Alphonse G Taghian MD FASTRO

Radiation Oncology•Boston, MA

Professor, Radiation Oncology-Massachusetts General Hospital, Harvard Medical School

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100 Blossom St Cox 1Boston, MA 02114
Phone+1 617-726-6050
Fax+1 617-726-3603

Education & Training

Alexandria University Faculty of MedicineClass of 1980

Certifications & Licensure

NH State Medical License 2024 - 2026
MA State Medical License 1995 - 2025
ME State Medical License 2020 - 2021
American Board of Radiology Radiation Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2010-2014
America's Top Doctors for Cancer Castle Connolly, 2010-2013
Boston Magazine Castle Connolly, 2009-2013
Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2012
Super Doctor SuperDoctors.com
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Clinical Trials

Neoadjuvant Chemotherapy Using Doxorubicin and Paclitaxel in Treating Women With Large Breast Cancer Start of enrollment: 2000 Feb 01
Completed
Phase 2
Radiation Therapy (WBI Versus PBI) in Treating Women Who Have Undergone Surgery For Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer Start of enrollment: 2005 Mar 01
Completed
Not Applicable
Partial Breast Irradiation (PBI) for Selected Patients With Early Invasive or Non-Invasive Breast Cancer Start of enrollment: 2003 Sep 01
Completed
Not Applicable
Early Detection and Intervention for Mild and Moderate Lymphedema in Patients Treated for Breast Cancer Start of enrollment: 2009 Aug 01
Terminated
Not Applicable
Treatment of T1N0 Invasive Breast Carcinoma by Local Excision Implant Start of enrollment: 1997 Jun 01
Completed
Phase 1, Phase 2
Non-Invasive Imaging for Cording in Breast Cancer Patients Start of enrollment: 2011 Aug 01
Completed
Not Applicable
Prospective Screening for Breast Cancer-related Lymphedema
RECRUITING
Evaluation of BIS for Quantification of Lymphedema
COMPLETED
External-Beam Partial-Breast Irradiation for Early Breast Cancer 40 Gy QD Over 2 Weeks Start of enrollment: 2012 May 01
Completed
Not Applicable
Naltrexone RCT for Treatment-Emergent Fatigue in Patients Receiving Radiation Therapy for Breast Cancer Start of enrollment: 2014 May 01
Terminated
Phase 2
Exploring the Efficacy and Feasibility of the LymphaTech Scanner for Breast Cancer-Related Lymphedema Screening Start of enrollment: 2019 Jan 30
ACTIVE_NOT_RECRUITING
NA
Patient Experiences with the COVID-19 Vaccination After Breast Cancer Treatment Start of enrollment: 2021 May 07
COMPLETED
Screening for BCRL in Targeted Therapy for Breast Cancer Start of enrollment: 2018 Dec 13
RECRUITING
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

Impact of Prepectoral Implant Placement and Radiation Modalities (Protons/Photons/Dosimetry) in Mastectomy Patients Undergoing Immediate Single Stage Direct-to-Implant...
George E Naoum, Hazim S Ababneh, Andrzej Niemierko, Laura Salama, Myrsini Ioannidou
International Journal of Radiation Oncology, Biology, Physics. 2025-04-01
Defining the Optimal Dose for 3-Dimensional Conformal Accelerated Partial Breast Irradiation: 15-Year Follow-Up of a Dose-Escalation Trial.
Alphonse G Taghian, George E Naoum, Lior Z Braunstein, Andrzej Niemierko, Barbara L Smith
International Journal of Radiation Oncology, Biology, Physics. 2025-03-15
8 citations
Hypofractionated vs Conventionally Fractionated Postmastectomy Radiation After Implant-Based Reconstruction: A Randomized Clinical Trial.
Julia S Wong, Hajime Uno, Angela C Tramontano, Lauren Fisher, Catherine V Pellegrini
JAMA Oncology. 2024-10-01

Journal Articles

Lymph Node Metastases Can Invade Local Blood Vessels, Exit the Node, and Colonize Distant Organs in Mice
Alphonse Taghian, MD, Science Magazine

Press Mentions

Optimizing Treatment for Older Patients with HR+ Low-Risk Breast CancerJanuary 5th, 2023
Gene Signature May Spare Some Breast Cancer Patients from RadiationDecember 14th, 2022
Do I Have to Get the Covid Vaccine in My Arm?April 29th, 2021
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