Andrei Goga MD PhD

Breast Cancer

Professor, Cell & Tissue Biology and Medicine, UCSF

Education & Training

University of California (San Francisco)Fellowship, Hematology and Medical Oncology, 1999 - 2001
David Geffen School of Medicine at UCLAClass of 1997

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Elected Member The American Society for Clinical Investigation, 2011

PubMed

Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway.
Jun Hyoung Park, Kwang Hwa Jung, Dongya Jia, Sukjin Yang, Kuldeep S Attri
Cell Reports. Medicine. 2025-02-18
Tumor Cell Spatial Organization Directs EGFR/RAS/RAF Pathway Primary Therapy Resistance through YAP Signaling.
Rachel Nakagawa, Andrew Beardsley, Sophia Durney, Mary-Kate Hayward, Vishvak Subramanyam
Biorxiv. 2025-01-31
2 citations
Single-cell analysis of breast cancer metastasis reveals epithelial-mesenchymal plasticity signatures associated with poor outcomes.
Juliane Winkler, Weilun Tan, Catherine Mm Diadhiou, Christopher S McGinnis, Aamna Abbasi
The Journal of Clinical Investigation. 2024-09-03

Journal Articles

Aurora Kinase A Drives the Evolution of Resistance to Third-Generation EGFR Inhibitors in Lung Cancer
Victoria E Wang, Collin M Blakely, Trever G Bivona, Andrei Goga, Nature
Cancer Cells Exploit an Orphan RNA to Drive Metastatic Progression
Andrei Goga, MD, Nature

A High-Content Screen Identifies the Vulnerability of MYC-Overexpressing Cells to DimethylfasudilMarch 24th, 2021
$3M Award Lays Foundation for New Scientific Collaborations at Parnassus Heights CampusJanuary 7th, 2021
‘Orphan’ RNAs Make Cancer Deadlier, but Potentially Easier to DiagnoseNovember 7th, 2018
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Development of CapCell Scope for Metabolic Imaging of Tissue Heterogeneity and Therapy ResponseDUKE UNIVERSITY2024–2028
Development of CapCell Scope for Metabolic Imaging of Tissue Heterogeneity and Therapy ResponseDUKE UNIVERSITY2024–2028
Development of CapCell Scope for Metabolic Imaging of Tissue Heterogeneity and Therapy ResponseDUKE UNIVERSITY2024–2028
Understanding CDK1 Function and Cancer VulnerabilitiesUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2023–2028
Understanding breast cancer progression as a defect in the mechanics of tissue self-organizationUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2020–2025
Molecular and Cellular Mechanisms in CancerUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2004–2025
Molecular and Cellular Mechanisms in CancerUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2004–2025
Molecular and Cellular Mechanisms in CancerUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2004–2025
Molecular and Cellular Mechanisms in CancerUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2004–2025
Molecular and Cellular Mechanisms in CancerUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2004–2025

Professor, Dept Cell & Tissue Biology and MedicineOncogene Signaling Activation of proto-oncogenes results in alterations of multiple signaling pathways, resulting in the rewiring of cell proliferation, metabolism and small RNA circuits which contribute to the tumorigenic state. We seek to discover new therapies for patients.2015 - Present