AkritSinghSodhiMDPhD

PubMed

• VEGF inhibition increases expression of HIF-regulated angiogenic genes by the RPE limiting the response of wet AMD eyes to aflibercept.
  Deepti Sharma, Evan Lau, Yu Qin, Kathleen Jee, Murilo Rodrigues
  Proceedings of the National Academy of Sciences of the United States of America. 2024-11-12
• Hypoxia-induced BNIP3 facilitates the progression and metastasis of uveal melanoma by driving metabolic reprogramming.
  Jie Sun, Jie Ding, Han Yue, Binbin Xu, Akrit Sodhi
  Autophagy. 2024-09-12
• 1 citations
  The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD.
  Sayan Ghosh, Ruchi Sharma, Sridhar Bammidi, Victoria Koontz, Mihir Nemani
  Nature Communications. 2024-07-21

Journal Articles

• The Role of the Immune Response in Age-Related Macular Degeneration  
  Whitcup, S.M., Sodhi, A., Atkinson, J., Holers, M., Sinha, D., and Dick, A.D., International Journal of Inflammation, 1/1/2013
• Long-term Outcomes in Ranibizumab-Treated Patients With Retinal Vein Occlusion; The Role of Progression of Retinal Nonperfusion  
  Sophie, R., Hafiz, G., Scott, A.W., Zimmer-Galler, I., Nguyen, Q.D., Ying, H., Do, D.V., Solomon, S., Sodhi, A., Gehlbach, P., Duh, E., Baranano, D., and Campochiaro, ..., American Journal of Ophthalmology, 1/1/2013
• Hypoxic Retinal Müller Cells Promote Diabetic Macular Edema by HIF-1-Dependent Upregulation of Angiopoietin-like 4  
  Xin, X., Rodrigues, M., Umapathi, M.D., Kashiwabuchi, F., Ma, T., Wang, S., Hu, J., Bhutto, I., Welsbie, D., Duh, E., Handa, J.T., Eberhart, C.G., Lutty, G., Semenza, ..., Proceedings of the National Academy of Science, USA, 1/1/2013
• Regression of Choroidal Neovascularization in Response to Systemic Chemotherapy for Cancer  
  Hsu, A.W., Sodhi, A., Eberhart, C.G., and Goldberg, M.F., Canadian Journal of Ophthalmology, 1/1/2013
• Scleral Penetration of an Unusually Aggressive Case of a Retinal Hemangioblastoma  
  Rodrigues, M., Iliff, N.T., Eberhart, C.G., Montaner, S., and Sodhi, A., Canadian Journal of Ophthalmology, 1/1/2013
• Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma  
  Ma, T., Jham, B.C., Hu, J., Friedman, E.R., Basile, J.R., Molinolo, A., Sodhi, A., and Montaner, S., Proceedings of the National Academy of Science, USA, 1/1/2010
• Recent Trends in the Management of Rhegmatogenous Retinal Detachment  
  Sodhi, A., Leung, L.S., Do, D.V., West, E.S., Schein, O.D., and Handa, J.T., Survey of Ophthalmology, 1/1/2008
• The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor as a therapeutic target for the treatment of Kaposi's sarcoma  
  Montaner S., Sodhi A., Ramsdell A.K., Martin D., Hu J., Sawai E.T., and Gutkind J.S., Cancer Research, 1/1/2006
• The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's Sarcoma Associated Herpesvirus G Protein-Coupled Receptor  
  Sodhi, A., Chaisuparat, R., Hu, J., Ramsdell, R.K., Manning, R.D., Sausville, E.A, Sawai, E.T., Molinolo, A.A., Gutkind, J.S., and Montaner, S., Cancer Cell, 1/1/2006
• Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck  
  Amornphimoltham P., Patel V., Sodhi A., Nikitakis N.G., Sauk J.J., Sausville E.A., Molinolo A.A., and Gutkind J.S., Cancer Research, 1/1/2005
• Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor  
  Sodhi, A., Montaner, S., Roman, J., Li, Y., Sawai, E.T., and Gutkind, J.S., Proceedings of the National Academy of Science, USA, 1/1/2004
• Viral hijacking of G-protein-coupled-receptor signalling networks  
  Sodhi, A., S. Montaner, and Gutkind, J.S., Nature Reviews Molecular and Cellular Biology, 1/1/2004
• Does Dysregulation of a Deregulated Viral GPCR Trigger Kaposi's Sarcomagenesis?  
  Sodhi, A., S. Montaner, and Gutkind, J.S., The FASEB Journal, 1/1/2004
• Rac1 function is required for Src-induced transformation: Evidence of a role for Tiam1 and Vav2 in Rac activation by Src  
  Servitja, J.M., Marinissen, M.J., Sodhi, A., Bustelo, X.R., and Gutkind, J.S., The Journal of Biological Chemistry, 1/1/2003
• The Kaposi's Sarcoma Associated Herpesvirus G Protein-Coupled Receptor Induces Endothelial Cell Survival through the Activation of Akt/PKB  
  Montaner, S., Sodhi, A., Pece, S., Mesri, E., and Gutkind, J.S., Cancer Research, 1/1/2001
• The Kaposi's Sarcoma Associated Herpesvirus G Protein-Coupled Receptor Upregulates VEGF Expression and Secretion through Multiple Signaling Pathways Acting on Hypoxia ...  
  Sodhi, A., Montaner, S., Patel, V., Zohar, M., Bais, C., Mesri, E., and Gutkind, J.S., Cancer Research, 1/1/2000
• MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1 alpha in rasV12 stimulation of VEGF  
  Sodhi, A., Montaner, S., Miyazaki, H., and Gutkind, J.S., Biochemical and Biophysical Research Communications, 1/1/2000
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Books/Book Chapters

