Robert O Heuckeroth MD M.D. Ph.D.
Pediatric Gastrointestinal Motility Disorders
Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
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3401 Civic Center BlvdChildrens Hospital of Philadelphia GastroenterologyPhiladelphia, PA 19104
Phone+1 215-590-3247
Fax+1 215-590-3606
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Education & Training
- Washington University/B-JH/SLCH ConsortiumResidency, Pediatrics, 1990 - 1992
- Washington University in St. Louis School of MedicineClass of 1990
Certifications & Licensure
- PA State Medical License 2013 - 2026
- MO State Medical License 1994 - 2014
- American Board of Pediatrics Pediatric Gastroenterology
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 2008
Publications & Presentations
PubMed
- Gene therapy ameliorates bowel dysmotility and enteric neuron degeneration and extends survival in lysosomal storage disorder mouse models.Ewa A Ziółkowska, Matthew J Jansen, Letitia L Williams, Sophie H Wang, Elizabeth M Eultgen
Science Translational Medicine. 2025-01-15 - Could Diverse Subtypes of Canonical and Schwann-like Enteric Glia Explain Diverse Glial Functions?Brian D Gulbransen, Robert O Heuckeroth
Gastroenterology. 2025-01-07 - Rapid cyclic stretching induces a synthetic, proinflammatory phenotype in cultured human intestinal smooth muscle, with the potential to alter signaling to adjacent bo...Sharon M Wolfson, Katherine Beigel, Sierra E Anderson, Brooke Deal, Molly Weiner
Biorxiv. 2024-10-15
Press Mentions
- HMN 2025: A Fatal Neurodegenerative Disease in Children Also Affects the BowelJanuary 16th, 2025
- CHOP, Washington University Researchers Reveal How Fatal Neurodegenerative Disease in Children Also Affects the BowelJanuary 16th, 2025
- Study Reveals Bowel Impact of Fatal Neurodegenerative Disease in ChildrenJanuary 15th, 2025
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Grant Support
- Mechanistic human studies to prevent Hirschsprung-associated enterocolitisCHILDREN'S HOSP OF PHILADELPHIA2025–2028
- Biochemical and cellular mechanisms linking actin mutations to visceral myopathyCHILDREN'S HOSP OF PHILADELPHIA2021–2026
- Biochemical and cellular mechanisms linking actin mutations to visceral myopathyCHILDREN'S HOSP OF PHILADELPHIA2021–2026
- Biochemical and cellular mechanisms linking actin mutations to visceral myopathyCHILDREN'S HOSP OF PHILADELPHIA2021–2026
- Biochemical and cellular mechanisms linking actin mutations to visceral myopathyCHILDREN'S HOSP OF PHILADELPHIA2021–2026
- Defining non-genetic mechanisms that prevent death in a Hirschsprung disease mouse modelCHILDREN'S HOSP OF PHILADELPHIA2021–2025
- Molecular and Functional Analysis of Hirschsprung Defects in Humans and MouseUNIVERSITY OF PITTSBURGH AT PITTSBURGH2020–2025
- Vitamin A Deficiency And Intestinal Motility DisordersNational Institute Of Diabetes And Digestive And Kidney Diseases2010–2012
- RET Ligand Regulation Of Intestinal MotilityNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2009
- Neuronal Control Of Intestinal Motility In Mutant MiceNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2007
- Proteomics Of Biliary AtresiaNational Institute Of Diabetes And Digestive And Kidney Diseases2004–2005
- Neurturin, A Novel Neurotrophic FactorEunice Kennedy Shriver National Institute Of Child Health &Human Development1997–2001
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