Raja KannanMutharasanMD

PubMed

• 92 citations
  The Sulfonylurea Receptor, an Atypical ATP-Binding Cassette Protein, and Its Regulation of the KATP Channel
  Michael A. Burke, R. Kannan Mutharasan, Hossein Ardehali
  Circulation Research. 2008-02-01
• 114 citations
  Disruption of ATP-binding cassette B8 in mice leads to cardiomyopathy through a decrease in mitochondrial iron export
  Yoshihiko Ichikawa, Marina Bayeva, Mohsen Ghanefar, Vishnu Potini, Lin Sun
  Proceedings of the National Academy of Sciences of the United States of America. 2012-03-13
• 586 citations
  Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation
  Yoshihiko Ichikawa, Mohsen Ghanefar, Marina Bayeva, Rongxue Wu, Arineh Khechaduri
  The Journal of Clinical Investigation. 2014-02-03

Journal Articles

• HDL Efflux Capacity, HDL Particle Size and High-Risk Carotid Atherosclerosis in a Cohort of Asymptomatic Older Adults: The Chicago Healthy Aging Study  
  Mutharasan RK, Thaxton CS, Berry J, Daviglus ML, Yuan C, Sun J, Ayers C, Lloyd-Jones DM, Wilkins JT, J Lipid Res, 1/1/2017
• High-Density Lipoproteins for Therapeutic Delivery Systems  
  Mutharasan RK, Foit L, Thaxton CS, J. Mater. Chem. B Mater Biol Med., 1/14/2016
• Nanoparticle Targeting and Cholesterol Flux Through Scavenger Receptor Type B-1 Inhibits Cellular Exosome Uptake  
  Plebanek MP, Mutharasan RK, Volpert O, Matov A, Gatlin JC, Thaxton CS, Sci. Rep., 1/1/2015
• Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation  
  Ichikawa Y, Ghanefar M, Bayeva M, Wu R, Khechaduri A, Naga Prasad SV, Mutharasan RK, Naik TJ, Ardehali H, J Clin Invest, 1/1/2014
• MicroRNA-210 Decreases Heme Levels by Targeting Ferrocheletase in Cardiomyocytes  
  Qiao A, Khechaduri A, Mutharasan RK, Wu R, Nagpal V, Ardehali H, Qiao A, Khechaduri A, Mutharasan RK, Wu R, Nagpal V, Ardehali H, 1/22/2013
• Templated High Density Lipoprotein Nanoparticles as Potential Therapies for Molecular Delivery  
  MG Damiano, RK Mutharasan, S Tripathy, KM McMahon, CS Thaxton, Adv Drug Deliv Rev, 1/1/2013
• Disruption of ATP-binding cassette B8 in mice leads to cardiomyopathy through a decrease in mitochondrial iron export  
  Ichikawa, Y, Bayeva M, Ghanefar M, Potini V, Sun L, Mutharasan RK, Wu R, Khechaduri A, Naik T, Ardehali H, Proc Natl Acad Sci, 1/13/2012
• Biomimetic high density lipoprotein nanoparticles for nucleic acid delivery  
  McMahon KM, Mutharasan RK, Tripathy S, Veliceasa D, Bobeica M, Shumaker DK, Luthi AJ, Helfand BT, Ardehali H, Mirkin CA, Volpert O, Thaxton CS, Nano Letters, 1/9/2011
• microRNA-210 is upregulated in hypoxic cardiomyocytes through Akt- and p53-dependent pathways and exerts cytoprotective effects  
  Mutharasan RK, Nagpal V, Ichikawa Y, Ardehali, H, American Journal of Physiology, 1/1/2011
• Nanotechnology for synthetic high-density lipoproteins  
  A Luthi, PC Patel, CH Ko, RK Mutharasan, CA Mirkin, CS Thaxton, Trends in Molecular Medicine, 1/1/2010
• Structure and Function of the Sulfonylurea Receptor (SUR) and its Regulation of the Katp Channel  
  MA Burke, RK Mutharasan, H Ardehali, MA Burke, RK Mutharasan, H Ardehali, 1/1/2008
• Computer three-dimensional reconstruction of the atrioventricular conduction system  
  Mutharasan RK, Nagaraj A, Hamilton A, McPherson D, Bharati S, Pacing and Clinical Electrophysiology, 1/1/2004
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Books/Book Chapters

• Gender and Sex Differences in Sports Medicine 
  Chapter: Gender and Sex Differences in Cardiovascular Physiology and Disease 
  G Cascino, RK MutharasanDemos Medical Publishing, New York, NY2016
• Cardiovascular Genetics and Genomics in Clinical Practice 
  Chapter: MicroRNAs 
  RK MutharasanDemos Medical Publishing, New York, NY2015
• Muscle: Fundamental Biology and Mechanisms of Disease 
  Chapter: Cell Therapy for Cardiac Disease 
  RK Mutharasan, DW LosordoAcademic Press, Academic Press2012

