AlessandroSantinMD

Obstetrics & Gynecology • New Haven, CT

Professor, Obstetrics & Gynecology, Yale University School of Medicine

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Office
20 York St
New Haven, CT 06510
Phone+1 203-737-4450

Fax+1 203-737-4339

Education & Training

Yale School of MedicineClass of 1989

Certifications & Licensure

AR State Medical License 1998 - 2026
CT State Medical License 2007 - 2025

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2010-2014
Top Doctors: New York Metro Area Castle Connolly, 2010-2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
America's Top Doctors for Cancer Castle Connolly, 2009-2013
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Clinical Trials

Evaluation of Carboplatin/Paclitaxel With and Without Trastuzumab (Herceptin) in Uterine Serous Cancer Start of enrollment: 2011 Jun 01
Completed
Phase 2
Nivolumab in Treating Patients With Persistent, Recurrent, or Metastatic Cervical Cancer Start of enrollment: 2015 May 18
Active, not recruiting
Phase 2
A Phase II Evaluation of Afatinibin Patients With Persistent or Recurrent HER2-positive Uterine Serous Carcinoma Start of enrollment: 2015 Jun 01
Recruiting
Phase 2
Copanlisib in Treating Patients With Persistent or Recurrent Endometrial Cancer Start of enrollment: 2016 Sep 16
Completed
Phase 2
Evaluation of Weekly Ixabepilone With or Without Biweekly Bevacizumab Start of enrollment: 2017 Apr 03
Completed
Phase 2
Evaluation of Mirvetuximab Soravtansine (IMGN853) in Women With Folate Receptor-α Positive Endometrial Cancer Start of enrollment: 2020 Jul 15
Recruiting
Phase 2
A Study of Sacituzumab Govitecan (IMMU-132) in Endometrial Carcinoma Start of enrollment: 2020 Mar 17
Recruiting
Phase 2
Roles: Contact, Principal Investigator, Sponsor-Investigator
Treatment of High-Grade Pre-Neoplastic Cervical Lesions (CIN 2/3) Start of enrollment: 2016 Jul 01
Completed
Phase 2
Roles: Contact, Principal Investigator
A Study of Sacituzumab Govitecan (IMMU-132) in Platinum-resistant Ovarian Cancer Patients Start of enrollment: 2024 Jan 08
Recruiting
Phase 2
Roles: Principal Investigator, Sponsor-Investigator, Contact
A Study of Sacituzumab Govitecan (IMMU-132) in Patients With Recurrent or Persistent Cervical Cancer Start of enrollment: 2023 Jun 02
Recruiting
Phase 2
Roles: Sponsor-Investigator, Principal Investigator, Contact
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Publications & Presentations

PubMed

Utility of next generation sequencing to unequivocally establish clonality in synchronous vs metastatic endometrial and ovarian carcinomas.
Michelle Greenman, Stefania Bellone, Tobias Hartwich, Natalia Buza, Alessandro D Santin
Gynecologic Oncology Reports. 2024-12-01
1 citations
Efficacy and Safety of Sacituzumab Govitecan in Patients With Advanced Solid Tumors (TROPiCS-03): Analysis in Patients With Advanced Endometrial Cancer.
Alessandro D Santin, Bradley R Corr, Alexander Spira, Lyndsay Willmott, James Butrynski
Journal of Clinical Oncology. 2024-10-10
Preclinical activity of datopotamab deruxtecan, a novel TROP2 directed antibody-drug conjugate targeting trophoblast cell-surface antigen 2 (TROP2) in ovarian carcinoma.
Blair McNamara, Michelle Greenman, Stefania Bellone, Luca A Santin, Cem Demirkiran
Gynecologic Oncology. 2024-10-01

Journal Articles

Phase II Evaluation of Nivolumab in the Treatment of Persistent or Recurrent Cervical Cancer (NCT02257528/NRG-GY002)
Alessandro D Santin, Michael Frumovitz, Natalia Buza, Samir Khleif, Elena S Ratner, Roisin E O'Cearbhaill, Michael Birrer, Gynecologic Oncology

Lectures

A phase II evaluation of nivolumab, a fully human antibody against PD-1, in the treatment of persistent or recurrent cervical cancer.
2018 ASCO Annual Meeting - Chicago, Illinois - 06/4/2018

Press Mentions

Sacituzumab Govitecan Shows Promise in Advanced Endometrial CancerAugust 15th, 2024
2023 ‘Top Doctors’ List Features Over 250 Yale Medicine PhysiciansMay 3rd, 2023
Connecticut Magazine’s 2023 “Top Doctors” Issue Recognizes 82 Smilow Cancer Hospital and Yale Cancer Center PhysiciansMay 1st, 2023
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Professional Memberships

American Society of Clinical Oncology - ASCO
Member