JianhuaLuoMD

PubMed

• Chloride/proton antiporters ClC3 and ClC5 support bone formation in mice.
  Irina L Tourkova, Quitterie C Larrouture, Silvia Liu, Jianhua Luo, Katherine E Shipman
  Bone Reports. 2024-06-01
• Therapeutic targeting at genome mutations of liver cancer by the insertion of HSV1 thymidine kinase through Cas9-mediated editing.
  Muhamuda Kader, Wei Sun, Bao-Guo Ren, Yan-Ping Yu, Junyan Tao
  Hepatology Communications. 2024-04-01
• The ecto-nucleotide pyrophosphatase/phosphodiesterase 2 promotes early osteoblast differentiation and mineralization in stromal stem cells.
  Irina L Tourkova, Quitterie C Larrouture, Silvia Liu, Jianhua Luo, Paul H Schlesinger
  American Journal of Physiology. Cell Physiology. 2024-03-01

Journal Articles

• Therapeutic targeting at genome mutations of liver cancer by insertion of HSV1 thymidine kinase through Cas9-mediated editing  
  2. Muhamuda Kader, Wei Sun, Bao-Guo Ren, Yan-Ping Yu, Junyan Tao, Lesley M. Foley, Silvia Liu, Satdarshan P. Monga and Jian-Hua Luo, Hepatology
• Novel Fusion Transcripts Associate with Progressive Prostate Cancer  
  Yan P. Yu, Ying Ding, Zhanghui Chen, Silvia Liu, Amantha Michalopoulos, Rui Chen, Zulfiqar G. Gulzar, Bing Yang, Kathleen Cieply, Alyssa Luvison, Bao-Guo Ren, James D...., American Journal of Pathology, 1/1/2014
• Whole Genome Single Nucleotide Polymorphism Array Analysis is Complementary to Classical Cytogenetic Analysis in the Evaluation of Lymphoid Proliferations  
  Sarah E. Gibson, Jianhua Luo, Malini Sathanoori, Jun Liao, Urvashi Surti, George K. Michalopoulos and Steven H. Swerdlow, American Journal of Clinical Pathology, 1/1/2014
• Identification of the Transforming STRN-ALK Fusion as a Potential Therapeutic Target in the Aggressive Forms of Thyroid Cancer  
  Lindsey M. Kelly, Guillermo Barila, Pengyuan Liu, Viktoria N Evdokimova, Sumita Trivedi, Federica Panebianco, Manoj Gadhi, Sally E. Carty Steven Hodak, Jianhua Luo, Sa..., The Proceedings of National Academy of Sciences of USA, 1/1/2014
• High Fidelity Copy Number Analysis of Formalin-Fixed and Paraffin-Embedded Tissues Using Affymetrix Cytoscan HD Chip  
  Yan P. Yu, Amantha Michalopoulos, Ding Ying, George Tseng and Jian-Hua Luo, PLOS ONE, 1/1/2014
• Leukocyte Specific Protein-1: A Novel Regulator of Hepatocellular Proliferation and Migration Deleted in Human HCC  
  Kelly Koral, Shirish Paranjpe, William Bowen, Wendy Mars, Jianhua Luo and George K. Michalopoulos, Hepatology, 1/1/2014
• Whole Genome Methylation Sequencing Reveals Distinct Impact of Differential Methylations on Gene Transcription in Prostate Cancer  
  Yan P. Yu, Ying Ding, Rui Chen, Serena G. Liao, Bao-Guo Ren, Amantha Michalopoulos, George Michalopoulos, Joel Nelson, George C. Tseng and Jian-Hua Luo, American Journal of Pathology, 1/1/2013
• Interaction of MCM7 and RACK1 for Activation of MCM7 and Cell Growth  
  Xi-Yue Zhang, Lang-Zhu Tang, Bao-Guo Ren, Yan P. Yu, Joel Nelson, George Michalopoulos and Jian-Hua Luo, American Journal of Pathology, 1/1/2013
