AaronDavidVinyMDMS

PubMed

• 180 citations
  Genetic alterations of the cohesin complex genes in myeloid malignancies
  Swapna Thota, Aaron D. Viny, Hideki Makishima, Barbara Spitzer, Tomas Radivoyevitch
  Blood. 2014-09-11
• 140 citations
  DNA methylation disruption reshapes the hematopoietic differentiation landscape
  Franco Izzo, Stanley Chun-Wei Lee, Asaf Poran, Ronan Chaligne, Federico Gaiti
  Nature Genetics. 2020-03-23
• 105 citations
  Clinical and molecular predictors of response and survival following venetoclax therapy in relapsed/refractory AML
  Maximilian Stahl, Kamal Menghrajani, Andriy Derkach, Alexander Chan, Wenbin Xiao
  Blood Advances. 2021-03-09

Journal Articles

• Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis  
  Viny AD, Ott CJ, Spitzer B, Rivas M, Meydan C, Papalexi E, Yelin D, Shank K, Reyes J, Chiu A, Romin Y, Boyko V, Thota S, Maciejewski JP, Melnick A, Bradner JE, Levine RL, Journal of Experimental Medicine, 1/5/2015
• T/B or not T/B: High frequency of B-cell dyscrasias in T-LGL leukemia  
  Pawarode A and Baer M, Leukemia & Lymphoma, 1/1/2008
• Childhood Cancer Survival: Racial Disparities Persist  
  Viny, AD, Internal Medicine News, 1/15/2007
• Investigators and advocates hunt for collaboration and smart funding  
  Viny, AD and Maciejewski JP, The New Physician, 1/1/2007
• Racial Disparity in Cancer Survival Pronounced in Older Adolescents and Young Adults  
  Viny, AD, Cancer Watch, 1/1/2007
• Racial Gap Widens for Young Adults with Leukemia, Lymphoma  
  Viny, AD, The Cleveland Plain Dealer, 1/15/2006
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Books/Book Chapters

• Cancer epidemiology in older adolescents and young adults 15 to 29 years of age, including SEER incidence and survival: 1975-2000 
  Chapter: Introduction 
  Page 1 - 14Cancer epidemiology in older adolescents and young adults 15 to 29 years of age, including SEER incidence and survival: 1975-2000Editors: Bleyer A, O’Leary M, Barr R, Ries LAG.National Cancer Institute, Bethesda, MD2006

