AdrianSandraDobsMD

Diabetes, Gonad Disorders & Reproductive, Lipid Metabolism

Professor of Medicine, Professor of Oncology, Johns Hopkins University School of Medicine; Director, Johns Hopkins Clinical Reserch Network, Former Director, Johns Hopkins - SYSU (China) Collaboration, Director - Johns Hopkins Center to Reduce Cancer Disparities

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Office
601 North Caroline Street
Baltimore, MD 21287
Phone+1 410-955-9270

Fax+1 410-367-2042

Summary

Adrian Sandra Dobs, MD, MHS, is Professor of Medicine and Oncology and Director of the Johns Hopkins Clinical Research Network of the Johns Hopkins Institute for Clinical and Translational Research (JHCRN). Dr Dobs is also Director of the Johns Hopkins Center for the Reduction of Cancer Disparities of the Johns Hopkins Comprehensive Cancer. The JHCRN is a multi-institutional collaboration linking academic and community hospitals in the mid-Atlantic United States.

Dr Dobs received her undergraduate degree from Cornell University, a medical degree from Albany Medical College, in New York, and completed an internship in internal medicine at Montefiore Hospital, Albert Einstein College of Medicine, in the Bronx, New York. She held a fellowship in endocrinology from Johns Hopkins University School of Medicine and earned a master in health sciences degree in cardiovascular epidemiology at the Johns Hopkins University Bloomberg School of Public Health.

Dr Dobs is an investigator on several NIH-funded studies evaluating the relationship of sex hormones and cardiovascular risk. She lectures in the United States and internationally in these areas, as well as aging and testosterone therapy and testosterone and cardiovascular disease.

With book chapters, monographs, and journal articles, as well as television and Web contributions, Dr Dobs has published extensively on topics that include sex hormones and its relationship to metabolic disorders. Journals publishing her research include the New England Journal of Medicine, Journal of Clinical Endocrinology and Metabolism, JAIDS, and Journal of Andrology. She co-chairs the International Registry for Hypogonadal Men.

Dr Dobs is very active in mentoring medical students and postdoctoral fellows and was honored by the Johns Hopkins University School of Medicine with the David M. Levine Excellence in Mentoring Award.

Education & Training

Johns Hopkins UniversityM.H.S., Cardiovascular Epidemiology, 1990
Johns Hopkins UniversityFellowship, Endocrinology, Diabetes, and Metabolism, 1982 - 1984
Montefiore Medical Center/Albert Einstein College of Medicine (Moses and Weiler Campuses)Residency, Internal Medicine, 1978 - 1980
Albany Medical CollegeClass of 1978
Cornell UniversityB.S., Nutrition Sciences, 1973

Certifications & Licensure

FL State Medical License 2022 - Present
MD State Medical License 1982 - 2026
NC State Medical License 2020 - 2022
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2002-2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013-2014
Top Doctors:Baltimore Area Castle Connolly, 2012
Top Doctors:Washington-Baltimore Castle Connolly, 2012
David M. Levine Excellence in Mentoring Award Johns Hopkins University School Medicine, 2009
Research Award for Women Physicians Stetler Foundation, 1986
Paul Ehrlich Young Investigator Award, Certificate of Merit Johns Hopkins University School Medicine, 1984
Carnegie Mellon Fellow Johns Hopkins University School Medicine, 1984
Davidoff Award for Clinical Teaching Montefiore Medical Center, 1982
Clinical Electives for Medical Students; Endocrinology & Metabolism National Institutes of Health, 1977
Special Fellowship Program for Medical Students, Diabetes Center Vanderbilt University, 1976
Research Fellowship, Summer Albany Medical College, 1975
Scholarship Leopold Schepp Foundation, 1975
Super Doctor SuperDoctors.com
Whos Who in Medicine and Healthcare Marquis Whos Who
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Clinical Trials

