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Office
4500 San Pablo Rd S
Jacksonville, FL 32224Phone+1 904-953-2000
Summary
- Nilüfer Ertekin-Taner, MD, PhD is a Professor of Neurology and Professor of Neuroscience at the Mayo Clinic, Jacksonville, FL, USA. She is a neurogeneticist and board-certified behavioural neurologist. Dr. Ertekin-Taner received her medical degree from Hacettepe University Medical School in Ankara, Turkey and her doctorate degree in Molecular Neuroscience from Mayo Graduate School. She completed her residency training in the Department of Neurology at Mayo Clinic in Rochester, MN and fellowship in Behavioral Neurology at Mayo Clinic in Jacksonville, FL.
Dr. Ertekin-Taner’s laboratory aims to discover and characterize genetic factors underlying the complex genetics of Alzheimer’s disease (AD) and related neurodegenerative conditions. Her earlier work contributed to the establishment of the endophenotype approach in genetic studies of AD and pioneered the use of amyloid β peptide levels as an endophenotype in AD genetic research. Dr. Ertekin-Taner’s laboratory currently uses biological traits such as gene expression levels and cognitive scores and leverages combined genome, transcriptome and epigenetic data to uncover genetic risk factors for neurodegenerative conditions.
Dr. Ertekin-Taner is the Principal Investigator (PI) of numerous NIH and foundation grants. She leads multiple collaborative projects aimed at gene and pathway discoveries in AD and other neurodegenerative diseases, as part of the NIH initiatives Accelerating Medicines Partnership Alzheimer’s Disease (AMP-AD), Molecular Mechanisms of the Vascular Etiology of AD (M2OVE-AD) and Resilience-AD consortia. Dr. Ertekin-Taner is the PI of the Florida Consortium for African-American Alzheimer’s Disease Studies (FCA3DS). As a neurologist in the Memory Disorders Clinic at Mayo Clinic in Jacksonville, Florida, Dr. Ertekin-Taner continues to evaluate and manage patients with AD and other dementias and aspires to improve the quality of care that we provide to our patients and their families.
Education & Training
- Mayo Clinic College of Medicine and Science (Rochester)Residency, Neurology, 2004 - 2007
- Mayo Clinic College of Medicine and Science (Rochester)Internship, Internal Medicine, 2003 - 2004
- Mayo Clinic College of MedicinePost-Doctoral Fellowship, 2001 - 2003
- Mayo Graduate School, Mayo Clinic College of MedicinePhD, Molecular Neuroscience, 1997 - 2001
- Hacettepe University FOMClass of 1995
Certifications & Licensure
- FL State Medical License 2007 - 2025
- MN State Medical License 2005 - 2025
- American Board of Psychiatry and Neurology Neurology
- United Council for Neurologic Subspecialties (UCNS)Behavioral Neurology & Neuropsychiatry
Awards, Honors, & Recognition
- Investigator of the Year Mayo Clinic Florida, 2018
- FAAN American Academy of Neurology, 2017
- Health Care Hero Jacksonville Business Journal, 2008
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Publications & Presentations
PubMed
- 9 citationsEpigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer's disease risk in humans.Yiyi Ma, Lei Yu, Marta Olah, Rebecca Smith, Stephanie R Oatman
Alzheimer's & Dementia. 2022-04-01 - 8 citationsEffects of sex and APOE on Parkinson's Disease-related cognitive declinePhilip W. Tipton, Nazli G. Bulbul, Julia E. Crook, Zachary S. Quicksall, Owen A. Ross
Neurologia i Neurochirurgia Polska. 2021-10-13 - 24 citationsApolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids.Jing Zhao, Wenyan Lu, Yingxue Ren, Yuan Fu, Yuka A. Martens
Acta Neuropathologica. 2021-08-28
Press Mentions
- Mayo Researchers, Collaborators Identify ‘Instigator’ Gene Associated with Alzheimer’s DiseaseApril 19th, 2021
- Alzheimer's Disease Alters Oligodendrocytic Glycolytic and Ketolytic Gene ExpressionMarch 2nd, 2021
- Differential Transcript Usage Unravels Gene Expression Alterations in Alzheimer’s Disease Human BrainsJanuary 4th, 2021
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Grant Support
- INTEGRATIVE TRANSLATIONAL DISCOVERY OF VASCULAR RISK FACTORS IN AGING AND DEMENTIANational Institute on Aging2015–2020
- Florida Consortium for African-American Alzheimer’s Disease Studies (FCA3DS)Florida Health Ed and Ethel Moore Alzheimer's Disease Research Program2017–2019
- A Systems Approach to Targeting Innate Immunity in ADNational Institute on Aging2013–2018
- Gene discovery in PSP by transcriptome, neuropathology and sequence analysisNational Institute of Neurological Disorders and Stroke2013–2018
- Target pathway discovery in AD using transcriptomicsBrightFocus Foundation2013–2016
- Florida Consortium for African-American Alzheimer’s Disease Studies (FCA3DS)Florida Department of Health, Ed and Ethel Moore Alzheimer's Disease Research Program2015
- Mayo Clinic ADRC - Project 3National Institute on Aging2009–2014
- Genome wide association study of gene expression levels in Alzheimer's diseaseNational Institute on Aging2009–2013
- Clinical Research Scholars Program (CRSP)K12National Institutes of Health2008–2011
- AFAR Research Grant Program for Postdoctoral FellowsAmerican Federation for Aging Research2001–2003
Committees
- Scientific Reviewer, National Alzheimer's Coordinating Center 2015 - Present
Research History
- Research FellowshipDepartment of Neuroscience, Mayo Clinic College of Medicine2001 - 2003
Professional Memberships
- Member
Other Languages
- Turkish
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