TheodoreLengMD, FACS

Ophthalmology • Stanford, CA

Cataract Related, Retinal Disease

Retina Specialist @ Byers Eye Institute at Stanford

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Office
300 Pasteur Dr
Stanford, CA 94305
Phone+1 650-723-4000

Fax+1 650-565-8297

Summary

Dr. Leng is considered to be one of the top 150 worldwide leading innovators in the field of medical and surgical retina and serves the Department of Ophthalmology as both the Director of Clinical and Translational Research and the Director of Ophthalmic Diagnostics.

He is a board-certified ophthalmologist and fellowship-trained vitreoretinal surgeon. Dr. Leng specifically focuses on surgery for macular holes, epiretinal membranes and macular pucker, and performs several of these types of surgery on a weekly basis. Dr. Leng uses the latest techniques and small-incisional sutureless technology to minimize patient discomfort and maximize functional outcomes.

Dr. Leng's medical retina specialties include the diagnosis and treatment of macular degeneration, diabetic retinopathy, diabetic macular edema and retinal vein occlusions. Dr. Leng is committed to bringing the highest level of patient-centered care for all types of retinal conditions.

Education & Training

Stanford Health Care-Sponsored Stanford UniversityFellowship, Surgical Retina and Vitreous, 2009 - 2010
University of Miami/Jackson Health System/Bascom Palmer Eye InstituteResidency, Ophthalmology, 2006 - 2009
Bascom Palmer Eye Institute2006 - 2009
Huntington Memorial HospitalInternship, Internal Medicine, 2005 - 2006
Stanford University School of MedicineDoctor, 2000 - 2005
Stanford University School of MedicineClass of 2005
Stanford UniversityAB/BS, Honors, 1995 - 1999

Certifications & Licensure

CA State Medical License 2009 - 2027
NM State Medical License 2023 - 2027
FL State Medical License 2012 - 2026
MI State Medical License 2023 - 2026
TX State Medical License 2015 - 2026
WA State Medical License 2016 - 2025
American Board of Ophthalmology Ophthalmology

Awards, Honors, & Recognition

America’s Top Ophthalmologists Consumer’s Research Council of America, 2012-2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
Fellow (FAAO) American Academy of Ophthalmology, 2011
Heed Ophthalmic Foundation Fellowship Heed Ophthalmic Foundation, 2010
Scholarship Annenberg Center for Health Sciences at Eisenhower Mentoring Program, 2009
Pan-American Ophthalmological Foundation Paul Kayser International Travel Scholar Pan-American Ophthalmological Foundation, 2009
Heed Ophthalmic Foundation Residents’ Retreat Heed Ophthalmic Foundation, 2008
Fellowship Stanford Medical Scientist Research Fellowship, 2003
NASA Certificate of Recognition for a Patent Filed with the USPTO NASA, 2003
NASA Certificate of Recognition for Creative Development of a Technical Innovation to be Published as a Technical Brief NASA, 2003
National Eye Institute ARVO Travel Award National Eye Institute, 2003
Research Training Fellowship for Medical Students Howard Hughes Medical Institute, 2003
Best Oral Presentation Stanford Medical Student Research Symposium, 2002
Kolos Scholar Stanford Medical Scholars Research Fellowship, 2001
Travel Award AMA National Convention, Chicago, IL, 2001
Baxter Foundation Scholar Stanford Medical Scholars Research Fellowship, 2001
Award for Excellence in Teaching Stanford Department of Biological Sciences, 2000
Firestone Medal for Excellence in Research Firestone Medal for Excellence in Research, awarded for Undergraduate Honors Thesis Standford University, 1999
Helen and Peter Bing Undergraduate Research Fellowship in Chemistry Helen and Peter Bing Foundation, 1998
Undergraduate Research Fellowship Stanford Center for Materials Research, 1997
Fellow (FACS) American College of Surgeons
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Clinical Trials

