AlexandraPTurnerMD

PubMed

• 145 citations
  Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates
  Timothy A Weaver, Ali H. Charafeddine, Avinash Agarwal, Alexandra P. Turner, Maria Russell
  Nature Medicine. 2009-07-01
• 1232 citations
  mTOR regulates memory CD8 T-cell differentiation
  Koichi Araki, Alexandra P. Turner, Virginia O. Shaffer, Shivaprakash Gangappa, Susanne A. Keller
  Nature. 2009-07-02
• 9 citations
  The Role of Implicit Bias in Surgical Resident Evaluations.
  Arabella Dill-Macky, Chiu-Hsieh Hsu, Leigh A Neumayer, Valentine N Nfonsam, Alexandra P Turner
  Journal of Surgical Education. 2021-12-29

Journal Articles

• Extended distal pancreatectomy for pancreatic adenocarcinoma with splenic vein thrombosis and adjacent organ invasion  
  Roch AM, Singh H, Turner AP, Ceppa EP, House MG, Zyromski NJ, Nakeeb A, Schmidt CM, Am J Surg, 1/1/2015
• Belatacept and sirolimus prolong allograft survival in nonhuman primates: adverse consequences of concomitant alefacept therapy  
  Lowe MC, Badell IR, Turner AP, Thompson PW, Leopardi FV, Strobert EA, Larsen CP, Kirk AD, Am J Transplant, 1/1/2013
• Induction immunosuppression in liver transplantation: a review  
  Turner AP, Knechtle SJ, Transplant Int, 1/1/2013
• Alternative immunomodulatory strategies for xenotransplantation: CD40/154 pathway-sparing regimens promote xenograft survival  
  Thompson P, Badell IR, Lowe M, Turner A, Cano J, Avila J, Azimzadeh A, Cheng X, Pierson RN, Johnson B, Robertson J, Song M, Leopardi F, Strobert E, Korbutt G, Rayat G,..., Am J Transplant, 1/1/2012
• Nondepleting anti-CD40-based therapy prolongs allograft survival in nonhuman primates  
  Badell IR, Thompson PW, Turner AP, Russell MC, Avila JG, Cano JA, Robertson JM, Leopardi FV, Strobert EA, Iwakoshi NN, Reimann KA, Ford ML, Kirk AD, Larsen CP, Am J Transplant, 1/1/2012
• Sirolimus enhances the magnitude and quality of viral-specific CD8+ T-cell responses to vaccinia virus vaccination in rhesus macaques  
  Turner AP, Shaffer VO, Araki K, Martens C, Turner PL, Gangappa S, Ford ML, Ahmed R, Kirk AD, Larsen CP, Am J Transplant., 1/1/2011
• LFA-1 specific therapy prolongs allograft survival in rhesus macaques  
  Badell IR, Russell MC, Thompson PW, Turner AP, Weaver TA, Robertson JM, Avila JG, Cano JA, Johnson BE, Song M, Leopardi FV, Swygert S, Strobert EA, Ford ML, Kirk AD, L..., J Clin Invest., 1/1/2010
• GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation ...  
  Miller WP, Srinivasan S, Panoskaltsis-Mortari A, Singh K, Sen S, Hamby K, Deane T, Stempora L, Beus J, Turner A, Wheeler C, Anderson DC, Sharma P, Garcia A, Strobert E..., Blood, 1/1/2010
• Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses  
  Ferrer IR, Wagener ME, Robertson JM, Turner AP, Araki K, Ahmed R, Kirk AD, Larsen CP, Ford ML, J Immunol, 1/1/2010