Abstracts/Posters

• Apolipoprotein A1 Post-Translational Modifications and High-Density Lipoprotein Efflux Capacity: Preliminary Data from the Chicago Healthy Aging Study.
  JT Wilkins, H Secler, S Thaxton, L Fornelli, P Compton, N Kelleher, RK Mutharasan, M Daviglus, A Sniderman, D Rader, DM Lloyd-Jones, Deuel Conference, Monterrey, CA, 1/1/2017
• Multidisciplinary Heart Failure Transitional Care Team to Impact Readmissions.
  R Fortman, M Fine, A Vlcek, P Goetz, J Rhoades, C Benacka, RK Mutharasan, Journal of the American College of Cardiology, 1/1/2017
• Screening of Patients with Simple Clinical Parameters Early in Hospitalization is Highly Sensitive for Detection of Heart Failure Hospitalization.
  R Fortman, G Astik, P Kansal, H Alphs Jackson, D Navarro, A Anderson, C Davidson, C Yancy, RK Mutharasan, Journal of the American College of Cardiology, 1/1/2017
• Heart Failure Care Transitions: Queuing Theory-based Cost-Effectiveness Analysis of Outpatient Clinic Capacity Sizing.
  RK Mutharasan, P Kansal, H Alphs Jackson, A Anderson, M Abecassis, C Davidson, G Noskin, I Gurvich, J van Mieghem, C Yancy, Journal of the American College of Cardiology, 1/1/2017
• Impact of Multidisciplinary Heart Failure Transitional Care Interventions on Disparities in 30-Day Readmission Rates.
  V Valencia, P Kansal, H Alphs Jackson, R Fortman, A Vlcek, A Anderson, C Davidson, N Soulakis, C Yancy, RK Mutharasan, Journal of the American College of Cardiology, 1/1/2017
• Exertional Chest Pain and Dynamic ST_Segment Changes in a Pregnant Patient with Systemic Lupus Erythematosus.
  RB Patel, RK Mutharasan, M Mendelson, Journal of the American College of Cardiology, 1/1/2017
• Complexity and Collaboration in Discharge Planning for Inpatient Cardiology.
  ND Soulakis, MB Carson, C Frailey, GS Kricke, DM Scholtens, AS Anderson, C Benacka, RK Mutharasan, I Gurvich, JA Van Mieghem, CW Yancy, Circ Cardiovasc Qual Outcomes, 1/1/2016
• Quantifying Teamwork at Hospital Discharge for Readmissions Reduction: A Network Analytics Approach.
  MD Carson, DM Scholtens, CN Frailey, GS Kricke, C Benacka, F Ahmad, RK Mutharasan, P Kansal, AS Anderson, CW Yancy, ND Soulakis, Circ Cardiovasc Qual Outcomes, 1/1/2016
• Leveraging Electronic Health Record Documentation for Failure Mode and Effects Analysis Team Identification on an Inpatient Cardiology Unit.
  GS Kricke, M Carson, YJ Lee, C Benacka, F Ahmad, RK Mutharasan, P Kansal, CW Yancy, AS Anderson, ND Soulakis, Circ Cardiovasc Qual Outcomes, 1/1/2016
• Heart Failure Care Transitions: A Queuing Theory Approach to Match Variable Hospital Discharge Rate with Outpatient Clinic Capacity.
  RK Mutharasan, P Kansal, MM Abecassis, H Alphs Jackson, AS Anderson, C Benacka, JA Berry Jaeker, C Davidson, I Gurvich, D Navarro, GA Noskin, C Schaeffer-Pettigrew, ND..., Circ Cardiovasc Qual Outcomes, 1/1/2016
• Enterprise Data Warehouse-Supported Early Identification of Acute Decompensated Heart Failure Admissions for Efficient and Multidisciplinary Care Team Interventions.
  RK Mutharasan, P Kansal, MM Abecassis, H Alphs Jackson, AS Anderson, C Benacka, JA Berry Jaeker, C Davidson, I Gurvich, D Navarro, GA Noskin, C Schaeffer-Pettigrew, ND..., Circ Cardiovasc Qual Outcomes, 1/1/2016
• Positive Predictive Value of ECG Screening by Seattle Criteria in Collegiate Athletes.
  S Intwala, A Jivan, M Milligan, T Lindley, M Eimer, R Mutharasan, Journal of the American College of Cardiology, 1/1/2016
• Electrocardiogram Utilization in the Marathon Medical Tent.
  JAM Finch, G Chiampas, RK Mutharasan, M Contursi, P D'Hemecourt, S Dyer, C Troyanos, A Baggish, Journal of the American College of Cardiology, 1/1/2016
• Heart Failure Care Transitions: A Queuing Theory Approach to Quantify the Impact of Vacation Periods on Discharge Clinic Wait times.
  RK Mutharasan, P Kansal, H Alphs Jackson, C Benacka, R Fortman, D Navarro, F Ahmad, MM Abecassis, AS Anderson, C Davidson, I Gurvich, G Noskin, N Soulakis, J Van Miegh..., Journal of Cardiac Failure, 1/1/2016
• Hospitalized Heart Failure Incidence is Significantly Underestimated by Diagnosis-Related Group Codes.
  RK Mutharasan, P Kansal, H Alphs Jackson, C Benacka, R Fortman, D Navarro, F Ahmad, MM Abecassis, AS Anderson, C Davidson, G Noskin, N Soulakis, C Yancy, Journal of Cardiac Failure, 1/1/2016
• Pharmacist-led Transitions of Care Interventions Identify and Reduce Medication Errors in Heart Failure Patients Post-Discharge.
  MR Fine, RK Mutharasan, P Kansal, H Alphs Jackson, C Benacka, A Vlcek, R Fortman, C Davidson, AS Anderson, CW Yancy, Journal of Cardiac Failure, 1/1/2016
• Heart Failure Transitions: Staffing Follow-up Clinics to Reduce Readmissions.
  I Gurvich, B Grant, JA van Mieghem, RK Mutharasan, INFORMS, 1/1/2016
• HDL Efflux Capacity, HDL Particle Number, and Carotid Artery Lipid Rich Necrotic Core Plaque: The Chicago Healthy Aging Study.
  J Wilkins, RK Mutharasan, AT Singh, CS Thaxton, M Daviglus, DM Lloyd-Jones, JD Berry, Circulation, 1/1/2015
• HDL Efflux Capacity Correlates with Mean HDL Size and HDL Particle Number: The Chicago Healthy Aging Study.
  RK Mutharasan, JT Wilkins, AT Singh, JD Berry, ML Daviglus, DM Lloyd-Jones, CS Thaxton, Circulation, 1/1/2014
• Lipid Composition of Gold Nanoparticle-Templated High Density Lipoprotein Analogs Dictates Cholesterol Efflux Function.
  RK Mutharasan, A Singh, K McMahon, CS Thaxton, ATVB, 1/1/2014
• Iron Accumulation in the Mitochondria, but not Other Cellular Compartments, Mediates Cardiotoxic Effects of Doxorubicin.
  M Bayeva, Y Ichikawa, M Ghanefar, A Khechaduri, RK Mutharasan, R Wu, TJ Naik, H Ardehali, Circulation, 1/1/2013
• microRNA-145 Regulates ABCA1, SR-B1, and Reverse Cholesterol Transport.
  RK Mutharasan, H Zhang, H Ardehali, CS Thaxton, Circulation, 1/1/2012
• Cardiotoxic Effects of Doxorubicin are Alleviated through Reduction in Mitochondrial Iron.
  M Ghanefar, Y Ichikawa, M Bayeva, A Khechaduri, RK Mutharasan, R Wu, TJ Naik, S Prasad, H Ardehali, Circulation, 1/1/2012
• MicroRNA-210 is Upregulated by Akt Through a Hypoxia Inducible Factor-Independent Mechanism and by p53 Through a Hypoxia Inducible Factor-Dependent Mechanism.
  RK Mutharasan, EJ Wyatt, Y Ichikawa, H Ardehali, Circulation, 1/1/2011
• Characterization of ATP Binding Cassette Protein B8 (ABCB8) as a Mitochondrial Iron and Glutathione Exporter.
  M Bayeva, Y Ichikawa, M Ghanefar, V Potini, L Sun, RK Mutharasan, R Wu, J Kaplan, H Ardehali, Circulation, 1/1/2011
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Lectures

