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Office
6520 MSRB I SPC 5682
1150 W Medical Center Drive
Ann Arbor, MI 48109
Summary
- I am an Associate Professor of Internal Medicine and Microbiology & Immunology at the University of Michigan as well as a Staff Physician at the Ann Arbor VA Healthcare System. I attended Harvard College for my undergraduate studies, the Tri-Institutional MD-PhD program in New York, an internal medicine residency at the Brigham and Women’s Hospital, and then a clinical and research fellowship in gastroenterology and hepatology at the Massachusetts General Hospital.
My laboratory research focuses on the cell biology of RNA virus infection, originally hepatitis C virus and more recently dengue, Zika, and SARS-CoV-2. I am currently serving my second term on the AASLD Research Awards Committee and am an elected member of the American Society for Clinical Investigation.
My clinical practice is primarily at the VA Ann Arbor Healthcare System, where I direct the multidisciplinary liver tumor board and care for veterans with a variety of liver disorders or with primary liver cancer.
From a teaching standpoint, I am the Assistant Dean for Early Medical Education, overseeing University of Michigan Medical School's preclinical curriculum. I have won multiple institutional awards for undergraduate and graduate medical education.
Education & Training
- Massachusetts General HospitalFellowship, Gastroenterology, 2005 - 2009
- Brigham and Women's HospitalResidency, Internal Medicine, 2002 - 2005
- Weill Cornell MedicineClass of 2002
- Weill Cornell Graduate School of Medical SciencesPhD, Cell Biology and Genetics, 1994 - 2001
Certifications & Licensure
- MI State Medical License 2009 - 2025
- MA State Medical License 2004 - 2011
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Gastroenterology
Awards, Honors, & Recognition
- Elected member American Society for Clinical Investigation, 2023
- Fellow American Association for the Study of Liver Diseases (AASLD), 2023
- Kaiser Permanente Award for Excellence in Teaching University of Michigan Medical School, 2021
- Join now to see all
Publications & Presentations
PubMed
- 107 citationsRab18 binds to hepatitis C virus NS5A and promotes interaction between sites of viral replication and lipid dropletsShadi Salloum, Hongliang Wang, Charles Ferguson, Robert G. Parton, Andrew W. Tai
Plos Pathogens. 2013-08-01 - 15 citationsAmilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structuresMartina Zafferani, Christina Haddad, Le Luo, Jesse Davila-Calderon, Liang Yuan-Chiu
Biorxiv. 2020-12-06 - 14 citationsReticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication.Jeffrey M Williams, Yu-Jie Chen, Woo Jung Cho, Andrew W Tai, Billy Tsai
The Journal of Cell Biology. 2023-07-03
Other
- Investigational therapies for hepatitis C virus infectionTai AW, Chung RT
http://www.uptodate.com/contents/investigational-therapies-for-hepatitis-c-virus-infection
UpToDate, Wolters Kluwer Health - 2013-04-05 - Studies of telaprevir and boceprevir in the treatment of chronic hepatitis C virus genotype 1Tai AW, Chung RT
http://www.uptodate.com/contents/studies-of-telaprevir-and-boceprevir-in-the-treatment-of-chronic-he
UpToDate, Wolters Kluwer Health - 2012-10-05
Press Mentions
- Ann Arbor Medical and Mental Health Doctors Want Date for in-Person School Learning OptionFebruary 8th, 2021
- Study Identifies Human Genes Required for Hepatitis C Viral ReplicationMarch 18th, 2009
Grant Support
- How flaviviruses hijack a host transmembrane protein chaperone to promote viral infectionNIH/NIGMS2021–2025
- HIV-1 Genomic RNA IntegrityNIH/NIAID2020–2022
- Mechanisms of encapsidated HIV-1 RNA modificationCenter for HIV RNA Studies2019–2021
- Subversion of hepatocyte phosphoinositide metabolism by hepatitis C virusNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2013–2018
- Characterization Of A Host Hepatocyte Factor That Regulates HCV ReplicationNational Institute Of Allergy And Infectious Diseases2010–2011
- Whole-Genome Sirna Screen For Host Genes Supporting Hepatitis C Virus ReplicationNational Institute Of Allergy And Infectious Diseases2008
Committees
- Member, Research Awards Committee, American Association for the Study of Liver Diseases 2023 - Present
- Member, Research Awards Committee, American Association for the Study of Liver Diseases 2018 - 2020
Research History
- Research Fellow in GastroenterologyLaboratory of Raymond T. Chung at Massachusetts General Hospital, Boston, MA2006 - 2009
Professional Memberships
- Member
- Member
- American Association for the Study of Liver Diseases (AASLD)Fellow
- American Society for Virology (ASV)Member
- Member
- American Society for Clinical InvestigationMember
External Links
- Lab websitehttp://www.med.umich.edu/tailab/
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