AndrewSBremMD

PubMed

• 1 citations
  The Janus view: dual roles for hypoxia-inducible factor in renal repair after acute kidney injury.
  Bohan Chen, Andrew S Brem, Rujun Gong
  American Journal of Physiology. Renal Physiology. 2022-07-01
• 3 citations
  Modulation of 11β-hydroxysteroid dehydrogenase functions by the cloud of endogenous metabolites in a local microenvironment: The glycyrrhetinic acid-like factor (GALF)...
  David J. Morris, Andrew S. Brem, Alex Odermatt
  The Journal of Steroid Biochemistry and Molecular Biology. 2021-08-28
• 16 citations
  Role of gut metabolism of adrenal corticosteroids and hypertension: clues gut-cleansing antibiotics give us.
  David J. Morris, Andrew S. Brem
  Physiological Genomics. 2019-03-01

Journal Articles

• Targeting the activated mineralocorticoid receptor: Occam's razor revisited.  
  Brem, A.S., Morris, D.J., Li, X., Ge, Y., Shaw S. and Gong, R., Steroids, 1/1/2013
• Targeting the activated mineralocorticoid receptor: Occam's razor revisited.  
  Brem, A.S., Kidney Int., 1/1/2012
• Aldosterone induced fibrosis in the kidney: Questions and controversies.  
  Brem, A.S., Morris, D.J. and Gong R., American Journal of Kidney Diseases, 1/1/2011
• Direct fibrogenic effects of Aldosterone on normotensive kidney: an effect modified by 11Beta-HSD activity.  
  Brem, A.S., Morris, D.J., Ge, Y., Dworkin, L., Tolbert, E. and Gong, R., American Journal of Physiology Renal Physiology, 1/1/2010
• The Janus Effect: Two Faces of Aldosterone.  
  Brem, A.S., Kidney International, 1/1/2009
• Interactions of mineralocorticoids and glucocorticoids in epithelial target tissues revisited.  
  Morris, D.J., Latif, S.A., and Brem A.S., Steroids, 1/1/2009
• Co-localiztion of glucocorticoid metabolizing and prostaglandin synthesizing enzymes in rat kidney and liver.  
  Brem, A.S., Gong, R., Latif, S.A., and Morris D.J., Life Sciences, 1/1/2008
• Correlation of Glycyrrhetinic Acid - Like Factors (Kidney 11Beta-HSD2-GALFs) with Urinary Free Cortisol and Plasma Renin Activity in Essential Hypertension.  
  Morris, D.J., Latif, S.A., Lo, Y.H., Abrampah, K., Brem, A.S., Lichtfield, R.W., and Williams, G.H., Journal of the American Society of Hypertension, 1/1/2008
• 11Beta-Hydroxysteroid Dehydrogenase (11Beta-HSD1 and 11Beta-HSD2) in Human Kidney: 11Beta-HSD1 Co-Localizes with COX-2.  
  Gong, R., Morris, D.J. and Brem, A.S, Life Sciences, 1/1/2008
• Variable Expression of 11Beta-Hydroxysteroid Dehydrogenase (11Beta-HSD) Isoforms in Vascular Endothelial Cells.  
  Gong, R., Morris, D.J. and Brem, A.S, Steroids, 1/1/2008
• Pediatric Renal Transplantation - Historical and Current Perspectives.  
  Faizan, M.K. and Brem, A.S., Rhode Island Medicine, 1/1/2007
• Endogenous inhibitors (GALFs) of 11Beta-Hydroxysteroid Dehydrogenase isoforms 1 and 2; derivatives of adrenally produced corticosterone and cortisol.  
  Morris, D.J., Latif, S.A., Hardy, M.P., and Brem, A.S., Journal of Steroid Biochemistry, 1/1/2007
• Comparison of single pool and equilibrated Kt/V values for pediatric hemodialysis prescription management: Analysis from the Centers for Medicare & Medicaid Services C...  
  Goldstein, S.L., Brem, A.S., Warady, B., Fivush, B., and Frankenfield, D., Pediatric Nephrology, 1/1/2006
• Use of an immune function assay to monitor immunosuppression for treatment of post transplant lymphoproliferative disorder.  
  Gautam, A, Morrissey, P.E., Brem, A.S., Fischer, S.A., Gohh, R.Y., Yango, A.F. and Monaco, A.P., Pediatric Transplantation, 1/1/2006
• Factors contributing to growth hormone use in short stature pediatric hemodialysis patients.  
