RyanMichaelCarrMDPhD(He/Him)

Gastrointestinal Cancer

Assistant Professor of Medicine & Oncology

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I am a board certified medical oncologist specializing in treatment of patients with gastrointestinal malignancies with a focus on pancreatic cancer. I completed my training as a Clinical Investigator at Mayo Clinic in Rochester, MN. My research interests revolve around using the first principles of evolutionary ecology to better understand and treat pancreatic cancer. Thus, these interests range from the level of the cancer genome and epigenetic regulation, to the tumor microenvironment, and the development of adaptive therapies informed by evolutionary dynamics of tumors.

Mayo Clinic College of Medicine and Science (Rochester)Fellowship, Hematology and Medical Oncology, 2018 - 2021
Mayo Clinic College of Medicine and Science (Rochester)Residency, Internal Medicine, 2015 - 2018
University of Illinois College of MedicineClass of 2015
University of Illinois Champaign-UrbanaBS, Molecular and Cellular Biology, Summa Cum Laude, 2004 - 2008

ASCO Conquer Cancer Young Investigator Award Conquer Cancer Foundation, Alexandria, VA, 2022
Mayo Foundation Scholar Mayo Clinic, Rochester, MN, 2021
Top Performing Provider Award Mayo Clinic, Rochester, MN, 2020-2021
Cancer Center Eagles Fellowship Award Eagles 5th District, Rochester, MN, 2020
MSCO Outstanding Fellow Award Minnesota Society of Clinical Oncology, Rochester, MN, 2019-2020
ASH Abstract Achievement Award American Society of Hematology, Orlando, FL, 2019
Mangan Award for Excellence in Primary Care Mayo Clinic, Rochester, MN, 2017
Gold Humanism Honor Society University of Illinois, Chicago, IL, 2015
Edward P. Cohen Research Award University of Illinois, Chicago, IL, 2015
Craig Fellowship Research Award University of Illinois, Chicago, IL, 2010
Suma Cum Laude University of Illinois, Urbana-Champaign, IL, 2008
James Scholar University of Illinois, Urbana-Champaign, IL, 2008
Bronze Tablet Scholar University of Illinois, Urbana-Champaign, IL, 2008
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PubMed

46 citations
RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis
Ryan M. Carr, Denis Vorobyev, Terra L. Lasho, David L. Marks, Ezequiel J. Tolosa
Nature Communications. 2021-05-18
20 citations
Culture media composition influences patient-derived organoid ability to predict therapeutic responses in gastrointestinal cancers.
Tara L Hogenson, Hao Xie, William J Phillips, Merih D Toruner, Jenny J Li
JCI Insight. 2022-11-22
14 citations
Targeting of the Hedgehog/GLI and mTOR pathways in advanced pancreatic cancer, a phase 1 trial of Vismodegib and Sirolimus combination.
Ryan M. Carr, Narjust Duma, Angela L. McCleary-Wheeler, Luciana L. Almada, David L. Marks
Pancreatology. 2020-07-14

‘The Biggest Treasure Hunt You Can Imagine’: Inside the Digitization of Mayo Clinic’s Tissue Registry ArchiveAugust 19th, 2024
Experimental approach to treating pancreatic cancer heralded as a successJune 1st, 2022

Epigenetics of Pancreatic CancerElsa U. Pardee Foundation2023–2024
Use of Transcriptomic Signatures to Predict Personalized Gemcitabine Sensitivity in Pancreatic Cancer TreatmentASCO Conquer Cancer Foundation2022–2023