AndrewXiuxaunZhuMD

Oncology • Boston, MA

Associate Professor of Medicine, Massachusetts General Hospital

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Office
55 Fruit St
Yawkey 7e
Boston, MA 02114
Phone+1 617-724-6193

Fax+1 617-724-1137

Education & Training

Memorial Sloan Kettering Cancer CenterFellowship, Hematology and Medical Oncology, 1997 - 2000
Yale-New Haven Medical CenterResidency, Internal Medicine, 1995 - 1997
University of MinnesotaInternship, Internal Medicine, 1994 - 1995
Beijing Medical UniversityClass of 1982

Certifications & Licensure

MA State Medical License 2000 - 2025

Clinical Trials

Epirubicin and Thalidomide in Treating Patients With Liver Cancer Start of enrollment: 2001 Dec 01
Completed
Phase 2
Cetuximab in Patients With Unresectable or Metastatic Hepatocellular Carcinoma Start of enrollment: 2005 Jan 01
Completed
Phase 2
Gemcitabine, Oxaliplatin in Combination With Bevacizumab in Patients With Hepatocellular Carcinoma Start of enrollment: 2004 Apr 01
Completed
Phase 2
Capecitabine, Oxaliplatin, Bevacizumab and Radiation Therapy in Patients With Biliary Tract and Gallbladder Cancer Start of enrollment: 2004 Dec 01
Completed
Phase 2
Gemcitabine, Oxaliplatin in Combination With Bevacizumab in Biliary Tract and Gallbladder Cancer Start of enrollment: 2006 May 01
Completed
Phase 2
SU011248 in Combination With Irinotecan and Cetuximab as a Second Line Regimen for Stage IV Colorectal Cancer Start of enrollment: 2006 Jul 01
Terminated
Phase 1, Phase 2
SU011248 in Advanced Hepatocellular Carcinoma Start of enrollment: 2006 Apr 01
Completed
Phase 2
AZD2171 in Treating Patients With Locally Advanced Unresectable or Metastatic Liver Cancer Start of enrollment: 2009 May 01
Terminated
Phase 2
RAD001 in Advanced Hepatocellular Carcinoma Start of enrollment: 2007 Aug 01
Completed
Phase 1, Phase 2
Sorafenib + mFOLFOX for Hepatocellular Carcinoma Start of enrollment: 2013 Jan 01
Completed
Phase 2
HCV-RNA Kinetics During Sorafenib for Hepatocellular Carcinoma (HCC) Start of enrollment: 2013 May 01
Terminated
Phase 4
Dose Escalation Study of OMP-54F28 in Combination With Sorafenib in Patients With Hepatocellular Cancer Start of enrollment: 2014 Jan 01
Completed
Phase 1
A Phase II, Single Arm Study of BGJ398 in Patients With Advanced Cholangiocarcinoma Start of enrollment: 2014 Jul 23
Terminated
Phase 2
Phase II Trial of Dasatinib in Patients With Isocitrate Dehydrogenase (IDH)-Mutant Advanced Intrahepatic Cholangiocarcinoma Start of enrollment: 2015 Apr 01
Completed
Phase 2
A Study of Ramucirumab (LY3009806) Versus Placebo in Participants With Hepatocellular Carcinoma and Elevated Baseline Alpha-Fetoprotein Start of enrollment: 2015 Jul 20
Completed
Phase 3
National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer Start of enrollment: 2021 Jul 28
Recruiting
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Publications & Presentations

PubMed

A Case study of polypharmacy-induced serotonin syndrome in a cancer patient.
Andrew Zhu, Nicole Kuhnly, Leon Chen, Alina O Dulu
Journal of the American Association of Nurse Practitioners. 2024-12-01
Pharmacokinetics/pharmacodynamics of ivosidenib in advanced IDH1-mutant cholangiocarcinoma: findings from the phase III ClarIDHy study.
Bin Fan, Ghassan K Abou-Alfa, Andrew X Zhu, Shuchi S Pandya, Hongxia Jia
Cancer Chemotherapy and Pharmacology. 2024-05-01
12 citations
Cabozantinib plus atezolizumab versus sorafenib for advanced hepatocellular carcinoma (COSMIC-312): final results of a randomised phase 3 study.
Thomas Yau, Ahmed Kaseb, Ann-Lii Cheng, Shukui Qin, Andrew X Zhu
The Lancet. Gastroenterology & Hepatology. 2024-04-01

Journal Articles

Augmenting Anticancer Immunity Through Combined Targeting of Angiogenic and PD-1/PD-L1 Pathways: Challenges and Opportunities
Andrew Zhu, MD, Frontiers in Immunology
A Phase II and Biomarker Study of Sorafenib Combined with FOLFOX in Patients with Advanced Hepatocellular Carcinoma (HCC)
Hui Zheng, Rakesh K Jain, Lipika Goyal, Andrew X Zhu, Clinical Cancer Research

Lectures

REACH-2: A randomized, double-blind, placebo-controlled phase 3 study of ramucirumab versus placebo as second-line treatment in patients with advanced hepatocellular c...
2018 ASCO Annual Meeting - Chicago, Illinois - 06/4/2018
Pembrolizumab (pembro) in patients with advanced hepatocellular carcinoma (HCC): KEYNOTE-224 update.
2018 ASCO Annual Meeting - Chicago, Illinois - 06/3/2018

Press Mentions

Proprietary SARS-CoV-2 3CL Inhibitor Rapidly Progressing in Clinical Trials, Market Approval of Trilaciclib Expected in China, Simcere Reveals Global Innovation Ambition on R&D DayApril 19th, 2022
I-mab Announces Multiple Presentations at the 2022 American Association for Cancer Research (AACR) Annual MeetingMarch 9th, 2022
I-mab Receives FDA Orphan Drug Designation for Its Novel Claudin 18.2 X 4-1BB Bispecific Antibody TJ-CD4B for the Treatment of Gastric CancerMarch 3rd, 2022
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Professional Memberships

American Society of Clinical Oncology - ASCO
Member