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Office
800 Fairmount Avenue,Suite 215
Pasadena, CA 91105Phone+1 626-817-4701Fax+1 626-817-4701
Summary
- Dr. Jane Chan discovered her passion for medicine through her studies in biology at the University of California, Berkeley, and through her early research focused on chronic inflammation and mitochondrial oxidative damage that became the foundation for her future endeavors. After earning her MD from Sidney Kimmel Medical College at Thomas Jefferson University in Philadelphia, Dr. Chan pursued her fascination with neuroscience and neurodegenerative diseases by completing a neurology residency at the University of California, Davis Medical Center. It was during her neuro-ophthalmology postdoctoral fellowship under the mentorship of Dr. William F. Hoyt at the University of California, San Francisco, that she uncovered the intricate connections between eye and brain diseases.
Now a faculty member and physician-scientist at the Doheny Eye Center and UCLA, Dr. Chan is known for her expertise in diagnosing and managing optic nerve disorders. Her acclaimed textbook, "Optic Nerve Disorders," in its second edition, has become an essential reference for medical students, residents, and fellows.
Dr. Chan's cutting-edge research leverages multi-modal retinal imaging techniques to explore neuro-retinal histopathology at the cellular and molecular levels in pre-Alzheimer’s disease compared to normal aging. Her groundbreaking discoveries in retinal imaging biomarkers provide new insights into the preclinical stages of Alzheimer’s disease, potentially identifying presymptomatic candidates for preventive therapies through the power of artificial intelligence algorithms.
Beyond her research, Dr. Chan is a sought-after lecturer nationally and internationally and holds leadership roles on the editorial boards of major ophthalmology and neurology journals. She is a Fellow of the American Academy of Neurology and the North American Neuro-Ophthalmological Society.
Education & Training
- University of California Davis HealthResidency, Neurology, 1991 - 1995
- Sidney Kimmel Medical College at Thomas Jefferson UniversityClass of 1990
- University of California (San Francisco)Neuro-Ophthalmology
- University of California, BerkeleyBA, Biology, Summa Cum Laude
Certifications & Licensure
- CA State Medical License 1992 - 2026
- NV State Medical License 1999 - 2025
- American Board of Psychiatry and Neurology Neurology
Publications & Presentations
PubMed
- Altering neuronal circuitry with 4-aminopyridine for visual improvement in Leber's hereditary optic neuropathy (LHON).Jane W Chan, William Sultan, Rustum Karanjia, Alfredo A Sadun
Mitochondrion. 2022-01-01 - 5 citationsThe m.3890G>A/MT-ND1 mtDNA rare pathogenic variant: Expanding clinical and MRI phenotypes.Veria Vacchiano, Leonardo Caporali, Chiara La Morgia, Michele Carbonelli, Giulia Amore
Mitochondrion. 2021-09-01 - Re: Chauhan et al.: Differential effects of aging in the macular retinal layers, neuroretinal rim, and peripapillary retinal nerve fiber layer (Ophthalmology. 2020;127...Jane W. Chan, Alfredo A. Sadun
Ophthalmology. 2020-09-01
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