Endogenous Endophthalmitis in the Inpatient Setting Start of enrollment: 2010 Jul 01
Completed
Study of Bimonthly VEGF Trap-Eye Compared to As-needed Administration or Other Therapy for Exudative Age-Related Macular Degeneration Start of enrollment: 2012 Jan 01
Completed
Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Age-Related Macular Degeneration (AMD) Start of enrollment: 2012 Jun 01
Completed
Phase 1, Phase 2
Rates of Apnea in Patients Undergoing Vitreoretinal Surgery Start of enrollment: 2012 Aug 01
Completed
Outcomes of Diabetic Macula Edema Patients Switched to Aflibercept From Bevacizumab and/or Ranibizumab Start of enrollment: 2013 Sep 01
Completed
Study of HUCNS-SC Subretinal Transplantation in Subjects With GA of AMD Start of enrollment: 2015 Jun 01
Terminated
Phase 2
A Phase I Study of Episcleral Dexamethasone for Treatment of Macular Edema Start of enrollment: 2019 Apr 03
Active, not recruiting
Phase 1
Episcleral Dexamethasone for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole Start of enrollment: 2019 Sep 01
Active, not recruiting
Phase 1
Phase I Study of Episcleral Celecoxib for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole Start of enrollment: 2021 Mar 05
Active, not recruiting
Phase 1
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Publications & Presentations

PubMed

Distributed training of foundation models for ophthalmic diagnosis.
Sina Gholami, Fatema-E Jannat, Atalie Carina Thompson, Sally Shin Yee Ong, Jennifer I Lim
Communications Engineering. 2025-01-22
How intravitreal anti-vascular endothelial growth factor initial dosing impacts patient outcomes in diabetic macular oedema.
Rishi P Singh, David Tabano, Blanche L Kuo, Andrew LaPrise, Theodore Leng
BMC Ophthalmology. 2024-12-30
Functional Outcomes and Quality of Life in Geographic Atrophy in the Clinical Setting.
Durga Borkar, Ehsan Rahimy, Mohammed Ali Khan, Allen C Ho, Meghan Hatfield
Ophthalmology. Retina. 2024-11-20

