AaronBWaxmanMDPhD

PubMed

• 85 citations
  NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension
  Andriy O. Samokhin, Thomas E. Stephens, Bradley M. Wertheim, Rui-Sheng Wang, Sara O. Vargas
  Science Translational Medicine. 2018-06-13
• 134 citations
  Noninvasive Assessment of Murine Pulmonary Arterial Pressure Validation and Application to Models of Pulmonary Hypertension
  Helene Thibault, Baptiste Kurtz, Michael J. Raher, Rahamthulla S. Shaik, Aaron B. Waxman
  Circulation. Cardiovascular Imaging. 2010-03-01
• 56 citations
  Sotatercept for the treatment of pulmonary arterial hypertension: PULSAR open-label extension.
  Marc Humbert, Vallerie McLaughlin, J Simon R Gibbs, Mardi Gomberg-Maitland, Marius M Hoeper
  The European Respiratory Journal. 2023-01-01

Journal Articles

• Pulmonary vascular morphology as an imaging biomarker in chronic thromboembolic pulmonary hypertension  
  Rahaghi, F.N., Ross, J.C., Agarwal, M., Gonzalez, G., Come, C.E., Diaz, A., Sanchez-Ferrero, G.V., Andetta, H., Jose Estapar, R.S., Waxman, A.B., Washko, G.R., Pulmonary Circulation, 1/1/2016
• Portopulmonary Hypertension, Challenges in Diagnosis and Management  
  Troy P, Waxman AB, Therapeutic Advances in Gastroenterology, 1/1/2009
• Plasma Gelsolin is a Marker and Therapeutic Agent in Animal Sepsis  
  Lee PS, Waxman AB, Cotich KL, Chung SW, Perrella MA, Stossel TP, Critical Care Medicine, 1/1/2007
• Preoperative Intravenous Epoprostenol Prior to Surgical Repair of a Ventricular Septal Defect in an Adult With Eisenmenger's Syndrome  
  Schmidt S, Waxman AB, Chest, 1/1/2006
• Hemodynamic Impact of Mechanical Ventilation in ARDS  
  Papa J, Sasidhar M, Waxman AB, Clinical Pulmonary Medicine, 1/1/2003
• Pulmonary Hypertension: Diagnosis and Management  
  Budhiraja R, Waxman AB, Resident and Staff Physician, 1/1/2002
• Cellular and Molecular Mechanisms of Lung Injury and Repair  
  Sethi J, Waxman AB, Clinical Pulmonary Medicine, 1/1/2001
• Invited commentary on Prevention of Ventilator-associated Pneumonia by Oral Decontamination A Prospective, Randomized, Double blind, Placebo-controlled Study  
  Waxman AB, Journal Club of the Assembly on Critical Care of American Thoracic Society Respiratory Failure and Mechanical Ventilation, 1/1/2001
• Invited commentary on the comfort of breathing: A study with volunteers assessing the influence of various modes of assisted ventilation  
  Waxman AB, Journal Club of the Assembly on Critical Care of American Thoracic Society Respiratory Failure and Mechanical Ventilation, 1/1/2000
• Invited commentary on Prospective randomized trial comparing pressure-controlled ventilation and volume-controlled ventilation in ARDS Respiratory Failure and Mechanic...  
  Waxman AB, Journal Club of the Assembly on Critical Care of the American Thoracic Society, 1/1/2000
• Practical Use of the Pulmonary Artery Catheter in the ICU  
  Waxman AB, Sasidhar M, Journal of Respiratory Diseases, 1/1/1999
• Critical Review of Pulmonary Artery Catheter Use in the ICU  
  Waxman AB, Matthay M, Pulmonary and Critical Care Update, 1/1/1998
• Cytomegalovirus as a Pulmonary Pathogen  
  Goldie SJ, Waxman AB, Chest, 1/1/1997
• Evidence of a role for the vomeronasal organ in social hierarchy in feedlot cattle  
  Klemm WR, Sherry CJ, Sis RF, Schake LM and Waxman AB, Applied Animal Behavior Science, 1/1/1980
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Books/Book Chapters

• Scientific American Medicine. 
