Alexander Hughes MD

PubMed

• Endplate Degeneration and Intervertebral Vacuum Phenomenon Are Positively Correlated: A Retrospective Study in Patients Undergoing Lumbar Fusion Surgery.
  Gaston Camino-Willhuber, Lukas Schönnagel, Erika Chiapparelli, Paul Kohli, Krizia Amoroso
  Clinical Spine Surgery. 2025-04-01
• What is the Association of the Subsections of the Oswestry Disability Index and Overall Improvement 2 Years After Lumbar Surgery for Degenerative Lumbar Spondylolisthe...
  Jan Hambrecht, Paul Köhli, Roland Duculan, Ranqing Lan, Erika Chiapparelli
  Spine. 2025-04-01
• The Association Between Preoperative Cannabis Use and Anxiety, Pain Scores and Opioid Consumption in Patients Undergoing Spinal Fusion: A Retrospective Cohort Study.
  Krizia Amoroso, Erika Chiapparelli, Jiaqi Zhu, Ali E Guven, Jennifer Shue
  Global Spine Journal. 2025-03-15

Journal Articles

• Lower Spine Volumetric Bone Density in Patients with a History of Epidural Steroid Injections  
  Alexander P Hughes, Richard S Bockman, Emily M Stein, Tariq Chukir, Joel M Press, John A Carrino, The Journal of Clinical Endocrinology and Metabolism
• "Multivariate Analysis on Risk Factors for Post-operative Ileus After Lateral Lumbar Interbody Fusion"  
  Al Maaieh MA, Du JY, Aichmair A, Huang RC, Hughes AP, Cammisa FP, Girardi FP, Sama AA, Spine, 1/15/2014
• "Microdiscectomy for the Treatment of Lumbar Disc Herniation: An Evaluation of Reoperations and Long-term Outcomes"  
  Aichmair A, Du JY, Shue J, Evangelisti G, Sama AA, Hughes AP, Lebl DR, Burket JC, Cammisa FP, Girardi FP, Evid Based Spine Care J, 1/1/2014
• "Determinants of Evolution Of Endplate and Disc Degeneration in the Lumbar Spine: A Multifactorial Perspective"  
  arshad-Amacker NA, Hughes AP, Aichmair A, Herzog RJ, Farshad M, Eur Spine J, 1/1/2014
• "Nerve injury after lateral lumbar interbody fusion: a review of 919 treated levels with identification of risk factors"  
  Lykissas MG, Aichmair A, Hughes AP, Sama AA, Lebl DR, Taher F, Du JY, Cammisa FP, Girardi FP, Spine J, 1/1/2014
• "C1-C2 instability with severe occipital headache in the setting of vertebral artery facet complex erosion"  
  Taher F, Bokums K, Aichmair A, Hughes AP, Eur Spine J, 1/1/2014
• "Multiple Myeloma Exacerbation following Utilization of Bone Morphogenetic Protein-2 in Lateral Lumbar Interbody Fusion-A Case Report and Review of the Literature"  
  Hughes AP, Taher F, Farshad M, Aichmair A, Spine J, 1/1/2014
• "Is an annular tear a predictor for accelerated disc degeneration?"  
  Farshad-Amacker NA, Hughes AP, Aichmair A, Herzog RJ, Farshad M, Eur Spine J, 1/1/2014
• "Rate of Revision Surgery Following Standalone Lateral Lumbar Interbody Fusion for Lumbar Spinal Stenosis"  
  Nemani VM, Aichmair A, Taher F, Lebl DR, Hughes AP, Sama AA, Cammisa FP, Girardi FP, Spine, 1/1/2014
• "Association between Hounsfield Units and Success of Lumbar Spine Fusion"  
  Schreiber JJ, Taher F, Hughes AP, Girardi FP, HSS J, 1/1/2014
• "Nerve injury and recovery after lateral lumbar interbody fusion with and without bone morphogenetic protein-2 augmentation: A cohort controlled study"  
  Lykissas MG, Aichmair A, Sama AA, Hughes AP, Lebl DR, Taher F, Cammisa FP, Girardi FP, Spine J, 1/1/2014
• "2013 Young Investigator Award Winner: How Safe is Lateral Lumbar Interbody Fusion For the Surgeon? A Prospective In Vivo Radiation Exposure Study"  
