NelsonLeungMD

PubMed

• 1298 citations
  The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms.
  Rita Alaggio, Catalina Amador, Ioannis Anagnostopoulos, Ayoma D Attygalle, Iguaracyra Barreto de Oliveira Araujo
  Leukemia. 2022-07-01
• 137 citations
  Systemic amyloidosis from A (AA) to T (ATTR): a review.
  Eli Muchtar, Angela Dispenzieri, Hila Magen, Martha Grogan, Michelle L. Mauermann
  Journal of Internal Medicine. 2021-03-01
• 60 citations
  Mutations in specific structural regions of immunoglobulin light chains are associated with free light chain levels in patients with AL amyloidosis.
  Tanya L. Poshusta, Laura A. Sikkink, Nelson Leung, Raynell J. Clark, Angela Dispenzieri
  Plos One. 2009-04-13

Journal Articles

• Monoclonal gammopathy of renal signficance  
  Leung, Bridoux and Nasr, New England Journal of Medicine, 5/20/2021
• Impact of Prior Diagnosis of Monoclonal Gammopathy on Outcomes in Newly Diagnosed Multiple Myeloma  
  S Vincent Rajkumar, Yi L Hwa, Wilson I Gonsalves, Francis K Buadi, Angela Dispenzieri, Prashant Kapoor, Miriam A Hobbs, Martha Q Lacy, John A Lust, Robert A Kyle, Mori..., Nature
• Safety and Efficacy of Propylene Glycol-Free Melphalan as Conditioning in Patients with AL Amyloidosis Undergoing Stem Cell Transplantation  
  Nelson Leung, Prashant Kapoor, Taxiarchis V Kourelis, Eli Muchtar, Angela Dispenzieri, M Hasib Sidiqi, Martha Q Lacy, Wilson I Gonsalves, Shaji K Kumar, Mohammed A Alj..., Nature
• Relapse After Complete Response in Newly Diagnosed Multiple Myeloma: Implications of Duration of Response and Patterns of Relapse  
  Angela Dispenzieri, Francis K Buadi, Morie A Gertz, Martha Q Lacy, Nelson Leung, Amie L Fonder, Wilson I Gonsalves, Yi Lisa Hwa, Taxiarchis Kourelis, Surbhi Sidana, Ro..., Nature
• Daratumumab-Based Therapy in Patients with Heavily-Pretreated AL Amyloidosis  
  Saurabh Zanwar, Angela Dispenzieri, Wilson Gonsalves, David Dingli, Jithma P Abeykoon, Martha Q Lacy, Shaji Kumar, Nelson Leung, Morie A Gertz, Eli Muchtar, Francis Bu..., Nature
• Optimizing Deep Response Assessment for AL Amyloidosis Using Involved Free Light Chain Level at End of Therapy: Failure of the Serum Free Light Chain Ratio  
  Morie A Gertz, David Dingli, Miriam Hobbs, John A Lust, Ronald S Go, Amie Fonder, Yi Lin, Shaji K Kumar, Prashant Kapoor, Taxiarchis V Kourelis, S Vincent Rajkumar, Ro..., Nature
• Utilization of Hematopoietic Stem Cell Transplantation for the Treatment of Multiple Myeloma: A Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consen...  