Journal Articles

Progression of Photoreceptor Degeneration in Geographic Atrophy Secondary to Age-Related Macular Degeneration
Theodore Leng, Monika Fleckenstein, JAMA Ophthalmology
Behavioural difference of vascularized and non-vascularized retina after subretinal implantation of cellulose acetate membrane.
Molnar FE, Yellachich D, Leng T, Agurto R, Quiroz H, Dalal R, Huie P, Noolandi J, Blumenkranz MS, Marmor MF, Fishman HA, J Vision
Effect of povidone-iodine antisepsis applied prior to lidocaine gel anesthesia.
Leng T, Doshi RR, Fung AE, American Society of Retina Specialists Annual Meeting
Subretinal implant of polycarbonate membrane in pig model, tomographic and histological results at eleven weeks.
Agurto-Rivera R, Yellachich D, Quiróz-Mercado H, Alvarez-Rivera G, Blumenkranz MS, Molnar FE, Leng T, Dalal R, Marmor MF, Noolandi J, Invest. Ophthalmol. Vis. Sci.
Synthetic Bruch's Membrane substitutes: comparisons after subretinal transplantation with cultured iris pigment epithelium.
Molnar FE, Lombardi L, Berker N, Yeh E, Yellachich D, Leng T, Dalal R, Marmor MF, Fishman HA, Blumenkranz MS, Invest. Ophthalmol. Vis. Sci
Full thickness retinal pigment epithelium explants proliferate into epithelial monolayers on synthetic Bruch’s Membrane substitutes.
Lombardi L, Leng T, Yeh E, Molnar F, Noolandi J, Marmor MF, Fishman HA, Blumenkranz MS, Invest. Ophthalmol. Vis. Sci.
Local RPE cells migrate on the uneven surface of two potential Bruch's membrane substitutes after subretinal implantation: 3263.
Molnar FE, Yellachich D, Leng T, Huie P, Dalal R, Marmor MF, Fishman HA, Blumenkranz MS, Acta Ophthalmol. Scand
Spectral domain optical coherence tomography characteristics of vitelliform macular detachments in patients with basal laminar drusen.
Leng T, Punjabi O, Gregori G, Puliafito CA, Rosenfeld PJ, Invest. Ophthalmol. Vis. Sci.
Proteus species endophthalmitis: a 14-year review of the clinical spectrum, antibiotic sensitivities, and visual outcomes.
Leng T, Miller D, Flynn HW, Invest. Ophthalmol. Vis. Sci
Analysis of clear corneal incision (CCI) architecture with anterior segment spectral-domain OCT (AS-SDOCT).
Leng T, Wang J, Yoo SH, Lujan BJ, Tao A, Tsechpenakis G, ASCRS
Delayed-onset bleb-associated endophthalmitis: causative organisms, antibiotic sensitivities, and visual acuity outcomes (1996-2008).
Leng T, Miller D, Flynn HW, Gedde SJ, Invest. Ophthalmol. Vis. Sci.
Outcomes of delayed-onset bleb-associated endophthalmitis (1996-2008).
Leng T, Miller D, Flynn HW, Gedde SJ, 5th International Conference on Ocular Infections
Management of endophthalmitis while preserving the uninvolved crystalline lens.
Townsend JH, Leng T, Wykoff CC, Lingappan A, Miller D, Flynn HW, Invest. Ophthalmol. Vis. Sci.
Enhanced safety of retinal photocoagulation by spatial and temporal modulation of laser beam.
Sramek C, Brown J, Leung LB, Leng T, Palanker DV, Invest. Ophthalmol. Vis. Sci.
Retinal plasticity and restoration of function after photocoagulation.
Sher A, Leung LB, Leng T, Nomoto H, Paulus YM, Gariano RF, Jones BW, Litke AM, Palanker DV, Invest. Ophthalmol. Vis. Sci.
Restorative retinal photocoagulation.
Sher A, Leung LB, Leng T, Nomoto H, Paulus YM, Gariano RF, Jones BW, Litke AM, Palanker DV, Invest. Ophthalmol. Vis. Sci.
How are causative organisms associated with visual outcomes?
Jacobs DJ, Leng T, Miller D, Flynn HW, Gedde SJ, Invest. Ophthalmol. Vis. Sci.
Selective retinal therapy with microsecond exposures using a continuous line scanning laser.
Leng T, Paulus YM, Jain A, Nomto H, Sramek C, Gariano RF, Andersen D, Schuele G, Leung L, Blumenkranz MS, Palanker DV, Retina Society Annual Meeting
A retinal interface based on neurite micropatterning for single cell stimulation.
Mehenti NZ, Peterman MC, Leng T, Marmor MF, Blumenkranz MS, Bent SF, Fishman HA, Invest. Ophthalmol. Vis. Sci.
Capillary electrophoresis coupled with rat mast cells as a single-cell biosensor.
Leng T, Zare RN, 11th Annual ACS Undergraduate Research Conference
Directed ganglion cell growth and stimulation with microcontact printing as a prototype visual prosthesis interface.
Leng T, Blumenkranz MS, Fishman HA, 9th Annual Stanford Medical Student Research Symposium
Tissue-engineered neurite conduits to connect retinal ganglion cells to an electronic retinal prosthesis.
Huie P, Peterman MC, Leng T, Lee CJ, Marmor MF, Bloom DM, Blumenkranz MS, Fishman HA, Invest. Ophthalmol. Vis. Sci.
Tissue engineered lens capsule as a substrate for IPE and RPE transplantation.
Fung AE, Lee CJ, Leng T, Bilbao KV, Peterman MC, Blumenkranz MS, Bent SF, Fishman HA, Invest. Ophthalmol. Vis. Sci.
The artificial synapse chip: a novel interface for a retinal prosthesis based on neurotransmitter stimulation and nerve regeneration.
Fishman HA, Peterman MC, Leng T, Huie P, Lee CJ, Bloom DM, Sanislo SR, Marmor MF, Bent SF, Blumenkranz MS, Invest. Ophthalmol. Vis. Sci.
A biodegradable matrix facilitates the use of lens capsule as a substrate for subretinal cell transplantation.
Bilbao KV, Leng T, Fung AE, Huie P, Sanislo SR, Marmor MF, Blumenkranz MS, Fishman HA, Invest. Ophthalmol. Vis. Sci.
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Lectures