  Gorman, G., Fivush, B., Frankenfield, D., Warady, B., Watkins, S., Brem, A. Neu, Pediatric Nephrology, 1/1/2005
• Growth in adolescent hemodialysis patients - Longitudinal data from the Centers for Medicare & Medicaid Services End-Stage Renal Disease Clinical Performance Measures ...  
  Neu, A.M. Bedinger, M., Fivush, B.A., Warady, B.A., Watkins, S.L., Friedman, A.L., Brem, A.S., Goldstein, S.L., and Frankenfield, D.L., Pediatric Nephrology, 1/1/2005
• Chronic dialysis and access related morbidities in children.  
  Brem, A.S., Lambert, C., Kitsen, J., Somers, M., and Shemin, D.G, Dialysis and Transplantation, 1/1/2005
• Effect of CDCA on 11Beta-HSD in vascular and other tissues.  
  Morris, D.J. Souness, G.W., Latif, S.A., Hardy, M.P., and Brem, A.S., Metabolism, 1/1/2004
• Anemia in pediatric hemodialysis patients: Results from the 2001 ESRD CPM Project.  
  Frankenfield, D.L., Neu, A.M., Warady, B.A., Fivush B. A., Johnson, C.A. and Brem, A.S., Kidney International, 1/1/2003
• The functional roles of 11Beta-HSD1: Vascular tissue, testis and brain.  
  Morris, D.J., Brem, A.S., Ge, R., Jellinck, P.H., Sakai, R.R., and Hardy, M.P., Molecular Cellular Endocrinology, 1/1/2003
• Longitudinal analysis of adolescent hemodialysis patients: Results from the 2001 ESRD Clinical Performance Measures (CPM) Project.  
  Neu, A.M., Fivush, B.A., Warady, B.A., Watkins, S.L., Friedman, A.L. Brem, A.S., Goldstein, S., and Frankenfield, D.L., Pediatric Nephrology, 1/1/2003
• Prevalence of protein malnutrition in children maintained on peritoneal dialysis.  
  Brem, A.S., Lambert C., Hill, C., Kitsen J., and Shemin, D.G., Pediatric Nephrology, 1/1/2002
• 11Beta-HSD Antisense Affects Vascular Contractile Response and Glucocorticoid Metabolism.  
  Souness, G.W., Brem, A.S. and Morris, D.J., Steroids, 1/1/2002
• Clinical morbidity in pediatric dialysis patients: Data from the Network 1 Clinical Indicators Project.  
  Brem, A.S., Lambert C., Hill, C., Kitsen J., and Shemin, D.G., Pediatric Nephrology, 1/1/2001
• Insights into glucocorticoid-associated hypertension.  
  Brem, A.S., American Journal Kidney Disease, 1/1/2001
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Books/Book Chapters

• Encyclopedia of Hormones. 
  Chapter: Mineralocorticoids and Hypertension. 
  Page 700 - 704Morris, D.J. and Brem, A.S.Academic Press, San Diego, CA2003
• Gellis and Kagan's Current Pediatric Therapy 
  Chapter: The Neurogenic Bladder. 
  Page 413 - 414Brem, A.S.Editors: Burg, F.D., Ingelfinger, J.R., Wald, E.R., Polin, R.A..W.B. Saunders Company, PhiladelphiaEdition 15th,1996
• Pediatric Critical Care 
  Chapter: An Overview of Renal Structure and Function. 
  Page 659 - 669Brem, A.S.Editors: Fuhrman, B.P., Zimmerman, J.J..Mosby-Year Book, Inc., St. Louis1992
• Renal Pathophysiology: The Essentials. 
  Chapter: Tonicity Disorders. 
  Page 58 - 78Brem, A.S.Editors: Abuelo, J.G..Williams and Wilkins1989
• CAPD/CCPD in Children - Topics in Renal Medical Disease. 
  Chapter: Complications of CAPD/CCPD in Pediatric Patients. 
  Page 179 - 188Brem, A.S.Editors: Andreucci, V., Fine, R..Martinus Nijhoff Publishing, Boston, MA.1987
• Hormonal Control of Epithelial Transport. 
  Chapter: Role of cytosolic Ca and Na-Ca exchange in the action of vasopressin. 
