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Office
1500 E Duarte Road
Duarte, CA 91010Phone+1 626-218-2405Fax+1 626-389-3058
Summary
- I am an assistant professor in the Division of Lymphoma, Department of Hematology and HCT at City of Hope National Medical Center in Duarte, CA. I am boarded in Internal Medicine, Hematology, and Medical Oncology. I have a background in clinical and translational research, and specialize in CAR-T therapies for hematologic malignancies. My particular research interests lie in novel drug development and translational pathobiology for leukemia and lymphoma.
Clinical Expertise
- Hematologic oncology, Myeloproliferative disease, Anemia
Education & Training
Stanford Health CareFellowship, Blood & Bone Marrow Transplant, 2020 - 2021- Stanford Health CarePost-Doctoral Fellowship, 2019 - 2020
- Stanford Health CareFellowship, Hematology and Medical Oncology, 2016 - 2019
University of Pennsylvania Health SystemResidency, Internal Medicine, 2014 - 2016- University of Pennsylvania Health SystemInternship, Internal Medicine, 2013 - 2014
University of Arkansas For Medical Sciences College of MedicineClass of 2013
Certifications & Licensure
CA State Medical License 2016 - 2026
PA State Medical License 2013 - 2016- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Hematology
- American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- Richard V. Ebert Award Dept. of Internal Medicine, UAMS, 2013
- Graduated with Honors in Research UAMS College of Medicine, 2013
- Clinical Research Training Program (CRTP) Fellow OCRTME, National Institutes of Health (NIH), 2012
Clinical Trials
- Natural History of Sickle Cell Disease Start of enrollment: 2004 Apr 29
- Carbon Monoxide Levels and Sickle Cell Disease Severity Start of enrollment: 2012 Jan 26
- CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells With or Without NKTR-255 in Adults With Recurrent or Refractory B Cell Malignancies Start of enrollment: 2017 Sep 01
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Publications & Presentations
PubMed
- 1 citationsAn Unusual Cause of Epistaxis: Paranasal Sinus Myeloid Sarcoma.Karuna Dewan, John H. Baird, Courtney Shires
Case Reports in Hematology. 2019-02-12 - 95 citationsPost-infusion CAR Tcells identify patients resistant to CD19-CAR therapy.Zinaida Good, Jay Y Spiegel, Bita Sahaf, Meena B Malipatlolla, Zach J Ehlinger
Nature Medicine. 2022-09-01 - 290 citationsCAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trialJay Y. Spiegel, Shabnum Patel, Lori Muffly, Nasheed Hossain, Jean Oak
Nature Medicine. 2021-07-26
Books/Book Chapters
Press Mentions
Scotland's Most Promising Scientists Awarded £12 MillionOctober 15th, 2020
Our Great Talent for Invention Will Lead Us Out of Darkness, Says LEO McKINSTRYApril 4th, 2020
Committees
- Ad Hoc Reviewer, British Journal of Haematology Editorial Board 2015 - Present
- Curriculum Author, Hospital of the Univ. of Pennsylvania Dept. of Medicine Nightfloat Curriculum Committee 2014 - 2016
Professional Memberships
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