  Chapter: Medical Management of Pulmonary Embolism. 
  Schissler, A.J., Waxman, A.B.Editors: Stone, PH, Lewis, EF.Decker Intellectual Properties, Hamilton, Ontario, Canada2018
• Patients Survival Guide 
  Chapter: Chapter 7-More on PH Drugs 
  Waxman ABPulmonary Hypertension AssociationEdition 5th,2016
• Pulmonary Hypertension; Basic Science to Clinical Medicine. 
  Chapter: Assessing Disease State in the Pulmonary Vasculature in Clinical Practice and Research. 
  Page 291 - 229Agarwal, M., A.B. WaxmanEditors: Maron, Bradley A., Zamanian, Roham T., Waxman, Aaron B..Springer, New York, NY2016
• The Diagnosis and Management of Pulmonary Hypertension. 
  Chapter: Cardiopulmonary exercise testing in pulmonary hypertension. 
  Page 265 - 301Systrom, D.M., A.B. WaxmanEditors: J.R. Klinger and R.P. Frantz.Springer-Verlag, New York, NY2015
• Harrison's Principles of Internal Medicine 
  Chapter: Pulmonary Hypertension 
  Page 1655 - 1661Waxman, A.B., J. LoscalzoEditors: D.L. Kasper, A.S. Fauci et al.McGraw Hill Education, New York, NYEdition 19th,2015
• The Right Heart 
  Chapter: The normal and abnormal right heart: Introduction to a clinical classification. 
  Page 1 - 5Mehra, M. R., M.H.Park, M.J. Landzberg, Waxman A.B.Editors: S.P. Gaine, R. Naejie, and A.J. Peacock.Springer-Verlag, London, United Kingdom2014
• Asthma; Comorbidities, Coexisting Conditions, & Differential Diagnosis. 
  Chapter: Pulmonary Hypertension - Coexisting and Differential Diagnosis. 
  Page 215 - 231Waxman, A.B., and K.A. SmithEditors: R.F. Lockey and D.K. Ledford.Oxford University Press, New York, NY2014
• Aging and Lung Disease: A Clinical Guide, Respiratory Medicine 
  Chapter: Pulmonary Hypertension in Older Patients. 
  Smith, K.A., Waxman, A.B.Editors: M. Pisani.Springer Science+Business Media, LLC2012
• Introduction to Bronchoscopy 
  Chapter: Flexible Bronchoscopy: Indications, Contraindications, and Consent. 
  Page 75 - 85Waxman ABEditors: Armin Ernst A.Cambridge University Press, New York, NY2008
• Respiratory Emergencies. 
  Chapter: Pulmonary Vascular Physiology. 
  Page 31 - 41Mojica JE, Waxman ABEditors: Fein A, Kamholz AS, Ost D.Edward Arnold Publishers, Ltd., London, United Kingdom2006
• Patient Care Manual 
  Waxman ABMassachusetts General Hospital2005
• Acute Respiratory Distress Syndrome. 
  Chapter: Pathogenesis of Acute Lung Injury: Experimental Studies. Chapter 6. 
  Page 115 - 146Manzo ND, Waxman ABEditors: Matthay M.Markel Dekker, New York, NY2003
• NATO ASI Series, Etiology and Treatment of Acute Lung Injury: From Bench to Bedside. 
  Chapter: Transgenic Modeling of Mechanisms of Protection in Acute Lung Injury 
  Page 140 - 151Waxman AB, Zhu Z, Lee CG, Elias JAEditors: Matalon S, Sznajder JI.IOS Press, NATO Science Series, Series, BV Amsterdam, Netherlands2000
• Advanced Therapy in Thoracic Surgery. 
  Chapter: Acute Respiratory Distress Syndrome 
  Page 1 - 13Siegel M, Waxman ABEditors: Franco K, Putnam JB.B.C. Decker Inc., Hamilton, Ontario, Canada1998
• Critical Care Pearls. 