• Metallothionein 1h Tumor Suppressor Activity in Prostate Cancer Is Mediated By Euchromatin Methyltransferase 1  
  Yu-Chen Han, Zhong-Liang Zheng, Ze-Hua Zuo, Yan P. Yu, Rui Chen, George C. Tseng, Joel B. Nelson and Jian-Hua Luo, Journal of Pathology, 1/1/2013
• Regulation of Liver Growth by Glypican 3, CD81, Hedgehog, and Hhex  
  Vishakha S. Bhave, Wendy Mars, Shashikiran Donthamsetty, Xiyue Zhang, Langzhu Tan, Jianhua Luo, William C. Bowen, and George K. Michalopoulos, American Journal of Pathology, 1/1/2013
• Integrin Alpha 7 Binds Tissue Inhibitor of Metalloproteinase 3 to Suppress Growth of Prostate Cancer Cells  
  Lang-Zhu Tan, Yang Song, Joel Nelson, Yan P. Yu and Jian-Hua Luo, American Journal of Pathology, 1/1/2013
• Genome-wide Methylation Analysis of Prostate Tissues Reveals Global Methylation Patterns of Prostate Cancer  
  Jian-Hua Luo, Ying Ding, Rui Chen, George Michalopoulos, Joel Nelson, George Tseng, and Yan P. Yu, American Journal of Pathology, 1/1/2013
• Interaction of CSR1 with XIAP Reverses Inhibition of Caspases and Accelerates Cell Death  
  Zhong-Liang Zheng, Lang-Zhu Tang, Yan P. Yu, George Michalopoulos and Jian-Hua Luo, American journal of Pathology, 1/1/2012
• Exogenous FGF-10 Induces Cystic Lung Development with Altered Target Gene Expression in the Presence of Heparin in Cultures of Embryonic Rat Lung  
  Shuichi Hashimoto, Hiroshi Nakano, Yuko Suguta, Seiko Irie, Luo Jianhua and Sikardar L. Katyal, Pathobiology, 1/1/2012
• Gene Deletions and Amplifications in Human Hepatocellular Carcinomas: Correlation with Hepatocyte Growth Regulation  
  Michael Nalesnik, George Tseng Ying Ding, Guo-Sheng Xiang, Zhong-liang Zheng, Yan Ping Yu, J. Wallis Marsh, George Michalopoulos and Jian-Hua Luo, American Journal of Pathology, 1/1/2012
• p53-Induced-Gene 3 Mediates Cell Death Induced by Glutathione Peroxidase 3  
  Hui Wang, Katherine Luo, Lang-Zhu Tan, Bao-Guo Ren, Li-Qun Gu, George Michalopoulos, Jian-Hua Luo, and Yan P. Yu, Journal of Biological Chemistry, 1/1/2012
• Calpain Induces N-terminal Truncation of Beta-catenin in Normal Murine Liver Development: Diagnostic Implications in Hepatoblastomas  
  Lade A, Ranganathan S, Luo J, Monga SP, Journal of Biological Chemistry, 1/1/2012
• Genome Abnormalities Precede Prostate Cancer and Predict Clinical Relapse  
  Yan P. Yu, Chi Song, George Tseng, Baoguo Ren, William Laframboise, George Michalopoulos, Joel Nelson and Jian-Hua Luo, American Journal of Pathology, 1/1/2012
• Phosphorylation and interaction of Myopodin by Integrin-Link Kinase Lead to Suppression of Cell Growth and Motility in Prostate Cancer Cells  
  Yan-Ping Yu and Jian-Hua Luo, Oncogene, 1/1/2011
• Oncogenic Activity of MCM7 Transforming Cluster  
  Luo, JH, World Journal of Clinical Oncology, 1/1/2011
• Direct Cross-talk between Hepatocyte Growth Factor Receptor (Met) And Insulin Receptor (IR) Via Met-IR Hybrid Receptor: Implication in Hepatic Insulin Resistance and G...  
