AmySehnertMD

Pediatric Cardiology • San Francisco, CA

Vice President, Clinical Science

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Office
331 Panorama Drive
San Francisco, CA 94131
Phone+1 415-297-6428

Education & Training

University of California (San Francisco)Fellowship, Pediatric Cardiology, 1995 - 1999
University of ColoradoResidency, Pediatrics, 1992 - 1995
University of Minnesota Medical SchoolClass of 1992

Certifications & Licensure

CA State Medical License 1995 - 2025

Clinical Trials

Genetic Substudy of the Alternans Before Cardioverter Defibrillator (ABCD) Trial Start of enrollment: 2007 Jan 01
Completed
MatErnal BLood IS Source to Accurately Diagnose Fetal Aneuploidy Start of enrollment: 2010 Jun 01
Completed
Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Start of enrollment: 2018 May 29
Completed
Phase 3
Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEER Start of enrollment: 2018 Apr 26
Completed
Phase 2
A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM Start of enrollment: 2018 Oct 05
Active, not recruiting
Phase 2, Phase 3
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Publications & Presentations

PubMed

443 citations
Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial
Iacopo Olivotto, Artur Oreziak, Roberto Barriales-Villa, Theodore P. Abraham, Ahmad Masri
Lancet. 2020-09-12
33 citations
Study Design and Rationale of VALOR-HCM: Evaluation of Mavacamten in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy who are Eligible for Septal Reduct...
Milind Y. Desai, Kathy Wolski, Anjali T. Owens, Srihari S. Naidu, Jeffrey B. Geske
American Heart Journal. 2021-05-23
180 citations
Evaluation of Mavacamten in Symptomatic Patients With Nonobstructive Hypertrophic Cardiomyopathy
Carolyn Y. Ho, Matthew E Mealiffe, Richard G. Bach, Mondira Bhattacharya, Lubna Choudhury
Journal of the American College of Cardiology. 2020-06-02

Press Mentions

Using AI in Electrocardiogram Analysis Can Improve Diagnosis and Treatment of Hypertrophic CardiomyopathyMarch 7th, 2022
Results from Two Phase 3 Studies Evaluating CAMZYOS (Mavacamten) for Symptomatic Obstructive Hypertrophic Cardiomyopathy (HCM) Released by Bristol Myers SquibbSeptember 6th, 2023
Results from Two Phase 3 Studies Evaluating Mavacamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy ReleasedSeptember 10th, 2023