A Fish Oil Supplement to Maintain Body Weight in Patients With Disease-Related Weight Loss Start of enrollment: 2004 Jun 01
Completed
Phase 2
Effects of Endocrine Health on Mental Performance of Men and Women Using Drugs Start of enrollment: 2004 Aug 01
Completed
Omega-3 Fatty Acids for High Triglycerides in HIV-infected Patients Start of enrollment: 2006 Oct 01
Completed
Phase 4
Acupuncture for Mucositis Pain in Cancer Care Start of enrollment: 2007 Aug 01
Withdrawn
Not Applicable
American Ginseng to Improve HIV-Associated Fatigue: A Randomized, Placebo-Controlled, Parallel Design, Multiple-Dose Clinical Trial Start of enrollment: 2013 Feb 01
Completed
Phase 2
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Publications & Presentations

PubMed

201 citations
Cumulative exposure to nucleoside analogue reverse transcriptase inhibitors is associated with insulin resistance markers in the Multicenter AIDS Cohort Study
Todd T. Brown, Xiuhong Li, Stephen R. Cole, Lawrence A. Kingsley, Frank J. Palella
AIDS. 2005-09-02
626 citations
Antiretroviral therapy and the prevalence and incidence of diabetes mellitus in the multicenter AIDS cohort study.
Todd T. Brown, Stephen R. Cole, Xiuhong Li, Lawrence A. Kingsley, Frank J. Palella
Archives of Internal Medicine. 2005-05-23
7 citations
Age-Specific Serum Total and Free Estradiol Concentrations in Healthy Men in US Nationally Representative Samples.
Susan Chadid, John R. Barber, Sabine Rohrmann, William G. Nelson, James D. Yager
Journal of the Endocrine Society. 2019-07-19

