ThomasT.PerlsMD

PubMed

• Tailored Approach to Designing a Digital Research Platform for Adults Aged 95 and older: SuperAgers Family Study.
  Sofiya Milman, Aisha Montgomery, Nir Barzilai, Tina Gao, Kara A Wilson
  The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2025-02-05
• Causal mediation analysis of the neuroprotection ofthrough lipid pathways.
  Qingyan Xiang, Judith J Lok, Nicole Roth, Stacy L Andersen, Thomas T Perls
  Medrxiv. 2025-01-05
• SNP rs6543176 is associated with extreme human longevity but increased risk for cancer.
  Anastasia Gurinovich, Zeyuan Song, Harold Bae, Anastasia Leshchyk, Mengze Li
  Geroscience. 2025-01-03

Journal Articles

• Reduced Prevalence and Incidence of Cognitive Impairment Among Centenarian Offspring  
  Thomas Perls, MD, The Journals of Gerontology
• Genetics of Human Longevity from Incomplete Data: New Findings from the Long Life Family Study  
  Stephen Thielke, Thomas T Perls, Anne B Newman, The Journals of Gerontology
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  Sebastiani P, Bae H, Sun FX, Andersen SL, Daw EW, Malovini A, Kojima T, Hirose N, Schupf N, Puca A, Perls TT, Aging, 9/1/2013
• Apolipoprotein E and familial longevity  
  Schupf N, Barral S, Perls T, Newman A, Christensen K, Thyagarajan B, Province M, Rossi WK, Mayeux R, Neurobiol Aging, 4/1/2013
• Health span approximates life span amongst many supercentenarians: Compression of morbidity at the approximate limit of life span  
  Andersen S, Sebastiani P, Deworkis D, Feldman L, Perls T, J Gerontol Biol Sci, 1/1/2012
• Genetic Signatures of Exceptional Longevity  
  Sebastiani P, Solovieff N, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Perls TT, Plos One, 1/1/2012
• Whole Genome Sequences of a Male and Female Supercentenarian, ages greater than 114 years  
  Sebastiani P, Riva A, Montano M, Pham P, Torkamani A, Scherba E, Benson G, Milton JN, Baldwin CT, Andersen S, Schork N, Steinberg MH, Perls T, Frontiers in Genetics of Aging, 1/1/2012
• Human longevity and common variations in the LMNA gene: a meta-analysis  
  Conneely KN, Capell BC, Erdos MR, Sebastiani P, Solovieff N, Swift AJ, Baldwin CT, Budagov T, Barzilai N, Atzmon G, Puca AA, Perls TT, Geesaman BJ, Boehnke M, Collins FS, Aging Cell, 1/1/2012
• Within- and between-species study of extreme longevity--comments, commonalities, and goals  
  Michael Anson R, Willcox B, Austad S, Perls T, J Gerontol A Biol Sci Med Sci, 1/1/2012
• The Genetics of Extreme Longevity: Lessons from the New England Centenarian Study  
  Sebastiani P and Perls TT, Front. Gene, 1/1/2012
• 100 Semi-supercentenarians and older as a proposed sample set for the Archon Genomics X PRIZE Validation Protocol  
  Perls T, Barzilai, N, Nature Precedings, 1/1/2011
• Typologies of Extreme Longevity Myths  
  Young RD, Desjardins B, McLaughlin K, Poulain M, Perls T, Current Gerontology and Geriatrics Research, 1/1/2010
• Growth hormone and anabolic steroids: athletes are the tip of the iceberg  
  Perls T, Drug Testing and Analysis, 1/1/2009
• New developments in the illegal provision of growth hormone for "anti-aging" and bodybuilding  
  Olshansky SJ, Perls T, JAMA, 6/1/2008
• Guest editors' response  
  Hayflick L, Olshansky SJ, Perls TT, J Gerontol A Biol Sci Med Sci, 1/1/2005
• Introduction: Anti-Aging Medicine: The Hype and the Reality—Part II  
  Olshansky SJ, Hayflick L, Perls TT, J Gerontol Series A: Bio Sci Med Sci, 1/1/2004
• Antiaging quackery: Human growth hormone and tricks of the trade, more dangerous than ever  
  Perls, T, J Gerontol Biol Sci, 1/1/2004
• Exceptional Longevity: Winning the environmental-genetic lottery  
  Perls, T, Exp Med, 1/1/2004
• Measuring functional decline in population aging in a changing world and an evolving biology [Commentary on Robine and Michel's "Looking forward to a general theory on...  
  Mor V, Perls TT, J Gerontol Med Sci, 1/1/2004
• Cardiovascular disease delay in centenarian offspring  
  Terry DF, Wilcox MA, McCormick MA, Perls TT, J Gerontol Med Sci, 1/1/2004
• Cardiovascular Disease Delay in Centenarian Offspring: Role of Heat Shock Proteins  
  Terry D, McCormick M, Andersen S, Pennington J, Schoenhofen E, Palaima E, Mambula S, Bausero M, Gor D, Perls T, Asea A, Annals of the New York Acad Sci, 1/1/2004
• Reduced all-cause, cardiovascular and cancer mortality in centenarian offspring  
  Terry DF, Wilcox M, McCormick M, Pennington J, Schoenhofen E, Andersen S, Perls T, J Amer Geriatr Soc, 1/1/2004
• Introduction: Anti-Aging Medicine: The Hype and the Reality—Part I  
  Olshansky SJ, Hayflick L, Perls TT, J Gerontol Series A: Bio Sci Med Sci, 1/1/2004
• Centenarians who avoid dementia  
  Perls T, Trends in Neurosciences, 1/1/2004
• Haplotype based identification of a microsomal transfer protein marker associated with human lifespan  
  Geesaman BJ, Benson E, Brewster SJ, Kunkel LM, Blanché H, Thomas G, Perls TT, Daly MJ, Puca AA, Proc Natl Acad Sci USA, 1/1/2003
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