  Page 167 - 174Taylor, A.G., Eich, E., Pearl, M., and Brem, A.S.Inserm Publisher, Paris1979
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Abstracts/Posters

• Pro-Fibrotic Effects of Aldosterone on Normal Heart and Aorta: Processes Attenuated by Endogenous Glucocorticoids and Their 11-Dehydro Metabolites.
  72. Brem, A.S., Morris, D.J. and Gong, R., J. Am. Soc. Nephrol, 1/1/2010
• Aldosterone induces pro-fibrotic changes in normal cultured renal epithelia: An effect modified by 11Beta-HSD activity.
  Brem, A.S., Morris, D.J. and Gong, R., J. Am. Soc. Nephrol, 1/1/2008
• COX-2 Co-localizes and Functionally Interacts with 11Beta-Hydroxysteroid Dehydrogenase 1 in Kidney.
  Brem, A.S., Gong R., Latif S.A., and Morris D.J., J. Am. Soc. Nephrol, 1/1/2007
• Low dose Tacrolimus therapy in pediatric patients with steroid dependent and steroid resistant nephritic syndrome.
  Faizan, M.K., Amanullah, S., and Brem, A.S., J. Am. Soc. Nephrol, 1/1/2006
• Variable Expression of 11Beta-Hydroxysteroid Dehydrogenase (11Beta-HSD) Isoforms in vascular endothelial cells.
  Brem, A.S., Gong, R., and Morris, D.J., J. Am. Soc. Nephrol, 1/1/2006
• Longitudinal Analysis fo Children Under 12 Years of Age Receiving Hemodialysis - A Report of the CMS' Clinical Performance Measures (CPM) Project
  Goldstein, S., Neu, A., Fivush, B., Warady, B., Watkins, S., Brem, A., Frankenfield, D., Pediatric Research, 1/1/2005
• Longitudinal Analysis of Intermediate Outcomes in Pediatric Hemodialysis Patients - Results of CMS' ESRD CPM Project.
  Neu, A., Goldstein, S., Fivush, B., Warady, B., Watkins, S., Brem, A., Friedman, A., Frankenfield, D., Pediatric Research, 1/1/2005
• Comparison of Single Pool (sp) versus Estimated Equilibrated (e) KT/V in Pediatric Patients Receiving Maintenance Hemodialysis (HD): A Report from CMS'CPM Project.
  Goldstein, S., Warady, B., Brem, A., Fivush, B., Frankenfield, D., Pediatric Research, 1/1/2005
• Longitudinal analysis of clinical parameters in pediatric hemodialysis patients - Results of CMS'ESRD CPM Project.
  Neu, A., Goldstein, S., Fivush, B., Warady, B., Watkins, S., Brem, A., Friedman, A., Frankenfield, D, J. Am. Soc. Nephrol, 1/1/2004
• Factors contributing to growth hormone use in short stature pediatric hemodialysis patients.
  Gorman, G., Fivush, B., Frankenfield, D., Warady, B., Watkins, S., Brem, A., Neu A., Pediatric Research, 1/1/2004
• Hemodialysis variables for children less than 12 years old: A report from the 2001 Center for Medicaid and Medicare (CMS) Clinical Performance Measures (CPM) Project.
  Goldstein, S., Neu, A., Warady B., Watkins S., Brem, A., Fivush, B., Friedman, A., Frankenfield, D., Pediatric Research, 1/1/2004
• Longitudinal analysis of children under 12 years of age receiving hemodialysis - Results of CMS'CPM Project.
  Goldstein, S., Neu, A., Fivush, B., Warady, B., Watkins, S., Brem, A., Frankenfield, D., J. Am. Soc. Nephrol, 1/1/2004
• Growth in pediatric hemodialysis patients less than 18 years - Data from the CMS ESRD CPM Project.
  Fivush, B., Neu, A., Bedinger, M., Goldstein, S., Brem, A., Warady, B., Watkins, S., Friedman, A., Frankenfield, D., J. Am. Soc. Nephrol, 1/1/2003
• Hemodialysis variables for children less than 12 years: A report from the 2001 Center Medicaid & Medicare Services CPM Project.
  Goldstein, S., Neu, A., Warady, B., Watkins, S., Brem, A., Fivush, B., Friedman, A., Frankenfield, D., J. Am. Soc. Nephrol, 1/1/2003
• Impact on specialization of primary nephrologist on care of pediatric hemodialysis patients - Data from the CMS ESRD CPM Project.