  Taher F, Hughes AP, Sama AA, Zeldin R, Schneider R, Holodny EI, Lebl DR, Fantini GA, Nguyen J, Cammisa FP, Girardi FP, Spine, 1/15/2013
• "Contralateral Motor Deficits Following Lateral Lumbar Interbody Fusion"  
  Taher F, Hughes AP, Lebl DR, Sama AA, Pumberger M, Aichmair A, Huang RC, Cammisa FP, Girardi FP, Spine, 1/15/2013
• "Associations between Lumbosacral Transitional Anatomy Types and Degeneration at the Transitional and Adjacent Segments"  
  Farshad-Amacker NA, Herzog RJ, Hughes AP, Aichmair A, Farshad M, Spine J, 1/8/2013
• "Thrombophilic Abnormalities in Patients With or Without Pulmonary Embolism Following Elective Spinal Surgery"  
  Kotwal S, Kawaguchi S, Hughes A , Cammisa Jr. F, Zhang K , Salvati E, Girardi F, HSS Journal, 1/1/2013
• "A Reliable Measurement For Identifying a Lumbosacral Transitional Vertebra With a Solid Bony Bridge on a Single-Slice Midsagittal MRI or Plain Lateral Radiograph"  
  Farshad M, Aichmair A, Hughes AP, Herzog RJ, Farshad-Amacker NA, Bone Joint J, 1/1/2013
• "An Institutional Six-year Trend Analysis of the Neurological Outcome After Lateral Lumbar Interbody Fusion: A 6-Year Trend Analysis of a Single Institution"  
  Aichmair A, Lykissas MG, Girardi FP, Sama AA, Lebl DR, Taher F, Cammisa FP, Hughes AP, Spine, 1/1/2013
• "Symptomatic Heterotopic Bone Formation After rhBMP-2 Utilization in Lateral Lumbar Interbody Fusion"  
  Aichmair A, Girardi FF, Hughes AP, Sama AA, Lebl DR, Cammisa FP, Spine J, 1/1/2013
• "Development and testing of patient lumbar spine surgery expectations survey"  
  Mancuso CA, Cammisa FP, Sama AA, Hughes AP, Ghomrawi HMK, Girardi FP, J Bone Joint Surg Am, 1/1/2013
• "Is There any Relation Between the Amount of Curve Correction and Postoperative Neurologic Deficit or Pain in Patients Undergoing Standalone Lateral Lumbar Interbody F...  
  Lykissas MG, Cho W, Aichmair A, Sama AA, Hughes AP, Lebl DR, Du JY, Cammisa FP Jr, Girardi FP, Spine, 1/1/2013
• "Clinical Predictors of Surgical Outcome in Cervical Spondylotic Myelopathy: An Analysis of 248 Patients"  
  Pumberger M, Froemel D, Aichmair A, Hughes AP, Sama AA, Cammisa FP Jr, Girardi FP, Bone Joint J, 1/1/2013
• "An Analysis of the Safety of Epidural and Spinal Regional Anesthesia in Over 100,000 Consecutive Major Lower Extremity Joint Replacements"  
  Pumberger M, Memtsoudis SG, Stundner O, Herzog R., Boettner F, Hughes AP, Reg Anesth Pain Med, 1/1/2013
• "Development of an Expectations Survey for Patients Undergoing Cervical Spine Surgery"  
  Mancuso CA, Cammisa FP, Sama AA, Hughes AP, Girardi FP, Spine, 1/1/2013
• "Contralateral Psoas Seroma After Transpsoas Lumbar Interbody Fusion with Bone Morphogenetic Protein-2 Implantation"  
  Taher F, Lebl DR, Hughes AP, Girardi FP, Spine J, 1/1/2013
• "Long-term Sequelae of Patients with Retained Drains in Spine Surgery"  
  Gausden EB, Sama AA, Taher F, Pumberger M, Cammisa FP, Hughes AP, J Spinal Disord Tech, 1/24/2012
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Books/Book Chapters

• Master Techniques in Orthopedic Surgery-The Spine 
  Chapter: "Lumbar Disc Arthroplasty" 
  Lebl DR, Girardi FP, Hughes A, Cammisa FPEditors: Thomas Zdeblick & Todd Albert.Lippincott Williams & WilkinsEdition 3rd,2014
• Surgical Management of Low Back Pain 
  Chapter: Bone Biology and Lumbar Fusion 
  Holly LT, Hughes AEditors: Daniel K Resnick; Regis W Haid; Jeffrey C Wang.Thieme; American Association of Neurosurgeons, New York; Rolling Meadows, ILEdition 2nd,2009

