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Office
200 1st St Sw
Rochester, MN 55905Phone+1 507-284-2511
Education & Training
- University of Texas M.D. Anderson Cancer CenterFellowship, Leukemia, 2009 - 2010
- University of Oklahoma Health Sciences CenterFellowship, Hematology and Medical Oncology, 2006 - 2009
- Western Reserve Health Education/NEOMEDResidency, Internal Medicine, 2003 - 2006
- Damascus University Faculty of MedicineClass of 2000
Certifications & Licensure
- CT State Medical License 2017 - 2025
- MN State Medical License 2010 - 2025
- OK State Medical License 2006 - 2025
- TX State Medical License 2009 - 2012
- OH State Medical License 2002 - 2007
- American Board of Internal Medicine Hematology
Awards, Honors, & Recognition
- Kimberly Patterson Leukemia Research award UT MD Anderson Cancer Center, 2010
- Merit Award American Society of Hematology, 2009
- Internal Medicine Resident Top Educators Mayo Clinic, 2012
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Clinical Trials
- Efficacy and Safety of Oral Rigosertib in Transfusion-dependent, Low or Int-1 or Trisomy 8 Int-2 Myelodysplastic Syndrome Start of enrollment: 2012 May 01
- Daunorubicin Hydrochloride, Cytarabine, and Nilotinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2015 Mar 12
- Oral Rigosertib in Low Risk MDS Patients Refractory to ESAs Start of enrollment: 2013 Jul 01
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Publications & Presentations
PubMed
- 129 citationsRigosertib versus best supportive care for patients with high-risk myelodysplastic syndromes after failure of hypomethylating drugs (ONTIME): a randomised, controlled,...Guillermo Garcia-Manero, Pierre Fenaux, Aref Al-Kali, Maria R. Baer, Mikkael A. Sekeres
The Lancet. Oncology. 2016-04-01 - 1 citationsPHF6 mutations in chronic myelomonocytic leukemia identify a unique subset of patients with distinct phenotype and superior prognosis.Ayalew Tefferi, Saubia Fathima, Ali Khalid A Alsugair, Fnu Aperna, Anuya Natu
American Journal of Hematology. 2024-12-01 - 4 citationsTET2 somatic copy number alterations and allelic imbalances in chronic myelomonocytic leukemia.Mark Gurney, Patricia T Greipp, Troy Gliem, Ryan Knudson, Aref Al-Kali
Leukemia Research. 2023-11-01
Journal Articles
- Monosomal Karyotype Predicts Adverse Prognosis in Patients Diagnosed with Chronic Myelomonocytic Leukemia (CMML): A Single Institution ExperienceA Alsahlawi, H Alkhateeb, M Patnaik, K Begna, M Elliott, W Hogan, M Litzow, A Al-Kali, Clinical Lymphoma, Myeloma and Leukemia, 6/10/2014
- Toxoplasmosis in Patients with hematologic MalignanciesA Chintakuntlawar, M Kidd, A Al-Kali, W Wilson, CA Thompson, Leuk Lymphoma, 5/31/2014
- Revised Assessment of Response and Long-term Discontinuation Rates among 111 Patients with Myelofibrosis Treated with Momelotinib and RuxolitinibAbdelrahman RA, Begna KH, Al-Kali A, Hogan WJ, Litzow MR, Tefferi A, Leukemia, 1/1/2014
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Books/Book Chapters
Abstracts/Posters
- Pharmacokinetic Exposure Equivalence and Preliminary Efficacy and Safety from a Randomized Cross over Phase 3 Study (ASCERTAIN study) of an Oral Hypomethylating Agent ...Aref Al-Kali, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
- DNA Cytosine-Demethylating Agent 5-Aza-2'-Deoxycytidine Targets Leukemia Cells through Reducing DNA N6-MethyladenineAref Al-Kali, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
- Results of a Clinical Trial of H3B-8800, a Splicing Modulator, in Patients with Myelodysplastic Syndromes (MDS), Acute Myeloid Leukemia (AML) or Chronic Myelomonocytic...Aref Al-Kali, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
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Lectures
- A phase II study (NCI9775) of sapanisertib (MLN0128/TAK-228) in relapsed and/or refractory acute lymphoblastic leukemia (ALL): Interim analysis.2019 ASCO Annual Meeting - 6/1/2019
- A Phase II of Combination Daunorubicin and Cytarabine (Ara-c) and Nilotinib (TAsigna) (DATA) in Patients Newly Diagnosed with Acute Myeloid Leukemia and KIT Expression...2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
- Hematological Emergencies in the ICU8/19/2014
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Authored Content
- ASH 2018: The Current State of Myeloid MalignanciesDecember 2018
- ASH 2018: The Current State of Myeloid MalignanciesDecember 2018
Press Mentions
- Onconova Therapeutics to Present a Poster Session Relating to Intravenous Rigosertib at the 2017 American Society of Clinical Oncology Annual MeetingMay 22nd, 2017
- Ongoing AML Trials of Novel Agents Could Shift FieldMay 15th, 2017
Committees
- member, NCCN MDS committee 2016 - Present
Professional Memberships
- Member
- Member
- Member
Other Languages
- Arabic
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