  Fivush, B., Neu, A., Bedinger, M., Warady, B., Watkins, S., Friedman, A., Brem, A., Goldstein, S., Frankenfield, D., J. Am. Soc. Nephrol, 1/1/2003
• Growth in adolescent hemodialysis patients - Longitudinal data from the CMS ESRD CPM Project.
  Neu, A. Bedinger, M., Fivush, B., Warady, B., Watkins, S., Friedman, A., Brem, A., Goldstein, S. Frankenfield, D., J. Am. Soc. Nephrol, 1/1/2003
• Impact of specialization of primary nephrologist on care of pediatric hemodialysis patients.
  Fivush, B., Neu, A., Bedinger M., Warady, B., Watkins, S., Friedman, A., Brem, A., Goldstein, S., Frankenfield, D., Pediatric Research, 1/1/2003
• Adolescent Hemodialysis - Three year longitudinal data from CMS 2002 CPM project.
  Neu, A., Fivush, B., Bedinger M., Warady, B., Watkins, S., Friedman, A., Brem, A., Goldstein, S., Frankenfield, D., Pediatric Research, 1/1/2003
• Intermediate Outcomes for Pediatric Patients with Low Hemoglobin: Results from the 2001 ESRD CPM Project.
  Frankenfield, D.L., Neu, A.M., Waraday, B.A., Fivush, B.A., Johnson, C.A. and Brem, A.S., J. Am. Soc. Nephrol, 1/1/2002
• Differential Inhibition of 11Beta-Hydroxysteroid Dehydrogenase (11Beta-HSD) Isoforms by a Bile Acid in Rat Vascular Tissue and Testicular Leydig Cells.
  Souness, G.W., Brem, A.S., Latif, S.A., Hardy, M.P., Morris, D.J., Endocrine Society 84th Meeting, San Francisco., 1/1/2002
• Improvements in Dialysis Adequacy and Anemia Status in Adolescent Hemodialysis Patients: Comparison between CMS 2000 and 2001 ESRD CPM Projects.
  Goldstein, S.L., Frankenfield, D., Neu, A, Waraday, B., Brem, A., Watkins, S., Friedman, A, and Fivush, B., Pediatric Research, 1/1/2002
• Prevalence of protein malnutrition in children maintained on peritoneal dialysis.
  Brem, A.S., Lambert C., Hill C., Kitsen J., and Shemin D.G., Journal of the American Society of Nephrology, 1/1/2001
• Clinical morbidity in pediatric dialysis patients: Data from the ESRD Clinical indicators project.
  Brem, A.S., Lambert C., Hill C., Kitsen J., and Shemin D.G., Journal of the American Society of Nephrology, 1/1/2000
• Outcome data on pediatric dialysis patients from the ESRD clinical indicators project.
  Brem, A.S., Lambert C., Hill C., Kitsen J., and Shemin D.G., Journal of the American Society of Nephrology, 1/1/1999
• Siu-Caldera, M.L., Sekimoto, H., Brem, A.S., Bina, R.B., Reddy, G.S., Abstracts of the Second Annual Meeting of the American Society of Bone and Mineral Research., 12/1/1998
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Lectures

• Pro-Fibrotic Effects of Aldosterone on Normal Heart and Aorta: Processes Attenuated by Endogenous Glucocorticoids and Their 11-Dehydro Metabolites. 
  American Society of Nephrology annual meeting, Denver. - 11/1/2010
• Pro-fibrotic effects of aldosterone on normal kidney: Processes attenuated by renal metabolites of 11Beta-HSD. 
  36th International Aldosterone Conference, San Diego, CA. - 6/17/2010
• Aldosterone induces pro-fibrotic changes in normal cultured renal epithelia: An effect modified by 11Beta-HSD activity. 
  American Society of Nephrology annual meeting, Philadelphia. - 11/1/2008
• Fistula First Update. 
  ESRD Network 1 (New England) annual meeting, Sturbridge, MA. - 10/16/2008
• COX-2 Co-localizes and Functionally Interacts with 11Beta-Hydroxysteroid Dehydrogenase 1 in Kidney. 
