AdamLernerMD

PubMed

• 14 citations
  Anti-inflammatory effects of novel barbituric acid derivatives in T lymphocytes.
  Chenjia Xu, Arlene R. Wyman, Manal A. Alaamery, Shannon A. Argueta, F. Douglas Ivey
  International Immunopharmacology. 2016-09-01
• 81 citations
  p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.
  Takaya Gotoh, Dongpo Cai, Xuejun Tian, Larry A. Feig, Adam Lerner
  The Journal of Biological Chemistry. 2000-09-29
• 368 citations
  Brentuximab vedotin or physician's choice in CD30-positive cutaneous T-cell lymphoma (ALCANZA): an international, open-label, randomised, phase 3, multicentre trial
  H. Miles Prince, Youn H. Kim, Steven M. Horwitz, Reinhard Dummer, Julia Scarisbrick
  Lancet. 2017-08-05

Journal Articles

• AND-34/BCAR3 augments the ability of p130Cas to bind the Src SH3 domain in a BCAR3-p130Cas complex-dependent manner  
  Makkinje A, VandenBorre P, Near RI, Patel P and Lerner A, J. Biol. Chem, 1/1/2012
• Primary cutaneous CD56 positive lymphoma: a diagnostic conundrum in an unusual case of lymphoma  
  Schieke SM, Sharaf M, Lerner A, Runger T, Mahalingam M, J. Cutan. Pathol, 1/1/2012
• Complete response of metastatic hidradenocarcinoma to capecitabine  
  Lerner A, Beckford A, Ugent S, Goldberg L, Jalisi S and Demierre MF, Archives of Derm, 1/1/2011
• Chemotherapy as treatment for colocolonic intussusception associated with acquired immunodeficiency-related lymphoma  
  Lerner A, Soto J and Rosen J, Surgery, 1/1/2011
• AND-34/BCAR3 is required for structural integrity of the adult mouse lens  
  Near RI, Smith RS, Toselli PA, Freddo T, Bloom A, Vanden Borre P, Seldin D and Lerner A, Molecular Vision, 1/1/2009
• Structural insights into the association between BCAR3 and Cas family members; an atypical complex implicated in anti-oestrogen resistance  
  Garron ML, Arsenieva D, Zhong J, Bloom A, Lerner A, O’Neill GM and Arold ST, J. Mol. Biol, 1/1/2009
• Successful adjuvant treatment of recalcitrant mucous membrane pemphigoid with anti-CD20 antibody Rituximab  
  Taverna JA, Lerner A, Bhawan J, Demierre MF, J.Drugs Dermatol, 1/1/2007
• Infliximab as therapy for idiopathic hypereosinophilic syndrome  
  Taverna JA, Lerner A, Goldberg L, Werth S, Demierre MF, Arch. Dermatol, 1/1/2007
• Characterization of AND-34 function and signaling  
  Felekkis KN, Quilliam LA and Lerner A, Methods in Enzymology, 1/1/2006
• Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies  
  Lerner A and Epstein P, Biochemical Journal, 1/1/2006
• Vinca alkaloids vs. taxanes as therapy in lymphoid malignancies: Do our experimental models obscure our knowledge of how these drugs really work?  
  Lerner A and Andrea N, Cancer Invest, 1/1/2005
• Immunologic recovery after autologous blood stem cell transplantation in patients with AL-amyloidosis  
  Akpek G, Lenz G, Lee SM, Sancharawala V, Wright DG, Colarusso T, Waraska K, Lerner A, Vosburgh E, Skinner M and Comenzo RL, Bone Marrow Transplantation, 1/1/2001
• P130Cas regulates the activity of AND-34, a novel Ral, Rap1 and R-Ras guanine nucleotide exchange factor  
  Gotoh T, Cai D, Feig L and Lerner A, J. Biol. Chem, 1/1/2000
• The cAMP signaling pathway as a therapeutic target in lymphoid malignancies  
  Lee R, Kim DH and Lerner A, Leukemia and Lymphoma, 1/1/2000
