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Office
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon, NH 03756
Summary
- Dr. Ryan Little is a board-certified, fellowship-trained rhinologist with experience in the diagnosis, treatment, and management of problems involving the nose and sinuses. As a rhinologist practicing in an academic setting, Dr. Little is a resource to colleagues in otolaryngology - head & neck surgery offering comprehensive services for all aspects of medical and surgical treatment of primary and revision inflammatory sinusitis, anterior and central skull base neoplasms, orbital and optic nerve pathology, and otolaryngic allergy.
He attended medical school at the University of North Carolina School of Medicine in Chapel Hill, NC; and completed residency training in Otolaryngology—Head and Neck Surgery at the Medical College of Wisconsin's Froedtert Hospital and the Children's Hospital of Wisconsin in Milwaukee, WI.
Dr. Little subsequently pursued further subspecialty fellowship training in advanced rhinology, endoscopic sinus and skull base surgery at the Medical University of South Carolina in Charleston, SC under the mentorship of Rodney J. Schlosser, M.D. and Zachary M. Soler, M.D., MSc.
Clinical Expertise:
• All aspects of medical & surgical treatment of inflammatory sinusitis & revision sinus surgery
• Anterior & central skull base neoplasms
• Endoscopic repair of cerebrospinal fluid leaks & encephaloceles
• Nasal congestion & obstruction
• Orbital & optic nerve pathology (e.g. endoscopic two-wall orbital decompression for Graves' Thyroid Eye Disease)
• Otolaryngic allergy
• Smell & taste disorders
Clinical Expertise
- Juvenile nasopharyngeal angiofibroma, Chronic rhinitis, Cerebrospinal fluid leak, Olfactory neuroblastoma, Pituitary surgery, Endoscopic dacryocystorhinostomy, Rhinoplasty, Rhinology and paranasal sinus disease, Epistaxis, Septal perforation, Endoscopic frontal sinus surgery, Endoscopic sphenoid sinus surgery, Endoscopic ethmoid sinus surgery, Inverting papilloma of the nasal cavity or paranasal sinuses, Minimally invasive skull base surgery, Anterior skull base surgery, Vasomotor rhinitis, Nasal surgery, Nasal septum surgery, Empty nose syndrome, Endoscopic turbinate resection, Nasal cavity and paranasal sinus neoplasms, Endoscopic orbital decompresison
Education & Training
- University of New HampshirePeter T. Paul College of Business and Economics, New Hampshire Physician Leadership Development Program Business Administration and Management, General, 2022 - 2024
- Medical University of South CarolinaFellowship, Rhinology and Skull Base Surgery, 2019 - 2020
- Medical College of Wisconsin Affiliated HospitalsResidency, Otolaryngology - Head and Neck Surgery, 2014 - 2019
- University of North Carolina at Chapel Hill School of MedicineClass of 2014, MD
Awards, Honors, & Recognition
- Alpha Omega Alpha Honor Medical Society Alpha Omega Alpha (AOA), 2019
- North Carolina Board of Governors' Scholarship The University of North Carolina Board of Governors, 2010-2014
- Ezzard-Jones Scholarship University of North Carolina at Chapel Hill School of Medicine, 2012-2013
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Clinical Trials
- Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 2) Start of enrollment: 2022 May 13
- Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps Start of enrollment: 2022 Apr 22
- Impact of Highly Effective Modulator Therapy on the Cystic Fibrosis Microbiome Start of enrollment: 2023 Nov 08
Publications & Presentations
PubMed
- 78 citationsOdontogenic sinusitis: A review of the current literatureRyan E. Little, Christopher M. Long, Todd A. Loehrl, David M. Poetker
Laryngoscope Investigative Otolaryngology. 2018-03-25 - 11 citationsPharyngoesophageal diverticuli: diagnosis, incidence and managementRyan E. Little, Jonathan M. Bock
Current Opinion in Otolaryngology & Head and Neck Surgery. 2016-12-01 - 13 citationsEvaluating the Relationship Between Olfactory Function and Loneliness in Community-Dwelling Individuals: A Cross-sectional StudyVincent M. Desiato, Zachary M. Soler, Shaun A. Nguyen, Craig Salvador, Jonathan B. Hill
American Journal of Rhinology & Allergy. 2021-05-01
Authored Content
- Oral corticosteroid use and the risk of developing avascular necrosis: A large retrospective reviewJuly 2022
Press Mentions
- Sinus Center at Dartmouth Hitchcock Medical CenterOctober 9th, 2022
- Long Covid and smell: How to get the treatment you needOctober 15th, 2022
Grant Support
- Cystic Fibrosis Foundation Research Development Program (RDP)Cystic Fibrosis Foundation2024–2026
- Faculty Research AwardDartmouth Hitchcock Medical Center Department of Surgery2023–2024
- Biostatistical Consulting GrantNational Institutes of Health, National Center for Advancing Translational Sciences2017–2018
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Short Term Research Training GrantNational Institute of Health (NIH)2011–2012
Committees
- Committee Member, American Academy of Otolaryngology – Head & Neck Surgery. Allergy, Asthma, and Immunology Committee. 2022 - Present
- Committee Member, American Rhinologic Society. Patient Advocacy Committee. 2022 - Present
- Housestaff Representative, 1 year term elected position, Graduate Medical Education Committee Medical College of Wisconsin Affiliated Hospitals 2017 - 2018
- Froedtert & Medical College of Wisconsin Internal Occupational Health, Sharps Injury Prevention Team 2017 - 2018
- Medical College of Wisconsin Affiliated Hospitals, ACGME Clinical Learning Environment Review 2016 - 2016
- Otolaryngology Resident Alternate Representative, Medical College of Wisconsin Affiliated Hospitals Housestaff Health and Welfare Committee 2015 - 2016
Research History
- Medical University of South Carolina Mentors: Rodney J. Schlosser, MD; Zachary M. Soler, MD• Sleep quality in CRS • Age-related changes in olfactory cleft anatomy and airflow • Disease control in CRS • Lessons learned in silent sinus syndrome • Vitamin D metabolism in upper airway epithelial cells • Sub-investigator for multiple clinical trials2019 - 2020
- University of North Carolina School of Medicine Mentor: Adam M. Zanation, MDObjective: To review endoscopic endonasal transclival approaches according to clival region and the clinical outcomes for a diverse group of patients with benign and malignant lesions.2013 - 2014
- University of North Carolina School of Medicine Mentor: Jen Jen Yeh, MDObjective: To develop three-dimensional high-resolution ultrasound imaging protocols to accurately assess tumor volume and response to a novel surgically implanted drug delivery device in genetically engineered and patient-derived orthotopic mouse models of cancer (Patent PCT/US2010/025416).2011 - 2012
Professional Memberships
- Member
- Member
- American Rhinologic SocietyMember
External Links
- Ryan E Little, MD | Faculty Expertise Database – Geisel School of Medicine at Dartmouthhttps://geiselmed.dartmouth.edu/faculty/facultydb/view.php/?uid=7666
- Sinus Center | Dartmouth Hitchcock Medical Centerhttps://www.dartmouth-hitchcock.org/otolaryngology/sinus-center
- Ryan E Little, MD | Websitehttps://ryanlittlemd.com
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