  Chapter: A 51-year-old woman with a bone marrow transplant and rapidly progressive dyspnea. 
  Page 254 - 256Waxman AB, Matthay RAEditors: Sahn SA, Heffner JE.Hanley & Belfus, Inc., Philadelphia, PAEdition 2nd,1997
• Proceedings of 23rd Symposium Medicum Hoechst on "The Biology of Memory". 
  Chapter: Laser Microscopy of Subcellular Structure in Living Neocortex: Can One See Dendritic Spines Twitch? 
  Page 237 - 256Smith SJ, Cooper MW, Waxman ABEditors: Squire L, Lindenlaub E.1989
• Intrinsic Determinants of Neuronal Form. 
  Chapter: Hippocampal neurons generate natural shapes in cell culture. 
  Page 128 - 140Banker GA and Waxman ABEditors: Lasek R, Black MB.Alan R. Liss, New York, NY1988
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Abstracts/Posters

• Exercise Intolerance in Preload Failure Treated with Pyridostigmine.
  M. Faria Urbina, R. Oliveira, A. Oaklander, A. B. Waxman, D. M. Systrom, American Thoracic Society, San Diego, CA, 1/1/2018
• Right Ventricular-Pulmonary Arterial Uncoupling During Exercise in Pulmonary Hypertension.
  I. Singh, F. N. Rahaghi, M. Faria Urbina, R. K. Oliveira, T. Bachman, A. B. Waxman, D. M. Systrom, American Thoracic Society, San Diego, CA, 1/1/2018
• Impaired Systemic Oxygen Extraction in Treated Exercise Pulmonary Hypertension: A New Engine in an Old Car?
  M. Faria Urbina, R. Oliveira, S. Segrera, L. Lawler, A. B. Waxman, D. M. Systrom, American Thoracic Society, San Diego, CA, 1/1/2018
• Submaximum Exercise Testing to Evaluate Outcomes After Pulmonary Thromboendarterectomy.
  P. Joseph , J. Tracy , H. Mallidi , A. B. Waxman , D. M. Systrom, American Thoracic Society, San Diego, CA, 1/1/2018
• Bardoxolone Methyl Increased eGFR in Patients with Pulmonary Arterial Hypertension Associated with Connective Tissue Disease (The LARIAT Study)
  R. White, C. Meyer, M. Chin, J. P. Feldman, A. Goldsberry, J. W. McConnell, P. A. McCullough, M. O'Grady, V. F. Tapson, F. Torres, A. B. Waxman, R. J. Oudiz, American Thoracic Society, San Diego, CA, 1/1/2018
• Ultrasound-assisted catheter-directed thrombolysis (UACDT) compared with anticoagulation alone for treatment of acute submassive pulmonary embolism.
  A.J. Schissler, R.J. Glynn, P.S. Sobieszczyk, A.B. Waxman, American Thoracic Society, San Diego, CA, 1/1/2018
• A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Subjects with Pulmonary Hypertension...
  A.B. Waxman, V.F. Tapson, P.M. Smith, C.Q. Deng, S.D. Nathan, American Thoracic Society, San Diego, CA, 1/1/2018
• Submaximum exercise testing to evaluate outcomes in pulmonary vasodilator therapy in PAH.
  S. Segrera, P. Joseph, J. Tracy, A. B. Waxman, D. M. Systrom, American Thoracic Society, San Diego, CA, 1/1/2018
• Ranolazine and Right Ventricular Function in Patients with Pulmonary Hypertension
  Y. Han, P. R. Forfia, A. Vaidya, J. A. Mazurek, M. H. Park, G. Ramani, A. B. Waxman, American Thoracic Society, San Diego, CA, 1/1/2018
• 89Zr-Bevacizumab PET Detects Arteriolar Remodeling In Experimental Pulmonary Hypertension
  L.M. Yung, I. Nikolic, M. Park, M.F. Kijewski, S. Wang, T. Dinter, G. Bocobo, J. Paolino, A.P. Belanger, S. Dubey, M. Southwood, N. Morrell, B.A. Maron, A.B. Waxman, M..., American Heart Association, Scientific Sessions, Anaheim, CA, 1/1/2017
• A Sweet Remedy for Severe Pulmonary Arterial Hypertension.
