AndrasHeczeyMD

Associate professor, Pediatric Hematology & Oncology, Baylor College of Medicine

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Dr. Andras Heczey's research focuses on developing novel treatments for children with solid tumors by redirecting the immune system to attack and kill cancer cells by using genetically-engineered T cells and Natural Killer T cells. He developed bispecific T cell engagers and chimeric antigen receptors which specifically target several solid tumors (including hepatoblastoma, hepatocellular carcinoma, yolk sac tumors, Wilms tumor, rhabdoid tumors etc) when expressed in T cells.
As the Director of the Liver Tumor Center, Dr. Heczey developed a strategy to target glypican-3 (GPC3) with genetically-engineered T lymphocytes. His team is currently evaluating Interleukin-15 and GPC3-CAR expressing T cells in children with solid tumors.
His ultimate goal is to cure all patients with solid cancers by effectively translating preclinical findings from bench-to-bedside.

Baylor College of MedicineFellowship, Pediatric Hematology/Oncology, 2009 - 2012
Children's Hospital Los AngelesResidency, Pediatrics, 2006 - 2009
Semmelweis UniversityClass of 2002

PubMed

DRIMS: A Synthetic Biology Platform that Enables Deletion, Replacement, Insertion, Mutagenesis, and Synthesis of DNA.
Leidy D Caraballo G, Inci Cevher Zeytin, Purva Rathi, Che-Hsing Li, Ai-Ni Tsao
ACS Synthetic Biology. 2025-02-21
Long-term outcomes of GD2-directed CAR-T cell therapy in patients with neuroblastoma.
Che-Hsing Li, Sandhya Sharma, Andras A Heczey, Mae L Woods, David H M Steffin
Nature Medicine. 2025-02-17
Cardiovascular Complications of Immune Effector Cell Therapies in Pediatric Hematological and Solid Tumors.
Aaron B Ross, Kriti Puri, Thomas L Johnson, Lilliam D Correa, Tami D John
Pediatric Blood & Cancer. 2025-01-20

From Bench to Bedside and Back: CAR T Cells Armed with IL-15 Show Promise in Treating Solid CancersJanuary 28th, 2025
CAR T Cells Armed with IL-15 Show Promise in Treating Solid CancersNovember 27th, 2024
Promising Results for CAR-NKT Cell Therapy Against Neuroblastoma in Phase 1 TrialMay 16th, 2023
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