AmyAnnMrazekMDPhD

Burn, Trauma Surgery & Surgical Critical Care

Assistant Professor at the University of Texas Medical Branch (UTMB) - Galveston

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Office
3.124 Trauma Center
301 University Blvd.
Galveston, TX 77555
Phone+1 409-772-9066

Fax+1 409-747-7319

I am a board-certified general surgeon and fellowship trained in surgical critical care and acute burn surgery in both adult and pediatric patients. At the University of Texas Medical Branch (UTMB), I am an Assistant Professor within the Department of Surgery, Division of Burns, Trauma, and Acute Care Surgery. I am also an acute burn surgeon and critical care consultant at Shriners Children’s Texas Hospital in Galveston.

University of Texas Medical Branch HospitalsFellowship, Surgical Critical Care, 2021 - 2022
University of Texas Medical Branch HospitalsResidency, Surgery, 2010 - 2019
University of Texas Medical BranchPhD, Recurrent acute pancreatitis, 2013 - 2015
University of Texas Medical Branch School of MedicineClass of 2010, MD
Texas A&M UniversityBS, Biomedical science and Chemistry, Summa cum laude, 2001 - 2005

1st place in Basic Science Research Singleton Surgical Society, 2013-2014
Best overall poster/presentation Sigma Xi, Medical Student Research Program, 2007
Alumni Scholarship UTMB - School of Medicine, 2006
Presidential Top Scholarship Texas A&M - Corpus Christi, 2001-2005
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PubMed

14 citations
Colorectal Cancer-Associated Fibroblasts are Genotypically Distinct.
Amy A. Mrazek, Joseph R. Carmical, Thomas G. Wood, Mark R. Hellmich, Mahmoud A. Eltorky
Current Cancer Therapy Reviews. 2014-01-01
41 citations
Heart rate variability analysis is more sensitive at identifying neonatal sepsis than conventional vital signs
Fredrick J. Bohanon, Amy A. Mrazek, Mohamed T. Shabana, Sarah Mims, Geetha L. Radhakrishnan
American Journal of Surgery. 2015-10-01
18 citations
Increased coagulation and suppressed generation of activated protein C in aged mice during intra-abdominal sepsis.
Marlene E. Starr, Hitoshi Takahashi, Daiki Okamura, Brittany A. Zwischenberger, Amy A. Mrazek
American Journal of Physiology. Heart and Circulatory Physiology. 2015-01-15

Journal Articles

Triple negative breast cancer: a review of clinicopathologic characteristics and treatment options.
1. Porro LJ, Mrazek AA, Chao C, The Open Breast Cancer Journal, 6/2014

Lectures

Apigenin limits pancreatic injury in recurrent acute pancreatitis by inhibiting MAPK pathway activation.
Academic Surgical Congress, Jacksonville, FL - 2/2/2016
Apigenin reduces PTHrP-mediated inflammation, PSC proliferation, and ECM synthesis in pancreatitis.
Academic Surgical Congress, Las Vegas, NV - 2/3/2015
Apigenin minimizes SMAD-dependent and independent TGF-β signaling by acinar cells in an in vitro model of chronic pancreatitis.
American College of Surgeons Clinical Congress, San Francisco, CA - 10/29/2014
Apigenin decreases pErk and pAkt expression by acinar cells in an in vitro model of chronic pancreatitis.
South Texas Chapter of the American College of Surgeons, Austin, TX - 2/21/2014
Radhakrishnan RS. Heart rate variability analysis is more sensitive at identifying neonatal sepsis than conventional vital signs.
9th Annual Academic Surgical Congress, San Diego, CA - 2/4/2014
Genetic and epigenetic changes in carcinoma-associated fibroblasts derived from human colorectal cancers.
American College of Surgeons Clinical Congress, Washington, DC - 10/8/2013
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Preclinical development of a pharmacologic agent for the treatment of recurrent acute pancreatitis.August 2015

Clinical outcomes researchAcute burns and pancreatitis2022 - 2023
Quality improvement projectStandardization of post-operative burn wound care2021 - 2021
Quality Improvement ProjectField: Non-narcotic, multi-modal pain control in post-operative care Mentor: John P. Walker, MD Dept. of Surgery, UTMB2018 - 2019
T32 Research fellowField: Gastrointestinal molecular mechanisms in the study of pancreatitis. PI: Mark R. Hellmich, PhD, and Celia Chao, MD Grant: T32 DK763920, Dept. of Surgery, UTMB2012 - 2015
Research assistantField: Sepsis and immunosenescence PI: Hiroshi Saito, PhD Dept. of Surgery, UTMB2007 - 2009
Research assistantField: Microvascular research Supervisor: Wassim Choucair, MD Cardiology Associates of Corpus Christi2004 - 2006

UTMB provider profilehttps://doctors.utmbhealth.com/providersearch/default/?id=011714
SHC provider profilehttps://www.shrinerschildrens.org/en/our-care-providers/amy-a-mrazek-md-phd-42689