Anil KKRustgiMD

Gastroenterology • New York, NY

Esophagus Disease, Gastrointestinal Cancer, Pancreas Disease

Physician

Join to view full profile

Dr. Rustgi is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
Connect with colleagues in the same hospital or clinic.
Read the latest clinical news, personalized to your specialty.

See Dr. Rustgi's full profile

Already have an account?

Office
1130 Saint Nicholas Avenue
New York, NY 10032
Phone+1 212-851-4822

Summary

Dr. Anil K Rustgi is a gastroenterologist in New York, NY and is affiliated with NewYork-Presbyterian/Columbia University Irving Medical Center. He is the Director of the Herbert Irving Comprehensive Cancer Center-HICCC (NCI designated). He received his undergraduate degree from Yale University (Summa cum laude), medical degree from Duke University (AOA), internship/residency from Beth Israel Hospital/Harvard Medical School, and GI fellowship from Massachusetts General Hospital (MGH)/Harvard Medical School. He rose to Associate Professor of Medicine at MGH/Harvard, prior to recruitment as Chief of GI and T. Grier Miller Professor of Medicine at the University of Pennsylvania from 1998-2018. Since 2019, he is now Director of HICCC, Associate Dean of Oncology and Chief of Cancer Services at Columbia/NYP. He is past President of the American Gastroenterology Association and American Pancreas Association, as well as past Editor-in-Chief of Gastroenterology (the leading journal of the specialty). He has been elected to the ASCI, AAP, AAAS, American Cancer Society Professorship and the National Academy of Medicine. He has received multiple mentorship awards. He has received the AGA's Friedenwald medal and the Beaumont Prize. As a physician-scientist, he is funded through the NIH, ACS and SU2C. He has published more than 400 publications that are highly cited, and he has lectured at other universities and in national/international meetings. He practices hereditary GI cancer genetics.

Education & Training

Massachusetts General HospitalFellowship, Gastroenterology, 1987 - 1990
Beth Israel Deaconess Medical CenterResidency, Internal Medicine, 1984 - 1987
Duke University School of MedicineClass of 1984
Yale UniversityB.S., Summa Cum Laude, 1976 - 1980

Certifications & Licensure

NY State Medical License 2019 - 2026
PA State Medical License 1998 - 2024
MA State Medical License 1986 - 2001
American Board of Internal Medicine Internal Medicine

Awards, Honors, & Recognition

AGA Beaumont Prize 2023
Super Doctor SuperDoctors.com
National Academy ofMedicine 2019
American Association for the Advancement of Science 2017
AGA Friedenwald Medal 2017
The Ruth C. Brufsky Award for Excellence in Research in Pancreatic Cancer 2013
Research Mentor Award AGA Institute Council Gastrointestinal Oncology Section, 2013
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Arthur Asbury Outstanding Faculty Mentor Award University of Pennsylvania, 2012
Distinguished Mentor Award University of Pennsylvania Biomedical Postdoctoral Program (BPP), 2012
Distinguished Achievement Award South Asian American Society for Cancer Research at annual AACR meeting, 2012
Fellow (AGAF) American Gastroenterological Association, 2011
Research Professorship (competitive selection) American Cancer Society, 2009
Selected (approved by HHS Dept.) NIDDK Advisory Council, 2009
Elected American Association of Physicians, 2007
Elected American Society for Biochemistry and Molecular Biology, 2007
Faculty Award MD PhD students at the University of Pennsylvania, 2003
Top Docs in the United States 2001
Investigator Award Osler Society (Interurban Club), 1999
Elected American Society of Clinical Investigation, 1999
Elected Member The American Society for Clinical Investigation, 1999
Young Investigator Award for Research Achievement in Gastroenterology GRG/AGA, 1997
Jr. Faculty Research Award American Cancer Society, 1996
Funderberg Research Award in Gastric Cancer Biology American Gastroenterological Association (AGA), 1996
Fiterman Basic Science Research Award (Walter B. Cannon Award) American Gastroenterological Association (AGA), 1995
Clinical Investigator Award NIH, 1991
Fellowship American Cancer Society, 1991
Fellowship AID for Cancer, 1989
Fellowship American Gastroenterological Association (AGA), 1989
Winner for Clinical Study New England Endoscopy Society, 1987
Trent Prize in the History of Medicine Duke University Medical School, 1984
Davison Scholarship for Study of Infectious Diseases in Brazil Duke University Medical School, 1983
Master’s Service Award Yale University, 1980
Department Honors in Molecular Biophysics and Biochemistry Yale University, 1980
Join now to see all

Clinical Trials

The Cancer of the Pancreas Screening-5 CAPS5)Study Start of enrollment: 2014 Jan 06
Recruiting
Phase 3
Preliminary Evaluation of Septin9 in Patients With Hereditary Colon Cancer Syndromes Start of enrollment: 2014 Jul 01
Completed