  John A Lust, Shaji K Kumar, Morie A Gertz, P Leif Bergsagel, Angela Dispenzieri, Francis K Buadi, Prashant Kapoor, Angela A Mayo, Wilson I Gonsalves, Rafael Fonseca, R..., Nature
• Congophilic Fibrillary Glomerulonephritis: A Case Series  
  Stephen B Erickson, Fernando C Fervenza, Nelson Leung, American Journal of Kidney Diseases
• Monoclonal Gammopathy of Clinical Significance: A Novel Concept with Therapeutic Implications  
  Robert A Kyle, Nelson Leung, Angela Dispenzieri, Blood
• Cisplatin Nephrotoxicity: A Review of the Literature  
  Nelson Leung, Sandhya Manohar, Journal of Nephrology
• Myeloma-related Kidney Disease  
  Leung N and Nasr SH, Adv Chronic Kidney Dis, 1/1/2014
• Long-term disease control in patients with newly diagnosed multiple myeloma after suspension of lenalidomide therapy  
  Kourelis TV, Kumar SK, Srivastava G, Gertz MA, Lacy MQ, Buadi FK, Hayman SR, Zeldenrust SR, Leung N, Kyle RA, Am J Hematol, 1/1/2014
• Proliferative Glomerulonephritis Due to Monoclonal Deposition With Organized Substructures  
  Hamadah AM, Keddis MT, Cornell LD, Leung N, Am J Kidney Dis, 1/1/2014
• Use of Bortezomib in Heavy-Chain Deposition Disease: A Report of 3 Cases  
  Patel K, Dillon JJ, Leung N, Bomback AS, Appel GB, D'Agati V, Canetta PA, Am J Kidney Dis, 1/1/2014
• Outcomes and treatments of patients with immunoglobulin light chain amyloidosis who progress or relapse postautologous stem cell transplant  
  Warsame R, Bang SM, Kumar SK, Gertz MA, Lacy MQ, Buadi F, Dingli D, Hayman SR, Kapoor P, Kyle RA, Leung N, Lust JA, Russell SJ, Witzig TE, Zeldenrust SR, Rajkumar SV,..., Eur J of Haematol, 1/1/2014
• Crystalglobulin-Induced Nephropathy  
  Gupta V, El Ters M, Kashani K, Leung N, Nasr SH, J Am Soc Neph, 1/1/2014
• Characterization and outcomes of renal leukocyte chemotactic factor 2-associated amyloidosis  
  Said SM, Sethi S, Valeri AM, Chang A, Nast CC, Krahl L, Molloy P, Barry M, Fidler ME, Cornell LD, Leung N, Vrana JA, Theis JD, Dogan A, Nasr SH, Kidney Int, 1/1/2014
• The use of immunoglobulin light chain assays in the diagnosis of paraprotein-related kidney disease  
  Yadav P, Leung N, Sanders PW, Cockwell P, Kidney Int, 1/1/2014
• Treatment of Persistent/Medically Refractory Covert Hepatic Encephalopathy With the Molecular Adsorbent Recirculating System  
  Leise MD, Leung N, El-Zoghby Z, Gonzalez, HCG, Cerhan JH, Nyberg SL, Liver Transplant, 1/1/2014
• Remission of Disseminated Cancer After Systemic Oncolytic Virotherapy  
  Russell SJ, Federspiel MJ, Peng KW, Tong CL, Dingli D, Morice WG, Lowe V, O'Connor MK, Kyle RA, Leung N, Buadi FK, Rajkumar SV, Gertz MA, Lacy MQ, Dispenzieri A, Mayo Clin Proc, 1/1/2014
• A pilot study to determine the dose and effectiveness of adrenocorticotrophic hormone (HP ActharA (R) Gel) in nephrotic syndrome due to idiopathic membranous nephropathy  
  Hladunewich MA, Cattran D, Beck LH, Odutayo A, Sethi S, Ayalon R, Leung N, Reich H, Fervenza, FC, Nephrol Dial Transplant, 1/1/2014
• Impact of Molecular Adsorbent Recirculating System Therapy on Tacrolimus Elimination: A Case Report  
  Personett HA, Larson SL, Frazee EN, Nyberg SL, Leung N, El-Zoghby AM, Transplant Proc, 1/1/2014
• Systemic amyloidosis associated with chronic lymphocytic leukemia/small lymphocytic lymphoma  
  Kourelis TV, Gertz M, Zent C, Lacy M, Kyle R, Kapoor P, Zeldenrust S, Buadi F, Witzig T, Hayman S, Lust J, Russell S, Lin Y, Rajkuma, VS, Kumar S, Leung, N, Dingli D, ..., Am J Hematol, 1/1/2013
• C3 Glomerulonephritis Associated With Monoclonal Gammopathy: A Case Series  
  Zand L, Kattah A, Fervenza FC, Smith RJ, Nasr SH, Zhang Y, Vrana JA, Leung N, Cornell LD, Sethi S, Am J Kidney Dis, 1/1/2013
• Refinement in patient selection to reduce treatment-related mortality from autologous stem cell transplantation in amyloidosis  
  Gertz MA, Lacy MQ, Dispenzieri A, Kumar SK, Dingli D, Leung N, Hogan WJ, Buadi FK, Hayman SR, Bone Marrow Transplant, 1/1/2013
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Books/Book Chapters

• Core concepts in parenchymal kidney disease. 
  Chapter: Monoclonal immunoglobulin deposition disease. 