  I. Singh, E. Gay, A.B. Waxman, American Thoracic Society, Washington, DC, 1/1/2017
• CT Measures of Arterial and Venous Geometry in Pre- and Post capillary Pulmonary Hypertension.
  F.N. Rahaghi, R Radhakrishnan, J Minhas, E Ayala, J Ross, R San Jose Estepar, AB Waxman, G.R Washko, American Thoracic Society, Washington, DC, 1/1/2017
• Exercise limit in small fiber axonopathy: an invasive cardiopulmonary exercise test study.
  D.M. Systrom, R.K.F. Oliveira, M.U. Faria, A.B. Waxman, A.L. Oaklander, American Thoracic Society, Washington, DC, 1/1/2017
• Results of Interim Analysis of the Efficacy and Safety of Bardoxolone Methyl in Patients with Pulmonary Arterial Hypertension Associated with Connective Tissue Disease...
  R. Oudiz, C. Meyer, M. Chin, J. Feldman, A. Goldsberry, J. McConnell, P.A. McCullough, M. O’Grady, V. Tapson, F. Torres, A.B. Waxman, R.J. White, American Journal of Respiratory and Critical Care Medicine; American Thoracic Society, Washington, DC, 1/1/2017
• Network Analysis for Diagnosis and Risk Stratification of Cardiopulmonary Patients with Exercise Dysfunction.
  W.M. Oldham, R.K.F. Oliveira, R. Wang, A.R. Opotowsky, B.M. Wertheim, G.A. Alba, C. MacRae, D.M. Rubins, J. Loscalzo, J.A. Leopold, A.B. Waxman, D.M. Systrom, B.A. Maron, American Heart Association, Scientific Sessions, Anaheim, CA, 1/1/2017
• Physiologic Dynamic Right Ventricular Outflow Tract Obstruction During Exercise: clinical implications for exercise echocardiography to identify abnormal pulmonary vas...
  A.C.M.J. van Riel, D.M Systrom, R.K.F. Oliveira, M.J. Landzberg, B.J.M. Mulder, B.J. Bouma, A.M. Shah, A.B. Waxman, A.R. Opotowsky, American College of Cardiology, Chicago, IL, 1/1/2016
• Abnormal Transpulmonary Metabolite Flux In Exercise Induced Pulmonary Arterial Vasculopathy.
  A.B. Waxman, C. Bennett, A.J. Janocha, S.A.A. Comhair, S.C. Kalhan, J. Leopold, S. Erzurum, D.M. Systrom, American Thoracic Society International Conference, San Francisco, CA, 1/1/2016
• Exercise Induced Pulmonary Arterial Hypertension (EIPAH) Exhibits Thrombophilia and Endothelial Activation.
  A.B. Waxman, L. Grove, D.M. Systrom, J. Leopold, R. Dweik, G. Heresi, S. Erzerum, M. Olman, American Thoracic Society International Conference, San Francisco, CA, 1/1/2016
• Fick principle determinants of the 6minute walk test (6MWT) distance.
  R. Badr Eslam, R.K. Oliveira, J.A. Tracy, A.L. Karin, M. Agarwal, A.B. Waxman, D. Systrom, American Thoracic Society International Conference, San Francisco, CA, 1/1/2016
• Exercise pulmonary hypertension in fibrotic interstitial lung disease with borderline resting mean pulmonary arterial pressure.
  R.K.F. Oliveira, J.A. Tracy, A.L. Karin, A.B. Waxman, D.M. Systrom, American Thoracic Society International Conference, San Francisco, CA, 1/1/2016
• Prevalence of exercise pulmonary hypertension in borderline resting pulmonary hypertension.