• "Who Pays for the Infrastructure?" 
  Washington, DC - 1/1/2017
• "Lessons Learned: Our Approach to the Heart Failure Bundle." 
  1/1/2017
• "The Stage C Patient: Addressing Readmissions Using a Systems Approach - Solving the Problem?" 
  1/1/2016
• "Athletes and Heart Disease: What's New in 2016?" 
  1/1/2016
• "Heart Failure: The 30,000 Foot View." 
  Methodist Hospital, Merrilville, IN - 1/1/2016
• "A Woman's Prescription for Safe Exercise." 
  1/1/2016
• "Acute Heart Failure Treatment: Setting Up Outpatient Success." 
  1/1/2016
• "Reducing Heart Failure Readmissions: From Global Landscape to Local Approach." 
  1/1/2016
• "That Was Then, This is Now: Medical Education and the Curriculum." 
  1/1/2016
• "Flipped Lectures: Increasing Learner Engagement." 
  1/1/2015
• "Flipping the Script: How the Flipped Classroom Can Increase Learner Engagement." 
  1/1/2015
• "Flipped Lectures." 
  1/1/2015
• "Anticoagulants in Stents and Atrial Fibrillation." 
  1/1/2014
• "The Flipped Classroom." 
  1/1/2013
• "Endocarditis: ACC Meet the Experts Session." 
  Washington, DC - 1/1/2011
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Other

• Educational Medical Videos 
  Mutharasan RK, YouTube Channel
  https://www.youtube.com/user/kannanm