AmySehnertMD

Pediatric Cardiology • San Francisco, CA

Vice President, Clinical Science

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Office
331 Panorama Drive
San Francisco, CA 94131
Phone+1 415-297-6428

Education & Training

University of California (San Francisco)Fellowship, Pediatric Cardiology, 1995 - 1999
University of ColoradoResidency, Pediatrics, 1992 - 1995
University of Minnesota Medical SchoolClass of 1992

Certifications & Licensure

CA State Medical License 1995 - 2025

Clinical Trials

Genetic Substudy of the Alternans Before Cardioverter Defibrillator (ABCD) Trial Start of enrollment: 2007 Jan 01
Completed
MatErnal BLood IS Source to Accurately Diagnose Fetal Aneuploidy Start of enrollment: 2010 Jun 01
Completed
Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Start of enrollment: 2018 May 29
Completed
Phase 3
Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEER Start of enrollment: 2018 Apr 26
Completed
Phase 2
A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM Start of enrollment: 2018 Oct 05
Active, not recruiting
Phase 2, Phase 3
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Publications & Presentations

PubMed

4 citations
Patient-Level Artificial Intelligence-Enhanced Electrocardiography in Hypertrophic Cardiomyopathy: Longitudinal Treatment and Clinical Biomarker Correlations.
Konstantinos C Siontis, Sean Abreau, Zachi I Attia, Joshua P Barrios, Thomas A Dewland
JACC. Advances. 2023-10-01
19 citations
Effects of Mavacamten on Measures of Cardiopulmonary Exercise Testing Beyond Peak Oxygen Consumption: A Secondary Analysis of the EXPLORER-HCM Randomized Trial.
Matthew T Wheeler, Iacopo Olivotto, Perry M Elliott, Sara Saberi, Anjali T Owens
JAMA Cardiology. 2023-03-01
14 citations
Effect of beta-blocker therapy on the response to mavacamten in patients with symptomatic obstructive hypertrophic cardiomyopathy.
Matthew T Wheeler, Daniel Jacoby, Perry M Elliott, Sara Saberi, Sheila M Hegde
European Journal of Heart Failure. 2023-02-01

Press Mentions

Using AI in Electrocardiogram Analysis Can Improve Diagnosis and Treatment of Hypertrophic CardiomyopathyMarch 7th, 2022
Results from Two Phase 3 Studies Evaluating CAMZYOS (Mavacamten) for Symptomatic Obstructive Hypertrophic Cardiomyopathy (HCM) Released by Bristol Myers SquibbSeptember 6th, 2023
Results from Two Phase 3 Studies Evaluating Mavacamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy ReleasedSeptember 10th, 2023