Abstracts/Posters

• "The Utility of Intraoperative Gram Stain in Revision Spine Surgery"
  Shifflett G, Nwachukwu BU, Bjerke-Kroll B, Koltsov JC, Sama AA, Girardi FP, Cammisa FP, Hughes AP, American Academy of Orthopaedic Surgeons, Las Vegas, NV, 1/1/2015
• "Microbiologic Profile of Infections in Presumed Aseptic Revision Spine Surgery"
  Shifflett G, Bjerke-Kroll B, Nwachukwu BU, Kueper J, Sama AA, Girardi FP, Cammisa FP, Hughes AP, American Academy of Orthopaedic Surgeons, Las Vegas, NV, 1/1/2015
• "Emergent Reintubation After Anterior Cervical Surgery"
  Schroeder J, Girardi FP, Lebl DR, Sama AA, Cammisa FP, Beckman J, Hughes AP, American Academy of Orthopaedic Surgeons, Las Vegas, NV, 1/1/2015
• "Determinants of Evolution of Endplate and Disc Degeneration in the Lumbar Spine: A Multifactorial Perspective"
  Farshad M, Aichmair A, Hughes AP, Herzog RJ, Farshad NA, European Congress of Radiology, Vienna, Austria, 1/1/2014
• "Single-Level Lateral Lumbar Interbody Fusion for the Treatment of Adjacent Segment Disease: A Retrospective Two-Center Study"
  Aichmair A, Alimi M, Hughes AP, Sama AA, Du JY, Hartl R, Cammisa FP Jr., FP Girardi, North American Spine Society, San Francisco, CA, 1/1/2014
• "Lumbar Surgery in Parkinson Disease Patients"
  Schroeder JE, Cammisa FP, Weinstein J, Hughes AP, Sama AA, Girardi FP, 12th Annual AOSNA Fellows Forum, Banff Springs, Alberta, Canada, 1/1/2014
• "Surgical Care for Cervical Myelopathy in Patients with Parkinson's Disease-A Case Control Study"
  Schroeder JE, Sama AA, Hughes AP, Lebl DR, Aichmair A, Cammisa FP, Girardi FP, AAOS Annual Meeting, New Orleans, LA, 1/1/2014
• "Single-level Lateral Lumbar Interbody Fusion for the Treatment of Adjacent Segment Disease: A Retrospective Two-center Study"
  Aichmair A, Alimi M, Hughes AP, Sama AA, Du JY, Hartl R, Burket J, Cammisa FP, Girardi FP, Annual Society of Lateral Access Surgery (SOLAS), Miami, FL, 1/1/2014
• "Non Fusion Lumbar Spine Surgery in Parkinson Disease-A Positive View?"
  Schroeder JE, Sama AA, Hughes AP, Lebl DR, Aichmair A, Cammisa FP, Girardi FP, International Society for the Advancement of Spine Surgery, Miami, FL, 1/1/2014
• "How Much Deformity Correction Can We Obtain by XLIF and Will It Be Affected by Approach Side: Convex Vs. Concave?"
  Cho W, Cammisa FP, Sama AA, Hughes AP, Huang RC, Girardi FP, International Society for the Advancement of Spine Surgery, Miami, FL, 1/1/2014
• "Is an annular tear a predictor for accelerated disc degeneration?"
  Farshad-Amacker NA, Hughes AP, Aichmair A, Herzog RJ, Farshad M, 74th Annual Congress Swiss Society of Orthopedics and Traumatology (SSOT), St. Gallen, Switzerland, 1/1/2014
• "Determinants of Evolution of Endplate and Disc Degeneration in the Lumbar Spine-A Multifactorial Perspective"
  Farshad-Amacker NA, Hughes AP, Aichmair A, Herzog RJ, Farshad M, 74th Annual Congress Swiss Society of Orthopedics and Traumatology (SSOT), St. Gallen, Switzerland, 1/1/2014
• "Lateral Surgery in Deformity Correction"
  Hughes AP, Symposium: Lateral Approach to the Lumbar Spine, North American Spine Society, San Francisco, CA, 1/1/2014
• "Anatomic Guideline for Approach to Lateral Thoraco-Lumbar Interbody Fusion"
  Cho W, Fantini GA, Cammisa FP, Sama AA, Hughes AP, Girardi FP, International Society for the Advancement of Spine Surgery, Miami, FL, 1/1/2014
• "Single-level Lateral Lumbar Interbody Fusion for the Treatment of Adjacent Segment Disease: A Retrospective Two-center Study"
  Aichmair A, Alimi M, Hughes AP, Shue J, Sama AA, Du JY, Härtl R, Cammisa FP, Girardi FP, Lumbar Spine Research Society (LSRS) Annual Meeting, Chicago, IL, 1/1/2014
• "The Role of BMP-2 on Postoperative Fusion and Subsidence Rates after Lateral Lumbar Interbody Fusion: A Cohort Controlled Study"
  Aichmair A, Lykissas MG, Kiely PD, Hughes AP, Sama AA, Lebl DR, Cammisa FP, Girardi FP, International Society for the Study of the Lumbar Spine (ISSLS), Seoul, Korea, 1/1/2014
• "Reoperation Rate After Microdiscectomy for the Treatment of Lumbar Disc Herniation: Long-term Follow-up After an Average of 10.8 Years"
  Aichmair A,  Du JY, Shue J, Evangelisti G, Sama AA, Hughes AP, Lebl DR, Cammisa FP, Girardi FP, International Society for the Study of the Lumbar Spine (ISSLS), Seoul, Korea, 1/1/2014
• "Is an annular tear a predictor for accelerated disc degeneration?"
  Farshad-Amacker NA, Hughes AP, Aichmair A, Herzog RJ, Farshad M, Swiss Congress of Radiology, Montreux, Switzerland, 1/1/2014
• "Early Adjacent Segment Add-On Surgery and End of Construct Revision Surgery After Multilevel Lumbar Lateral Interbody Fusion"
  Farshad M, Farshad-Amacker NA, Aichmair A, Girardi FP, Sama AA, Cammisa FP, Hughes AP, 74th Annual Congress Swiss Society of Orthopedics and Traumatology (SSOT), St. Gallen, Switzerland, 1/1/2014
• "Risk Factors for Implant Subsidence After Stand-Alone Lateral Lumbar Interbody Fusion"
  Essig DA, Cho W, Hughes AP, Huang RC, Sama AA, Girardi FP, Cammisa FP Jr, North American Spine Society, San Francisco, CA, 1/1/2014
• "How Much Deformity Correction Can We Obtain by LLIF and Will It Be Affected by Approach Side: Convex Versus Concave?"
  Cho W, Castro CA, Cammisa FP Jr., Sama AA, Hughes AP, Huang RC, Girardi FP, North American Spine Society, San Francisco, CA, 1/1/2014
• "Lumbar Surgery in Parkinson Disease Patients"
  Schroeder JE, Cammisa FP Jr., Sama AA, Kaplan L, Hughes AP, Lebl DR, Girardi FP, North American Spine Society, San Francisco, CA, 1/1/2014
• Pumberger M, Memtsoudis SG, Stundner O, Herzog R., Boettner F, Hughes AP, The European Anaesthesiology Congress, Barcelona, Spain, 1/1/2013
• "Development and Testing of a Patient Cervical Spine Surgery Expectations Survey"
  Mancuso CA, Cammisa FP, Sama AA, Hughes AP, Girardi FP, AAOS Annual Meeting, Chicago, IL, 1/1/2013
• "Retropleural Exposure of T12-L1 and L1-L2 Disk Spaces during Lateral Thoracolumbar Interbody Fusion: Surgical Technique"
  Fantini GA, Girardi FP, Sama AA, Hughes AP, Cammisa FP, International Society for the Advancement of Spine Surgery (ISASS), Vancouver, Canada, 1/1/2013
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Lectures

