AnthonyCharlesNicholsMD

PubMed

• 179 citations
  Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas
  Simon Papillon-Cavanagh, Chao Lu, Tenzin Gayden, Leonie G. Mikael, Denise Bechet
  Nature Genetics. 2017-02-01
• 106 citations
  Treatment-naïve HPV+ head and neck cancers display a T-cell-inflamed phenotype distinct from their HPV- counterparts that has implications for immunotherapy
  Steven F. Gameiro, Farhad Ghasemi, John W. Barrett, James Koropatnick, Anthony C. Nichols
  Oncoimmunology. 2018-07-30
• 14 citations
  Immune-based classification of HPV-associated oropharyngeal cancer with implications for biomarker-driven treatment de-intensification.
  Peter Y F Zeng, Matthew J Cecchini, John W Barrett, Matthew Shammas-Toma, Loris De Cecco
  Ebiomedicine. 2022-12-01

Journal Articles

• Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands  
  Weinreb I, Piscuoglio S, Martelotto LG, Waggott D, Ng CK, Perez-Ordonez B, Harding NJ, Alfaro J, Chu KC, Viale A, Fusco N, da Cruz Paula A, Marchio C, Sakr RA, Lim R, ..., Nature Genetics, 1/1/2014
• The control of anaplastic thyroid carcinoma cell lines by oncolytic poxviruses  
  Mundi N, Um S, Yoo J, Rizzo G, Black M, Pinto N, Palma DA, Fung K, MacNeil D, Mymryk JS, Barrett JW, Nichols AC, Virus Research, 1/1/2014
• Genomically driven precision medicine to improve outcomes in anaplastic thyroid cancer  
  Nicole Pinto, Morgan Black, Krupal Patel, John Yoo, Joe S Mymryk, John W Barrett, and Anthony Nichols, Journal of Oncology, 1/1/2014
• Defining the Genomic Landscape of Head and Neck Cancers Through Next-Generation Sequencing  
  Rizzo G, Black M, Mymryk JS, Barrett JW, Nichols AC, Oral Diseases, 1/1/2014
• The human papillomavirus E7 proteins associate with and alter p190RhoGAP function  
  Todorovic B, Nichols AC, Chitilian JM, Myers MP, Shepherd TG, Parsons SJ, Barrett JW, Banks L, Mymryk JS, Journal of Virology, 1/1/2014
• Variable expression of the forgotten oncogene E5 in HPV-positive oropharyngeal cancer  
  Um SH, Mundi N, Yoo J, Palma DA, Fung K, MacNeil D, Wehrli B, Mymryk JS, Barrett JW, Nichols AC, Journal of Clinical Virology, 1/1/2014
• Early-stage squamous cell carcinoma of the oropharynx: Radiotherapy vs TransOral Robotic Surgery (ORATOR) -- study protocol for a randomized phase II trial  
  Nichols AC, Yoo J, Hammond JA, Fung K, Winquist E, Read N, Venkatesan V, Macneil SD, Ernst DS, Kuruvilla S, Chen J, Corsten M, Odell M, Eapen L, Theurer J, Doyle PC, W..., BMC Cancer, 1/1/2013
• Does HPV type affect outcome in oropharyngeal cancer?  
  Nichols AC, Dhaliwal SS, Palma DA, Basmaji J, Chapeskie C, Dowthwaite S, Franklin JH, Fung K, Kwan K, Wehrli B, Howlett C, Siddiqui I, Salvadori MI, Winquist E, Ernst ..., Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 1/1/2013
• Development of a transoral robotic surgery program in Canada  
  Nichols AC, Fung K, Chapeskie C, Dowthwaite SA, Basmaji J, Dhaliwal S, Szeto CC, Palma DA, Theurer JA, Corsten MA, Odell M, Barrett JW, Franklin JH, Yoo J, Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 1/1/2013
• A Case Report and Genetic Characterization of a Massive Acinic Cell Carcinoma of the Parotid with Delayed Distant Metastases  
  Nichols AC, Chan-Seng-Yue M, Yoo J, Agrawal SK, Starmans MH, Waggott D, Harding NJ, Dowthwaite SA, Palma DA, Fung K, Wehrli B, Macneil SD, Lambin P, Winquist E, Koropa..., Case Reports in Oncological Medicine, 1/1/2013
• Transoral robotic total laryngectomy: Report of 3 cases  