  Fafalios A, Ma J, Tan X, Stoops J, Luo J, Defrances MC, Zarnegar R, Nature Medicine, 1/1/2011
• Chemotherapeutic Agents in Low Noncytotoxic Concentrations Increase Immunogenicity of Human Colon Cancer Cells  
  Kaneno R, Shurin GV, Kaneno FM, Naiditch H, Luo J, Shurin MR, Cell Oncol, 1/1/2011
• Integrin Alpha 7 Interacts with HtrA2 to Induce Prostate Cancer Cell Death  
  Ze-Hua Zhu, Yan P. Yu, Zhong-Liang Zheng, Yang Song, Guo-Sheng Xiang, Joel Nelson1, George Michalopoulos and Jian-Hua Luo, American Journal of Pathology, 1/1/2010
• (-)-Epigallocatechin-3-gallate Inducing Cell Death through down Regulation of Inhibitor of DNA Binding 2, a Dominant Negative Helix-loop-helix Protein  
  Katherine L. Luo, Jian-Hua Luo, Yan P. Yu, Cancer Science, 1/1/2010
• RNA Interference against Hepatic EGFR Has Suppressive Effects on Liver Regeneration in Rats  
  Shirish Paranjpe, Bowen Liu, George C. Tseng, Jian-Hua Luo and George Michalopoulos, American Journal of Pathology, 1/1/2010
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Books/Book Chapters

• DNA Replication / Book 1 
  Chapter: Regulation of MCM7 DNA Replication Activity 
  Luo, JH and Yan P. Yu2011
• Encyclopedia of Cancer 
  Chapter: Myopodin 
  Yu, Y.P. and Luo, J.H.Editors: M. Schwab.Springer-Verlag, Berlin, Heidelberg2008
• Promoter and CpG Microarrays 
  Chapter: Global Oligonucleotide Methylation Array 
  Page 125 - 140Yu, Y.P. and Luo, J.H.Editors: Neil Winegarden and Mark Takahashi.DNA Press, Eagleville, PA2006
• Progress of Prostate Cancer Research 
  Chapter: Genetics of Human Prostate Cancer 
  Luo, J.H. and Yu, Y.P.Editors: Columbus, F.Nova, New York, NY2004
• Atlas of Genetics and Cytogenetics in Oncology and Haematology 
  Chapter: Soft Tissue Leiomyosarcoma 
  Luo, J.H2004
• Atlas of Genetics and Cytogenetics in Oncology and Haematology 
  Chapter: Myopodin, an Alternative Splice of Synaptopodin 2 
  Luo, J.H.2003
• Gene Expression Analysis 
  Chapter: Differential Subtraction Chain 
  Page 185 - 191Luo, J.H. and Yu, Y.PEditors: Lorkowski, S. and Cullen, P..Wiley-VCH, Weinheim, FRG2002
• Drugs of Today 
  Chapter: Gene Expression Alterations in Human Prostate Cancer 
  Page 713 - 719Luo, J.H.2002
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Abstracts/Posters

• Whole Genome Methylation Sequencing Reveals Distinct Impact of Differential Methylations on Gene Transcription in Prostate Cancer
  Jianhua Luo, Yan P. Yu, Ying Ding, George C. Tseng, Amantha Michalopoulos, Joel B. Nelson, FASEB J, 4/29/2014
• High Fidelity Copy Number Analysis of Formalin-fixed and Paraffin-embedded Tissues Using Affymetrix CytoScan HD Chip
  Jian-Hua Luo, Amantha Michalopoulos, Ying Ding, Yan P, Proceeding of American Association for Cancer Research, 1/1/2014
• Regulation of Liver Growth by Glypican 3, CD81, Hedgehog, and Hhex
  Vishakha Bhave, Wendy Mars, Shashikiran Donthamsetty, Jianhua Luo, William Bowen, and George Michalopoulos, FASEB J, 4/9/2013
• Interaction of MCM7 and RACK1 for Activation of MCM7 and Cell Growth
  Xiyue Zhang, Yan P Yu, and Jian-Hua Luo, FASEB J, 4/9/2013
• Whole Genome and Targeted Next Generation Sequencing in Thyroid Cancer
  Nikiforov, Y; Kelly, L; Durso, MB; Liu, P; Luo, J; Nikiforova, M, MODERN PATHOLOGY, 2/1/2013
• Genome-wide Methylation Analysis of Prostate Tissues Reveals Global Methylation Patterns of Prostate Cancer
