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Office
3601 5th Ave
# Falk
Pittsburgh, PA 15213Phone+1 412-383-8700
Education & Training
- Icahn School of Medicine at Mount Sinai/Morningside/WestResidency, Internal Medicine, 1974 - 1977
- Columbia University Vagelos College of Physicians and SurgeonsClass of 1974
- Trinity CollegeB.S., 1966 - 1970
Certifications & Licensure
- LA State Medical License 1980 - 2018
- PA State Medical License 1997 - 2012
Awards, Honors, & Recognition
- Harold Rifkin Visiting Professorship Albert Einstein College of Medicine, 2014
- Ray Kroc Scientific Award University of Uppsala Diabetes Center, 2014
- Invited Symposium Speaker Keystone Meeting, Keystone CO, 2014
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Clinical Trials
- PTHrP and Osteoporosis Start of enrollment: 1999 Jun 01
- Longitudinal Lactation Bone Density Study Start of enrollment: 2012 Aug 01
Publications & Presentations
PubMed
- 94 citationsDisruption of Hepatocyte Growth Factor/c-Met Signaling Enhances Pancreatic β-Cell Death and Accelerates the Onset of DiabetesJosé Manuel Mellado-Gil, Taylor C. Rosa, Cem Demirci, Jose A. Gonzalez-Pertusa, Silvia Velazquez-Garcia
Diabetes. 2011-02-01 - 24 citationsA novel role for the actin-binding protein drebrin in regulating opiate addiction.Jennifer A. Martin, Craig T. Werner, Swarup Mitra, Ping Zhong, Zi-Jun Wang
Nature Communications. 2019-09-12 - 290 citationsHumoral hypercalcemia of cancer. Identification of a novel parathyroid hormone-like peptide.Arthur E. Broadus, Marguerite Mangin, Kyoji Ikeda, Karl L. Insogna, Eleanor C. Weir
The New England Journal of Medicine. 1988-09-01
Journal Articles
- Human pancreatic Beta-cell lncRNAs control cell-specific regulatory networksAkerman I, Tu Z, Beucher A, Rolando DMY, Sauty-Colace C, Benzara M, Nakic N, Yang J, Wang H, Pasquali L, Moran I, Garcia-Hurtado J, Castro N, Gonzalez R, Stewart AF, B..., Cell Metabolism, 1/1/2017
- Beta-trophin vs Bitter-trophin and the Elephant in the Room: Time for a New Normal in Beta Cell Regeneration ResearchStewart AF, Diabetes, 1/1/2014
- Overexpression of hepatocyte nuclear factor 4alpha initiates cell cycle entry, but it not sufficient to promote Beta-cell expansion in human isletsRieck S, Li Z, Sandhu AK, Liu C, Naji Al, Takane KK, Fiaschi-Taesch NM, Stewart AF, Kushner JA, Kaestner KH, Mol Endocrinol, 1/1/2012
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Books/Book Chapters
Lectures
- "Insulinoma Data Mining for Beta Cell Regenerative Drug Discovery."Orlando, FL - 1/30/2017
- "Advances in Human Beta Cell Regeneration for Diabetes."Medical College of Georgia, Augusta, GA - 1/3/2017
- "Strategies for Induction of Human Beta Cell Expansion for Diabetes."University of Pennsylvania School of Medicine, Philadelphia PA - 1/27/2016
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Other
- Parathyroid hormone-related protein: physiology and pathophysiology.Stewart AF, Procedimientos de le Sociedad Espanola de la Investigacion Osea y Metabolismo Mineral
Granada, Spain - 1/1/1998 - Purification and molecular cloning of a novel parathyroid hormone-like protein responsible for humoral hypercalcemia of malignancy.Stewart AF, Burtis WJ, Mangin M, Ikeda K, Insogna KL, Broadus AE, Cancer Cells, Cold Spring Harbor Proceedings, pp. 339-342
1/1/1989
Press Mentions
- Revolutionary New Diabetes Drug Multiplies Insulin-Producing Cells by 700%September 24th, 2024
- Groundbreaking Diabetes Drug Multiplies Insulin-Producing Cells by 700%August 24th, 2024
- Breakthrough Diabetes Drug Multiplies Insulin-Producing Cells by 700%July 23rd, 2024
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Grant Support
- Pathophysiology Of Pth-Related Protein (1-36) In HumansNational Institute Of Diabetes And Digestive And Kidney Diseases2001–2012
- Multi-Disciplinary Approaches To Driving Therapeutic Human Beta Cell ReplicationNational Institute Of Diabetes And Digestive And Kidney Diseases2010–2011
- Research Training In Diabetes And EndocrinologyNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2011
- Islet Growth Factors Transgenic And Viral ModelingNational Institute Of Diabetes And Digestive And Kidney Diseases2006–2010
- Modeling Bone Formation And 1,25 Vitamin D In Humoral Hypercalcemia Of MalignancyNational Institute Of Diabetes And Digestive And Kidney Diseases2009
- Modeling Bone Formation &1,25 Vitamin D In Humoral Hypercalcemia Of MalignancyNational Institute Of Diabetes And Digestive And Kidney Diseases2007–2008
- Modeling Bone Formation And 125 Vitamin D In Humoral Hypercalcemia Of MalignancyNational Institute Of Diabetes And Digestive And Kidney Diseases2006
- Islet Allograft Gene Therapy For Primate DiabetesNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2005
- Anabolic Skeletal Agents For OsteoporosisNational Institute Of Diabetes And Digestive And Kidney Diseases2004
- Renal Calcium Handling &1, 25 Vitamin D SynthesisNational Center For Research Resources2004
- Secretion Of Parathyroid Hormone And PthrpNational Center For Research Resources2000–2002
- 1,25 Vitamin D Synthesis--Pthrp In Malign HypercalcemiaNational Center For Research Resources2000–2002
- 1,25 Vitamin D Synthesis In Response To PTH &PthrNational Center For Research Resources2000–2002
- PTH Related Protein--Nuclear Targeting And MitogenesisNational Institute Of Diabetes And Digestive And Kidney Diseases1999–2002
- Pth-Related Protein In The Pancreatic IsletNational Institute Of Diabetes And Digestive And Kidney Diseases1998–2002
- Islet Growth Factors--Transgenic And Viral ModelingNational Institute Of Diabetes And Digestive And Kidney Diseases1998–2001
- Two Week Study Of Human Phtrp(1-36) Injection On Mineral HomeostasisNational Center For Research Resources1998–1999
- Pathophysiology Of Pth-Related Protein (1-36)National Institute Of Diabetes And Digestive And Kidney Diseases1997–1999
- Subcutaneous Administration Of Human PTH Related ProteinNational Center For Research Resources1996–1999
- Pathophysiology Of Pth-Related Protein (1-36)National Institute Of Diabetes And Digestive And Kidney Diseases1996–1997
- Pth-Related Protein In The Pancreatic IsletNational Institute Of Diabetes And Digestive And Kidney Diseases1995–1997
- Metabolic Clearance Rate And Dose Response Of Human Pthrp (1-36)National Center For Research Resources1996
- Human Parathyroid Hormone Infusion StudiesNational Center For Research Resources1996
- Malignancy Associated HypercalcemiaNational Center For Research Resources1985
- Calcium Metabolism In Immobilized SubjectsNational Center For Research Resources1985
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