  R.K.F. Oliveira, J.A. Tracy, A.L. Karin, A.B. Waxman, D.M. Systrom, American Thoracic Society International Conference, San Francisco, CA, 1/1/2016
• Pyridostigmine for Exercise Intolerance Treatment in Preload Failure.
  R.K.F. Oliveira, J.A. Tracy, A.L. Karin, A.B. Waxman, D.M. Systrom, American Thoracic Society International Conference, San Francisco, CA, 1/1/2016
• The Long-Term Outcomes in Patients with Exercise-Induced Pulmonary Arterial Hypertension.
  W. Huang, D.M. Systrom, A.B. Waxman, American Thoracic Society International Conference, San Francisco, CA, 1/1/2016
• Early Pulmonary Vascular Dysfunction in Exercise-induced Heart Failure with Preserved Ejection Fraction: Prognostic Implications.
  W. Huang, R.K.F. Oliveira, D.M. Systrom, H. Lei, A.B. Waxman, American Thoracic Society International Conference, San Francisco, CA, 1/1/2016
• Changes in intraparenchymal arterial and venous blood distribution quantified from ct scans in pulmonary hypertension with elevated wedge pressure.
  Minhas J, Rahaghi F, Radhakrishnan R, Ross J, Waxman A, San Jose Estepar R and Washko G, Chest, 1/1/2016
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Lectures

• Totally Implantable Subcutaneous Devices for Continuous Prostanoid Delivery. 
  University of California, San Francisco, San Francisco, CA - 1/1/2018
• Explaining unexplained exertional dyspnea: Application of the full Fick Principle. 
  Norwalk Hospital, Norwalk, CT - 1/1/2018
• Invasive cardiopulmonary exercise testing to predict outcomes in heart failure preserved ejection fraction. 
  University of Utah School of Medicine, Salt Lake City, UT - 1/1/2018
• What is new in Pulmonary Arterial Hypertension. 
  Harvard Medical School and the Brigham and Women’s Hospital, Boston, MA - 1/1/2018
• Unexplained exertional intolerance: Dynamic assessment of cardiopulmonary and metabolic function during invasive exercise testing. 
  Loma Linda, CA - 1/1/2018
• Treprostinil Administered Using a Fully Implantable Programmable Intravascular Delivery System. 
  Intermountain Medical Center, Murray, UT - 1/1/2018
• Is there a therapeutic opportunity for prostacyclins in patients with PH secondary to primary pulmonary disease? 
  United Kingdom - 1/17/2017
• Novel Therapeutic Approaches to the Treatment of Pulmonary Hypertension. 
  Harvard Medical School and the Brigham and Women's Hospital, Boston, MA, 2016, 2017 - 1/1/2017
• Practical use of different methods of exercise testing in PH, including 6-minute walk test, cardiopulmonary exercise test, and treadmill exercise. 
  Berlin, Germany - 1/1/2017
• Invasive Exercise Testing; The full Fick equation. 
  Glenview, IL - 1/1/2017
• Pulmonary Arterial Hypertension; Clinical Presentation, Diagnosis, and Emerging Therapies. 
  Boston, MA - 1/1/2017
• Explaining unexplained exertional dyspnea. 
  Metrowest Medical Center, Natick, MA - 1/1/2017
• Twenty Years of Therapy for PAH; Where are we now, and where are we headed. 
  Havana, Cuba - 1/1/2017
• Imaging the Right Ventricle During Exercise 
  Miami, FL - 1/1/2017
• Clinical Trials for Exercise Pulmonary Hypertension Are Warranted 
  Bethesda, MD - 1/1/2016
• Exercise in the Diagnosis of Patients without/maybe with/with Pulmonary Hypertension. 
  University of Pennsylvania School of Medicine, Philadelphia, PA - 1/1/2016
• Abnormal Transpulmonary Metabolite Flux In Exercise Induced Pulmonary Arterial Vasculopathy. 