  Page 291 - 300Kattah AG, Leung NEditors: Fervenza FC; et al.Springer, New York, NY2014
• Core concepts in parenchymal kidney disease. 
  Chapter: Amyloidosis. 
  Page 301 - 314Leung NEditors: Fervenza FC; et al.Springer, New York, NY2014
• Harrison's principles of internal medicine. 
  Chapter: Vascular injury to the kidney. 
  Page 2375 - 2382Textor SC and Leung NEditors: Longo DL; et al.McGraw-Hill Medical, New York, NYEdition 18th,2012
• Amyloidosis: Diagnosis and Treatment 
  Chapter: Supportive Care for Amyloidosis. 
  Page 65 - 76Lacy MQ and Leung NEditors: Eds Gertz MA and Rajkumar SV.Springer, New York, NYEdition 1st,2010
• Multiple Myeloma and Related Plasma Cell Disorders. 
  Chapter: Light Chain Deposition Disease. 
  Page 197 - 203Zeldenrust SR, Lager DJ, Leung NEditors: Gertz MA and Greipp PR.Springer-Verlag, Berlin2003
• Kelley’s Textbook of Internal Medicine 
  Chapter: Approach to Patient with Urinary Retention and Obstruction. 
  Page 1112 - 1119Leung N, Ghosh AK, Nath KAEditors: Humes HD.Lippincott Williams & Wilkins, Philadelphia, PAEdition 4th,
• Kelley’s Textbook of Internal Medicine 
  Chapter: Obstructive Uropathy. 
  Page 1238 - 1243Leung N, Ghosh AK, Nath KAEditors: Humes HD.Lippincott Williams & Wilkins, Philadelphia, PAEdition 4th,
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Abstracts/Posters

• Impact of Acute Kidney Injury Following Diagnosis of Aggressive Lymphoma or Acute Leukemia on Long-Term Kidney Outcomes
  Nelson Leung, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• A Novel Approach to Risk Stratification in Multiple Myeloma Using ISS Stage and FISH
  Nelson Leung, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Utilizing Multiparametric Flow Cytometry to Identify Patients with Primary Plasma Cell Leukemia at Diagnosis
  Nelson Leung, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Prognostic Implications of Serum Monoclonal Protein Positivity By Mass-Fix in Bone Marrow Minimal Residual Disease Negative (MRD-) Patients with Multiple Myeloma
  Nelson Leung, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Optimal Therapy for Relapsed AL Amyloidosis Post Autologous Stem Cell Transplant
  Nelson Leung, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• The Impact of Socioeconomic Risk Factors on the Survival Outcomes of Patients with Newly Diagnosed Multiple Myeloma
  Nelson Leung, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Phase 2 Trial of Daratumumab, Ixazomib, Lenalidomide and Modified Dose Dexamethasone in Patients with Newly Diagnosed Multiple Myeloma
  Nelson Leung, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• A Prospective Pilot Study of Ixazomib, Lenalidomide, and Dexamethasone for Patients with Newly Diagnosed or Relapsed/Refractory POEMS Syndrome
  Nelson Leung, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Metaphase Cytogenetics for Risk Stratification in Newly Diagnosed Multiple Myeloma
  Nelson Leung, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Impact of sFLC Ratio on Outcome in Patients with MM: Validating the Utility of sFLC in Response Definition
  Nelson Leung, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Mortality of Patients with Multiple Myeloma after the Introduction of Novel Therapies in the United States
  Nelson Leung, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Impact of Preemptive Leucovorin Dose Escalation on Incidence of Delayed Methotrexate Elimination in Lymphoma Patients Receiving High-Dose Methotrexate
  Nelson Leung, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• De novo multiple myeloma after kidney transplantation. (Poster)
  Safadi S, Leung N, Cosio F, Amer H, Gertz M, Rajkumar V, Hayman S, Lacy M, Dispenzieri A, National Kidney Foundation Spring Clinical Meetings, Las Vegas, NV, 4/22/2014
