AlexanderKushnirMDPhD

PubMed

• 138 citations
  Mechanism of adrenergic Ca V 1.2 stimulation revealed by proximity proteomics
  Guoxia Liu, Arianne Papa, Alexander Katchman, Sergey I. Zakharov, Daniel Roybal
  Nature. 2020-01-22
• 7 citations
  Outcomes of posterior wall isolation with pulmonary vein isolation for paroxysmal atrial fibrillation.
  Lior Jankelson, Leonid Garber, Eric Shulman, Roi Bar Cohen, Connor Peterson
  Journal of Cardiovascular Electrophysiology. 2022-02-01
• 105 citations
  Intracellular calcium leak in heart failure and atrial fibrillation: a unifying mechanism and therapeutic target
  Haikel Dridi, Alexander Kushnir, Ran Zalk, Qi Yuan, Zephan Melville
  Nature Reviews. Cardiology. 2020-06-18

Journal Articles

• High-density substrate and activation mapping of epicardial ventricular tachycardia during left ventricular assist device implant  
  Alexander Kushnir, MD, PhD Kristin H. Pallister, MS Salma B. Chaudhary, MD Marisa Cevasco, MD Yoshifumi Naka, MD Deepak Saluja, MD, FHRS, Heart Rhythm Case Reports, 7/3/2020
• Ryanodine receptor dysfunction in human disorders  
  Kushnir A, Wajsberg B, Marks AR, Biochim Biophys Acta., 1/21/2018
• Cardiac CaV12 channels require Beta subunits for Beta-adrenergicmediated modulation but not trafficking  
  Yang L*, Katchman A*, Kushner JS*, Kushnir A*, Zakharov SI, Chen BX, Shuja Z, Subramanyam P, Liu G, Papa A, Roybal DD, Pitt GS, Colecraft HM, Marx SO. *contributed equ..., J Clin Invest., 1/13/2018
• Ryanodine Receptor Calcium Leak in Circulating B-lymphocytes as a Biomarker in Heart Failure  
  Kushnir A, Santulli G, Reiken SR, Sokol S, Kitsis RN, Marks AR, Circulation, 1/1/2018
• Giant Cell Arteritis as a Cause of Myocarditis and Atrial Fibrillation  
  Kushnir A, Restaino SW, Yuzefpolskaya M, Circ Heart Fail., 1/1/2016
• Ryanodine Receptor Patents  
  Kushnir A, Marks AR, Recent Pat Biotechnol., 1/1/2012
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  Kushnir A, Betzenhauser MJ, Shan J, Reiken S, Marks AR, PNAS, 1/1/2010
• Phosphorylation of the Ryanodine Receptor Mediates the Cardiac Fight or Flight Response in Mice  
  Shan J*, Kushnir A*, Betzenhauser MJ*, Reiken S*, Li J, Lehnart S, Lindegger N, Mongillo M, Mohler P, Marks AR, *contributed equally, J Clin Invest., 1/1/2010
• Role of Chronic Ryanodine Receptor Phosphorylation in Heart Failure and b-adrenergic Receptor Blockade in Mice  
  Shan J*, Betzenhauser MJ*, Kushnir A*, Reiken S*, Meli AC, Wronska A, Dura M, Chen BX, Marks AR, *contributed equally, J Clin Invest., 1/1/2010
• The Ryanodine Receptor in Cardiac Physiology and Disease  
  Kushnir A, Marks AR, Adv Pharmacol., 1/1/2010
• Ryanodine receptor studies using genetically engineered mice  
  Kushnir A, Betzenhauser MJ, Marks AR, FEBS Letters, 1/1/2010
• Cardiac ryanodine receptor function and regulation in heart disease  
  Lehnart SE, Wehrens XH, Kushnir A, Marks AR, Ann N Y Acad Sci, 1/1/2004
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Books/Book Chapters

• Cardiac Electrophysiology: From Cell to Bedside 
  Chapter: Voltage-gated Calcium Channels. 
  Kushnir A, Marx SOEditors: Zipes D, Jalife J.ElsevierEdition 7th,2017
• Ryanodine Receptors: Structure, Function, and Dysfunction in Clinical Disease 
  Chapter: Evolution of the Ryanodine Receptor Gene Family. 
  Page 1 - 8Kushnir A, Mollah AKMM, Wehrens XHTEditors: XHT. Wehrens & A. Marks.Springer, New York2004

Lectures

• RYR1 database: integrating clinical data, crystal structure and physiology 
  Pittsburgh, PA - 1/1/2018
• Novel Approach to Modeling Pathogenicity of CPVT Mutations 
  Boston, MA - 1/1/2018
• RYR database: integrating clinical data, cryo-EM structure and physiology 
  Beer-sheva, Israel - 1/1/2018