  San Francisco, CA - 1/1/2016
• Updates in Pathophysiology, Genetics, and Medical Management of Idiopathic Pulmonary Hypertension 
  Harvard Medical School, Boston, MA - 1/1/2016
• ExerciseInduced Pulmonary Hypertension; Isit areal disease? 
  Yale University School of Medicine, New Haven, CT - 1/1/2016
• Invasive-CPET: Dynamic Assessment of Cardiovascular, Respiratory, and Metabolic Function During Exercise 
  Glenview, IL - 1/1/2016
• Pulmonary Arterial Hypertension; Clinical Presentation, Diagnosis, and Approach to Therapy. 
  Chongqing Medical University, Chongqing, China - 1/1/2016
• Unexplained Dyspnea; Diagnosis based on physiology. 
  Cambridge, MA - 1/1/2016
• ChronicThromboembolicPulmonaryHypertension -Evaluation and Management. 
  Dartmouth Medical Center, Hitchcock, NH - 1/1/2016
• Recent advances in Pulmonary Arterial Hypertension; Translating preclinical studies into clinical practice. 
  Fuwai Hospital, Beijing, China - 1/1/2016
• Clinical Case of the Month; 61 year old woman with dyspnea on exertion. 
  Brigham and Women's Hospital, Boston, MA - 1/1/2016
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Other

• Approach to the patient with Dyspnea. 
  Badr Eslam, R., Waxman, A.B., Scientific American Medicine, Pulmonary Medicine, Decker
  https://www.deckerip.com/decker/scientific-american-medicine/chapter/115/
  1/8/2016
• Advanced Prostanoid Therapy in PAH: The Time to Be Proactive Is Now! 
  Waxman, AB, Chakinala, MM, Frantz, RP
  http://www.medscape.org/viewarticle/755179
  1/22/2011
• Diagnosis to Treatment: Facing the Challenges of Pulmonary Arterial Hypertension. 
  Waxman AB, Clinical Case Challenge
  1/1/2010
• Pulmonary Arterial Hypertension, Diagnostic Challenges and Selecting Optimal Therapy 
  Waxman AB, MedScape CME
  1/1/2008
• Invited commentary on Differential effects of sustained inflation recruitment maneuvers on alveolar epithelial and lung endothelial injury. 
  Waxman AB, Respiratory Failure and Mechanical Ventilation, Journal Club of the Assembly on Critical Care of the
  http://www.thoracic.org/assemblies/cc/ccjcframe.html
  1/1/2005
• Invited commentary on Effect of Hemofiltration on Hemodynamics, Lung Inflammation and Pulmonary Edema in a Canine Model of Acute Lung Injury." 
  Waxman AB, Respiratory Failure and Mechanical Ventilation, Journal Club of the Assembly on Critical Care of the
  http://www.thoracic.org/assemblies/cc/ccjcframe.html
  1/1/2004
• Invited commentary on Tidal Volume Increases Do Not Affect Alveolar Mechanics in Normal Lung But Cause Alveolar Overdistension And Exacerbate Alveolar Instability afte... 
  Waxman AB, Journal Club of the Assembly on Critical Care of the American Thoracic Society
  http://www.thoracic.org/assemblies/cc/ccjcframe.html
  1/1/2003
• Invited commentary on Noninvasive Ventilation during Persistent Weaning Failure; A Randomized Controlled Trial. Respiratory Failure and Mechanical Ventilation 
  Waxman AB, Journal Club of the Assembly on Critical Care of the American Thoracic Society
  http://www.thoracic.org/assemblies/cc/ccjcframe.html
  1/1/2003
• Invited commentary on Oscillations and Noise, Inherent Instability of Pressure Support Ventilation? Respiratory Failure and Mechanical Ventilation 
  Waxman AB, Journal Club of the Assembly on Critical Care of the American Thoracic Society
  http://www.thoracic.org/assemblies/cc/ccjcframe.html
  1/1/2002
• The Role of Cell Interactions in the Development of Dendritic Arbors of Hippocampal Neurons in Culture [doctoral thesis] 
  Waxman, AB
  Albany Medical College, Albany, NY - 1/1/1988
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