Alvaro Pascual-Leone MD PhD

Neurology•Boston, MA

Neurophysiology, Dementia & Geriatrics

Medical Director, Deanna and Sidney Wolk Center for Memory Health - Hebrew SeniorLife Professor of Neurology, Harvard Medical School

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Hebrew SeniorLife1200 Centre StBoston, MA 02131
Phone+1 617-383-8600
Fax+1 289-271-4398

Education & Training

University of MinnesotaResidency, Neurology, 1986 - 1990
Albert Ludwigs University Faculty of MedicineClass of 1985

Certifications & Licensure

MA State Medical License 1997 - 2025
MN State Medical License 1988 - 1997
American Board of Psychiatry and Neurology Neurology

Clinical Trials

tDCS and Physical Therapy in Stroke Start of enrollment: 2007 Sep 01
Completed
Not Applicable
Transcranial Magnetic Stimulation to Improve Speech in Aphasia Start of enrollment: 2002 Jul 01
Completed
Phase 1
rTMS for Motor and Mood Symptoms of Parkinson's Disease Start of enrollment: 2010 May 01
Completed
Not Applicable
TMS Measures of Plasticity and Excitatory/Inhibitory Ratio as Biomarkers: R-baclofen Effects in Normal Volunteers Start of enrollment: 2010 Oct 01
Terminated
Phase 1
Effects of a Combined Transcranial Magnetic Stimulation (TMS) and Cognitive Training in Alzheimer Patients Start of enrollment: 2010 Dec 01
Completed
Not Applicable
Therapeutic Efficacy of Transcranial Magnetic Stimulation in Schizophrenia Start of enrollment: 2012 Feb 01
Completed
Not Applicable
Effect of NeuroAD on the Cognitive Function of Alzheimer Patients Start of enrollment: 2013 Oct 01
Completed
Not Applicable
Transcranial Magnetic Stimulation in Spino-Cerebellar Ataxia Start of enrollment: 2013 Sep 01
Completed
Not Applicable
Effect of Modulating Gamma Oscillations Using tACS Start of enrollment: 2018 Aug 02
Completed
Not Applicable
Temporal Interference Brain Stimulation Start of enrollment: 2019 Sep 19
Active, not recruiting
Not Applicable
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Publications & Presentations

PubMed

Big non-invasive brain stimulation data (Big NIBS data): An open-access platform and repository for NIBS data.
Daniel T Corp, Hannah G K Bereznicki, Michael P Barham, Gillian M Clark, Benjamin J Chadwick
Brain Stimulation. 2025-02-20
Recommendations for the Safe Application of Temporal Interference Stimulation in the Human Brain Part I: Principles of Electrical Neuromodulation and Adverse Effects.
Antonino M Cassarà, Taylor H Newton, Katie Zhuang, Sabine J Regel, Peter Achermann
Bioelectromagnetics. 2025-02-01
Reevaluating the Role of Education in Cognitive Decline and Brain Aging: Insights from Large-Scale Longitudinal Cohorts across 33 Countries.
Anders M Fjell, Ole Røgeberg, Øystein Sørensen, Inge K Amlien, David Bartrés-Faz
Medrxiv. 2025-01-29

Journal Articles

Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis
Brian J Wainger, Nicholas J Maragakis, Richard Bedlack, Namita A Goyal, Seward B Rutkove, Michael H Rivner, Stephen A Goutman, Shafeeq S Ladha, Elizabeth A Mauricio, R..., JAMA Neurology

Lectures

An Introduction to the Clinical Practice of Transcranial Magnetic Stimulation
Harvard Medical School ,Department Of Continuing Education, Boston, Massachusetts - 6/24/2013
Intensive Course in Transcranial Magnetic Stimulation
Harvard Medical School ,Department Of Continuing Education, Boston, Massachusetts - 6/24/2013
Introduction to Transcranial Direct Current Stimulation in Neuropsychiatric Research
Harvard Medical School, Boston, Massachusetts - 11/3/2012
Intensive Course in Transcranial Magnetic Stimulation
Harvard Medical School, Boston, Massachusetts - 10/29/2012
An Introduction to the Clinical Practice of Transcranial Magnetic Stimulation
Harvard Medical School, Boston, Massachusetts - 10/29/2012
An Introduction to the Clinical Practice of Transcranial Magnetic Stimulation
Harvard Medical School, Boston, Massachusetts - 6/25/2012
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Press Mentions

Anywhere for Health Systems™ Delivers Clinical-Grade Cognitive Assessments RemotelyMarch 18th, 2025
Linus Health Achieves Landmark Research Recognition Across Peer-Reviewed Medical and Scientific JournalsMarch 5th, 2025
Rapidly Progressive Dementia: Reasons for a Sudden Worsening of Dementia SymptomsJanuary 30th, 2025
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Grant Support

Multifocal transcranial current stimulation for cognitive and motor dysfunction in dementiaHEBREW REHABILITATION CENTER FOR AGED2022–2027

Professional Memberships

American Academy of Neurology - AAN
Member