Journal Articles

To T or Not to T: Differences in Testosterone Use and Discontinuation by HIV Serostatus Among Men Who Have Sex with Men*
T T Brown, J E Lake, W S Post, A Dobs, HIV Medicine
Lipoprotein particle profile by nuclear magnetic resonance spectroscopy in adolescents and young women with PCOS provides insights into their cardiovascular and metabo...
Dobs A, Remaley A, Stratakis AC, JCEM, 1/1/2015
Increases in duration of first highly active antiretroviral therapy over time (1996-2009) and associated factors in the Multicenter AIDS Cohort Study
Slama L, Li X, Brown T, Jacobson LP, Pialoux G, Macatangay B, Bolan RK, Phair J, Palella FJ Jr; Multicenter AIDS cohort Study (Dobs, AS), J Acquir Immune Defic Syndr, 1/1/2014
Alogliptin after acute coronary syndrome in patients with type 2 diabetes
White WB, Cannon CP, Heller SR, Nissen SE, Bergenstal RM, Bakris GL, Perez AT, Fleck PR, Mehta CR, Kupfer S, Wilson C, Cushman WC, Zannad F; EXAMINE Investigators (Dob..., N Engl J Med, 1/1/2013
Contribution of genetic background, traditional risk factors, and HIV-related factors to coronary artery disease events in HIV-positive persons
Rotger M, Glass TR, Junier T, Lundgren J, Neaton JD, Poloni ES, van 't Wout AB, Lubomirov R, Colombo S, Martinez R, Rauch A, Günthard HF, Neuhaus J, Wentworth D, van M..., Clin Infect Dis, 1/1/2013
A Novel Testosterone 2% Gel for the Treatment of Hypogonadal Males
Dobs AS, McGettigan J, Norwood P, Howell J, Waldie E, Chen Y, J Androl, 1/1/2012
Factors affecting brain structure in men with HIV disease in the post-HAART era
Becker JT, Maruca V, Kingsley LA, Sanders JM, Alger JR, Barker PB, Goodkin K, Martin E, Miller EN, Ragin A, Sacktor N, Selnes O; Multicenter AIDS Cohort Study (Dobs AS), Neuroradiology, 1/1/2012
Decreased limb muscle and increased central adiposity are associated with 5-year all-cause mortality in HIV infection
Scherzer R, Heymsfield SB, Lee D, Powderly WG, Tien PC, Bacchetti P, Shlipak MG, Grunfeld C; Study of Fat Redistribution and Metabolic Change in HIV Infection (FRAM) (..., AIDS, 1/1/2011
Subcortical brain atrophy persists even in HAART-regulated HIV disease
Becker JT, Sanders J, Madsen SK, Ragin A, Kingsley L, Maruca V, Cohen B, Goodkin K, Martin E, Miller EN, Sacktor N, Alger JR, Barker PB, Saharan P, Carmichael OT, Thom..., Brain Imaging Behav, 1/1/2011
Longitudinal psychomotor speed performance in human immunodeficiency virus-seropositive individuals: impact of age and serostatus
Sacktor N, Skolasky RL, Cox C, Selnes O, Becker JT, Cohen B, Martin E, Miller EN; Multicenter AIDS Cohort Study (MACS) (Dobs AS), J Neurovirol, 1/1/2010
Regional adipose tissue measured by MRI over 5 years in HIV-infected and control participants indicates persistence of HIV-associated lipoatrophy
Grunfeld C, Saag M, Cofrancesco J Jr, Lewis CE, Kronmal R, Heymsfield S, Tien PC, Bacchetti P, Shlipak M, Scherzer R, Study of Fat Redistribution and Metabolic Change ..., AIDS, 1/1/2010
LH and non-SHBG testosterone and estradiol levels during testosterone replacement of hypogonadal men: further evidence that steroid negative feedback increases as men ...
Winters SJ, Wang C, Fortigel Study Group (Dobs AS), J Androl, 1/1/2010
HIV-Selectest enzyme immunoassay and rapid test: ability to detect seroconversion following HIV-1 infection
Khurana S, Norris PJ, Busch MP, Haynes BF, Park S, Sasono P, Mlisana K, Salim AK, Hecht FM, Mulenga J, Chomba E, Hunter E, Allen S, Nemo G, Rodriguez-Chavez IR, Women'..., J Clin Microbiol, 1/1/2010
Vascular risk factors, HIV serostatus, and cognitive dysfunction in gay and bisexual men
Becker JT, Kingsley L, Mullen J, Cohen B, Martin E, Miller EN, Ragin A, Sacktor N, Selnes OA, Visscher BR, Multicenter AIDS Cohort Study (Dobs AS), Neurology, 1/1/2009
Effect of tuberculosis on the survival of HIV-infected men in a country with low tuberculosis incidence
Lopez-Gatell H, Cole SR, Margolick JB, Witt MD, Martinson J, Phair JP, Jacobson LP, Multicenter AIDS Cohort Study (Dobs AS), AIDS, 1/1/2008
Simple anthropometric measures correlate with metabolic risk indicators as strongly as magnetic resonance imaging-measured adipose tissue depots in both HIV-infected a...
Scherzer R, Shen W, Bacchetti P, Kotler D, Lewis CE, Shlipak MG, Heymsfield SB, Grunfeld C, Study of Fat Redistribution Metabolic Change in HIV Infection (FRAM) (Dobs AS), Am J Clin Nutr, 1/1/2008
The associations of regional adipose tissue with lipid and lipoprotein levels in HIV-infected men
Wohl D, Scherzer R, Heymsfield S, Simberkoff M, Sidney S, Bacchetti P, Grunfeld C, FRAM Study Investigators (Dobs AS), J Acquir Immune Defic Syndr, 1/1/2008
CME Program on Testosterone Replacement Therapy
Dobs A, Federal Practitioner, 1/1/2008
Regional adipose tissue and elevations in serum aminotransferases in HIV-infected individuals
Tien PC, Kotler DP, Overton ET, Lewis CE, Rimland D, Bacchetti P, Scherzer R, Gripshover B, Study of Fat Redistribution and Metabolic Change in HIV Infection Investiga..., J Acquir Immune Defic Syndr, 1/1/2008
Fat Redistribution and Metabolic Changes in HIV Infection Study Investigators (Dobs AS): Regional adipose tissue and lipid and lipoprotein levels in HIV-infected women
Currier J, Scherzer R, Bacchetti P, Heymsfield S, Lee D, Sidney S, Tien PC, J Acquir Immune Defic Syndr, 1/1/2008
Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia
Ataga KI, Smith WR, De Castro LM, Swerdlow P, Saunthararajah Y, Castro O, Vichinsky E, Kutlar A, Orringer EP, Rigdon GC, Stocker JW, ICA-17043-05 Investigators (Dobs AS), Blood, 1/1/2008
Prospective study of attitudinal and relationship predictors of sexual risk in the multicenter AIDS cohort study
Ostrow DG, Silverberg MJ, Cook RL, Chmiel JS, Johnson L, Li X, Jacobson LP, Multicenter AIDS Cohort Study (Dobs AS), AIDS Behav, 1/1/2008
Comparison of dual-energy X-ray absorptiometry and magnetic resonance imaging-measured adipose tissue depots in HIV-infected and control subjects
Scherzer R, Shen W, Bacchetti P, Kotler D, Lewis CE, Shlipak MG, Punyanitya M, Heymsfield SB, Grunfeld C, Study of Fat Redistribution Metabolic Change in HIV Infection..., Am J Clin Nutr, 1/1/2008
High prevalence of alcohol use among hepatitis C virus antibody positive injection drug users in three US cities
Campbell JV, Hagan H, Latka MH, Garfein RS, Golub ET, Coady MH, Thomas DL, Strathdee SA; The STRIVE Project (Dobs AS), Drug Alcohol Depend, 1/1/2006
Testosterone Deficiency and Supplementation in Chronic Disease States
Dobs A, Med Clin North Am, 1/1/2006
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Books/Book Chapters