• mTOR regulates memory CD8 T-cell differentiation  
  Araki K, Turner AP, Shaffer VO, Gangappa S, Keller SA, Bachmann MF, Larsen CP, Ahmed R, Nature, 1/1/2009
• Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates  
  Weaver TA, Charafeddine AH, Agarwal A, Turner AP, Russell M, Leopardi FV, Kampen RL, Stempora L, Song M, Larsen CP, Kirk AD, Nature Medicine, 1/1/2009
• The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response  
  Zhou J, Liu CY, Back SH, Clark RL, Peisach D, Xu Z, Kaufman RJ, Proceedings of the National Academy of Sciences, 1/1/2006
• Insights into the formation of a [2Fe-2S] iron-sulfur cluster in an Escherichia coli thioredoxin mutant  
  Collet JF, Peisach D, Bardwell JC, Xu Z, Protein Science, 1/1/2005
• Crystal structure of the C-terminal domain of the two-component system transmitter protein nitrogen regulator II (NRII; NtrB), regulator of nitrogen assimilation in Es...  
  Song Y, Peisach D, Pioszak AA, Xu Z, Ninfa AJ, Biochemistry, 1/1/2004
• The crystal structure of choline kinase reveals a eukaryotic protein kinase fold  
  Peisach D, Gee P, Kent C, Xu Z, Structure, 1/1/2003
• Effects of the E177K mutation in D-amino acid transaminase Studies on an essential coenzyme anchoring group that contributes to stereochemical fidelity  
  van Ophem PW, Peisach D, Erickson SD, Soda K, Ringe D, Manning JM, Biochemistry, 1/1/1999
• Crystallographic study of steps along the reaction pathway of D-amino acid aminotransferase  
  Peisach D, Chipman DM, Van Ophem PW, Manning JM, Ringe D, Biochemistry, 1/1/1998
• Crystal structures of L201A mutant of D-amino acid aminotransferase at 20 A resolution: implication of the structural role of Leu201 in transamination  
  Sugio S, Kashima A, Kishimoto K, Peisach D, Petsko GA, Ringe D, Yoshimura T, Esaki N, Protein Engineering, 1/1/1998
• Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins  
  Brenner C, Garrison P, Gilmour J, Peisach D, Ringe D, Petsko GA, Lowenstein JM, Nature Structural Biology, 1/1/1997
• Catalytic ability and stability of two recombinant mutants of D-amino acid transaminase involved in coenzyme binding  
  Van Ophem PW, Pospischil MA, Ringe D, Peisach D, Petsko G, Soda K, Manning JM, Protein Science, 1/1/1995
• Asymmetric induction in manganese(III)-based oxidative free-radical cyclizations of phenylmenthyl acetoacetates and 2,5-dimethylpyrrolidine acetoacetamides  
  Zhang Q, Mohan RM, Cook L, Kazanis S, Peisach D, Foxman BM, Snider BB, The Journal of Organic Chemistry, 1/1/1993
• Calcium ATPase of sarcoplasmic reticulum has four binding sites for calcium  
  Jencks WP, Yang T, Peisach D, Myung J., Biochemistry, 1/1/1993
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Books/Book Chapters

