AlexanderLauMD

PubMed

• 40 citations
  TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca 2+
  Brian M. Woolums, Brett A. McCray, Hyun Sung, Masashi Tabuchi, Jeremy M. Sullivan
  Nature Communications. 2020-05-29
• 25 citations
  Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension.
  Brett A. McCray, Erika Diehl, Jeremy M. Sullivan, William H. Aisenberg, Nicholas W. Zaccor
  Nature Communications. 2021-03-04
• 5 citations
  A Central Role for Lipocalin-2 in the Adaptation to Short-Bowel Syndrome Through Down-Regulation of IL22 in Mice.
  Ailan Zhang, Chhinder P. Sodhi, Menghan Wang, Darla R. Shores, William B. Fulton
  Cellular and Molecular Gastroenterology and Hepatology. 2020-01-01

Abstracts/Posters

• Generating a TRPV4 neuropathy patient database to facilitate clinical trial readiness
  McCray, B. A., Peyton, M., Stewart, S., Lau, A. R., Sumner, C. J.., 2021 Peripheral Nerve Society virtual event, 6/2021
• Neuropathy-Causing TRPV4 Mutations Disrupt TRPV4-RhoA Interactions and Impair Cytoskeletal Regulation
  McCray, B. A., Diehl, E., Sullivan, J. M., Aisenberg, W. H., Lau, A. R., Rich, D. J., Hellmich, U. A., Lloyd, T. E., & Sumner, C. J.., 145th Annual Meeting American Neurological Association, 10/2020
• Neuropathy-causing mutations in TRPV4 disrupt interaction with RhoA and impair cytoskeletal regulation
  McCray, B. A., Sullivan, J. M., Aisenberg, W. H., Diehl, E., Lau, A. R., Hellmich, U. A., Lloyd, T. E., & Sumner, C. J.., 2020 Peripheral Nerve Society Virtual Event, 6/2020
• Lipocalin-2 Inhibits Interleukin-22 Expression and Reduces Intestinal Adaptation in a Mouse Model of Short Bowel Syndrome
  Zhang, A., Lu, P., Zhou, Q., Wang, M., Prindle, T., Jia, H., Lau, A. R., & Alaish, S. M. ., Journal of the American College of Surgeons, 10/1/2019
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