• Recurrent light chain proximal tubulopathy after renal and autologous stem cell transplantation. (Poster)
  Sathick IJ, Fidler ME, Lacy MQ, Leung N, National Kidney Foundation Spring Clinical Meetings, Las Vegas, NV, 4/22/2014
• The Prevalence of Circulating Monoclonal Protein in Proliferative Nephropathy with Monoclonal Deposits. (Plenary)
  Bhutani G, Fervenza FC, Sethi S, Nasr SH, Leung N, American Society of Nephrology Kidney Week, Atlanta, GA, 11/7/2013
• Granulomatous Interstitial Nephritis Secondary to Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma. (Poster)
  Nasr SH, Shanafelt T, Hanson C, Sethi S, Cornell LD, Fidler ME, Leung N, American Society of Nephrology Kidney Week, Atlanta, GA, 11/7/2013
• Redefining engraftment syndrome: the new Mayo Clinic criteria. (Poster)
  Burnette BL, Gertz M, Kumar S, Lacy M, Buadi F, Hayman S, Dingli D, Inwards DJ, Johnston PB, Micallef IN, Porrata LE, Hogan W, Litzow MR, Patnaik M, Hashmi S, Leung N,..., BMT Tandem Meetings, Salt Lake City, UT, 2/13/2013
• Refinement in Patient Selection to Reduce Treatment-Related Mortality From Stem Cell Transplantation in Amyloidosis. (Plenary)
  Gertz MA, Lacy MQ, Dispenzieri A, Kumar SK, Dingli D, Leung N, Hogan WJ, Buadi FK, Hayman SR, 54rd ASH Annual Meeting and Exposition, Atlanta, GA, 12/8/2012
• Outcomes of Patients with POEMS Syndrome Treated Initially with Radiation. (Plenary)
  Humeniuk M, Gertz MA, Lacy MQ, Kyle RA, Hayman SR, Kumar SK, Lust JA, Witzig TE, Buadi FK, Rajkumar SV, Zeldenrust SR, Russell SJ, Dingli D, Lin Y, Kapoor P, Leung N, ..., 54rd ASH Annual Meeting and Exposition, Atlanta, GA, 12/8/2012
• Renal Heavy Chain and Heavy+Light Chain Amyloidosis: A Report of 17 Cases and Comparison with Renal Light Chain Amyloidosis. (Poster)
  Nasr SH, Said SM, Valeri AM, Sethi S, Cornell LD, Fidler ME, Gertz MA, Dispenzieri A, Buadi FK, Vrana JA, Theis JD, Dogan A, Leung N, 54rd ASH Annual Meeting and Exposition, Atlanta, GA, 12/8/2012
• Survival After Second, Third, and Fourth Line Therapy Better Than Expected in Patients with Previously Treated AL Amyloidosis Who Were Not Transplant Candidates At Di...
  Raval, GG, Gertz MA, Lacy MQ, Hayman SR, Kumar SK, Buadi FK, Lust JA, Zeldenrust SR, Dingli D, Hall RL, Hwa L, Lin Y, Kapoor P, Witzig TE, Kyle RA, Russell S, Leung N,..., 54rd ASH Annual Meeting and Exposition, Atlanta, GA, 12/8/2012
• Outcomes and Treatments of Relapsed AL Amyloidosis Following Stem Cell Transplant. (Poster)
  Warsame R, Bang SM, Kumar SK, Lacy MQ, Buadi FK, Dingli D, Hayman DR, Lust JA, Russell S, Witzig TE, Kyle RA, Leung N, Zeldenrust SR, Rajkumar SV Gertz MA, Dispenzieri A, 54rd ASH Annual Meeting and Exposition, Atlanta, GA, 12/8/2012
• Acute Interstitial Nephritis: A Current Perspective. (Poster)
  Muriithi AK, Leung N, Cornell LD, Fidler ME, Sethi S, Nasr SH, American Society of Nephrology Kidney Week, San Diego, CA, 10/20/2012
• Do Urine Eosinophils Have a Role in the Diagnosis of Acute Interstitial Nephritis? (Poster)
  Muriithi AK, Nasr SH, Leung N, American Society of Nephrology Kidney Week, San Diego, CA, 10/20/2012
• Bortezomib for Heavy Chain Deposition Disease: A Report of Three Cases. (Poster)
  Patel K, Dillon JJ, Leung N, Bomback AS, Appel GB, Canetta PA, American Society of Nephrology Kidney Week, San Diego, CA, 10/20/2012
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Lectures

• Dysproteinemic Renal Disease 
  American Society of Nephrology Kidney Week 2019 - Washington, D.C. - 11/8/2019
• Disease Specific Management I, Lecturer 
  Mayo Clinic, Rochester, MN - 1/1/2015
• Monoclonal Gammopathy: are there still believers in the MGUS story? 