• Textbook of Organ Transplantation 
  Chapter: Patient selection and indications for organ transplantation: pancreas and islet transplantation 
  Turner AP and Turgeon NAEditors: Kirk AD.Wiley Blackwell, Oxford, UK2014
• Textbook of Organ Transplantation 
  Chapter: Histopathological syndromes of graft rejection and recurrent disease: VCA 
  Turner AP and Cendales LCEditors: Kirk AD.Wiley Blackwell, Oxford, UK2014

Abstracts/Posters

• The impact of HCV on post transplant biliary strictures
  Kemmer N, Franco E, Turner A, Albers C, Horkan J, Parkinson E, Cece E, Alsina A, American Transplant Congress, Philadelphia, PA, 1/2/2015
• Socioeconomic status and surgical outcomes after total pancreatectomy
  Schmidt H, Kilbane EM, Turner AP, House MG, Zyromski NJ, Nakeeb A, Schmidt EP, Americas Hepato-PancreatoBiliary Association Annual Meeting, Miami, FL, 1/19/2014
• Liver transplantation for unresectable intrahepatic cholangiocarcinoma: improved outcomes with neoadjuvant therapy
  Turner AP, Golas A, Johnson MS, Nakeeb A, Pitt HA, House MG, The Society for Surgery of the Alimentary Tract Annual Meeting, Chicago, IL, 1/2/2014
• Rapamycin augments pathogen-specific but not donor-reactive CD8+T Cell responses
  Ferrer IR, Wagener ME, Robertson JM, Turner AP, Kirk AD, Larsen CP, Ford ML, American Transplant Congress, San Diego, CA, 1/1/2010
• Rapamycin enhances the magnitude and quality of viral-specific CD8+ T cell responses to vaccinia virus vaccination in the rhesus macaque
  Turner AP, Shaffer VO, Martens C, Turner PL, Hendrix R, Stempora L, Gangappa S, Kirk AD, Larsen CP, American Transplant Congress, Boston, MA, 1/29/2009
• Distribution of alloreactivity within CD8+ T cell subsets in the rhesus macaque
  Turner AP, Weaver, TA, Stempora L, Iwakoshi N, Ford ML, Kirk AD, Larsen CP, American Transplant Congress, Boston, MA, 1/29/2009
• Total Pancreatectomy and Autologous Islet Transplantation for Chronic Pancreatitis: Long Term Assessment of Graft Function.
  Agarwal A, Avila JG, Turgeon NA, Sears MH, Turner AP, Russell MC, Sarmiento J, Kirk AD, Pearson TC, Larsen CP, American Transplant Congress, Boston, MA, 1/29/2009
• Selective Targeting of Antigen Experienced Memory T Cells with LFA3-Ig: The Role of CD2 Cell Surface Density
  Weaver T, Charafeddine A, Turner AP, Agarwal A, Russell M, Badell I, Stempora L, Larsen C, Kirk A, American Transplant Congress, Boston, MA, 1/29/2009
• Time Profiles of Specific Physiologic and Genetic Parameters of Neonatal Porcine Pancreatic Islets
  Avila JG, Cano JA, Agarwal A, Iwakoshi N, Matar A, Russell MC, Turner AP, Badell IR, Korbutt G, Rayat G, Rajotte RV, Pearson T, Kirk AD, Larsen CP, American Transplant Congress, Boston, MA, 1/29/2009
• Identification of Critical Factors Leading to Successful Islet Isolations and Transplantation
  Avila JG, Agarwal A, Turgeon N, Cano JA, Turner AP, Russell MC, Kirk AD, Pearson T, Larsen CP, American Transplant Congress, Boston, MA, 1/29/2009
• Characterization of the magnitude and quality of response to vaccinia virus vaccination in immunosuppressed rhesus macaques. Poster presentation.
  Turner AP, Shaffer VO, Turner PL, Gangappa S, Larsen CP, American Transplant Congress, Toronto, Canada, 1/31/2008
• Development of a neonatal porcine islet isolation procedure with successful transplantation outcomes
  Avila J, Cano J, Holbrook E, Russell M, Iwakoshi N, Turner AP, Agarwal A, Kirk A, Larsen C, American Transplant Congress, Toronto, Canada, 1/31/2008
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Lectures

• Alefacept improves efficacy of costimulation blockade in nonhuman primate islet allograft survival 
  Philadelphia, PA - 1/30/2011
• LFA-3-Ig (alefacept) prolongs allograft survival by targeting costimulation blockade resistant T effector memory (TEM) cells in non-human primate islet transplantation 
  Boston, MA - 1/29/2009
• A Novel Anti-LFA-1-Based Therapy Enhances Allogeneic Islet Survival and Function in Nonhuman Primates 
  Boston, MA - 1/29/2009
• A novel calcineurin inhibitor and sirolimus-free antiLFA-1-based therapy enhances allogeneic islet survival and function in nonhuman primates 
  Chicago, IL - 1/11/2009
• A novel calcineurin inhibitor- and sirolimus-free anti-LFA-1-based therapy enhances allogeneic islet survival and function in nonhuman primates 
  1/1/2009
• A novel costimulation blockade regimen for engraftment and function of allogeneic islets in diabetic rhesus macaques 
  Toronto, Canada - 1/31/2008
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