  Jian-Hua Luo, Ying Ding, Rui Chen, George Michalopoulos, Joel Nelson, George Tseng, and Yan P. Yu, Proceeding of American Association for Cancer Research, 1/1/2013
• Next Generation Sequencing Analysis to Discover Novel Mutations in Thyroid Cancer
  Kelly LM; Nikiforova MN; Hodak SP; Carty SE; Luo J; Nikiforov YE, University of Pittsburgh Cancer Center Retreat, 6/15/2012
• Global Gene Expression Changes In Regenerating Mouse Liver Following Concurrent Inhibition of MET & EGFR
  Paranjpe, S; Bowen, W; Bhave, V; Luo, JH; Orr, A; Michalopoulos, G, FASEB JOURNAL, 4/1/2012
• Interaction of MCM7 and RACK1 for Activation of MCM7 and Cell Growth
  Xi-Yue Zhang, Yan P. Yu and Jian-Hua Luo, Proceeding of American Association for Cancer Research, 1/1/2012
• Interaction of CSR1 with XIAP Reverses Inhibition of Caspases and Accelerates Cell Death
  Zhong-Liang Zheng, Yan P. Yu and Jian-Hua Luo, SBUR Fall Meeting, Las Vegas, NV, 11/11/2011
• P53 Induced Protein 3 Mediates GPx3 Induced Cell Death
  Hui Wang, Katherine Luo, Jian-Hua Luo, and Yan P. Yu, Proceeding of American Association for Cancer Research, 1/1/2011
• Inhibition of Prostate Cancer Growth and Metastasis Using Small Interference RNA Specific for Minichromosome Complex Maintenance Component 7
  Yi-Kang Shi, Yan P. Yu, George C. Tseng and Jian-Hua Luo, Innovative Minds of Prostate Cancer Research, 1/1/2011
• Interaction between Myopodin and Integrin Linked Kinase (ILK) Induces Tumor Suppression
  Yanping Yu, Hui Wang, and Jian-Hua Luo, Proceeding of American Association for Cancer Research, 1/1/2010
• Integrin Alpha 7 Interacts with HtrA2 to Induce Prostate Cancer Cell Death
  Jian-Hua Luo, Ze-Hua Zhu, Yan P Yu, FASEB J, 1/1/2010
• Integrin Alpha 7 Interacts with HtrA2 to Induce Prostate Cancer Cell Death
  Jian-Hua Luo, Ze-Hua Zhu, Yan P. Yu, Society of Basic Urology Research Fall Meeting, 11/5/2009
• Integrin Alpha7, Mutated in Prostate Cancer, Liver Cancer, Soft Tissue Leiomyosarcoma and Glioblastoma Multiformes, May Be a Tumor Suppressor Gene
  Ren, G, Yan P. Yu and J.H.Luo, VIII Bone and Cancer Society Meeting, Sidney, Australia, 3/25/2009
• (-)-Epigallocatechin-3-gallate Inducing Cell Death through down Regulation of Inhibitor of DNA Binding 2, a Dominant Negative Helix-loop-helix Protein
  Katherine L. Luo, Jian-Hua Luo, Yan P. Yu, Proceeding of American Association for Cancer Research, 1/1/2009
• CSR1 Induces Cell Death through Inactivation of CPSF3
  Jianhua Luo, Zehua Zhu, and Yan P Yu, FASEB J, 1/1/2009
• PI3 Kinase Mediates HGF and EGF Induced Hepatocyte to Biliary Epithelial Cell Transdifferentiation in Organoid Cultures
  PB Limaye, WC Bowen, J Luo, GC Tseng and GK Michalopoulos, Experimental Biology, 1/1/2008
• Abnormal Gene Expression Patterns in Regenerating Liver of Rats Treated with C-Met Silencing Constructs
  Paranjpe S, Bowen WC, Luo JH, Nejak-Bowen K, Michalopoulos GK, FASEB JOURNAL, 1/1/2007
• Role of HGF and EGF Signaling in Transdifferentiation of Hepatocytes to Biliary Epithelium in Organoid Cultures
  Limaye PB, Bowen WC, Luo J, Michalopoulos GK, FASEB JOURNAL, 1/1/2007
• Investigation of the Role of Glypican-3 in Rat Hepatocyte Growth and Liver Regeneration
  Liu B, Bowen WC, Bell AW, Paranjpe S, Mars WM, Nejak-Bowen KN, Luo J, Michalopoulos G, HEPATOLOGY, 1/1/2007
• Cross-organ Classification Analysis in Liver and Prostate Cancer
  Jian-Hua Luo, Yan P. Yu and George Tseng, Proc Amer Assoc Cancer Res, 1/1/2007
