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Office
2635 University Ave W
Ste 100
Saint Paul, MN 55114Phone+1 612-871-1145Fax+1 612-870-5491
Summary
- Dr. Alexander Khoruts is a Gastroenterologist based in Minneapolis, MN. He received his MD from the University of Minnesota Medical School in 1989 and later completed both his residency in Internal Medicine and fellowship in Gastroenterology at the same institution. His research contributions are largely in the field of 'fecal microbiota transplantation', a term that he coined in 2011 along with a group of physicians in the field. His research produced several seminal works, including first documentation of donor microbiota engraftment in a patient (2010) and development of a standardized protocol for manufacturing donor microbiota for transplantation (published in 2012). His team developed multiple formulations of donor microbiota, including encapsulated freeze-dried preparation that is being tested in in clinical trials for a multitude of indications. These include inflammatory bowel diseases, optimization of cancer therapies, food allergies, hepatic encephalopathy, autism, and others.
Education & Training
- University of MinnesotaFellowship, Gastroenterology, 1992 - 1996
- University of MinnesotaResidency, Internal Medicine, 1989 - 1992
- University of Minnesota Medical SchoolClass of 1989
Certifications & Licensure
- MN State Medical License 1992 - 2025
- American Board of Internal Medicine Gastroenterology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
Clinical Trials
- Interventional Bioremediation of Microbiota in Metabolic Syndrome Start of enrollment: 2016 Jun 01
- Dietary Optimization of Microbiome Recovery Following Fecal Microbiota Transplantation Start of enrollment: 2023 May 01
Roles: Contact, Principal Investigator
Publications & Presentations
PubMed
- Diagnosis and Management of Clostridioides difficile in Inflammatory Bowel Disease.Byron P Vaughn, Alexander Khoruts, Monika Fischer
The American Journal of Gastroenterology. 2025-02-01 - Fecal microbiota transplantation to prevent acute graft-versus-host disease: pre-planned interim analysis of donor effect.Swetha Reddi, Liliia Senyshyn, Maryam Ebadi, Daniel Podlesny, Samuel S Minot
Nature Communications. 2025-01-25 - Microbiota transplant for hepatic encephalopathy in cirrhosis: The THEMATIC trial.Jasmohan S Bajaj, Andrew Fagan, Edith A Gavis, Richard K Sterling, Mary Leslie Gallagher
Journal of Hepatology. 2025-01-10
Journal Articles
- Amphiregulin in Intestinal Acute Graft-Versus-Host Disease: A Possible Diagnostic and Prognostic AidBrittney Schultz, Bruce R Blazar, Daniel J Weisdorf, Shernan G Holtan, Alexander Khoruts, Armin Rashidi, Margaret L MacMillan, Khalid Amin, Byron P Vaughn, Nature
- CLOUD: A Non-Parametric Detection Test for Microbiome OutliersAlexander Khoruts, Kimberly Viskocil, BioMed Central
Press Mentions
- Could Fecal Microbiota Transplantation Help Patients Heal After Stem Cell Transplantation?January 28th, 2025
- New Clinical Study Is Analyzing How Gut Microbe Transplants Could Help Curb Alcohol UseFebruary 9th, 2023
- FMT in IBS: ‘We’ve Been Targeting the Wrong Part of the Intestine’October 18th, 2022
- Join now to see all
Grant Support
- Identification Of Intestinal Bacteria Protective Against C. Difficile ColitisNational Institute Of Allergy And Infectious Diseases2011–2012
- Translational Control Of Regulatory T Cell InductionNational Institute Of Allergy And Infectious Diseases2009–2010
- Behavior Of Regularity CD25+ CD4 T Cells In VivoNational Institute Of Diabetes And Digestive And Kidney Diseases2004–2007
- Behavior Of Regulatory CD25+ CD4 T Cells In VivoNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2007
- Maintenance Of Oral Tolerance By CD4+ T Cells In VivoNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2002
Other Languages
- Russian
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