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Office
550 1st Ave
Dysautonomia Center Suite 9Q
New York, NY 10016Phone+1 212-263-7225
Summary
- Dr. Jose-Alberto Palma is a neurologist and neuroscientist in New York, NY and is affiliated with NYU Langone Hospitals. He has 15+ years of combined experience in academia (NIH-funded research as principal investigator and laboratory head) and industry. He has been leader/principal investigator in biomarker studies, natural history studies, and clinical trials (phases 1-3) in neurodegenerative disorders (Alzheimer's disease, Parkinson's disease, multiple system atrophy, progressive supranuclear palsy, dementia with Lewy bodies, prion disorders), and rare neurogenetic disorders (familial dysautonomia, ATTR amyloidosis, hereditary sensory, and autonomic neuropathies, congenital insensitivity to pain). He is experienced with diverse therapeutic modalities (AAV, oligonucleotides, antibodies) and regulatory interactions with health authorities. 130+ peer-reviewed publications in top biomedical journals. He is a key opinion leader in the field of neurodegenerative disorders and movement disorders.
Education & Training
- NYU Grossman School of MedicineResidency, Neurology, 2013 - 2015
- New York University School of MedicineAutonomic Disorders, 2013 - 2015
- University of NavarraPh.D., Neuroscience, 2009 - 2013
- Universidad de Navarra Faculty of MedicineClass of 2007
Certifications & Licensure
- NY State Medical License 2017 - 2026
- American Board of Psychiatry and Neurology Neurology
Awards, Honors, & Recognition
- Fellow of the American Academy of Neurology (FAAN) American Academy of Neurology
- Felicia Axerlod Investigator Award American Autonomic Society, 2018
- Don Summers Memorial Award MSA Coalition, 2017
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Clinical Trials
- TD-9855 Phase 2 in Neurogenic Orthostatic Hypotension (nOH) Start of enrollment: 2017 Sep 09
- A Futility Trial of Sirolimus in Multiple System Atrophy Start of enrollment: 2018 Sep 01
- Clinical Effect of Ampreloxetine (TD-9855) for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure Start of enrollment: 2019 Jan 24
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Publications & Presentations
PubMed
- 4 citationsGenome sequence analyses identify novel risk loci for multiple system atrophy.Ruth Chia, Anindita Ray, Zalak Shah, Jinhui Ding, Paola Ruffo
Neuron. 2024-07-03 - 205 citationsNatural history of pure autonomic failure: A United States prospective cohort.Horacio Kaufmann, Lucy Norcliffe-Kaufmann, Jose-Alberto Palma, Italo Biaggioni, Phillip A. Low
Annals of Neurology. 2017-02-01 - 80 citationsα-Synuclein in blood exosomes immunoprecipitated using neuronal and oligodendroglial markers distinguishes Parkinson's disease from multiple system atrophy.Suman Dutta, Simon Hornung, Adira Kruayatidee, Katherine N Maina, Irish Del Rosario
Acta Neuropathologica. 2021-09-01
Journal Articles
- Special Issue on DysautonomiaJose-Alberto Palma, MD, Thieme
- Basal cardiac autonomic tone is normal in patients with periodic leg movements during sleepPalma JA, Alegre M, Valencia M, Artieda J, Iriarte J, Urrestarazu E, J Neural Transm, 1/1/2014
- Predictive factors of the response to treatment with onabotulinumtoxinA in refractory migrainePagola I, Esteve-Belloch P, Palma JA, Luquin MR, Riverol M, Martinez-Vila E, Irimia P, Rev Neurol, 1/1/2014
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Abstracts/Posters
- Depression in Multiple System Atrophy: Impact on Quality of Life and Disease ProgressionMartinez JM, Palma JA, Norcliffe-Kaufmann LJ, Perez M, Kaufmann H, International Society for Autonomic Neuroscience (ISAN) Meeting, Stresa, Italy, 1/1/2015
- Hypotension-induced vasopressin release distinguishes Lewy body disorders from multiple system atrophyPalma JA, Martinez J, Percival L, Fuente-Mora C, Norcliffe-Kaufmann L, Kaufmann H, International Society for Autonomic Neuroscience (ISAN) Meeting, Stresa, Italy, 1/1/2015
- Baseline Features of Patients with Multiple System Atrophy Enrolled in the U.S. Autonomic Disorders Consortium Natural History StudyPalma JA, Norcliffe-Kaufmann L, Martinez J, Perez M, Low P, Singer W, Coon E, Biaggioni I, Robertson D, Peltier A, Freeman R, Gibbons C, Goldstein D, Kaufmann H, - on ..., International Society for Autonomic Neuroscience (ISAN) Meeting, Stresa, Italy, 1/1/2015
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Lectures
- Retinal structure abnormalities as a marker of disease progression in multiple system atrophyPuerto Rico - 1/1/2014
- Knee joint taping improves gait in Familial DysautonomiaNew York, NY - 1/1/2014
- Fractores predictores de respuesta al tratamiento con onabotulinumtoxinA en migrana refractariaBarcelona, Spain - 1/1/2012
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Press Mentions
- This Spinal Cord Implant Zaps Nerve Cells to Help People Learn to Walk AgainApril 7th, 2022
Professional Memberships
- Member
- American Autonomic SocietyMember
- Sleep Research SocietyMember
- International Movement Disorders SocietyMember
Other Languages
- Spanish
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