  10/19/2014
• Multiple Myeloma Related Renal Impairment in 2014: Treatment Strategies That Optimize Outcomes; An Update on Monoclonal Gammopathy Related Kidney Diseases 
  6/26/2014
• Monoclonal Gammopathies 
  Las Vegas, NV - 4/22/2014
• Nefropatias glomerulares por depósitos organizados de Inmunoglobulinas. 
  Barcelona, Spain - 4/7/2014
• Monoclonal gammopathies of renal significance. 
  Brugge, Belgium - 3/21/2014
• Hepatorenal Syndrome 
  1/2/2014
• Therapeutic Apheresis in Multiple Myeloma: Yea 
  Atlanta, GA - 11/8/2013
• Dysproteinemias 
  Atlanta, GA - 11/6/2013
• Update on dysproteinemia. 
  Minneapolis, MN - 9/20/2013
• Monoclonal Gammopathy and Kidney Disease. 
  6/28/2013
• Kidney Disease and Multiple Myeloma (and MGRS). 
  Toronto, Canada - 6/7/2013
• Spectrum of Light Chain-related Disorders 
  Hong Kong, China - 6/1/2013
• Chemotherapy of Light Chain-related Disorders 
  Hong Kong, China - 6/1/2013
• Monoclonal Gammopathies and Glomerular Diseases 
  Cagliari, Italy - 5/1/2013
• Dialysis and Transplantation for Multiple Myeloma Patients 
  Gramado, Brazil - 4/13/2013
• Renal Amyloidosis 
  Gramado, Brazil - 4/12/2013
• How to monoclonal gammopathy suspect and diagnosis-related nephropathy. 
  Gramado, Brazil - 4/12/2013
• Monoclonal Gammopathy of Renal Significance 
  Gramado, Brazil - 4/11/2013
• Nephrotoxicity of Monoclonal Light Chains 
  Kyoto, Japan - 4/6/2013
• Emerging Role of Monoclonal Gammopathy in the Pathogenesis of Kidney Disease 
  Lyon, France - 11/26/2012
• Emerging role of monoclonal gammopathy in the pathogenesis of kidney disease. 
  Casablanca, Morocco - 11/14/2012
• A Case of Nephrotic Syndrome and Renal Failure in an Older Adult with a Monoclonal Gammopathy of Undetermined Significance on Serum Protein Electrophoresis. 
  10/30/2012
• Treatment with Bortezomib in Multiple Myeloma with Renal Insufficiency 
  Montevideo, Uroguay - 9/29/2012
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Other

• Pathogenesis and diagnosis of myeloma cast nephropathy (myeloma kidney). 
  Appel G, Leung N, Rajkumar SV, UpToDate
  1/1/2015
• Renal Amyloidosis. 
  Leung N, Appel G, Kyle RA, UpToDate
  1/1/2015
• Types of Renal Disease in Multiple Myeloma. 
  Leung N, Appel G, Rajkumar SV, UpToDate
  1/1/2015
• Treatment of Kidney disease in multiple myeloma. 
  Rajkumar SV, Kaplan A, Leung N, UpToDate
  1/1/2015
• Myeloma Kidney (Nephrology & Hypertension Topic) 
  Leung N, AskMayoExpert
  1/1/2009
• Renal Amyloidosis (Nephrology & Hypertension Topic) 
  Leung N, AskMayoExpert
  1/1/2009
• Pathogenesis and diagnosis of myeloma cast nephropathy (myeloma kidney) 
  Leung N, Appel GB, Kyle RA
  http://www.uptodate.com/contents/pathogenesis-and-diagnosis-of-myeloma-cast-nephropathy-myeloma-kidn
  UpToDate, Wolters Kluwer Health - 2013-01-23
• Treatment of kidney disease in multiple myeloma 
  Leung N, Kaplan AA, Rajkumar SV
  http://www.uptodate.com/contents/treatment-of-kidney-disease-in-multiple-myeloma
  UpToDate, Wolters Kluwer Health - 2012-12-19
• Types of renal disease in multiple myeloma 
  Leung N, Appel GB, Kyle RA
  http://www.uptodate.com/contents/types-of-renal-disease-in-multiple-myeloma
  UpToDate, Wolters Kluwer Health - 2012-07-30
• Renal amyloidosis 
  Leung N, Appel GB, Kyle RA
  http://www.uptodate.com/contents/renal-amyloidosis
  UpToDate, Wolters Kluwer Health - 2012-09-10
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