• "Anterior Techniques" 
  The Hospital for Special Surgery, New York, NY - 1/1/2013
• "Adult: Scoliosis: Selective Treatment" 
  DePuy Spine Institute, Miami, FL - 1/1/2013
• "Selective Fusion: XLIF" 
  The Hospital for Special Surgery, New York, NY - 1/1/2013
• "Spinal Infection and Spondyloarthropathies" 
  The Hospital for Special Surgery, New York, NY - 1/1/2012
• HSS Radiology Grand Rounds: "New Imaging Needs in Spinal Surgery: C-TDR and LLIF" 
  The Hospital for Special Surgery, New York, NY - 1/1/2011
• "Anatomic Considerations in Lateral Access Lumbar Surgery." 
  New York, NY - 1/1/2011
• "How to Integrate Transpsoas Surgery into Your Practice" 
  Weill Cornell Medical College, New York, NY - 1/1/2011
• "Evidence Based Medicine in Spinal Surgery" 
  The Hospital for Special Surgery, New York, NY - 1/1/2010
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Other

• "Validating How X-Rays and MRIs Could Help Predict CSM Severity and Surgical Outcomes" 
  Girardi FP, Hughes AP, Sama AA, Cammisa FP, Lebl DR, Hospital for Special Surgery eNewsletter
  1/1/2013
• "Spinal Tumors." 
  Sama AA, Girardi FP, Cammisa FP, Lebl DR, Hughes A, eMedicine from WebMD
  1/17/2012
• "Don't Slow Down to Save Your Back. Exercise, Instead!" 
  Alexander P. Hughes, MD, Men's Health
  1/24/2011