Abstracts/Posters

• PRMT5 Inhibition Modulates E2F1 Methylation and Gene Regulatory Networks Leading to Therapeutic Efficacy in JAK2VF Mutant MPN
  Aaron D Viny, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• RAS Mutations Are Independently Associated with Decreased Overall Survival and Event-Free Survival in Patients with AML Receiving Induction Chemotherapy
  Aaron D Viny, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Single Cell DNA Sequencing Identifies Combinatorial Mutation Patterns and Clonal Architecture in Myeloid Malignancies
  Aaron D Viny, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Combinatorial Genetics Uncovers Novel Targets for the Treatment of Npm1/Cohesin Mutated AML
  Aaron D Viny, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Recurrecnt Mutations in CCND3 Confer Clinical Resistance to FLT3 Inhibitors
  Smith CC, Viny AD, Massi ES, Kandoth C, Socci ND, Hsu H, West, B, Bollag G, Taylor BS, Levine RL, Shah NP, Blood, 1/1/2015
• Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis
  Viny AD, Ott CJ, Spitzer B, Rivas M, Meydan C, Papalexi E, Yelin D, Shank K, Reyes J, Chiu A, Romin Y, Boyko V, Thota S, Maciejewski JP, Melnick A, Bradner JE, Levine RL, Blood, 1/1/2015
• PHF6 – Somatic Mutations and their Role in Pathophysiology of MDS and AML
  Przychodzen B, Gu X, You D, Hisch CM, Clemente MJ, Viny AD, Levine RL, Haferlach T, Maggendorfer M, Sekeres MA, Carraway HE, Nazha A, Enane F, Maciejewski JP, Blood, 1/1/2015
• Predictors of overall survival in patients diagnosed with desmoplastic small round cell tumor (DSRCT)
  Shoushtari AN, Qin LX, Kuk D, Magnan HD, Modak S, Wolden SL, Cho EJ, Pallos V, Grubman O, Viny AD, Carvajal RD, Chi, P, D’Angelo SP, Dickson MA, Keohan ML, Tap, WD, Le..., J Clin Oncol, 1/1/2014
• The Impact of Clonal Architecture of IDH1 and IDH2 Mutant Cases on the Biology of Myeloid Malignancies
  Thota S, Makishima H, Przychodzen BP, Viny AD, Patel BJ, Radivoyevitch T, Sekeres MA, Carraway HE, Haferlach T, Ogawa S, Maciejewski JP, Blood, 1/1/2014
• Utility of Combined DNA and RNA Next Generation Sequencing in Leukemias for Identification of Prognostic and Therapeutically Relevant Genomic Alterations in Clinical P...
  Coombs CC, Viny AD, He J, Kobos R, Lipson D, Shukla N, Knapp KM, Otto G, Abdel-Wahab O, Stein EM, Rampal RK, Miller, VA, Dogan A, van den Brink MRM, Armstrong SA, Step..., Blood, 1/1/2014
• Optimizing the therapy of desmoplastic small round cell tumor: Combined experience from the two major cancer centers
  Subbiah V, Viny AD, Anderson P, Hayes-Jordan A, Qiao W, Benjamin RS, Maki RG, Ludwig J, J Clin Oncol, 1/1/2012
• Genetic and Functional Investigation of Germline JAK2 Alleles that predispose to Myeloproliferative Neoplasms
  Schram AM, Xu X, Kilpivaara O, Mukherjee S, Viny AD, Guryanova O, Klein RJ, Levine RL, Blood, 1/1/2011
• Clonotype Switching Indicates Propensity for Clonal Outgrowth From Diverse Components of the T Cell Repertoire In T Cell Large Granular Lymphocyte Leukemia
  Clemente M, Wlodarski M, Viny AD, Shaik M, Bejanyan N, Mohan S, Makishima H, Hsi E, Paquette R, Loughran TJ, Maciejewski JP, Blood, 1/1/2010
• Various Abnormalities at Chromosome 7 Carry Distinct Biologic and Prognostic Implications in myelodysplastic/myeloproliferative syndromes and related marrow failures
  Viny AD, Pryzchodzen B, O’Keefe C, Makishima H, Sugimoto Y, Mohan S, Wlodarski M, Kojima S, Sekeres M, Maciejewski JP, Blood, 1/1/2010
• Impact of MICA and Other Immunogenetic Polymorphisms On Clinical Presentation of T Cell Large Granular Lymphocyte Leukemia
  Lazaryan A, Bejanyan N, Viny AD, Askar M, Burnette PK, Maciejewski JP, American Society of Hematology, 1/1/2009
• Expression of MICA by Granulocytes in Neutropenia due to Large Granular Lymphocyte Leukemia Points towards Cytotoxicity Exerted via NKG2D on Clonal Cytotoxic T Cells
  Viny AD, Clemente M, Jasek M, Prince C, Maciejewski JP, American Society of Hematology, 1/1/2008
• High Resolution Karyotyping of Large Granular Lymphocyte Leukemia by SNP Arrays Reveals Clonal Defects Leading to LOH at Loci Integral to Lymphocyte Function
  Viny AD, Makishima H, Huh J, Theil KS, Gondek L, Maciejewski JP, American Society of Hematology, 1/1/2008
• Statistical methodology using random forests for whole genome association studies in rare diseases
  Viny AD, Ishwaran H, Przychodzen B, Dunbar A, Maciejewski JP, Conference on Clinical Research on Rare Diseases, Bethesda, MD, 1/5/2007
• MICA Polymorphism Identified by Whole Genome Array Constitutes a Disease Predisposition Factor in T-Cell Large Granular Lymphocyte Leukemia
  Viny AD, Ishwaran H, Przychodzen, B, Dunbar A, Maciejewski JP, Blood, 1/1/2007
• Chronic B-cell Dyscrasias are and Important Clinical Feature of LGL Leukemia
  Viny AD, Lichtin, A., Pohlman, B., Nearman, Z., Loughran, T., Maciejewski, JP, Blood, 1/1/2007
• Non Synonymous SNP-Array-Based Disease Association Analysis in Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria
  Serio B, Viny AD, Tiu R, Przychodzen B, Lichtin A, O'Keefe C, Maciejewski JP, Blood, 1/1/2007
• Impact of Cytokine Polymorphisms in Aplastic Anemia
  Serio B, Risitano AM, Ramsingh G, Tiu R, Viny A, Rotoli B, Selleri C, Maciejewski JP, Italian Society of Hematology, Bologna, Italy, 1/1/2007
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Lectures

• Dose Dependency of the Cohesin Complex in Normal and Malignant Hematopoiesis 
  Orlando, FL - 1/8/2015
• Desmoplastic Small Round Cell Tumor: Analysis of 161 Cases at two Major Sarcoma Centers 
  Paris, France - 1/1/2014
• MICA polymorphism identified by whole genome array associated with NKG2D-mediated cytotoxicity in T-cell large granular lymphocyte leukemia 
  New York, NY - 1/8/2012
• T Cell Receptor Variable Beta Chain Analysis in the Diagnosis of Chronic Neutropenias 
  Iraklion, Crete - 1/1/2008
• Statistical methodology using random forests for whole genome association studies in rare diseases 
  Bethesda, MD - 1/5/2007
• Data Show Childhood, Youth Cancer Survival Factors Vary by Race, Follow-up Care 
  1/4/2007
• Analysis of large granular lymphocyte leukemia using high-density single nucleotide arrays 
  1/1/2007
• Disparities in Pediatric Cancers 
  Cleveland, OH - 1/12/2006
• The Racial Disparity Gap in Pediatric Leukemia and Lymphoma Survival Has Been Eliminated in Children But Not in Older Adolescents and Young Adults 
  1/1/2006
• Black-White Racial Disparity in the Survival of Young Adults with Cancer 
  1/1/2006
• High-Resolution Genomic Arrays Facilitate Detection of Novel Cryptic Chromosomal Lesions in MDS 
  1/1/2005
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Other

• Racial Disparity Persists in Survival Data 
  Viny, AD, RSi News
  http://www.rsinewsrxreportingfrom.com/content.asp?myid=62&tid=574
  1/12/2006
• Disparity Gap for Leukemia Patients 
  Viny, AD, National Public Radio
  http://audio2.ideastream.org/wcpn/2006/1211leukemia.mp3
  1/11/2006
• Childhood, Youth Cancer Survival Factors Vary by Race, Follow-Up Care 
  Viny, AD, American Society of Hematology Press Release
  http://www.hematology.org/media/therapy2_release.pdf
  1/11/2006
• Coming Full Circle: In Remission from ALL, Medical Student Focuses His Research on Cancer 
  Viny, AD and Maciejewski, JP, Cancer Consult Magazine
  1/1/2005
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