AlexanderKhorutsMD

Professor, Medicine, University of Minnesota Medical School

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Office
2635 University Ave W
Ste 100
Saint Paul, MN 55114
Phone+1 612-871-1145

Fax+1 612-870-5491

Dr. Alexander Khoruts is a Gastroenterologist based in Minneapolis, MN. He received his MD from the University of Minnesota Medical School in 1989 and later completed both his residency in Internal Medicine and fellowship in Gastroenterology at the same institution. His research contributions are largely in the field of 'fecal microbiota transplantation', a term that he coined in 2011 along with a group of physicians in the field. His research produced several seminal works, including first documentation of donor microbiota engraftment in a patient (2010) and development of a standardized protocol for manufacturing donor microbiota for transplantation (published in 2012). His team developed multiple formulations of donor microbiota, including encapsulated freeze-dried preparation that is being tested in in clinical trials for a multitude of indications. These include inflammatory bowel diseases, optimization of cancer therapies, food allergies, hepatic encephalopathy, autism, and others.

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Interventional Bioremediation of Microbiota in Metabolic Syndrome Start of enrollment: 2016 Jun 01
Terminated
Phase 2
Dietary Optimization of Microbiome Recovery Following Fecal Microbiota Transplantation Start of enrollment: 2023 May 01
Recruiting
Not Applicable
Roles: Contact, Principal Investigator

PubMed

Journal Articles

Amphiregulin in Intestinal Acute Graft-Versus-Host Disease: A Possible Diagnostic and Prognostic Aid
Brittney Schultz, Bruce R Blazar, Daniel J Weisdorf, Shernan G Holtan, Alexander Khoruts, Armin Rashidi, Margaret L MacMillan, Khalid Amin, Byron P Vaughn, Nature
CLOUD: A Non-Parametric Detection Test for Microbiome Outliers
Alexander Khoruts, Kimberly Viskocil, BioMed Central

Abstracts/Posters

Pre-Transplant Serum Claudin-3 Predicts Intestinal Graft-Versus-Host Disease and Non-Relapse Mortality Risk after Allogeneic Hematopoietic Cell Transplantation
Alexander Khoruts, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019

New Clinical Study Is Analyzing How Gut Microbe Transplants Could Help Curb Alcohol UseFebruary 9th, 2023
FMT in IBS: ‘We’ve Been Targeting the Wrong Part of the Intestine’October 18th, 2022
Positive Results with Faecal Microbiota Therapy for Patients with Peanut AllergiesFebruary 28th, 2022
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Identification Of Intestinal Bacteria Protective Against C. Difficile ColitisNational Institute Of Allergy And Infectious Diseases2011–2012
Translational Control Of Regulatory T Cell InductionNational Institute Of Allergy And Infectious Diseases2009–2010
Behavior Of Regularity CD25+ CD4 T Cells In VivoNational Institute Of Diabetes And Digestive And Kidney Diseases2004–2007
Behavior Of Regulatory CD25+ CD4 T Cells In VivoNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2007
Maintenance Of Oral Tolerance By CD4+ T Cells In VivoNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2002