Dr. Goldstein is on Doximity
As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.
- Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
- Connect with colleagues in the same hospital or clinic.
- Read the latest clinical news, personalized to your specialty.
Office
865 Health Sciences Quad
VCHA Suite 5th Fl
Irvine, CA 92617Phone+1 949-824-6426
Summary
- With over 30 years of experience as a physician-scientist, pediatric cardiologist, and academic administrator, my life’s work is focused on improving the human condition through the best in education, research and care. At the UCI, I am helping to bring this vision to fruition as the Vice Chancellor of Health Affairs, leading the development of the Susan and Henry Samueli College of Health Sciences (SCoHS) and UCI Health, our healthcare system. We are pursuing opportunities to improve the health and well-being of Californians while educating the diverse healthcare workforce of the future, endeavors made possible by our interprofessional college structure and the expansion of our clinical service sites.
My own work has spanned different systems and responsibilities in academic medicine and higher education. As a leader, I enlist aspirational problem-solvers and team players whose satisfaction derives from helping others succeed; I have found this inspires a spirit of openness and productivity that advances organizational achievement. A career overseeing world-class physicians, open-minded scientists, dedicated educators and selfless administrators has also taught me the importance of balancing guidance with a respect for freedom to operate, optimizing the benefits of assembling exceptional personnel, and the power of transparency, diversity and respect.
In addition to administrative endeavors, I have maintained a complementary career as a researcher and educator. My laboratory focuses on ion channels, essential proteins in each of our cells that produce heartbeats and other “excitable” membrane phenomena that are fundamental to health and treatment of disease. I am proud of the 60 research trainees who have worked with me and then gone on to exciting careers in academia, industry and service.
Education & Training
- Boston Children’s Hospital/Boston Medical CenterResidency, Pediatrics, 1987 - 1988
- Boston Children’s Hospital/Boston Medical CenterInternship, Pediatrics, 1986 - 1987
- Harvard Medical SchoolClass of 1986, MD
- Harvard UniversityPhD, Pathology (Immunology), 1986
- Brandeis UniversityMA, Biochemistry, 1978
- Brandeis UniversityBA, Biochemistry, Magna Cum Laude, 1978
- Boston Children’s Hospital/Boston Medical CenterFellowship, Pediatric Cardiology
Certifications & Licensure
- CT State Medical License Current
- MA State Medical License Current
- CA State Medical License 2020 - 2024
- IL State Medical License Active through 2023
- American Board of Pediatrics Pediatrics
Awards, Honors, & Recognition
- Fellow American Association for the Advancement of Science (AAAS), 2020
- Pritzker Scholar University of Chicago, 2004-2009
- E. Mead Johnson Award Society for Pediatric Research, 2001
- Join now to see all
Publications & Presentations
PubMed
- 29 citationsVoltage-sensor movements describe slow inactivation of voltage-gated sodium channels I: wild-type skeletal muscle Na(V)1.4.Jonathan R. Silva, Steve A.N. Goldstein
The Journal of General Physiology. 2013-03-01 - 97 citationsSUMO modification of cell surface Kv2.1 potassium channels regulates the activity of rat hippocampal neurons.Leigh D. Plant, Evan Dowdell, Irina Dementieva, Jeremy D. Marks, Steve A.N. Goldstein
The Journal of General Physiology. 2011-05-01 - 108 citationsSite-specific mutations in a minimal voltage-dependent K+ channel alter ion selectivity and open-channel block.Steve A.N. Goldstein, Christopher Miller
Neuron. 1991-09-01
Journal Articles
- Hypoxia produces pro-arrhythmic late sodium current in cardiac myocytes by SUMOylation of NaV1.5 channelsLeigh D. Plant, L.D., Xiong, D., Romero, J., Dai, H. and Steve A. N. Goldstein, Cell Reports, 2/18/2020
- Role of human Hv1 channels in sperm capacitation and white blood cell respiratory burst established by a designed peptide inhibitorZhao R, Kennedy K, De Blas GA, Orta G, Pavarotti MA, Arias RJ, de la Vega-Beltrán JL, Li Q, Dai H, Perozo E, Mayorga LS, Darszon A, and Goldstein SAN, Proc. Natl. Acad. Sci. (USA), 11/26/2018
- SUMOylation of NaV1.2 channels mediate the early response to acute hypoxia in central neuronsPlant, L.D., Marks, J.D. and S.A.N. Goldstein, eLife, 12/28/2016
- Join now to see all
Abstracts/Posters
- A common cardiac sodium channel variant associated with sudden infant death in African AmericansPlant, L.D., P.N. Bowers, Q. Liu, T. Morgan, T. Zhang, M.W. State, W. Chen, R.A. Kittles and S.A.N. Goldstein, J. Clin. Invest, 2006
- Sumoylation silences the plasma membrane leak K+ channel K2P1Rajan, S., L., Plant, M.L. Rabin, M.H. Butler, and S.A.N. Goldstein, Cell, 4/8/2005
- Forward Transport: 14-3-3 binding overcomes dibasic retention in endoplasmic reticulum by dibasic signalsO'Kelly, I., Butler, M.H., Zilberberg, N. and S.A.N. Goldstein, Cell, 11/15/2002
- Join now to see all
Authored Content
- Opinion: Academic health centers play unique role in battle against COVID-19 pandemicApril 2020
- A doctor’s demanding life here and in IraqJune 2004
Press Mentions
- Partnership to Unlock the Full Potential of Data to Advance the Science and Practice of Healthcare: Q&A with Syntropy and the University of California, IrvineOctober 11th, 2021
- U.S. On Track to Almost Triple Vaccine Output in March, as New Variants Pressure Europe and BrazilMarch 22nd, 2021
- UCI to Build World-Class Hospital on Irvine CampusJanuary 22nd, 2021
- Join now to see all
Committees
- Member, Association of American Medical Colleges, Medical Center Leaders Caucus 2019 - Present
- Member, Steering Committee, Association of American Medical Colleges, Group on Diversity and Inclusion 2018 - 2019
- Member, Association of American Medical Colleges, Liaison Committee on Medical Education Dean’s Group 2018 - 2019
- Member and Vice-Chair, National Science Foundation Biological Sciences Directorate Advisory Committee 2014 - 2017
- Scientific Advisor, National Institutes of Health, Roadmap in Nanomedicine 2005 - 2011
Professional Memberships
- Biophysical SocietyMember
- Society of General PhysiologistsMember
- Society Pediatric ResearchMember
- American Pediatric SocietyMember
- American College of Healthcare ExecutivesMember
External Links
- LinkedIn https://www.linkedin.com/in/steveangoldstein/
Viewing the full profile is available to verified healthcare professionals only.
Find your profile and take control of your online presence: