PatrickA.Zweidler-MckayMDMD/PhD

PubMed

• 204 citations
  Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group.
  Shalini C. Reshmi, Richard C. Harvey, Kathryn G. Roberts, Eileen Stonerock, Amy Smith
  Blood. 2017-06-22
• 240 citations
  The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal.
  H L Grimes, Tung O. Chan, P A Zweidler-Mckay, B Tong, Philip N. Tsichlis
  Molecular and Cellular Biology. 1996-11-01
• 514 citations
  Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia
  Rongqing Pan, Leah Hogdal, Juliana Benito, Donna Bucci, Lina Han
  Cancer Discovery. 2014-03-01

Abstracts/Posters

• A Phase I Study of IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate, in Patients with Relapsed/Refractory Acute Myeloid Leukemia, Blastic Plasmacytoid Dendriti...
  Patrick A. Zweidler-McKay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Clinical Profile of IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate (ADC), in Patients with Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) or Blastic ...
  Patrick A. Zweidler-McKay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Excellent Outcomes with Reduced Frequency of Vincristine and Dexamethasone Pulses in Children with National Cancer Institute (NCI) Standard-Risk B Acute Lymphoblastic ...
  Patrick A. Zweidler-McKay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Germline RUNX1 Variation and Predisposition to T-Cell Acute Lymphoblastic Leukemia in Children
  Patrick A. Zweidler-McKay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• The Genomic Landscape of Childhood Acute Lymphoblastic Leukemia
  Patrick A. Zweidler-McKay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• IMGN632, a CD123-Alkylating ADC Bearing a DNA-Alkylating IGN Payload, Combines Effectively with Azacitidine and Venetoclax In Vivo, Prolonging Survival in Preclinical ...
  Patrick A. Zweidler-McKay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• A Phase 1b/2 Study of the CD123-Targeting Antibody-Drug Conjugate IMGN632 As Monotherapy or in Combination with Venetoclax and/or Azacitidine for Patients with CD123-P...
  Patrick A. Zweidler-McKay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
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Lectures

• Triple Intrathecal Therapy (Methotrexate/Hydrocortisone/Cytarabine) Does Not Improve Disease-Free Survival Versus Intrathecal Methotrexate Alone in Children with High ... 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Maturing Clinical Profile of IMGN779, a Next-Generation CD33-Targeting Antibody-Drug Conjugate, in Patients with Relapsed or Refractory Acute Myeloid Leukemia 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• A Phase I, First-in-Human Study Evaluating the Safety and Preliminary Antileukemia Activity of IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate, in Patients wi... 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018