Publications & Presentations

PubMed

362 citations
The genetics of hereditary colon cancer
Anil K. Rustgi
Genes & Development. 2007-10-15
483 citations
Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.
Daniel L. Worthley, Michael Churchill, Jocelyn T. Compton, Yagnesh Tailor, Meenakshi Rao
Cell. 2015-01-15
317 citations
Myeloid derived suppressor cells: Targets for therapy
Todd J. Waldron, Jon G. Quatromoni, Tatiana A. Karakasheva, Sunil Singhal, Anil K. Rustgi
Oncoimmunology. 2013-04-01

Journal Articles

Gastroesophageal reflux disease and cancers of the esophagus and gastroesophageal junction
Katzka D, Rustgi AK, Medical Clinics of North America
IMP1 3’ UTR Shortening Enhances Metastatic Burden in Colorectal Cancer
Anil Rustgi, MD, Carcinogenesis
Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems
Hartman KG, Bortner JD, Falk GW, Yu J, Martin MG, Rustgi AK, Lynch JP, Stem Cell Research & Therapy, 12/1/2013
EGFR Inhibition Promotes an Aggressive Invasion Pattern Mediated by Mesenchymal-like Tumor Cells within Squamous Cell Carcinomas
Basu D, Bewley AF, Sperry SM, Montone KT, Gimotty PA, Rasanen K, Facompre ND, Weinstein GS, Nakagawa H, Diehl JA, Rustgi AK, Herlyn M, Molecular Cancer Therapeutics, 8/12/2013
BRAF: a drivers of the serrated pathway in colon cancer
Rustgi AK, Cancer Cell, 7/8/2013
IMP1 promotes tumor growth, dissemination, and a tumor-initiating cell phenotype in colorectal cancer cell xenografts
Hamilton KE, Noubissi FK, Katti PS, Hahn CM, Davey SR, Lundsmith ET, Klein-Szanto AJ, Rhim AD, Spiegelman VS, Rustgi AK, Carcinogenesis, 6/12/2013
Imbalance of desmoplastic stromal cell numbers drives aggressive cancer processes
Kadaba R, Birke H, Wang J, Hooper S, Andl CD, Maggio FD, Soylu E, Ghallab M, Bor D, Froeling FE, Bhattacharya S, Rustgi AK, Sahai E, Chelala C, Sasieni P, Kocher HM, J Pathol, 1/28/2013
Matricellular proteins: priming the tumour microenvironment for cancer development and metastasis
Wong GS, Rustgi AK, Br J Cancer, 1/15/2013
The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis
Reichert M, Takano S, von Burstin J, Kim SB, Lee JS, Ihida-Stansbury K, Hahn C, Heeg S, Schneider G, Rhim AD, Stanger BZ, Rustgi AK, Genes Dev, 1/1/2013
A common p53 mutation (R175H) activates c-Met receptor tyrosine kinase to enhance tumor cell invasion
Grugan KD, Vega ME, Wong GS, Diehl JA, Bass AJ, Wong KK, Nakagawa H, Rustgi AK, Cancer Biol Ther, 1/1/2013
Isolation, culture and genetic manipulation of mouse pancreatic ductal cells
Reichert M, Takano S, Heeg S, Bakir B, Botta GP, Rustgi AK, Nature Protocols, 1/1/2013
Myeloid derived suppressor cells: Targets for therapy
Waldron TJ, Quatromoni JG, Karakasheva TA, Singhal S, Rustgi AK, Oncoimmunology, 1/1/2013
Development and characterization of an organotypic model of Barrett's esophagus
Kosoff RE, Gardiner KL, Merlo LM, Pavlov K, Rustgi AK, Maley CC, Journal of Cellular Physiology, 1/1/2012
Inflammation and bile acids induce stem cell migration and differentation in a novel mouse model of Barrett's esophagus
Quante M, Bhagat G, Abrams J, Marache F, Good P, Lee MD, Friedman R, Asfaha S, Dubeykovskaya Z, Mahmood U, Figueredo JL, Kitajewski J, Shawber C, Lightdale C, Rustgi A..., Cancer Cell, 1/1/2012
Isolation and characterization of mouse and human esophageal epithelial cells in 3D organotypic culture
Kalabis J, Wong G, Vega ME, Natsuizaka M, Robertson ES, Herlyn M, Nakagawa H, Rustgi AK, Nature Protocols, 1/1/2012
EMT and dissemination precede pancreatic tumor formation
Rhim AD, Mirek ET, Aiello N, Maitra A, Beatty GL, Bailey JM, Reichert M, Rustgi AK, Vonderheide RH, Leach SD, Stanger BZ, Cell, 1/1/2012
Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia
Quante M, Bhagat G, Abrams JA, Marache F, Good P, Lee MD, Lee Y, Friedman R, Asfaha S, Dubeykovskaya Z, Mahmood U, Figueiredo JL, Kitajewski J, Shawber C, Lightdale CJ..., Cancer Cell, 1/1/2012
Silencing of IkBBeta mRNA causes disruption of mitochondrial retrograde signaling and suppression of tumor growth in vivo
Tang W, Chowdhury AR, Guha M, Huang L, Winkle TV, Rustgi AK, Avadhani NG, Carcinogenesis, 1/1/2012
A LIN28B polymorphism predicts for colon cancer survival
Ye Y, Madison BB, Wu X, Rustgi AK, Cancer Biology and Ther, 1/1/2012
Identification of Lynch syndrome among patients with colorectal cancer
Moreira L, Balaguer F, Lindor N, de la Chapelle A, Hampel H, Aaltonen LA, Hopper JL, Le Marchand L, Gallinger S, Newcomb PA, Haile R, Thibodeau SN, Gunawardena S, Jenk..., JAMA, 1/1/2012
IMP-1 displays crosstalk with K-Ras and modulates colon cancer cell survival through the novel pro-apoptotic protein CYFIP2
Mongroo PS, Noubissi FK, Cuatrecasas M, Kalabis J, King CE, Johnstone CN, Bowser MJ, Castells A, Spiegelman VS, Rustgi AK, Cancer Res, 1/1/2011
Adult pancreatic acinar cells dedifferentiate to an embryonic progenitor phenotype with concomitant activation of a senescence program that is present in chronic pancr...
Pinho AV, Rooman I, Reichert M, De Medts N, Bouwens L, Rustgi AK, Real FX, Gut, 1/1/2011
Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a bona fide tumor suppressor gene
Stairs DB, Bayne LJ, Rhoades B, Vega ME, Kalabis J, Klein-Szanto A, Lee JS, Katz JP, Diehl JA, Vonderheide RH, Reynolds AB, Rustgi AK, Cancer Cell, 1/1/2011
Systemic activation of K-ras rapidly induces gastric hyperplasia and metaplasia in mice
Matkar SS, Durham A, Brice A, Wang TC, Rustgi AK, Hua X, American Journal of Clinical Research, 1/1/2011
LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms
King CE, Wang L, Winograd R, Madison BB, Mongroo PS, Johnstone CN, Rustgi AK, Oncogene, 1/1/2011
Join now to see all