  American Society of Nephrology annual meeting, San Francisco. - 11/1/2007
• Interactions between mineralocorticoids and glucocorticoids in epithelial target tissues revisited. 
  Zermat Switzerland at the colloquium in honor of Bernard Rossier. - 9/1/2007
• Low dose Tacrolimus therapy in pediatric patients with steroid dependent and steroid resistant nephritic syndrome. 
  American Society of Nephrology annual meeting, San Diego. - 11/1/2006
• Variable Expression of 11Beta-Hydroxysteroid Dehydrogenase (11Beta-HSD) Isoforms in vascular endothelial cells. 
  American Society of Nephrology annual meeting, San Diego. - 11/1/2006
• Longitudinal Analysis fo Children Under 12 Years of Age Receiving Hemodialysis - A Report of the CMS' Clinical Performance Measures (CPM) Project. 
  Pediatric Academic Societies Meeting, Washington, DC. - 1/1/2005
• Longitudinal Analysis of Intermediate Outcomes in Pediatric Hemodialysis Patients - Results of CMS' ESRD CPM Project. 
  Pediatric Academic Societies Meeting, Washington, DC. - 1/1/2005
• Comparison of Single Pool (sp) versus Estimated Equilibrated (e) KT/V in Pediatric Patients Receiving Maintenance Hemodialysis (HD): A Report from CMS' CPM Project. 
  Pediatric Academic Societies Meeting, Washington, DC. - 1/1/2005
• Pathogenesis and treatment of reflux nephrolopathy. 
  American Society of Nephrology annual meeting, St. Louis. - 11/1/2004
• Longitudinal analysis of children under 12 years of age receiving hemodialysis - Results of CMS' CPM Project. 
  American Society of Nephrology annual meeting, St. Louis. - 11/1/2004
• Longitudinal analysis of clinical parameters in pediatric hemodialysis patients - Results of CMS' ESRD CPM Project. 
  American Society of Nephrology annual meeting, St. Louis. - 11/1/2004
• Factors contributing to growth hormone use in short stature pediatric hemodialysis patients. 
  APS-SPR annual meeting, San Francisco. - 5/1/2004
• Hemodialysis variables for children less than 12 years old: A report from the 2001 Center for Medicaid and Medicare (CMS) Clinical Performance Measures (CPM) Project. 
  APS-SPR annual meeting, San Francisco. - 5/1/2004
• Growth in pediatric hemodialysis patients less than 18 years - Data from the CMS ESRD CPM Project. 
  American Society of Nephrology annual meeting, San Diego, CA. - 11/1/2003
• Hemodialysis variables for children less than 12 years: A report from the 2001 Center Medicaid & Medicare Services CPM Project. 
  American Society of Nephrology annual meeting, San Diego, CA. - 11/1/2003
• Impact on specialization of primary nephrologist on care of pediatric hemodialysis patients - Data from the CMS ESRD CPM Project. 
  American Society of Nephrology annual meeting, San Diego, CA. - 11/1/2003
• Growth in adolescent hemodialysis patients - Longitudinal data from the CMS ESRD CPM Project. 
  American Society of Nephrology annual meeting, San Diego, CA. - 11/1/2003
• Impact of specialization of primary nephrologist on care of pediatric hemodialysis patients. 
  APS-SPR annual meeting, Seattle. - 5/1/2003
• Adolescent Hemodialysis - Three year longitudinal data from CMS 2002 CPM project. 
  APS-SPR annual meeting, Seattle. - 5/1/2003
• Intermediate Outcomes for Pediatric Patients with Low Hemoglobin: Results from the 2001 ESRD CPM Project. 
  American Society of Nephrology annual meeting, Philadelphia. - 11/1/2002
• Differential Inhibition of 11Beta-Hydroxysteroid Dehydrogenase (11Beta-HSD) Isoforms by a Bile Acid in Rat Vascular Tissue and Testicular Leydig Cells. 
  84th annual meeting of the Endocrine Society, San Francisco. - 6/1/2002
• Improvements in Dialysis Adequacy and Anemia Status in Adolescent Hemodialysis Patients: Comparison between CMS 2000 and 2001 ESRD CPM Projects. 
  APS-SPR annual meeting, Baltimore. - 5/1/2002
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Other

• Conflicts, controversy, and constants: The Flux of American Medicine. 
  Brem, A.S.
  Brown University Faculty Bulletin - 1/1/2004