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Andrew Krivoshik, MD, Pediatrics, Boston, MA

AndrewPeterKrivoshikMDPhD

Pediatrics Boston, MA

Pediatric Hematology/Oncology

President and Head of Development, Astellas Pharma Global Development

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  • Office

    451 D Street
    Boston, MA 02210

Summary

  • Andrew Krivoshik, MD, PhD is a senior pharmaceutical executive with success in leading global multidisciplinary cross functional teams. Dr. Krivoshik and his development teams have successfully submitted BLA and NDA global submissions leading to the global approvals of new medicines. He is licensed both as a physician, and as a professional engineer, in multiple jurisdictions and has served as an invited speaker and session chair at international scientific congresses.

Education & Training

  • Duke University Hospital
    Duke University HospitalFellowship, Pediatric Hematology/Oncology, 2002 - 2004
  • Mayo Clinic College of Medicine and Science (Rochester)
    Mayo Clinic College of Medicine and Science (Rochester)Residency, Pediatrics, 2000 - 2002
  • University of Illinois at Urbana-Champaign
    University of Illinois at Urbana-ChampaignPhD, Biophysics and Computational Biology, 1990 - 2001
  • Mayo Clinic College of Medicine and Science (Rochester)
    Mayo Clinic College of Medicine and Science (Rochester)Internship, Pediatrics, 1999 - 2000
  • University of Illinois College of Medicine
    University of Illinois College of MedicineClass of 1999, MD
  • Princeton University
    Princeton UniversityBSE, Electrical Engineering, Honors, 1986 - 1990

Certifications & Licensure

  • MI State Medical License
    MI State Medical License 2017 - 2027
  • IL State Medical License
    IL State Medical License 2004 - 2026
  • MA State Medical License
    MA State Medical License 2023 - 2026
  • MN State Medical License
    MN State Medical License 2000 - 2025
  • NC State Medical License
    NC State Medical License 2002 - 2025
  • WI State Medical License
    WI State Medical License 2018 - 2025
  • PA State Medical License
    PA State Medical License 2004 - 2007
  • American Board of Pediatrics Pediatrics

Awards, Honors, & Recognition

  • Recipient of Global Medical & Development award for Operational Excellence through the Astellas Way Global Recognition Program 2014 Astellas, 2014
  • Recipient of APGD-LT Award 2013 Special Recognition as member of the data flow optimization project team Astellas, 2013
  • Recipient of GPRD President’s Award for contribution to the successful phase 1 evaluation of a stabilized lipid formulation of ABT-263 in healthy volunteers Abbott Labs, 2010
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Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Enzalutamide in Men with Nonmetastatic Castration-Resistant Prostate Cancer  
    Hussain, M., K. Fizazi, F. Saad, P. Rathenborg, N. Shore, U. Ferreira, P. Ivashchenko, E. Demirhan, K. Modelska, D. Phung, A. Krivoshik, C. Sternberg, NEJM 378(26):2465-2474, 2018
  • Wilms’ tumor and neuroblastoma  
    Morgenstern, B, A. Krivoshik, V. Rodriguez, P. Anderson, Acta Paediatrica Suppl 445:78-85, 2004
  • Force relaxes before the fall of cytosolic calcium in the photomechanical response of rat sphincter pupillae  
    Krivoshik, A., L. Barr, Am J Physiol (Cell) 279:C274, 2000

Other

  • The role of calcium in signal transduction: Kinetics and regulation of intracellular calcium during the photomechanical response of the albino rat sphincter pupillae s... 
    Krivoshik, ISBN 0-493-27444-8, UMI AAT 3017131
    DAI-B 62/06, p. 2636, Dec 2001 - 12/2001

Authored Content

  • “Astellas C3 Prize focuses on challenges of COVID-19 for people with cancer”September 2020
  • Easing the Burden of Cancer Beyond Medicine through the Astellas Oncology C3 PrizeSeptember 2020

Press Mentions

  • Frontier Medicines lures Astellas exec to be its CMO
    Frontier Medicines lures Astellas exec to be its CMOMay 13th, 2023
  • Frontier Medicines Announces Appointment of Andrew Krivoshik, M.D., Ph.D., as Chief Medical Officer
    Frontier Medicines Announces Appointment of Andrew Krivoshik, M.D., Ph.D., as Chief Medical OfficerMay 8th, 2023
  • Seagen and Astellas Complete Enrollment in EV-103 Trial Cohort K Combining PADCEV® (Enfortumab Vedotin-Ejfv) with Pembrolizumab as First-Line Treatment for Advanced Urothelial Cancer
    Seagen and Astellas Complete Enrollment in EV-103 Trial Cohort K Combining PADCEV® (Enfortumab Vedotin-Ejfv) with Pembrolizumab as First-Line Treatment for Advanced Urothelial CancerOctober 12th, 2021
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Grant Support

  • US Public Health Service National Research Service Award for Post-doctoral Research Training in Cancer Biology and TherapyNational Institutes of Health2003–2004
  • The Jim Valvano Post-Doctoral Fellowship in Pediatric Cancer ResearchV Foundation for Pediatric Cancer Research Fellow2002
  • US Public Health Service National Research Service Award for Pre-doctoral Individual MD/PhD FellowsNational Institute on Drug Abuse, National Institutes of Health1993–1998
  • US Public Health Service Institutional National Research Service Award in Molecular BiophysicsNational Institutes of Health1991–1993

Research History

  • Pediatric Hematology/Oncology FellowResearch focus in cancer biology on vasomotor activity in skin fold window chamber tumor models under mentorship of Mark Dehwirst, DVM, PhD2002 - 2004
  • PhD CandidateResearch dissertation under mentorship of Lloyd Barr, PhD: The role of calcium in smooth muscle signal transduction: The kinetics and regulation of [Ca++]i and force during the photomechanical response of rat sphincter pupillae smooth muscle1990 - 2001

Professional Memberships