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Office
University of Pennsylvania, 3400 Civic Center Blvd.
1-Perelman South
Philadelphia, PA 19104Phone+1 215-662-7610Fax+1 215-615-4966
Summary
- Dr. Alain Rook is a dermatologist in Philadelphia, PA and is affiliated with Hospital of the University of Pennsylvania. He received his medical degree from University of Michigan Medical School and has been in practice 42 years. He is experienced in general dermatology, cryosurgery, phototherapy, and complex medical dermatology. He has more than 300 publications and over 500 citings.
Education & Training
- University of Pennsylvania Health SystemResidency, Dermatology, 1986 - 1989
- National Institutes of Health Clinical CenterFellowship, Allergy and Immunology, 1984 - 1986
- McGill UniversityFellowship, Nephrology, 1977 - 1979
- McGill University Residency, Internal Medicine, 1975 - 1977
- University of Michigan Medical SchoolClass of 1975
Certifications & Licensure
- PA State Medical License 1986 - 2024
- MD State Medical License 1981 - 1993
- American Board of Dermatology Dermatology
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Nephrology
Awards, Honors, & Recognition
- Philadelphia Magazine Castle Connolly, 2004-2014
- America's Top Doctors Castle Connolly, 2004-2014
- America's Top Doctors for Cancer Castle Connolly, 2005-2013
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Clinical Trials
- Interleukin-12 and Interleukin-2 in Treating Patients With Mycosis Fungoides Start of enrollment: 2002 Sep 01
Publications & Presentations
PubMed
- 449 citationsEffects of transforming growth factor beta on the functions of natural killer cells: depressed cytolytic activity and blunting of interferon responsiveness.Alain H. Rook, John H. Kehrl, Lalage M. Wakefield, Anita B. Roberts, Michael B. Sporn
Journal of Immunology. 1986-05-15 - 138 citationsPembrolizumab in Relapsed and Refractory Mycosis Fungoides and Sézary Syndrome: A Multicenter Phase II Study.Michael S. Khodadoust, Alain H. Rook, Pierluigi Porcu, Francine M. Foss, Alison J. Moskowitz
Journal of Clinical Oncology. 2020-01-01 - 93 citationsAntitumor activity of DAB389IL-2 fusion toxin in mycosis fungoidesMansoor N. Saleh, Charles F. LeMaistre, Timothy M. Kuzel, Francine M. Foss, Leonidas C. Platanias
Journal of the American Academy of Dermatology. 1998-07-01
Journal Articles
- Brentuximab Vedotin for Relapsed or Refractory Sézary SyndromePaul L Haun, Sara S Samimi, Alain H Rook, Ellen J Kim, JAMA Dermatology
- Low-Dose Total Skin Electron Beam Therapy as Part of a Multimodality Regimen for Treatment of Sézary SyndromeEllen J Kim, Carmela Vittorio, Paul L Haun, Sara S Samimi, Rachael A Clark, Alain H Rook, JAMA Dermatology
Lectures
- Management Issues in Cutaneous LymphomaAmerican Academy of Dermatology - Annual Meeting 2019 - Washington, D.C. - 3/3/2019
Other
- Clinical presentation, pathologic features, and diagnosis of S??zary syndromeRook AH, Olsen EA
http://www.uptodate.com/contents/clinical-presentation-pathologic-features-and-diagnosis-of-sezary-s
UpToDate, Wolters Kluwer Health - 2013-02-05
Press Mentions
- 'Chromosomal Chaos:' Complex Array of Mutations Found in Rare, Aggressive LeukemiaOctober 7th, 2015
- Triple Therapy Regime Puts Patients with Leukemic Form of Cutaneous Lymphoma in RemissionAugust 19th, 2011
Grant Support
- Toll Receptor Ligand Therapy Of Cutaneous T-Cell LymphomaNational Cancer Institute2008–2011
- Immunotherapy Of Cutaneous T-Cell Lymphoma With Interleukin-12National Cancer Institute2007–2008
- Dendritic Cell Defects In Cutaneous T-Cell LymphomaNational Cancer Institute2003–2007
- Immunotherapy Of Cutaneous T-Cell Lymphoma WNational Cancer Institute2004–2006
- Recombinant Interleukin-12 For Cutaneous T-Cell LymphomaNational Cancer Institute2001–2006
- Recombinant Human IL-12 In Mycosis FungoidesNational Center For Research Resources2004–2005
- Cytokine Therapy Of Cutaneous T Cell LymphomaNational Cancer Institute2000–2004
- Effects Of Interleukin 12 In Cutaneous T Cell LymphomaNational Cancer Institute2001–2002
- Recombinant Interleukin 12 In Patients W/ Stage IA, IB Of IIA MycosisNational Center For Research Resources1999–2002
- Interleukin 12 Therapy Of Cutaneous T Cell LymphomaNational Cancer Institute1999–2000
- Recombinant Human Interleukin 12 In Cutaneous T Cell LymphomaNational Center For Research Resources1997–2000
- Photophoresis With Liquid 8-Methoxsalen In Systemic SclerosisNational Center For Research Resources1996–2000
- Abnormal Cytokine Syntheses In Cutaneous T-Cell LymphomaNational Cancer Institute1993–1995
Professional Memberships
- Fellow
Other Languages
- French
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