X-Linked retinoschisis.
Bascom Palmer Eye Institute Grand Round
Single-cell detectors for capillary electrophoresis.
51st Annual Pittsburgh Conference
Separating and detecting proteins with capillary electrophoresis and a living cell immunosensor.
2nd Annual Pittsburgh Conference
Retinal prosthetics as a treatment for macular degeneration.
The Future is Now: A Community Forum on 21st Century Medicine, Arrillaga Alumni Center, Stanford U
Analysis of clear corneal wound architecture with spectral domain optical coherence tomography.
44th Annual Residents’ Days, Bascom Palmer Eye Institute, Miami, FL
Hypotony maculopathy secondary to a cyclodialysis cleft.
Bascom Palmer Eye Institute Grand Rounds
Toxic epidermal necrolysis.
Bascom Palmer Eye Institute Grand Rounds
Retinal vascular tumor in systemic tuberculosis.
Bascom Palmer Eye Institute Grand Rounds
Necrotizing retinitis in Devic’s Syndrome.
Bascom Palmer Eye Institute Grand Rounds
he effects of anti-VEGF medications on the SDOCT characteristics of vitelliform macular detachments in patients with basal laminar drusen.
43rd Annual Residents’ Days, Bascom Palmer Eye Institute, Miami, FL
Neurosarcoidosis.
Bascom Palmer Eye Institute Grand Rounds
Age-related macular degeneration: pathogenesis and treatment.
Palo Alto Medical Foundation, Palo Alto, CA
Project Medishare mission to Thomonde, Haiti.
Bascom Palmer Eye Institute Grand Rounds
Orbital implant Taser injury.
Bascom Palmer Eye Institute Grand Rounds
Ophthalmology at Siriraj Hospital in Bangkok, Thailand.
Bascom Palmer Eye Institute Grand Rounds
Retinal vascular tumors.
Department of Ophthalmology Grand Rounds, Siriraj Hospital, Bangkok, Thailand
Delayed-onset bleb-associated endophthalmitis (1996-2008).
45th Annual Residents’ Days, Bascom Palmer Eye Institute, Miami, FL
Management of traumatic cyclodialysis clefts.
Stanford Ophthalmology Grand Rounds
Delayed-onset bleb-associated endophthalmitis: causative organisms and treatment outcomes.
46th Annual Residents’ Days, Bascom Palmer Eye Institute, Miami, FL
Intravitreal dexamethasone in the management of delayed-onset bleb-associated endophthalmitis.
47th Annual Residents’ Days, Bascom Palmer Eye Institute, Miami, FL
Quantitative analysis of retinal optical coherence tomography images in age- related macular degeneration.
5th Annual Stanford Ophthalmology Day, Stanford University, Stanford, CA
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Other

Eyelid and orbital implant injury after enucleation.
Leng T, www.ophthalmologyweb.com
http://www.tinyurl.com/
Glaucoma valves and shunts.
Leng T, http://tinyurl.com/bc82p8
http://www.ophthalmologyweb.com

Authored Content

Progression of Photoreceptor Degeneration in Geographic Atrophy Secondary to Age-Related Macular DegenerationAugust 2020
Progression of Photoreceptor Degeneration in Geographic Atrophy Secondary to Age-Related Macular DegenerationAugust 2020

Press Mentions

Solar Retinopathy: Eyes on an EclipseAugust 19th, 2024
Daily Supplements May Slow 'Dry' Form of Macular DegenerationJuly 29th, 2024
Assessing Treatment Patterns and Vision with Intravitreal Anti-VEGF in Patients with Neovascular AMDNovember 15th, 2021
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Committees

President, Stanford Medicine Alumni Association Board of Governors 2015 - Present
Member, American Society of Retina Specialists Fellowship Education and Training Committee 2015 - Present
Editorial Board Member, The Open Ophthalmology Journal 2014 - Present
Editorial Board Member, American Academy of Ophthalmology EyeWiki Retina/Vitreous Section Committee 2014 - Present
Editorial Board Member, American Society of Retina Specialists Retina Image Bank 2013 - Present
Editorial Board Member, Ophthalmic Surgery, Lasers, and Imaging Retina 2012 - Present
Member, Howard Hughes Medical Institute Bay Area Alumni Network Steering Committee 2012 - Present