Endocrine Clinics.
Chapter: Androgen effects on lipids.
Monroe A, Dobs ASEditors: Annabelle Rodriguex.2012
Modern Nutrition in Health and Disease
Chapter: Nutritional Management of Diabetes.
Dobs ASEditors: Ross AC, Caballero B, Cousins RJ, Tucker KL, Ziegler TR.Lippincott Williams & Wilkins, Baltimore, MDEdition 11th,2012
Medical Care of Cancer Patients.
Chapter: Hypogonadism and Hormone Replacement Therapy in Men with Cancers.
Lee C, Basaria S, Dobs ASEditors: Yeung S-C J, Escalante CP, Gagel RF.BC Decker, Shelton, CT2009
Proceedings from the TU 1st Annual Conference on Improving Clinical Outcomes in Hypogonadism, Los Angeles
Chapter: Hypogonadism Treatment Considerations, Monitoring and Follow Up.
Dobs A2008
Wild-Type Food in Health Promotion and Disease Prevention. The Columbus Concept.
Chapter: Evaluating the Biological Activity and Effects on Human Health and Fish Oils and its Omega-3 Fatty Acids.
Page 195 - 214Edlestein D, Dobs ASEditors: De Meester F, Watson RR.Humana Press Inc, Totowa, NJ2008
Integrative Oncology: Incorporating Complementary Medicine into Conventional Cancer Care.
Chapter: Acupuncture for the Side Effects of Cancer Treatments.
Lee S, Menten K, Dobs AHumana Press Inc, Totowa, NJ2008
Alternative/Complementary/Integrative Medicine Cancer Medicine: Interactions with Conventional Medicine and Medical Institutions.
Chapter: The Johns Hopkins Complementary and Integrative Medicine Service.
Menten K, Lee S, Dobs ASEditors: Cohen L.Humana Press Inc, Totowa, NJ2008
AAHIVM Fundamentals of HIV Medicine for the HIV Specialist.
Chapter: Endocrine Disorders
Dobs AAmerican Academy of HIV Medicine, Washington, DC2007
Eighth International Congress of Andrology Free Papers
Chapter: Topical Testosterone Replacement Therapy Based on Skin Penetration Enhancer SEPA.
Chan T, Dobs A, McMurray J, Pino J, Silverman M, Swerdloff REditors: Kim S-C, Grootegoed JA, Chemes HE.Seoul, Korea2005
Herbal and Traditional Medicine: Molecular Basis of Health.
Chapter: Clinical Trials for Herbal Extracts. Dietary Supplements.
Page 53 - 73Asher B, Dobs ASEditors: Packer L, Ong CN, Halliwell B.CRC Press, Boca Raton, FL2004
Workshop on the Safety of Black Cohosh in Clinical Studies.
Chapter: Summary and Next Steps.
Miller H, Dobs A, Chesney MNational Institutes of Health, Bethesda, MD2004
Principles of Gender-Specific Medicine.
Chapter: Section 10: Endocrinology and Metabolism.
Editors: Legato M (ed); Dobs AS (section editor).Elsevier Academic Press, New York, NYEdition 1st,2004
Principles of Gender-Specific Medicine.
Chapter: Testosterone Replacement Therapy in Men and Women.
El-Maouche D, Dobs ASEditors: Legato M.Elsevier Academic Press, New York, NYEdition 1st,2004
Endocrinology of HIV.
Chapter: Female hypogonadism in HIV.
Basaria S, Dobs ASEditors: Lo Presti JS.2003
Androgens in Health and Disease.
Chapter: Androgens and the hematopoietic system.
Page 233 - 242Basaria S, Dobs ASEditors: Bagatell CJ, Bremner WJ.Humana Press, Totowa, NJ2003
The Johns Hopkins Women’s Health Guide.
Chapter: The Endocrine System.
Dobs ASEditors: Callan NA.Harper Collins, New York, NY2002
ACP Medicine.
Chapter: CAM in Internal Medicine. Scientific American.
Asher BH, Dobs ASWebMD Professional Publishing, New York, NY2002
Skeletal Muscle: Pathology, Diagnosis and Management of Disease.
Chapter: HIV Myopathy: Pathology, Diagnosis and Treatment.
Page 207 - 218Basaria S, Dobs ASEditors: Preedy VR, Peters TJ.Greenwich Medical Media, London2002
2000 Andropause Consensus Conference.
Chapter: Androgen Deficiency in Young Men.
Dobs ASEndocrine Society2002
Cutaneous Medicine.
Chapter: Cutaneous manifestations of endocrine diseases.
Page 413 - 451Boyne M, Dobs AS, Krasner AS, Provost TTEditors: Provost TT, Flynn JA.BC Decker Inc, Hamilton, Ontario, Canada2001
AIDS Quality of Life Monograph.
Chapter: Sexual dysfunction in HIV infected individuals.
Dobs ASEditors: Miles S.Univ Massachusetts, Anherst, MA1999
Geneva AIDS Conference
Chapter: Endocrine Abnormalities in HIV-associated wasting.
Dobs AS1998
Advances in Medicine Series.
Chapter: Physiologic Effects of Testosterone Replacement Therapy.
Dobs AS1997
The Principles and Practice of Medicine.
Chapter: Gonadal Disorders.
Dobs ASEditors: Stobo JD, Hellmann DB, Ladenson PW, Petty BG, Traill TA.Appleton & Lange, Norwalk, CTEdition 23rd,1996
Clinical Aspects of Aging.
Chapter: Peripheral vascular disease in the elderly.
Page 117 - 124Dobs ASEditors: Reichel W.Williams & Wilkins, Baltimore, MDEdition 4th,1995
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Lectures

