AdrianVellaMD

PubMed

• Enhanced quantification of α-cell suppression by hyperglycemia using a high-sensitivity glucagon assay.
  Roy B Dyer, Marcello C Laurenti, Hannah E Christie, Sneha Mohan, Aoife Egan
  American Journal of Physiology. Endocrinology and Metabolism. 2024-12-09
• The Longitudinal Effect of Diabetes-Associated Variation in TCF7L2 on Islet Function in Humans.
  Maya Zeini, Marcello C Laurenti, Aoife M Egan, Kalpana Muthusamy, Anisha Ramar
  Diabetes. 2024-09-01
• 1 citations
  An unclear role for the GLP-1 metabolite GLP-1(9-36) in human islet physiology.
  Aleksey Matveyenko, Adrian Vella
  Diabetologia. 2024-07-01

Journal Articles

• Hypoglycemia After Gastric Bypass Surgery: Current Concepts and Controversies  
  Tracey McLaughlin, Adrian Vella, The Journal of Clinical Endocrinology and Metabolism
• The Oral Minimal Model Method  
  Cobelli C, Dalla Man C, Toffolo G, Basu R, Vella A, Rizza R, Diabetes, 4/1/2014
• Beta-Cell Function After Weight-Loss Induced by Bariatric Surgery  
  Vella A., Physiology (Bethesda), 3/1/2014
• Screening for gestational diabetes: a systematic review and meta-analysis  
  Prutsky GJ, Domecq JP, Sundaresh V, Elraiyah T, Nabhan M, Prokop LJ, Vella A, Montori VM, Murad MH, J Clin Endocrinol Metab, 11/1/2013
• Glucose targets in pregnant women with diabetes: a systematic review and meta-analysis  
  Prutsky GJ, Domecq JP, Wang Z, Carranza Leon BG, Elraiyah T, Nabhan M, Sundaresh V, Vella A, Montori VM, Murad MH, J Clin Endocrinol Metab, 11/1/2013
• The Contribution of Endogenous Glucagon-Like Peptide-1 to Glucose Metabolism after Roux-en-Y Gastric Bypass  
  Shah M, Law JH, Micheletto F, Sathananthan M, Man CD, Cobelli C, Rizza RA, Camilleri M, Zinsmeister AR, Vella A, Diabetes, 10/2/2013
• Clinical vs Neurophysiology Trial 3 Investigators A trial of proficiency of nerve conduction: greater standardization still needed  
  Dyck PJ, Albers JW, Wolfe J, Bolton CF, Walsh N, Klein CJ, Zafft AJ, Russell JW, Thomas K, Davies JL, Carter RE, Melton LJ 3rd, Litchy WJ, Muscle Nerve, 9/1/2013
• The Ghrelin Agonist RM-131 Accelerates Gastric Emptying of Solids and Reduces Symptoms in Patients with Type 1 Diabetes Mellitus  
  Shin A, Camilleri M, Busciglio I, Burton D, Smith SA, Vella A, Ryks M, Rhoten D, Zinsmeister AR, Clin Gastroenterol Hepatol, 4/29/2013
• Direct Effects of Exendin-(9,39) and GLP-1-(9,36)amide on Insulin Action, Beta-Cell Function and Glucose Metabolism in Non-Diabetic Subjects  
  Sathananthan M, Farrugia LP, Miles JM, Piccinini F, Man CD, Zinsmeister AR, Cobelli C, Rizza RA, Vella A, Diabetes, 4/1/2013
• 69-year-old man with recurrent episodes of confusion and diaphoresis  
  Donegan DM, Vella A, Mayo Clin Proc, 4/1/2013
• Mechanism of action of DPP-4 inhibitors-new insights  
  Vella A, JCEM, 1/1/2013
