AlexA.AdjeiMDPhD, FACP, FASCO

Clinical Trials

• Combination Chemotherapy With Suramin Plus Doxorubicin in Treating Patients With Advanced Solid Tumors Start of enrollment: 1997 Oct 01

  Completed

  Phase 1

• Irinotecan With Docetaxel in Treating Patients With Recurrent or Metastatic Non-small Cell Lung Cancer Start of enrollment: 1999 Oct 01

  Completed

  Phase 2

• LY231514 Plus Gemcitabine in Treating Women With Metastatic Breast Cancer Start of enrollment: 2000 Dec 01

  Completed

  Phase 2

• PS-341 in Treating Patients With Advanced Cancer Start of enrollment: 1999 Nov 01

  Completed

  Phase 1

• Pemetrexed Disodium Plus Gemcitabine in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Start of enrollment: 2001 Aug 01

  Completed

  Phase 2

• PS-341 and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors Start of enrollment: 2001 Dec 01

  Completed

  Phase 1

• Imatinib Mesylate in Treating Patients With Recurrent Small Cell Lung Cancer Start of enrollment: 2003 May 01

  Completed

  Phase 2

• Tipifarnib, Gemcitabine, and Cisplatin in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Start of enrollment: 2003 Oct 01

  Completed

  Phase 2

• CCI-779 in Treating Patients With Stage IIIB (With Pleural Effusion) or Stage IV Non-Small Cell Lung Cancer Start of enrollment: 2004 Feb 01

  Completed

  Phase 2

• Bortezomib, Paclitaxel, Carboplatin and Radiation Therapy for Non-Small Cell Lung Cancer Start of enrollment: 2004 Sep 01

  Completed

  Phase 1, Phase 2

• Sorafenib in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer Start of enrollment: 2004 Dec 01

  Completed

  Phase 2

• Pemetrexed Disodium and Bevacizumab in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Start of enrollment: 2006 May 01

  Completed

  Phase 2

• Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-small Cell Lung Cancer That Was Removed By Surgery Start of enrollment: 2007 Jun 01

  Active, not recruiting

  Phase 3

• Gemcitabine and Carboplatin With or Without AZD2171 as First-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer Start of enrollment: 2007 Jun 01

  Completed

  Phase 2

• Pemetrexed Disodium With or Without Sorafenib as Second-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer Start of enrollment: 2007 Sep 01

  Completed

  Phase 2

• High-Dose or Standard-Dose Radiation Therapy and Chemotherapy With or Without Cetuximab in Treating Patients With Newly Diagnosed Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery Start of enrollment: 2007 Nov 01

  Completed

  Phase 3

• KX2-391 in Treating Patients With Advanced Solid Tumors or Lymphoma That Did Not Respond to Treatment Start of enrollment: 2007 Oct 01

  Completed

  Phase 1

• Calcitriol in Preventing Lung Cancer in Smokers and Former Smokers at High Risk of Lung Cancer Start of enrollment: 2008 Jul 17

  Completed

  Not Applicable

• Pemetrexed Disodium or Erlotinib Hydrochloride as Second-Line Therapy in Treating Patients With Advanced Non-small Cell Lung Cancer Start of enrollment: 2008 Oct 01

  Terminated

  Phase 3

• A Phase 2 Exploratory Study of Erlotinib and SNDX-275 in Participants With Non-small Cell Lung Carcinoma Who Are Progressing on Erlotinib Start of enrollment: 2008 Aug 01

  Terminated

  Phase 2

• Radiation Therapy or Observation After Chemotherapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer Start of enrollment: 2008 Oct 01

  Terminated

  Phase 2

• Dose Escalation Safety Study of TL32711 in Adults With Refractory Solid Tumors or Lymphoma Start of enrollment: 2009 Nov 01

  Completed

  Phase 1

• Entinostat and Sorafenib Tosylate in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory or Relapsed Acute Myeloid Leukemia Start of enrollment: 2010 Jun 01

  Terminated

  Phase 1

• Dose Escalation, Combination Chemotherapy Safety Study of Birinapant (TL32711), in Subjects With Advanced or Metastatic Solid Tumors Start of enrollment: 2010 Oct 01

  Completed

  Phase 1, Phase 2

• Safety Study of the Drug MM-151 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment Start of enrollment: 2012 Jan 01

  Completed

  Phase 1

• Entolimod in Treating Patients With Locally Advanced or Metastatic Solid Tumors That Cannot Be Removed By Surgery Start of enrollment: 2012 Jan 01

  Completed

  Phase 1

• PI3K Inhibitor BKM120 and Docetaxel in Treating Patients With Advanced Solid Tumor That is Locally Advanced, Cannot Be Removed By Surgery, or Metastatic Start of enrollment: 2012 May 01

  Completed

  Phase 1

• Deuterated Phenanthrene Tetraol in Smokers Who Are at High Risk For Lung Cancer Start of enrollment: 2012 Jul 01

  Completed

• Pegylated Irinotecan NKTR 102 in Treating Patients With Relapsed Small Cell Lung Cancer Start of enrollment: 2013 Aug 29

  Completed

  Phase 2

• A Pilot Study of Oral Calcitriol in Patients at High Risk for Lung Cancer Start of enrollment: 2008 Jul 01
• Nintedanib in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Failed Up to Two Previous Chemotherapy Regimens Start of enrollment: 2014 Jan 30

  Completed

  Phase 2

• Buparlisib, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Advanced Solid Tumors Start of enrollment: 2015 Sep 01

  Withdrawn

  Phase 1

• Icotinib Hydrochloride in Treating Patients With Advanced Cancers Start of enrollment: 2014 Aug 01

  Withdrawn

  Phase 1

• Introduction of Eurartesim® in Burkina Faso, Mozambique, Ghana and Tanzania Start of enrollment: 2013 Sep 01

  Unknown status

• Study of Oral cMET Inhibitor INC280 in Patients With EGFR Wild-type (wt), Advanced Non-small Cell Lung Cancer (NSCLC) (Geometry Mono-1) Start of enrollment: 2015 Jun 11

  Completed

  Phase 2

• Nintedanib Compared With Placebo in Treating Against Radiation-Induced Pneumonitis in Patients With Non-small Cell Lung Cancer That Cannot Be Removed by Surgery and Are Undergoing Chemoradiation Therapy Start of enrollment: 2015 Jun 29

  Terminated

  Phase 2

• Ribociclib and Gemcitabine Hydrochloride in Treating Patients With Advanced or Metastatic Solid Tumors Start of enrollment: 2018 Jan 04

  Completed

  Phase 1

• Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer Start of enrollment: 2018 Aug 10

  Terminated

  Phase 1

• Ph I/II Trial of Systemic VSV-IFNβ-NIS in Combination With Checkpoint Inhibitor Therapy in Patients With Select Solid Tumors Start of enrollment: 2019 Apr 09

  Recruiting

  Phase 1, Phase 2

• Study of TJ011133 in Participants With Relapsed/Refractory Advanced Solid Tumors and Lymphoma Start of enrollment: 2019 Apr 16

  Completed

  Phase 1

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