AndrewAlanNierenbergMD

Thomas P. Hackett, MD, Endowed Chair in Psychiatry at MGH, Director, Dauten Family Center for Bipolar Treatment Innovation, Associate Director, Depression Clinical and Research Program, Co-director, Center for Clinical Research Education, Division of Clinical Research, Massachusetts General Hospital, Professor of Psychiatry, Harvard Medical School

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Office
50 Staniford St
Suite 580
Boston, MA 02114
Phone+1 617-724-0837

Fax+1 617-726-6768

Summary

Dr. Andrew Nierenberg is a psychiatrist in Boston, MA and is affiliated with Massachusetts General Hospital. He received his medical degree from Albert Einstein College of Medicine of Yeshiva University and has been in practice 37 years. He is experienced in depression, bipolar disorders , and psychopharmacology. He has more than 600 publications and over 35000 citings.

Education & Training

NYU Grossman School of MedicineResidency, Psychiatry, 1980 - 1984
Albert Einstein College of MedicineClass of 1980

Certifications & Licensure

MA State Medical License 1986 - 2025
American Board of Psychiatry and Neurology Psychiatry

Clinical Trials

Drug Therapy to Treat Minor Depression Start of enrollment: 2003 Feb 01
Completed
Not Applicable
Memantine and Cognitive Dysfunction in Bipolar Disorder Start of enrollment: 2005 Nov 01
Completed
Phase 4
Efficacy and Safety Study of a Combination Product [Drug:BCI-024 (Buspirone) and Drug:BCI-049 (Melatonin)] to Treat Major Depressive Disorder (MDD) Start of enrollment: 2008 May 01
Completed
Phase 2
Open Label Extension Assessing the Tolerability of BCI-024 in Combination With BCI-049 in Patients With Major Depressive Disorder (MDD) Start of enrollment: 2008 Jul 01
Completed
Phase 2
Comparative Effectiveness Study for Bipolar Disorder Start of enrollment: 2010 Sep 01
Completed
Phase 4
Exploring Biomarkers for Depression Start of enrollment: 2011 Aug 01
Completed
Complex Dynamic Systems in Mood Disorders Start of enrollment: 2011 Nov 01
Completed
Pattern Separation, Brain Derived Neurotrophic Factors, and Mechanisms of Vortioxetine Start of enrollment: 2017 Aug 24
Terminated
Phase 4
Sequential Therapy for the Treatment of Severe Bipolar Depression. Start of enrollment: 2018 Jan 15
Completed
Phase 2
Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder Start of enrollment: 2019 Dec 05
Recruiting
Early Phase 1
Healthy Mind Healthy You: A Study of Mindfulness Start of enrollment: 2019 Feb 27
Completed
Not Applicable
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Publications & Presentations

PubMed

Efficacy and safety of lemborexant in subjects with insomnia disorder receiving medications for depression or anxiety symptoms.
Andrew Krystal, Pierre Blier, Larry Culpepper, Andrew A Nierenberg, Yoshikazu Takaesu
Neuropsychopharmacology Reports. 2025-03-01
Pharmacotherapy in Comorbid Bipolar Disorder and Post-Traumatic Stress Disorder From the STEP-BD Cohort.
Samantha E Russell, Anna L Wrobel, David R Skvarc, Mojtaba Lotfaliany, Olivia M Dean
Bipolar Disorders. 2025-02-14
Neurobiological Mechanisms Link Bipolar Disorder to Cardiovascular Disease: A Retrospective Biobank Study of Adverse Event Risk and Contributory Mechanisms.
Ji Hyun Baek, Simran S Grewal, Krystel Abi Karam, Erin R Hanlon, Shady Abohashem
Bipolar Disorders. 2025-01-30

Journal Articles

Research Paper Tachyphylaxis in Major Depressive Disorder: A Review of the Current State of Research
Gustavo Kinrys, Andrew A Nierenberg, George I Papakostas, David Mischoulon, Maurizio Fava, Marlene P Freeman, ScienceDirect

Authored Content

Peroxisome Proliferator Activated Receptor Gamma Co-Activator-1 Alpha as a Novel Target for Bipolar Disorder and Other Neuropsychiatric DisordersJanuary 2018

Press Mentions

Underfunded, Underdiagnosed, and Misunderstood: What’s Next for Bipolar DisorderFebruary 11th, 2025
Myriad Genetics Research Shows Reduction in Hospitalizations for Patients with Depression After GeneSight TestingApril 9th, 2024
NRx Pharmaceuticals, Inc. (NASDAQ:NRXP) Q4 2022 Earnings Call TranscriptApril 5th, 2023
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Grant Support

Comparative Effectiveness Study For Bipolar DisorderAgency For Healthcare Research And Quality2010
Pharmacotherapy For Minor DepressionNational Institute Of Mental Health2001–2004
Course Of Treatment Resistant DepressionNational Center For Research Resources1996–1999
Course Of Treatment Resistant DepressionNational Institute Of Mental Health1993–1996
The Course Of Treatment Resistant DepressionNational Institute Of Mental Health1992
Course Of Treatment Resistant DepressionNational Institute Of Mental Health1992