• "Unequivocally Abnormal" vs "Usual" Signs and Symptoms for Proficient Diagnosis of Diabetic Polyneuropathy: Cl vs N Phys Trial  
  Dyck PJ, Overland CJ, Low PA, Litchy WJ, Davies JL, Dyck PJ, Carter RE, Melton LJ, Andersen H, Albers JW, Bolton CF, England JD, Klein CJ, Llewelyn G, Mauermann ML, Ru..., Arch Neurol, 9/1/2012
• Predicting Diabetes Using Measures of Beta-Cell Function  
  Vella A, Zinsmeister AR, Diabetes, 1/1/2012
• Late-night salivary cortisol for diagnosis of Cushing's syndrome by liquid chromatography/tandem mass spectrometry assay  
  Erickson D, Singh RJ, Sathananthan A, Vella A, Bryant SC, Clin Endocrinol (Oxf), 1/1/2012
• Diabetes-associated common genetic variation and its association with GLP-1 concentrations and response to exogenous GLP-1  
  Smushkin G, Sathananthan M, Sathananthan A, Dalla Man C, Micheletto F, Zinsmeister AR, Cobelli C, Vella A, Diabetes, 1/1/2012
• Defects in GLP-1 Response to an Oral Challenge Do Not Play a Significant Role in the Pathogenesis of Prediabetes  
  Smushkin G, Sathananthan A, Dalla Man C, Zinsmeister AR, Camilleri M, Cobelli C, Rizza RA, Vella A, J Clin Endocrinol Metab, 1/1/2012
• US-guided ethanol ablation of insulinomas: a new treatment option  
  Levy MJ, Thompson GB, Topazian MD, Callstrom MR, Grant CS, Vella A, Gastrointest Endosc, 1/1/2012
• A Concerted Decline in Insulin Secretion and Action occurs across the Spectrum of Fasting and Post-Challenge Glucose Concentrations  
  Sathananthan A, Dalla Man C, Zinsmeister AR, Camilleri M, Rodeheffer RJ, Toffolo G, Rizza RA, Cobelli C, Vella A, Clin Endocrinol (Oxf), 1/1/2012
• Association of TCF7L2 Allelic Variations with Gastric Function, Satiation, and GLP-1 Levels  
  Vazquez-Roque MI, Camilleri M, Vella A, Carlson P, Laugen J, Zinsmeister AR, Clin Transl Sci, 6/1/2011
• Carbohydrate Metabolism and the Skeleton: Picking a Bone with the Beta-Cell  
  Kumar R, Vella A, JCEM, 5/1/2011
• Association of genetic variation in cannabinoid mechanisms and gastric motor functions and satiation in overweight and obesity  
  Vazquez-Roque MI, Camilleri M, Vella A, Carlson P, Laugen J, Zinsmeister AR, Neurogastroenterol Motil, 4/7/2011
• Setting the bar for laparoscopic resection of sporadic insulinoma  
  Richards ML, Thompson GB, Farley DR, Kendrick ML, Service FJ, Vella A, Grant CG, World J Surg, 4/1/2011
• Outcomes and quality of life after partial pancreatectomy for noninsulinoma pancreatogenous hypoglycemia from diffuse islet cell disease  
  Vanderveen KA, Grant CS, Thompson GB, Farley DR, Richards ML, Vella A, Vollrath B, Service FJ, Surgery, 12/1/2010
• Effect of phylloquinone supplementation on glucose homeostasis in humans  
  Kumar R, Binkley N, Vella A, Am J Clin Nutr., 12/1/2010
• What is Type 2 Diabetes?  
  Smushkin G, Vella A, Medicine (Baltimore), 11/1/2010
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Books/Book Chapters

