AmyElizabethMcKeeMD

PubMed

• 26 citations
  Cancer drugs approved for use in children: Impact of legislative initiatives and future opportunities
  Amy Barone, Denise Casey, Amy E. McKee, Gregory H. Reaman
  Pediatric Blood & Cancer. 2019-08-01
• 1 citations
  Proceedings of a Workshop: US Food and Drug Administration-International Society of Pharmacometrics Model-Informed Drug Development in Oncology
  Rene Bruno, Jin Y. Jin, Kimberly Maxfield, Lauren Milligan, Chao Liu
  Clinical Pharmacology and Therapeutics. 2019-07-01
• 1 citations
  U.S. Food and Drug Administration Benefit‐Risk Assessment of Nilotinib Treatment Discontinuation in Patients with Chronic Phase Chronic Myeloid Leukemia in a Sustained...
  E. Dianne Pulte, Tanya Wroblewski, Erik Bloomquist, Shenghui Tang, Ann T. Farrell
  The Oncologist. 2019-05-01

Journal Articles

• FDA Approval Summary: Olaparib Monotherapy in Patients with Deleterious Germline BRCA-Mutated Advanced Ovarian Cancer Treated with Three or More Lines of Chemotherapy.  
  Kim G, Ison G, McKee AE, Zhang H, Tang S, Gwise T, Sridhara R, Lee E, Tzou A, Philip R, Chiu HJ, Ricks TK, Palmby T, Russell AM, Ladouceur G, Pfuma E, Li H, Zhao L, Li..., Clin Cancer Res, 2015
• NCCN Working Group report: designing clinical trials in the era of multiple biomarkers and targeted therapies.  
  Venook AP, Arcila ME, Benson AB 3rd, Berry DA, Camidge DR, Carlson RW, Choueiri TK, Guild V, Kalemkerian GP, Kurzrock R, Lovly CM, McKee AE, Morgan RJ, Olszanski AJ, R..., J Natl Compr Canc Netw, 2014
• PKC-mediated survival signaling in breast carcinoma cells: a role for MEK1-AP1 signaling.  
  Weldon CB, McKee A, Collins-Burow BM, Melnik LI, Scandurro AB, McLachlan JA, Burow ME, Beckman BS., Int J Oncol, 2005
• Cross-talk between phosphatidylinositol-3 kinase and sphingomyelinase pathways as a mechanism for cell survival/death decisions  
  Burow ME, Weldon CB, Collins-Burow BM, Ramsey N, McKee A, Klippel A, McLachlan JA, Clejan S, Beckman BS., J Biol Chem, 2000
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Abstracts/Posters

• Unlike Other Cancers, Neuroblastoma Contains a High Frequency of Tumor-initiating Cells with Stem Cell-Like Behavior.
  Amy E. McKee, Loen M. Hansford, David Venzon, David R. Kaplan, Carol J. Thiele., Advances in Neuroblastoma Research Meeting, 2008
• BDNF/TrkB pathway upregulates PTHrP in neuroblastoma.
  Amy E. McKee, Kelly Martin, Ana Markovic, Braden T. Greer, Jun S. Wei, Qing R. Chen, Javed Khan, and Carol J. Thiele., American Association of Cancer Research Annual Meeting, 2006
• PTHrP, a Mediator of Bone Metastasis, Is a Target of TrkB but Not TrkA in Neuroblastoma.
  Amy E McKee, Kelly Martin, Katsuya Nakamura, Braden Greer, Jun Wei, Javed Khan, Carol J Thiele., Advances in Neuroblastoma Research, 2006
• AP-1 transcriptional activation in MCF-7 breast carcinoma cells is dependent on intact PKC/MAPK.
  McKee A, Burrow ME, Scandurro AB, Beckman BS., American Association of Cancer Research Annual Meeting, 1999
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Lectures

• Regulatory Science: The Challenges with "SMALL DATA": Small Trials, Off-Label Use, and Single Patient INDs—Are We Doing Enough? 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/3/2018