• AND-34, a novel p130Cas-binding thymic stromal cell protein induced by inflammatory cytokines  
  Cai D, Clayton LK, Smolyar A and Lerner A, J. Immunol, 1/1/1999
• Pre-TCR signaling components trigger transcriptional activation of a rearranged TCR alpha gene locus and silencing of the pre-TCR alpha locus: implications for intrath...  
  Koyasu S, Clayton LC, Lerner A, Heiken H, Parkes A, Reinherz EL, Int. Immunol, 1/1/1997
• Cross-linking of T cell receptors on double positive thymocytes induces a cytokine-mediated stromal activation process linked to cell death  
  Lerner A, Clayton LC, Mizoguchi E, Ghendler Y, Koyasu S, Bhan AK and Reinherz EL, EMBO J, 1/1/1996
• Targeted disruption within the CD3 zeta/eta/phi/Oct-1 locus in mouse  
  Koyasu S, Hussey RE, Clayton LK, Lerner A, Pederson R, Delaney-Heiken P, Chau F and Reinherz EL, EMBO J, 1/1/1994
• CD3 zeta/eta/theta locus is colinear with and transcribed antisense to the gene encoding the transcription factor Oct-1  
  Lerner A, D’Adamio L, Diener AC, Clayton LK and Reinherz EL, J Immunol, 1/1/1993
• Type 4 cAMP phosphodiesterase as a therapeutic target in chronic lymphocytic leukemia  
  Kim, D.H. and Lerner A, Blood, 1/1/1992
• T cell receptor isoforms  
  Clayton LK, Lerner A, Diener AC, Hussey RE, Koyasu S, and Reinherz EL, Int. J. Cancer, 1/1/1992
• Differential regulation of T-cell receptor processing and surface expression affected by CD3 theta, an alternatively spliced product of the CD3 zeta/eta gene locus  
  Clayton LK, Diener AC, Lerner A, Tse A, Koyasu S and Reinherz EL, J.Biol.Chem, 1/1/1992
• Human genomic sequences corresponding to murine CD3 eta-related transcripts: lack of expression of homologous human products  
  Lerner A, Diener AC, Reinherz EL, Clayton LK, Eur J Immunol, 1/1/1992
• Etoposide, doxorubicin, and cisplatin chemotherapy for advanced gastric adenocarcinoma: results of a phase II trail  
  Lerner A, Gonin R, Steele GD, Mayer RJ, J. Clin. Oncol, 1/1/1992
• PGP-1 T lymphocytes accumulate with age in mice and respond poorly to concanavalin A  
  Lerner A, Yamada A, Miller R, Eur J Immunol, 1/1/1989
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Books/Book Chapters

• Goldman’s Cecil Medicine 
  Chapter: Primary and metastatic malignant bone lesions 
  Lerner A and Antman KEdition 24th,2011
• ACP Medicine 
  Chapter: Sarcomas of soft tissue and bone 
  Lerner A and Antman KB C Decker Publishers2011
• Cyclic Nucleotide Phosphodiesterases in Health and Disease 
  Chapter: Role of Phosphodiesterases in apoptosis 
  Page 559 - 582Lerner A, Moon E and Tiwari SEditors: J Beavo, S Francis and M Houslay.CRC Press2006
• Current Practice in Medicine 
  Chapter: Bone and soft tissue sarcomas 
  Lerner A, Elias AChurchill Livingstone Inc., New York, N.Y.Edition 2nd ,1999
• Mol. Basis of Immune Resp. 
  Chapter: T cell receptor isoforms during thymic differentiation 
  Reinherz EL, Lerner A, Diener AC, Hussey R, Koyasu S and Clayton LKEditors: H. Nariuchi.Academic Press1993
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Abstracts/Posters

• Successful Transition from Bortezomib Subcutaneous (SubQ) to Generic Intravenous (IV) Bortezomib: Cost Savings Initiative with Global Economic Impact
  Adam Lerner, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019