• The Mechanism of Myopodin Mediated Prostate Cancer Suppression
  Yan P Yu and Jian-Hua Luo, Society of Basic Urologic Research, 11/6/2006
• MCM7 Amplification and Overexpression Are Associated with Prostate Cancer Progression
  Baoguo Ren, Guoying Yu, George C. Tseng, Kathleen Cieply, George K. Michalopoulos, Joel Nelson, Yan P. Yu, Jian-Hua Luo, Proc Amer Assoc Cancer Res, 1/1/2006
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Lectures

• Prostate Cancer Genome 
  Department of Pathology, University of Pittsburgh School of Medicine - 5/21/2014
• Epigenome and Genome Markers of Prostate Cancer 
  San Antonio, TX - 4/14/2014
• Genomic Markers of Prostate Cancer 
  Xi'An, China - 5/24/2013
• High-throughput Approaches to Analyze Prostate Cancer 
  University of Pennsylvania, Philadelphia, PA - 1/30/2013
• Metallothionein 1h Tumor Suppressor Activity Mediated by Euchromatin Histone Methyl-transferase 
  University of Pittsburgh School of Medicine, Pittsburgh, PA - 5/15/2012
• Genome Pathology for Prostate Cancer 
  University of Pittsburgh, PA - 4/27/2012
• MCM7 Signaling Pathways 
  University of Pittsburgh, PA - 12/5/2011
• Deep Sequencing 
  University of Pittsburgh, Pittsburgh, PA - 9/21/2011
• Genome Analysis of Prostate Cancer 
  Washington, DC - 4/12/2011
• Tumor Suppressor Activity of Integrin Alpha7 
  Department of Pathology, University of Pittsburgh - 10/14/2009
• Integrin Alpha7, Mutated in Prostate Cancer, Liver Cancer, Soft Tissue Leiomyosarcoma and Glioblastoma Multiformes, May Be a Tumor Suppressor Gene 
  Sidney, Australia - 3/26/2009
• Oncogenic Activity of MCM7 
  Department of Pathology, University of Pittsburgh - 6/11/2008
• Tumor Suppressor Activity of CSR1 
  University of Urological Cancer Center, Pittsburgh, PA - 4/14/2008
• Comprehensive Analysis of Methylation Status of Genes in Prostate Cancer 
  San Diego, CA - 4/5/2005
• Characterization of Yyopodin as a Tumor Suppressor Gene 
  University of Pittsburgh Urological Cancer Center, Pittsburgh, PA - 12/3/2004
• Gene Expression Pattern Alterations Precede Morphological Cancer 
  Prouts Neck, MN - 11/6/2004
• Gene Analysis of Malignancy 
  University of Pittrsburgh - 5/12/2003
• Gene Expression Analysis of Prostate Cancer 
  Pittsburgh urologic Cancer Center, University of Pittsburgh - 6/7/2002
• Introduction of Microarray Analysis 
  University of Pittsburgh - 3/12/2002
• Gene Expression Analysis of Prostate Cancers 
  Pittsburgh Urologic Cancer Center, University of Pittsburgh - 6/1/2001
• Genetic Analysis of Prostate Cancers 
  Pittsburgh Urologic Cancer Center, University of Pittsburgh - 12/1/2000
• Analysis of Gene Expression Inactivation in Prostate Cancer 
  Pittsburgh Urologic Cancer Center, University of Pittsburgh - 10/29/1999
• Differential Subtraction Chian 
  Annual Retreat Meeting of Pittsburgh Urologic Cancer Center - 10/5/1999
• Differential Subtraction Chain to Identify Gene Expression Alteration in Prostate Cancer 
  9/13/1999
• Prostate Cancer and Genetic Alteration 
  10/15/1998
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Other

• Genome Copy Number Profiling to Predict Prostate Cancer Clinical Outcomes 
  Luo, JH, UroToday.com
  http://www.urotoday.com/Prostate-Cancer/genome-abnormalities-precede-prostate-cancer-and-predict-clinical-relapse-beyond-the-abstract-by-jianhua-luo-md-phd.html
  1/1/2012