  Dowthwaite S, Nichols AC, Yoo J, Smith RV, Dhaliwal S, Basmaji J, Franklin JH, Fung K, Head & Neck, 1/1/2013
• Viral Retasking of hBre1/RNF20 to Recruit hPaf1 for Transcriptional Activation  
  Fonseca GJ, Cohen MJ, Nichols AC, Barrett JW, Mymryk JS, PLoS Pathogens, 1/1/2013
• High Frequency of Activating PIK3CA Mutations in Human Papillomavirus-Positive Oropharyngeal Cancer  
  Nichols AC, Palma DA, Chow W, Tan S, Rajakumar C, Rizzo G, Fung K, Kwan K, Wehrli B, Winquist E, Koropatnick J, Mymryk JS, Yoo J, Barrett JW, JAMA Otolaryngol-Head & Neck Surgery, 1/1/2013
• The epidemic of human papillomavirus and oropharyngeal cancer in a Canadian population  
  Nichols AC, Palma DA, Dhaliwal SS, Tan S, Theuer J, Chow W, Rajakumar C, Um S, Mundi N, Berk S, Zhou R, Basmaji J, Rizzo G, Franklin JH, Fung K, Kwan K, Wehrli B, Salv..., Current Oncology, 1/1/2013
• Human papillomavirus in head and neck cancer  
  Palma DA, Nichols AC, Canadian Medical Association Journal, 1/1/2013
• Frequent Mutations in TP53 and CDKN2A Found by Next-Generation Sequencing of Head and Neck Cancer Cell Lines  
  Nichols AC, Yoo J, Palma DA, Fung K, Franklin JH, Koropatnick J, Mymryk JS, Batada NN, Barrett JW, Archives of otolaryngology-head & neck surgery, 1/1/2012
• The role of transoral robotic surgery in the management of oropharyngeal cancer: a review of the literature  
  Dowthwaite SA, Franklin JH, Palma DA, Fung K, Yoo J, Nichols AC, ISRN Oncology, 1/1/2012
• A Pilot Study Comparing HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas by Whole Exome Sequencing  
  Nichols AC, Chan-Seng-Yue M, Yoo J, Xu W, Dhaliwal S, Basmaji J, Szeto CC, Dowthwaite S, Todorovic B, Starmans MH, Lambin P, Palma DA, Fung K, Franklin JH, Wehrli B, K..., ISRN Oncology, 1/1/2012
• Detection of circulating tumor cells in advanced head and neck cancer using the cellsearch system  
  Nichols AC, Lowes LE, Szeto CC, Basmaji J, Dhaliwal S, Chapeskie C, Todorovic B, Read N, Venkatesan V, Hammond A, Palma DA, Winquist E, Ernst S, Fung K, Franklin JH, Y..., Head & Neck, 1/1/2011
• Bcl2 and human papilloma virus 16 as predictors of outcome following concurrent chemoradiation for advanced oropharyngeal cancer  
  Nichols AC, Finkelstein DM, Faquin WC, Westra WH, Mroz EA, Kneuertz P, Begum S, Michaud WA, Busse PM, Clark JR, Rocco JW, Clinical cancer research : an official journal of the American Association for Cancer Research, 1/1/2010
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Lectures

• Personalizing Care in Head and Neck Cancer. 
  Canada - 1/1/2014
• Targeting PIK3CA in Head and Neck Cancers with BYL719, An Alpha Specific PI3K Inhibitor. 
  Canada - 1/1/2014
• The Role of Transoral Surgery in Management of HPV-positive Oropharyngeal Cancer. 
  Canada - 1/1/2014
• Oncolytic Poxviruses for the Treatment of Head and Neck Cancer. 
  Toronto, Canada - 1/1/2012
• A review of HPV testing methods. 
  Toronto, Canada - 1/1/2012
• Integration of biomarkers into clinical trials. 
  Toronto, Canada - 1/1/2012
• The incidence of human papillomavirus related oropharyngeal cancer in Southwestern Ontario. 
  Victoria, Canada - 1/1/2011
• Ki-67 predicts radiation failure in early laryngeal cancer. 
  Victoria, Canada - 1/1/2011
• Development of a Transoral Robotic Surgery Program at the University of Western Ontario. 
  Victoria, Canada - 1/1/2011
• Circulating tumor cells in head and neck cancer. 
  Victoria, Canada - 1/1/2011
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