• Companion to Peripheral Neuropathy: Illustrated Cases And New Developments 
  Chapter: Evaluation of diabetic polyneuropathy: design of the neurologic examination versus clinical neurophysiology tests trial. 
  Page 321 - 326Dyck PJ, Overland CJ, Low PA, Litchy WJ, Davies JL, Dyck PJB, O'Brien PC, Albers JW, Andersen H, Bolton CF, England JD, Klein CJ, Llewelyn JG, Mauermann ML, Russell JW...Editors: Dyck PJ; et al.Saunders/Elsevier, Philadelphia2010
• Companion to Peripheral Neuropathy: Illustrated Cases And New Developments 
  Chapter: Testing of touch-pressure sensation: introduction of the touch-pressure sensogram. 
  Page 327 - 329Dyck PJ, Winkler JA, Andrews KL, Kavros SJ, Vella A, Davies JLEditors: Dyck PJ; et al.Saunders/Elsevier, Philadelphia2010
• Pharmacology And Therapeutics: Principles To Practice 
  Chapter: Diabetes mellitus. 
  Page 557 - 570Rizza RA, Vella AEditors: Waldman SA, Terzic A.Saunders/Elsevier, Philadelphia2009
• Endocrine Surgery 
  Chapter: Surgical management of hypoglycemic disorders. 
  Vella A, Service FJ, Thompson GBWiley2009
• Type 2 Diabetes: Principles and Practice 
  Chapter: Gastrointestinal and autonomic complications of diabetes mellitus. 
  Page 327 - 340Vella A, Camilleri MEditors: Goldstein BJ, Muller-Wieland D.Informa Healthcare, New York, NY2008
• Diabetes Mellitus 
  Chapter: Endocrinologic Therapeutic. 
  Vella A, Rizza REditors: Waldman SA, Terzig A.2008
• Clinical Endocrine Oncology 
  Chapter: Insulinomas and hypoglycemia. 
  Page 455 - 461Vella A, Service FJEditors: Hay ID, Wass JAH.Blackwell Pub., MaldenEdition 2nd,2008
• Type 2 Diabetes Mellitus: An Evidence-based Approach To Practical Management 
  Chapter: Detection and diagnosis of Type 2 Diabetes. 
  Page 75 - 83Vella AEditors: Feinglos MN, Bethel MA.Humana Press, Totowa2008
• Mayo Clinic Internal Medicine Board Review, 2004-2005 
  Chapter: Endocrinology. 
  Page 197 - 252Vella A, Natt NEditors: Habermann TM.Lippincott Williams & Wilkins, Philadelphia2004
• Textbook of Type 2 Diabetes 
  Chapter: Gastrointestinal and autonomic complications of diabetes mellitus. 
  Page 275 - 288Vella A, Camilleri MEditors: Goldstein BJ, Muller-Wieland D.Martin Dunitz, London2003
• Textbook of Diabetes 
  Chapter: Metabolic disturbances in diabetes mellitus. 
  Page 1 - 14Vella A, Rizza RAEditors: Pickup JC, Williams G.Blackwell Science, MaldenEdition 3rd,2003
• Type 1 Diabetes: Etiology and Treatment 
  Chapter: Surgery for the patient with type 1 diabetes. 
  Page 361 - 371Vella A, Rizza RAEditors: Sperling, MA.Humana Press, Totowa2003
• Mayo Clinic Internal Medicine Board Review, 2002-2003 
  Chapter: Endocrinology. 
  Page 223 - 288Vella A, Natt NEditors: Habermann TM.Lippincott Williams & Wilkins, PhiladelphiaEdition 5th,2002
• Current Issues In Rheumatology and Dermatology 
  Chapter: 74-year-old woman with proptosis: proptosis in Wegener's granulomatosis. 
  Page 529 - 533Vella A, McPhail I, Litin SEditors: C. Mallia & I Uitto.Plenum Publishing Company, New York, NY1999
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Abstracts/Posters

