobson CA, Fisher DC, Brown JR, Freedman AS, Coughlin E, Chen YA, Blood; ASH, 1/1/2012
- Anti-CD40 monoclonal antibody lucatumumab exhibits anti-tumor activity in follicular lymphoma and other lymphoma subtypes: phase I/II preliminary findings.Freedman A, Kuruvilla J, Assouline S, Engert A, Heo D, Solal-Celigny P, Corradini P, Verhoef G, Younes A, Bendiske J, Ewald B, Dey J, Baeck J, Bilic S, Rediske J, and ..., Ann Oncol; International Conference on Malignant Lymphoma, 1/1/2011
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Lectures
- PD-1 Blockade with Pembrolizumab for Classical Hodgkin Lymphoma after Autologous Stem Cell Transplantation2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
- Rituximab/Bendamustine and Rituximab/Cytarabine (RB/RC) Induction Chemotherapy for Transplant-Eligible Patients with Mantle Cell Lymphoma: A Pooled Analysis of Two Pha...2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
- Clinical Aspects of Lymphoma/MyelomaHarvard Medical School - 1/1/2015
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Other
- Castleman's disease.Aster JC, Brown JR, Freedman AS, UpToDate; Basow DS (Ed)
Waltham, MA - 1/1/2014 - Overview of the pathobiology of the non-Hodgkin lymphomas.Brown JR, Freedman AS, Aster JC, UpToDate; Basow DS (Ed)
Waltham, MA - 1/1/2014 - Pathobiology of Burkitt lymphomas: Overview.Brown JR, Freedman AS, Aster JC, UpToDate; Basow DS (Ed)
Waltham, MA - 1/1/2014 - Join now to see all
Press Mentions
- High-Risk Follicular Lymphoma Subgroup IdentifiedAugust 24th, 2015
Grant Support
- CPG PLUS Rituximab Therapy In Follicular LymphomaNational Cancer Institute2004–2005
- Etanercept Therapy In Follicular LymphomaNational Cancer Institute2002–2003
- Integrin Signaling In Acute Lymphoblastic LeukemiaNational Cancer Institute1999–2001
- Translational Therapeutic Strategies For Low Grade LymphomaNational Cancer Institute1996–2001
- Germinal Center Interactions Of Normal/Malignant B CellsNational Cancer Institute1995–1998
- Germinal Center Adhesion Of Normal/Neoplastic B CellsNational Cancer Institute1991–1993
- NCI Physician-Investigator Development Award ProgramNational Cancer Institute1988–1990
- NCI Physician-Investigator Development Award ProgramNational Cancer Institute1986–1987
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