Hypogonadism: Sorting through the Controversies
2019 ACP Internal Medicine Meeting, Philadelphia - 4/12/2019
Clinical Research
Quong-Chou, China - 1/1/2012
NIDA Symposium on Metabolic Effects of Drug Use
Denver, CO - 1/1/2012
Testosterone and Cardiovascular Disease
Miami, FL - 1/1/2010
The Gonadal Axis in DMD: Diagnosis and Treatment Options.
Baltimore, MD - 1/1/2010
Aging and Testosterone Treatment
Monte Carlo, Monaco - 1/1/2009
PD5-Inhibitors and Heart Disease
Toronto, Canada - 1/1/2008
Hypogonadism and Chronic Illness
1/1/2008
Complications of Prostate Cancer
Royal Academy of London, London - 1/1/2007
Testosterone Therapies in the US
Paris - 1/1/2006
Hypogonadism and HIV
Dublin - 1/1/2005
Androgens and Chronic Illness
1/1/2005
Fish Oils and Cardiovascular Disease
Chinese Traditional Medicine Academy, Beijing, China - 1/1/2005
Male Androgen: Age and Impact
1/1/2005
Testosterone Therapy: Expanding Options for the Treatment of Hypogonadism
1/1/2004
Cancer Integrative Medicine/NCI
Chicago, IL - 1/1/2003
Clinical Trial Management
1/1/2003
Hypogonadism and Sexual Dysfunction
1/1/2003
Complementary and Alternative Medicine
Newport Beach, CA - 1/1/2003
Endocrine Complications of HIV/AIDS and Substance Abuse, and Interventions: USA.
Bethesda, MD - 1/26/2001
Testosterone Replacement Therapy
JHU, Baltimore, MD - 1/1/2001
New Options for Testosterone
1/1/2001
Physiology of Testosterone in Women
1/1/2001
Trends in CAM
Taiwan Medical Center, Taiwan - 1/1/2001
Opportunities for Drug Recovery in Women’s Health
1/1/2001
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Other