• Diabetes-associated genetic variation and GLP-1 secretion and action GLP-1 in non-diabetic subjects.
  Smushkin G, Dalla Man C, Micheletto F, Sathananthan A, Camilleri M, Cobelli C, Rizza RA, Vella A, Diabetes and Prediabetes, Madrid, 4/1/2011
• Minimal Model indices and genetic biomarkers in the pathogenesis of diabetes.
  Sambo F, Di Camillo B, Toffolo G, Dalla Man C, Cobelli C, Vella A, Diabetes and Prediabetes, Madrid, 4/1/2011
• The interaction of colesevelam with sitagliptin suggests differential effects on fasting and postprandial glucose metabolism in subjects with type 2 diabetes.
  Smushkin G, Dalla Man C, Sathananthan M, Cobelli C, Vella A, EASD, 1/1/2011
• The effect of Colesevelam Hydrochloride on fasting and postprandial glucose metabolism in subjects with type 2 diabetes.
  Smushkin G, Dalla Man C, Sathananthan M, Cobelli C, Vella A, Diabetes, 1/1/2011
• The effect of TCF7L2 genotype on postprandial glucose metabolism in elderly, non-diabetic subjects.
  Sathananthan M, Dalla Man C, Toffolo G, Cobelli C, Nair KS, Rizza RA, Vella A, Diabetes, 1/1/2011
• Estimation of GLP-1 induced potentiation of insulin secretion from an oral model.
  Micheletto F, Dalla Man C, Vella A, Cobelli C, Diabetes, 1/1/2011
• Incorporation of Biochemical, Anatomic and Perfusion Data to Improve the Localization of Occult, Sporadic Insulinoma by Selective Intra-arterial Calcium Stimulation wi...
  Thompson SM, Andrews JC, Thompson GB, Grant CS, Lloyd RV, Service FJ, Vella A, Endocrine Society-Annual Meeting, 6/1/2010
• A pilot study examining the effect of GLP1R polymorphisms on insulin secretion in response to glucose and GLP-1 infusion in non-diabetic subjects.
  Vella A, Sathananthan A, Micheletto F, Dalla Man C, Toffolo G, Cobelli C, Zinsmeister AR, Camilleri M, Rizza RA, Diabetologia, 9/1/2009
• Sitagliptin effects on triglyceride and free fatty acid metabolism.
  Nelson RH, Miles JM, Vella A, Diabetologia, 9/1/2009
• A Model of GLP-1 Action on Insulin Secretion in Nondiabetic Subjects.
  Dalla Man C, Micheletto F, Sathananthan A, Camilleri M, Rizza RA, Vella A, Cobelli, Diabetes, 1/1/2009
• The relationship of active and total GLP-1 concentrations to insulin secretion and action across a range of glucose tolerance in non-diabetic subjects.
  Smushkin G, Man CD, Sathananthan A, Giesler PD, Camilleri M, Toffolo G, Cobelli C, Rizza RA, Vella A, Diabetes, 1/1/2009
• Sitagliptin effects on triglyceride and free fatty acid metabolism.
  Nelson RH, Miles JM, Vella A, J Investig Med, 1/1/2009
• The effect of delayed incretin clearance on fasting and postprandial glucose turnover in subjects with impaired fasting glucose.
  Vella A, Dalla Man C, Bock G, Basu R, Giesler PD, Laugen JM, Toffo G, Cobelli C, Rizza RA, Diabetologia, 9/1/2008
• Association of traditional risk factors and genetic polymorphisms with new onset diabetes mellitus (NODM) in kidney transplant recipients.
  Chakkera H, Raza S, Wolford J, Vella A, Hanson R, Weil J, Heilman R, Mulligan D, Mazur M, Reddy S, Moss A, Mekeel K, Cerhan J, Am J Transplant, 5/1/2008
• The contribution of type 2 diabetes-associated common genetic variation to cognitive impairment: evidence for common predisposition to diabetes and dementia?
  Vella A, Roberts RO, Pankratz VS, Knopman DS, Petersen RC, ADA, 1/1/2008
• Secular trends in the presentation and management of functioning insulinoma at the Mayo Clinic: 1987-2007.
  Placzkowski K, Vella A, Thompson GB, Grant CS, Service FJ, Endo, 1/1/2008
• Treatment of diabetes and outcome after myocardial infarction: A community study.
  Patch RK, Arruda-Olson AM, Leibson CL, Vella A, Weston SA, Killian JM, Frye RL, Roger VL, Circulation, 10/1/2007
• The effect of the dipeptidyl peptidase 4 inhibitor vildagliptin, on satiation and glucose metabolism in type 2 diabetes.
  Vella A, Bock G, Giesler PD, Burton DB, Rizza RA, Camilleri M, ADA Annual Meeting, 6/1/2007
• Effect of a dipeptidyl peptidase 4 (DPP-4) inhibitor, vildagliptin, on gastrointestinal function, nutrient intake and glucose metabolism in type 2 diabetes.
  Vella A, Bock G, Giesler PD, Burton DB, Foley JE, Rizza RA, Camilleri M, Neurogastroenterol Motil, 5/1/2007
• Postprandial hypoglycemia after upper gastrointestinal bypass surgery.
  Vella A, Thompson GB, Grant CS, Andrews JC, Lloyd RV, Service FJ, Endo, 1/1/2007
• The effect of the dipeptidyl peptidase IV inhibitor LAF237 on gastrointestinal function and glucose metabolism in type 2 diabetes.
  Vella A, Bock G, Giesler PD, Burton DB, Rizza RA, Camilleri M, EASD Annual Meeting, Copenhagen, 9/1/2006
• Construction of a dense tag SNP map to examine the effect of IGF1 on predisposition to type 1 diabetes.
  Vella A, Cooper JD, Godfrey L, Lowe CE, Walker N, Todd JA, Endo, 1/1/2006
• Association analysis of the immune response gene FYN in type 1 diabetes.
  Vella A, Cooper JD, Godfrey L, Lowe CE, Walker N, Todd JA, Endo, 1/1/2005
• The Arg620Trp polymorphism in PTPN22 locus is associated with type 1 diabetes.
  Vella A, Smyth D, cooper JD, Tuomilehto-Wolf E, Tuomilehto J, Undlien DE, Ronningen KS, Guja C, Ionescu-Tirgoviste C, Savage DA, Dunger DB, Strachan DP, Ring SM, Todd JA, EASD Annual Meeting, Munich, 9/1/2004
• Convincing statistical support for association of the Arg620Trp polymorphism in PTPN22 locus with Type I diabetes.
  Vella A, Smyth D, Cooper JD, Tuomilehto-Wolf E, Tuomilehto J, Undlien DE, Ronningen KS, Guja C, Ionescu-Tirgoviste C, Savage DA, Dungar DB, Trachen DP, Ring SM, Todd JA, Diabetologia, 8/1/2004
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Lectures

• Clinical Aspects of Glycemic Control: From Hypoglycemia to Novel Therapeutic Pathways 
  ENDO 2019 - New Orleans, LA - 3/25/2019
• Effects of Metformin on Bile Acid Metabolism in Type 2 Diabetes 
  Rochester, MN - 6/15/2014