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Office
886 Holmes Rd
Pittsfield, MA 01201Phone+1 202-670-6525Fax+1 888-298-3537
Summary
- Laura Kragie, M.D. is both a licensed physician and a research scientist specializing in Translational Medicine. She heads and owns the consulting firm BioMedWorks® LLC (est. 1997) and in that capacity, has helped many firms grow their pipeline of products through their Translational Sciences program.
Dr. Laura Kragie has contributed significantly to both clinical practice and bench science. She was one of the first doctors in the United States to treat HIV/AIDS patients and more recently, was part of the H1N1 Pandemic Flu Response Team. This reflects her career long involvement with science's and medicine's bleeding edge. Some highlights from her career in Translational Medicine include pioneering work on thyroid hormone/drug membrane transporters, azole inhibition of estrogen synthesis, and gender differences. She contributed to the development of several successful pharmaceuticals, and also identified important safety issues. She is especially interested in Mechanism of Action, Proof of Principle and First in Human studies.
Please go to website for full information: https://www.biomedworks.com
Newletter: https://biomedworks.substack.com
NO INSURANCE ACCEPTED
Education & Training
Massachusetts General HospitalFellowship, 1993 - 1994
University at Buffalo School of MedicineResidency, Physician Scientist/Clin Investigator Pathway Internal Med, 1985 - 1993
University at Buffalo'PhD-like', Mol Pharm, Mol Endo, Mol Immunol, Physician Scientist Award, 1984 - 1993
University of Iowa Hospitals and ClinicsInternship, Internal Medicine, 1983 - 1984
University of Iowa Roy J. and Lucille A. Carver College of MedicineClass of 1983
Certifications & Licensure
MA State Medical License 1994 - 2026
NY State Medical License 1984 - 2000
Awards, Honors, & Recognition
- NIH Director NIAID Group Award for Leading a Comprehensive and Coordinated Response to the H1N1 Influenza Pandemic. NIH, 2010
- FDA Commissioner’s Group Recognition Award as member of "Gender Studies in Product Development Group" US FDA, 1996
- Grant Award Thyroid Hormone Research Advisory Council, 1993-1994
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Publications & Presentations
PubMed
- 175 citationsSex differences in plasma cocaine levels and subjective effects after acute cocaine administration in human volunteersScott E. Lukas, Michelle B. Sholar, Leslie H. Lundahl, X Lamas, Elena M. Kouri
Psychopharmacology. 1996-06-01 - 29 citationsAromatase in primate pregnancy: a review.Laura Kragie
Endocrine Research. 2002-08-01 - 16 citationsMembrane iodothyronine transporters part II: Review of protein biochemistryLaura Kragie
Endocrine Research. 1996-05-01
Journal Articles
- Clonidine in the Treatment of ADHD: Questions about Safety and EfficacyJAMES M. SWANSON, DAVID FLOCKHART, DAN UDREA, DENNIS CANTWELL, DANIEL CONNOR, and LILLIE WILLIAMS., Journal of Child and Adolescent Psychopharmacology 5(4): 301-304, 12/1995
Books/Book Chapters
Abstracts/Posters
- An evaluation of the pharmacokinetic profile of naratriptan in rats following the oral administration of naratriptan combined with eligeno carriers (functional excipie...M Castelli, J Fotso, D Tiano, L Kragie, CLINICAL PHARMACOLOGY & THERAPEUTICS Vol 83 pp S30-S31, 1/1/2008
- POLYCLONAL ANTIBODIES TO BENZODIAZEPINE BINDING-PROTEINS DECREASE TRIIODOTHYRONINE UPTAKE IN MOUSE NEUROBLASTSY LIU, L KRAGIE, R SMIEHOROWSKI, C MARFELLA, M LAKSHMANAN, CLINICAL RESEARCH 42 (2), A267-266, 1994
Other
- BibliographyLaura Kragie
http://www.biomedworks.com
http://www.biomedworks.com/EHF/THbiblio.phtml - EPA EDSTAC Endocrine Disruptor Tier 1 Screen Peer ReviewerLaura Kragie, M.D., EPA
http://www.epa.gov/endo/pubs/assayvalidation/aromatase_pr.htm
2008 - Composition and method of alleviating adverse side effects and/or enhancing efficacy of agents that inhibit aromataseLaura Kragie, USPTO Gazette US 20040192598 A1
https://www.google.com/patents/US20040192598
USPTO - 9/30/2004
Grant Support
- Development of a Relational Database which Incorporates 3-D Structures of Molecular Entities, p450 Structure Activity Relationships and Physico-Chemical PropertiesUS FDA1996–1997
- Thyroid Hormone and Benzodiazepines: Structural Homology and Binding Site InteractionsThyroid Hormone Research Advisory Council1993–1994
- Thyroid Hormone and Cellular Calcium RegulationNIH1988–1993
- In Vitro Hormonal Modulation of Synaptosomal Membrane FunctionsVA Merit Review1985–1990
- Thyroid Hormone and Cellular Calcium RegulationSUNY Buffalo1986–1988
Research History
- Thyroid Hormone Membrane Transporters and Benzodiazepine Interactionshttp://www.biomedworks.com/EHF/THbiblio.phtml1988 - 2002
- Placebo-Controlled Hypertension Trials database projectUS FDA Division CardioRenal Drug Products1995 - 1996
- FellowAcute ETOH effect on estrogen metabolism1993 - 1994
- FellowBuprenorphine Clinical Trial for Opiate Detox and Relapse Prevention1993 - 1994
- Google Scholar Linkhttp://scholar.google.com/citations?user=EyAAtQIAAAAJ&hl=en
Professional Memberships
- Associationshttp://www.biomedworks.com
Other Languages
- French
Industry Relationships
- PROFILE, RESEARCHGATEhttp://www.researchgate.net/profile/Laura_Kragie
- Consultant, BioMedWorks LLC
External Links
- BioMedWorks LLChttps://www.biomedworks.com
- EndoHealthMDhttps://www.laurakragiemd.com
- Newsletterhttps://biomedworks.substack.com
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