Testosterone and Mortality: An Expert Interview with Adrian S. Dobs, MD MHS
Dobs AS, CME Activity
http://cme.medscape.com/viewprogram/8661
1/30/2008
Emerging Evidence and Future Directions in Treating Hypogonadism.
Dobs AS, Hayes FJ, Monograph, TestosteroneUpdate
www.primaryperspective.org/tu/endo_supplement.pdf
1/1/2008
Healthy Living Special Report: The Uses and Misuses of Testosterone Therapy: Johns Hopkins Professor Adrian Dobs, MD talks about testosterone replacement therapy. Heal...
Dobs AS, Healthy Living
www.johnshopkinshealthalerts.com/reports/healthy_living/547-1.html
1/7/2007
Testosterone therapy for the treatment of hypogonadism. A continuing medical education self study activity.
Anawalt BD, Cunningham G, Dobs AS, Monograph; Symposium; Endocrine Society
1/1/2004
Video, Pros and Cons of Male Hormone Replacement Therapy
Dobs AS, CBS Evening News
1/1/2002
Testosterone Replacement Therapies (Internet-Based)
Dobs AS, Brazilian Society of Endocrinology: Endocrine Congress
1/1/2001
Hypogonadism
Dobs AS, Ask the Expert
1/1/1998
Androderm (Testosterone Transdermal System).
Ashworth L, Dobs AS, Ott J, Meikle W, Am Pharmaceutical Assoc New Product Bulletin
1/1/1996
Hormone Replacement Therapy (Film)
Dobs AS, Ivanhoe Scientific Films
1/1/1996
Testosterone replacement in elderly men.
Macalpin J, Dobs AS, Monograph; Linthicum, MD; American Urological Association
1/1/1996
Testosterone in the Elderly (Film)
Dobs AS, The Today Show
1/1/1996
Video on Male Hypogonadism distributed with all prescriptions of Androderm-SmithKline Beecham
Dobs AS
1/1/1995
Klinefelter Syndrome (Film)
Dobs AS, CNN
1/1/1992
Male Hypogonadism (Film)
Dobs AS, 20-20 TV Show
1/1/1990
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Press Mentions

How Fat Phobia Impacts Patients and DoctorsAugust 5th, 2021
Why It’s Harder for Many Transgender People to Access (And Trust) COVID-19 VaccinesMay 18th, 2021
Thank You for All You Do: Endocrinology and HematologyJuly 10th, 2020
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