• Retina 
  Chapter: Molecular Genetics of Choroidal Melanoma and its relevance to Clinical Practice. 
  Sodhi, A. and Merbs, S.Editors: Ryan, S.J..Elesvier/Mosby, Philadelphia, PA2012
• Signal Transduction and Human Disease 
  Chapter: Molecular mechanisms of cancer. 
  Page 71 - 142Sodhi A., Montaner S, and Gutkind, J.S.Editors: Finkel T, Gutkind J.S..John Wiley & Sons, Hoboken, NJ2003

Lectures

• "Retina Emergencies." 
  Wilmer Eye Institute, Johns Hopkins School of Medicine, 2012, 2013 - 1/1/2014
• "Surgical Management of Proliferative Diabetic Retinopathy." (Panel member). 
  Johns Hopkins School of Medicine, Baltimore, MD - 10/11/2013
• "Identification of New Therapeutic Targets for the Treatment of Diabetic Eye Disease?" 
  Johns Hopkins School of Medicine, Baltimore, MD - 6/14/2013
• "Identification of Novel Therapeutic Targets for the Treatment of Diabetic Eye Disease." 
  Wilmer Eye Institute, Baltimore, MD - 5/14/2013
• "The Immune System in Age Related Macular Degeneration." 
  Irvine, CA - 1/26/2013
• "Imaging in Retinal Disease. What's a Retina Specialist to do?" 
  Johns Hopkins School of Medicine, Baltimore, MD - 1/19/2013
• "Vein Occlusion Case Presentations." (Panel member) 
  Johns Hopkins School of Medicine, Baltimore, MD - 10/12/2012
• "Case Presentations. Age-Related Macular Degeneration in 2012: The Paradigm Continues to Evolve." 
  Johns Hopkins School of Medicine, Baltimore, MD - 6/9/2012
• "Case Presentations." 
  Johns Hopkins School of Medicine, Baltimore, MD - 11/11/2011
• "HIF-The Good, The Bad, and The Ugly." 
  Wilmer Eye Institute, Baltimore, MD - 5/17/2011
• "Retinal Detachment and Proliferative Vitreoretinopathy" 
  Wilmer Eye Institute, Johns Hopkins School of Medicine, 2010 - 1/1/2011
• "Pseudophakic Cystoid Macular Edema." 
  Wilmer Eye Institute, Johns Hopkins School of Medicine, 2010 - 1/1/2011
• "Choosing a Career as a Physician-Scientist." 
  Johns Hopkins School of Medicine - 12/13/2010
• "Management of Capillary Non-Perfusion and Neovascularization Following Retina Vein Occlusion." 
  Johns Hopkins School of Medicine, Baltimore, MD - 12/11/2010
• "Uveal Melanoma: Current Therapies and Emerging Targets." 
  Johns Hopkins School of Medicine, Baltimore, MD - 12/3/2010
• "Retinal Anatomy and Physiology, Including Photochemistry" 
  Johns Hopkins School of Medicine, Baltimore, MD - 3/27/2010
• "Hypoxic Dysregulation in Retinal Neovascular Disease." 
  Kellogg Eye Institute, University of Michigan, Ann Arbor, MI - 10/19/2009
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