JenniferMarieSpechtMD

Breast Cancer

Jill D. Bennett Endowed Professor Clinical Research Director, Breast Oncology Professor, University of Washington, Division of Medical Oncology Professor, Clinical Research Division, Fred Hutchinson Cancer Center

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Office
1144 Eastlake Ave E.
Seattle, WA 98195
Phone+1 206-606-6889

Education & Training

University of WashingtonFellowship, Hematology and Medical Oncology, 2002 - 2005
University of WashingtonResidency, Internal Medicine, 1999 - 2002
University of Washington School of MedicineClass of 1999

Certifications & Licensure

FL State Medical License 2022 - Present
WA State Medical License 2002 - 2027

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014

Clinical Trials

Sunitinib Malate, Paclitaxel, Doxorubicin Hydrochloride, and Cyclophosphamide Before Surgery in Treating Patients With Stage IIB-IIIC Breast Cancer Start of enrollment: 2007 Jun 01
Completed
Phase 2
FDG PET and DCE-MRI in Predicting Response to Treatment in Patients With Breast Cancer Start of enrollment: 2011 Nov 01
Terminated
Not Applicable
A Safety Study of SGN-LIV1A in Breast Cancer Patients Start of enrollment: 2013 Oct 22
Completed
Phase 1
Genetically Modified T-Cell Therapy in Treating Patients With Advanced ROR1+ Malignancies Start of enrollment: 2016 Mar 16
Terminated
Phase 1
Expanded Access With ABT-888 (Veliparib) to Treat Metastatic Breast Cancer
No longer available
Niraparib in Combination With Trastuzumab in Metastatic HER2+ Breast Cancer Start of enrollment: 2019 Sep 06
Recruiting
Phase 1, Phase 2
T-DM1 and Palbociclib for Metastatic HER2 Breast Cancer Start of enrollment: 2018 Dec 06
Completed
Phase 2
Autologous huMNC2-CAR44 or huMNC2-CAR22 T Cells for Breast Cancer Targeting Cleaved Form of MUC1 (MUC1*) Start of enrollment: 2020 Jan 15
Recruiting
Phase 1
Expanded Access Protocol for Subjects Previously Treated With Gedatolisib in B2151009
Available
Roles: Contact
Niraparib + Dostarlimab In BRCA Mutated Breast Cancer Start of enrollment: 2020 Dec 18
Recruiting
Phase 2
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

Phase 1 Study of ROR1 Specific CAR T Cells in Advanced Hematopoietic and Epithelial Malignancies.
Carla A Jaeger-Ruckstuhl, Jennifer M Specht, Jenna M Voutsinas, Hugh R MacMillan, Qian Vicky Wu
Clinical Cancer Research. 2024-10-28
1 citations
ACR Appropriateness Criteria® Imaging of Invasive Breast Cancer.
, Elizabeth S McDonald, John R Scheel, Alana A Lewin, Susan P Weinstein
Journal of the American College of Radiology. 2024-06-01
7 citations
Gedatolisib in combination with palbociclib and endocrine therapy in women with hormone receptor-positive, HER2-negative advanced breast cancer: results from the dose ...
Rachel M Layman, Hyo S Han, Hope S Rugo, Erica M Stringer-Reasor, Jennifer M Specht
The Lancet. Oncology. 2024-04-01

Journal Articles

Test-Retest Reproducibility of FDG-PET/CT Uptake in Cancer Patients Within a Qualified and Calibrated Local Network
Jennifer M Specht, Jean H Lee, Hannah M Linden, Andrew T Shields, David A Mankoff, Paul E Kinahan, Journal of Nuclear Medicine

Grant Support

Role of ctDNA change as a response measure in the EA1183 patient population and how ctDNA changes correlate with metabolic response by serial FDG PET/CTNCI2021–2026

Professional Memberships

American Society of Clinical Oncology - ASCO
Member