Press Mentions

Dr. Lewis Silverman to Lead Pediatric Hematology, Oncology and Stem Cell Transplantation at NewYork-Presbyterian Morgan Stanley Children’s Hospital and Columbia UniversityAugust 29th, 2024
CUIMC Facts and FiguresJanuary 25th, 2021
At Elite Medical Centers, Even Workers Who Don’t Qualify Are VaccinatedJanuary 10th, 2021
Join now to see all

Grant Support

Stem Cells And The Origins Of Barrett'S EsophagusNational Cancer Institute2011
The Intestinal Stem Cell NicheNational Institute Of Diabetes And Digestive And Kidney Diseases2009–2011
Transformed Epithelial Cells And Activated Fibroblasts In The Esopheageal Tumor MNational Cancer Institute2009–2011
Inflammation And The Esophageal Tumor MicroenvironmentNational Cancer Institute2009–2011
Administrative CoreNational Cancer Institute2009–2011
Micrornas And Chromosome 22q In The ColonNational Institute Of Diabetes And Digestive And Kidney Diseases2008–2011
The Molecular Regulation Of Pancratic Ductal Epithelial MorphogenesisNational Institute Of Diabetes And Digestive And Kidney Diseases2007–2011
Mechanisms Of Esophageal CarcinogenesisNational Cancer Institute2003–2011
Center For Digestive And Liver DiseasesNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2011
Training Program In Gastrointestinal SciencesNational Institute Of Diabetes And Digestive And Kidney Diseases1999–2011
Chromosome 22q Genetic Studies In The ColonNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2008
Keratin 19 And Pancreatic Ductal BiologyNational Institute Of Diabetes And Digestive And Kidney Diseases2002–2006
Cyclin D1 And Genetic Model Of Oral CarcinogenesisNational Institute Of Dental &Craniofacial Research2002
Regulation Of Esophageal Epithelial Gene ExpressionNational Institute Of Diabetes And Digestive And Kidney Diseases1998–2001
Cyclin D1 And Genetic Model Of Oral CarcinogenesisNational Institute Of Dental &Craniofacial Research1998–2001
Regulation Of Esophageal Epithelial Gene ExpressionNational Institute Of Diabetes And Digestive And Kidney Diseases1998
Myc-Oncogenes In Neuroblastoma And Colon CancerNational Cancer Institute1991–1994